Asthma epidemiology

Respiratory medicine: An asian perspective

Volumn , Issue , 2005, Pages 3-23

  Wong, Gary W K ^a   Chan Yeung, Moira ^b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33845419140     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (162)

1. Beasley R, Crane J, Lai CK, Pearce N. Prevalence and etiology of asthma. Allergy Clin Immunol 2000; 105:S466-72.
2. Lai CKW, Douglass C, Ho SS, Chan J, Lau J, Wong G, Leung R. Asthma epidemiology in the Far East. Clin Exp Allergy 1996; 26:5-12.
3. Nishima S. A study on the prevalence of bronchial asthma in schoolchildren in western districts of Japan as comparison between the studies in 1982 and 1992 with the same methods and same districts. Arerugi 1993; 42:192-204.
4. Hsieh KH, Shen JJ. Prevalence of childhood asthma in Taipei, Taiwan and other Asian Pacific countries. Asthma 1988; 25:73-82.
5. Leung R, Wong GWK, Lau J, Ho A, Chan JKW, Choy D, Douglass C, Lai CKW Prevalence of asthma and allergy in Hong Kong schoolchildren: An ISAAC study. Eur Respir J 1991 10:354-60.
6. Goh DY, Chew FT, Quek SC, Lee BW. Prevalence and severity of asthma, rhinitis, and eczema in Singapore schoolchildren. Arch Dis Child 1996; 74:131-5.
7. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Worldwide variations in the prevalence of asthma symptoms: The International Study of Asthma and Allergies in Childhood (ISAAC). Eur Respir J 1998; 12:315-35.
8. Janson C, Anto J, Burney P. et al. The European Community Respiratory Health Survey: what are the main results so far? European Community Respiratory Health Survey II. Eur Respir J 2001; 18:598-611.
9. von Mutius E, Illi S, Hirsch T, et al Frequency of infections and risk for asthma, atopy and airway hyperresponsiveness children. Eur Respir J 1999; 14:4-11.
10. Weiland SK, von Mutius E, Hirsch T, et al. Prevalence of respiratory and atopic disorders among children in the East and West of Germany five years after unification. Eur Respir J 1999; 14:862-70.
11. Stein RT, Holberg CJ, Morgan WJ, et al. Peak flow variability, methacholine responsiveness and atopy as markers for detecting different wheezing phenotypes in childhood. Thorax 1991 \ 52:946-52.
12. Phankingthongkum S, Daengsuwan T, Visitsunthorn N, et al. How do Thai children and adolescents describe asthma symptoms? Pediatr Allergy Immunol 2002; 13:119-24.
13. Enright PL, McClelland RL, Newman AB, et al. Underdiagnosis and undertreatment of asthma in the elderly. Cardiovascular Health Study Research Group. Chest 1999; 116:603-13.
14. Janssens JP, Pache JC, Nicod LP. Physiological changes in respiratory function associated with ageing. Eur Respir J 1999; 13:197-205.
15. Burney PG, Laitinen LA, Perdrizet S, et al. Validity and repeatability of the IUATLD (1984) Bronchial symptoms Questionnaire: An international comparison. Eur Respir J 1989; 2:940-5.
16. Pekkanen J, Pearce N. Defining asthma in epidemiological studies. Eur Respir J 1999; 14:951-7.
17. Peat JK, Toelle BG, Marks GB, Mellis CM. Continuing the debate about measuring asthma in population studies. Thorax 2001; 56:406-11.
18. Pearce N, Pekkanen J, Beasley R. Role of bronchial responsiveness testing in asthma prevalence surveys. Thorax 2000; 55:352-4.
19. Gibson PG, Henry R. Shah S, Toneguzzi R, Francis JL, Norzila MZ, Davies H. Validation of the ISAAC video questionnaire (AVQ 3.0) in adolescents from a mixed ethnic background. Clin Exp Allergy 2000; 30:1181-7.
20. Sole D, Vanna AT, Yamada E, Rizzo MC, Naspitz CK. International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire: validation of the asthma component among Brazilian children. J Invest Allergo Clin Immunol 1998; 8:376-82.
21. Lai CKW, Chan JKW, Chan A, Wong G, Ho A, Choy D, Lau J, Leung R. Comparison of the ISAAC video questionnaire (AVQ 3.0) with the ISAAC written questionnaire for estimating asthma associated bronchial hyperreactivity. Clin Exp Allergy 1997; 27:540-5.
22. European Community Respiratory Health Survey. Variations in the prevalence of respiratory symptoms, selfreported asthma attacks, and use of asthma medication in the European Community Respiratory Health Survey (ECRHS). Eur Respir J 1996; 9:687-95.
23. Pearce N, Sunyer J, Cheng S, et al. Comparison of asthma prevalence in the ISAAC and the ECRHS. ISAAC Steering Committee and the European Community Respiratory Health Survey. International Study of Asthma and Allergies in Childhood. Eur Respir J 2000; 16:420-6.
24. von Mutius E. The rising trends in asthma and allergic disease. Clin Exp Allergy 1998;J28(suppl 5):45-9.
25. Wieringa MH, Vermeire PA, Brunekreef B, et al. Increased occurrence of asthma and allergy: critical appraisal of studies using allergic sensitization, bronchial hyper-responsiveness and lung function measurements. Clin Exp Allergy 2001; 31:1553-63.
26. Peat JK, van den Berg RH, Green WE et al. Changing prevalence of asthma in Australian children. BMJ 1994; 308:1591-6.
27. Goren Al, Hellmann S. Changing prevalence of asthma among schoolchildren in Israel. Eur Respir J 1991 10:2279-84.
28. von Mutius E, Weiland SK, Fritzsch C, et al. Increasing prevalence of hay fever and atopy among children in Leipzig, East Germany. Lancet 1998; 351:862-6.
29. Burr ML, Butland BK, King S, Vaughau-Williams E. Changes in asthma prevalence: Two surveys 15 years apart. Arch Dis Child 1989; 64:1118-25.
30. Leung R, Ho P. Asthma, allergy, and atopy in three south-east Asians populations. Thorax 1994; 49:1205-10.
31. Wong GW, Li ST, Hui DS, et al. Individual allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children. Eur Respir J 2002; 19:288-93.
32. Wong GW, Hui DS, Chan HH, et al. Prevalence of respiratory and atopic disorders in Chinese schoolchildren. Clin Exp Allergy 2001; 31:1225-31.
33. Ng TP, Hui KP, Tan WC. Prevalence of asthma and risk factors among Chinese, Malaysia and Indian adults in Singapore. Thorax 1994; 49:347-51.
34. Downs SH, Marks GB, Mitakakis TZ, Leuppi JD, Car NG, Peat JK. Having lived on a farm and protection against allergic diseases in Australia. Clin Exp Allergy 2001; 31:570-5.
35. von Ehrenstein OS, von Mutius E, Illi S, Baumann L, Bohm O, von Kries R. Reduced risk of hay fever and asthma among children of farmers. Clin Exp Allergy 2000; 30:187-93.
36. Riedler J, Eder W, Oberfeld G, Schreuer M. Austrian children living on a farm have less hay fever asthma and allergic sensitization. Clin Exp Allergy 2000; 30:194-200.
37. Chan-Yeung M, ZhangLX, Tu DH, et al. The prevalence of asthma and asthma-like symptoms among adults in rural Beijing, China. Eur Respir J 2002; 19:853-8.
38. Beasley R. The burden of asthma with specific reference to the United States. J Allergy Clin Immunol 2002; 109:S482-9.
39. Gergen PJ, Weiss KN. Changing patterns of asthma hospitalization among children: 1979 to 1987. JAMA 1990; 264:1688-92.
40. Williams MH Jr. Increasing severity of asthma from 1960 to 1987. N Engl J Med 1989; 320:1015-6.
41. Pearce N, Beasley R, Crane J, Burgess C. Epidemiology of asthma mortality during the twentieth century. In: Eds. Sheffer AL. Fatal Asthma. New York: Marcel Dekker Inc 1998, 13-9.
42. Ernst P, Spitzer WO, Suissa S, Cockcroft D, Habbick B, Horwitz RI, rt al. Risk of fatal asthma in relation to inhaled corticosteroid use. JAMA 1992; 268:3462-4.
43. Sly RM. Association of decreases in asthma mortality with increases in sales of inhaled corticosteroids [letter] J Allergy Clin Immunol 2000; 105:71-4.
44. Gioldman M, Rachmiel M, Gendler L, Katz Y. Decrease in asthma mortality rate in Israel from 1991-1995: Is it related to increased use of inhaled corticosteroids? J Allergy Clin Immuno 2000; 105:71-4.
45. Tanihara S, Nakamura Y, Oki I, Yanagawa H. Trends in asthma morbidity and mortality in Japan between 1984 and 1996./Epidemiol 2002; 12:217-22.
46. Ng TP, Tan WC. Temporal trends and ethnic variations in asthma mortality in Singapore, 1976-1995. Thorax 1999; 54:990-4.
47. Kumana CR, Kou M, Lauder IJ, Ip MS, Lam WK. Increasing use of inhaled steroids associated with declining asthma mortality. J Asthma 2001; 38:161-7.
48. Postma DS, Kerstjens HAM, Ten Hacken NHT. Asthma: Epidemiology and risk factors. In: Comprehensive Respiratory Medicine. Eds. Albert R, Spiro S, Jett J. London: Mosby, 1999, 40.1-40.
49. Meijer B, Bleecker ER, Postma DS. Genetics. In: Asthma. Basic Mechanism and Clinical Management. Eds. Barnes PJ, Rodger IW, Thomson NC. San Deigo: Academic Press 1998, 35-46.
50. Cookson WO CM., Sharp PA, Faux JA, Hopkins JM. Linkages between immunoglobulin E responses underlying asthma and rhinitis and chromosome llq. Lancet 1992; 1:1292-5.
51. Sanford A, Weir T, Pare P. The genetics of asthma. Am J Respir Crit Care Med 1996; 153:1749-65.
52. Sandford A, Pare P. The genetics of asthma: The important questions. Am J Respir Crit Care Med 2000; 16LS202-6.
53. Van Eerdewegh P, Little RD, Dupuls J, et al. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 2002; 418:426-30.
54. Noguchi E, Shibasaki M, Arinami T, Takeda K, Yokouchi Y, Kobayashi K, Imoto N, Nakahara S, Matsui A, Hamaguchi H. No association between atopy/asthma and the Ile50val polymorphism of IL-4 receptor. Am J Respir Crit Care Med 1999; 160:342-5.
55. Tan EC, et al. IL-4R alpha gene IleVal polymorphism, Allergy 1999; 54:1005-7.
56. Chan H, Lai CKW, Wong GWK, Sandford A, Pare PD, Chan-Yeung M. IL-4 receptor and IL-4 promoter polymorphisms among Hong Kong schoolchildren. Am J Respir Crit Care Med 2001; 16LA202.
57. Li PKT, Lai CKW, Poon ASY, Ho ASS, Chan CHS, Lai KN. Lack of association between HLA-DQ and -DR genotypes and asthma in southern Chinese patients. Clin Exp Allergey 1995; 25:323-31.
58. Wahn U, Lau S, Bergmann R, Kulig M, Forster J, Bergmann K. Indoor allergen exposure is a risk factor for sensitization during the first three years of life. J Allergy Clin Immunol 1991 99:763-9.
59. Platts-Mills TA E, de Week AL. Dust mite allergens and asthma - A world wide problem./Allergy ClinImmunol 1989: 83:416-27.
60. Platts-Mills TA E, Thomas WR, Aalberse RC, Vervloet D, Chapman MD. Dust mite allergens and asthma: Report of a second international workshop. J Allergy Clin Immunol 1992; 89:1046-60.
61. Leung R., Lam CW K, Ho A, Chan JK W, Choy D, Lai CK W. Allergic sensitization to common environmental allergens in adult asthmatics in Hong Kong. HKMJ 1997; 3:211-7.
62. Platts-Mills TA E, Vervlet D, Thomas WR, Aalberse RC, Chapman MD. Indoor allergens and asthma: Report of the third international workshop. J Allergy Clin Immunol 1997; 100:S1-S24.
63. Peat JK, Tovey E, Toelle BG, Haby MM, Gray EJ, Mahmic A, Woolcock AJ. House dust mite allergens. A major risk factor for childhood asthma in Australia. Am J Respir Crit Care Med 1996; 153:141-6.
64. Lau S, Falkenhorst G, Weber A, Werthmann I, Lind P, Buettner-Goetz P, Wahn U. High mite-allergen exposure increases the risk of sensitization in atopic children and young adults. J Allergy Clin Immunol 1989; 84:718- 25.
65. Sporik R, Holgate S, Platts-Mills T, Coswell J. Exposure to house-dust mite allergen (Der pi) and the development of asthma in childhood. N Engl J Med 1992; 323:502-7.
66. Chan-Yeung M, Manfreda J, Dimich-Ward J, Lam J, Ferguson A, Warren P, Simons E, Broder I, Chapman M, Platts-Mills TA E., Becker A. Mite and cat allergen levels in homes and severity of asthma. Am J Respir Crit Care Med 1995; 152:1805-11.
67. Kivity S, Solomon A, Soferman R, Schwarz Y, Mumcuoglu K, Topilsky M. Mite asthma in childhood. A study of the relationship between exposure to house dust mite and disease activity. J Allergy Clin Immunol 1993; 91:844-9.
68. Peat JK, Tovey E, Gray EJ, Mellis CM, Woolcook AJ. Asthma severity and morbidity in a population sample of Sydney school children: Part II. Importance of house dust mite allergen. Aust NZJ Med 1994; 24:270-6.
69. Halonen M, Stern DA, Wright AL, Taussig LM, Martinez FD. Alternaria as a major allergen for asthma in children raised in a desert environment. Am J Respir Crit Care Med 1997; 155:1356-61.
70. Sporik R, Ingram JM, Price W, Sussman JH, Honsinger RW, Platts-Mills TAE. Association of asthma with serum IgE and skin tests reactivity to allergen among children living at high altitude: Tickling the dragon's breath. Am J Respir Crit Care Med 1995; 151:1388-92.
71. Gold DR, Burge HA, Carey V, Milton FK, Platts-Mills TAE, Weiss ST. Predictors of repeated wheeze in the first year of life. Am J Respir Crit Care Med 1999; 160:227-36.
72. Burr ML, Miskelly FG, Butland BK, Merrett TG, Vaughan-William E. Environmental factors and symptoms in infants at high risk of allergy. J Epdemiol Community Health 1989; 43:125-32.
73. Nafstad P, Oie L, Mehl R, Gaarder PI, Lodrup-Carlsen KC, Botten G, et al. Residential dampness problems ad symptoms and signs of bronchial obstruction in young Norwegian children. Am J Respir Crit Care Med 1998; 157:410-4.
74. Lau S, Illi S., Sommerfield C, Niggermann B, Bergmann R, von Mutius E, et al. Early exposure to house dust mite and cat allergens and development of childhood asthma: A cohort study. Multicentre Allergy Study Group. Lancet 2000; 356:1392-7.
75. Brunekreef B, Groot B, Hoek G. Pets, allergy and respiratory symptoms in children. Int J Epidemiol 1992; 21:338-2.
76. Kjellrnan B, Pettersson R. The problem of furred pets in childhood atopic disease. Failure of an information program. Allergy 1983; 38:65-73.
77. Custovic A, Green R, Fletcher A, Smith A, Picke AC, Chapman M, Woodcock A. Aerodynamic properties of the major dog allergen Can f 1: distribution in homes, concentration, and particle size of allergen in the air. Am J Respir Crit Care Med 1997; 155:94-8.
78. Ingram JM, Sporik R, Rose G, Honsinger R, Chapman MD, Platts-Mills TAE. Quantitative assessment of exposure to dog (Can f 1) and cat (Fel dl) allergens: relationship to sensitization and asthma among children living in Los Alamos, New Mexico. J Allergy Clin Immunol 1995; 96:449-56.
79. Quirce S, Dimich-Ward H, Chan H, Ferguson A, Becker A, Manfreda J, Simons E, Chan-Yeung M. Major cat allergen (Fel dl) in the homes of patients with asthma and their relationship to sensitization to cat dander. Ann Allergy Asthma Immunol 1995; 75:325-30.
80. Enberg RN, Shamie SM, McCullough J, Ownby DR. Ubiquitous presence of cat allergen in cat-free buildings: probable dispersal from human clothing. Ann Allergy 1993; 70:471-1.
81. Munir AK M, Einarsson R, Schou C, Dreberg SK Allergens in school dust. I. The amount of the major cat (Fel dl) and dog (Can fl) allergens in dust from Swedish schools is high enough to probably cause perennial symptoms in most children with asthma who are sensitized to cat and dog./Allergy Clin Immunol 1993; 91:1067-74.
82. Leung R, Lam WK, Chan A, Lee M, Chan HS, Pang SW Lai CKW. Indoor environment of residential homes in Hong Kong - relevance to asthma and allergic disease. Clin Exp Allergy 1998; 28:585-90.
83. Noertjojo K, Dimich-Ward H, Obata H, Manfreda J, Chan-Yeung M. Exposure and andomizedon to cat dander: Asthma and asthma-like symptoms. J Allergy Clin Immunol 1999; 103:60-5.
84. Svanes C, Jarvis D, Chinn S, Burney P. Childhood environment and adult atopy: results from the European Community Respiratory Health Survey. J Allergy Clin Immunol 1999; 103:415-20.
85. Roost H-P, Kunil N, Schindler C, Jarvis D, et al. Role of current and childhood exposure to cat and atopic sensitizatioin. J Allergy Clin Immunol 1999; 104:941-7.
86. Remes ST, Castro-Rodriguez J A, Hollberg CJ, Martinez FD, Wright AL. Dog exposure in infancy decrease the subsequent risk of frequent wheeze but not of atopy. J Allergy Clin Immunol 2001; 108:509-15.
87. Apelberg BJ, Aoki Y, Jaakkola JJK. Systematic review: exposure to pets and risk of asthma and asthma-like symptoms. J Allergy Clin Immunol 2001; 107:455-60.
88. Arruda LK, Vailesa LD, Mann BJ, Shannon J, Fox JW, Vedvisk TS, et al. Molecular cloning of a major cockroach (Blattella germanica) allergen, Bla g2. J Biol Chem 1995; 270:19563-8.
89. Sarpong SB, Hamilton RG, Eggleston PA, Adkinson NF Jr. Socio-economic status and race as risk factors for cockroach allergen exposure and sensitization in children with asthma. J Allergy Clin Immunol 1996; 97:1393- 01.
90. Kang BC, Johnson J, Veres-Thorner C. Atopic profile of inner-city asthma with a comparative analysis on the cockroach-sensitive and ragweed-sensitive subgroups. J Allergy Clin Immunol 1993; 92:1393-401.
91. Rosenstreich D.L., Eggleston P., Kattan M, Baker D, Slavin RG, Gergen P, Mitchell H, McNiff-Mortimer K, Lynn H, Ownby D, Malveaux F. The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner city children with asthma. N Eng J Med 1997; 336:1356-63.
92. Yang C, Tien Y, Hsieh H, Kao W, Lin M. Indoor environmental risk factors and childhood asthma: A casecontrol study in subtropical area. Paediatr Pulmonol 1998; 26:120-4.
93. Dales R, Burnett R, Zwanenburg H. Adverse health effects among adults exposed to home dampness and molds. Am Rev Respir Dis 1991; 143:505-9.
94. Hide D, Matthews S, Matthews L, Stevens M, Rideout S, Twiselton R, Gant C, Arshad S. Effect of allergen avoidance in infancy on allergic manifestations at age of two years. J Allergy Clin Immunol 1994; 93:842-6.
95. Zeiger RS, Heller S. The development and prediction of atopy in high-risk children: Follow up at age seven years in a prospective andomized study of combined maternal and infant food allergen avoidance. 7 Allergy Clin Immunol 1995; 95:1179-90.
96. Marini A, Agosti M, Motta G, Mosca F. Effects of a dietary and environmental prevention programme on the incidence of allergic symptoms in high atopic risk infants: Three years follow-up. Acta Pediatr Suppl 1996; 414:1-22.
97. Sigurs N, Bjarnason R, Sigurbergsson F, Kjellman B. Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med. 2000; 161:1501-7.
98. Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ, and the group health medical associates. Asthma and wheezing in the first six years of life. TV Engl J Med 1995; 332:133-8.
99. Shaheen SO, Aabt P, Hall AJ, Barker DJP, HEYES CB, Shiell AW, et al. Measles and atopy in Guinea-Bissau. Lancet 1996; 347:1792-6.
100. Matricardi PM, Rosmini F, Ferrigno L, Nisini R, Rapicetta M, Chionne P, Stroffolini T, Pasquini P, D'Amelio R. Cross-sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus. BMJ 1991 \ 314:999-1007.
101. Matricardi PM FF, Franco A, Caprio G, Murru F, Cioffi D, Ferrigno L, Palermo A, Ciccarelli N, Rosmini F. Sibship size, birth order, and atopy in 11371 Italian young men. J Allergy Clin Immunol 1998; 101:439-4.
102. Shirakawa T, Enomoto T, Shimazu S, Hopkin JM. The inverse association between tuberculin responses and atopic disorder. Science 1991 \ 275:77-9.
103. von HertzenL, Klaukka T, Mattila H, et al. Mycobacterium tuberculosis infection and the subsequent development of asthma and allergic conditions. J Allergy Clin Immunol 1999; 104:1211-4.
104. Omenaas E, Jentoft HF, Vollmer WM, et al. No relationship between tuberculin reactivity and atopy in BCG vaccinated young adults. Thorax 2000; 55:454-8.
105. Wong GW, Hui DS, Tarn CM, Chan HH, Fok TF, Chan-Yeung M, Lai CK. Asthma, atopy and tuberculin responses in Chinese schoolchildren in Hong Kong. Thorax 2001; 56:770-3.
106. Strachan DP. Hay fever, hygiene, and household size. BMJ 1989; 299:1259-60.
107. Strachan DP, Harkins LS, Johnston ID, Anderson HR. Childhood antecedents of allergic sensitization in young British adults. J Allergy Clin Immunol 1997: 99:6-12.
108. Shaheen SO. Changing patterns of childhood infection and the rise in allergic disease. Clin Exp Allergy 1995; 25:1034-7.
109. Kramer U, Heinrich J, Wjst M, Wichmann HE. Age of entry to day nursery and allergy in later childhood. Lancet 1999; 353:450-4.
110. Romagnani S. The Thl/Th2 paradigm and allergic disorders. Allergy 1998; 53(46 Suppl):12-5.
111. Zhao TB, Wang A, Chen Y, Xiao M, Duo L, Liu G, Lau YL, Karlberg J. Prevalence of childhood asthma, allergic rhinitis and eczema in Hong Kong, Urumqi and Beijing. J Paediatr Child Health 2000; 36:128-33.
112. Braun-Fahrlander CH, Gassner M, Grize L, Neu U, Sennhauser FH, Varonier HS, Vuille JC, Whthrich B and the Scarpol Team. Prevalence of hay fever and allergic sensitization in farmer's children and their peers living the same rural community. Clin Exp Allergy 1999; 29:28-34.
113. Ernst P and Cormier Y Relative scarcity of asthma and atopy among rural adolescents raised on farm. Am J Respir Crit Care Med 2000; 161:1563-6.
114. Kilpelinen M, Terho EO, Helenius H and Koskenvuo M. Farm environment in childhood - prevents the development of allergies. Clin Exp Allergy 2000; 30:201-8.
115. Martinez FD. Maturation of immune responses at the beginning of asthma. J Allergy Clin Immunol 1999; 103:355-61.
116. Holt PG, Sly PD, Bjorksten B. Atopic versus infections diseases in childhood: A question of balance. Pediatr Allergy Immunol 1997; 8:53-8.
117. Braun-Fahrlander C, Riedler J, Herz U, Eder W, Waser M, Grize L, Maisch S, Carr D, Gerlach F, Bufe A, Lauener RP, Schierl R, Renz H, Nowak D, von Mutius E. Environmental exposure to endotoxin and its relation to asthma in school-age children. TV Engl J Med 2002; 347:869-77.
118. Viegi G, Enarson D. Human health effects of air pollution from mobile sources in Europe. Int J Tuberc Lung 1998; 2:947-67.
119. World Health Organization. Guidelines for air quality. WHO, Geneva 1999. www.who.int/peh/air/aorguides2.htm.
120. Vedal S, Petkau J, White R, Blair J. Acute effects of ambient inhalable particles in asthmatic and nonasthmatic children. Am J Respir Crit Care Med 1998; 157:1-10.
121. Wong TW, Lau TS, Yu TS, Neller A, Wong SL, Tarn W, Pang SW. Air pollution and hospital admission for respiratory and cardiovascular diseases in Hong Kong. Occup Environ Med 1999; 56:679-83.
122. Wong GWK, Ko FWS, Lau TA, Li ST, Hui D, Pang SW, Leung R, Fok TF, Lai CKW. Temporal relationship between air pollution and hospital admissions for asthmatic children in Hong Kong. Clin Exp Allergy 2001; 31:565-9.
123. Vedal S, Brurnm J, Brauer M, Tsui M, Tong HK, Wong YK, Petkau J, Chan-Yeung M Acute effects of air pollution on asthma emergency room visits in Hong Kong. Am J Respir Crit Care Med 2001; 16LA562.
124. Roemer W, Hoek G, Brunekreef B. Pollution effects on asthmatic children in Europe, the PEACE study. Clin Exp Allergy 2000; 30:1067-75.
125. Dockery DW, Pope CA. Acute respiratory effects of particulate air pollution. Annu Rev Public Health 1994; 15:107-32.
126. Ishizaki T, Koizumi K., Ikemori R, Ishyama Y, Kushibiki E. Studies of prevalence of Japanese cedar pollinosis among the residents in a densely cultivated area. Ann Allergy 1987; 58:265-70.
127. Brunekreef B, Janssen NA, de Hartog J, Harssema H, Knape M, van Vliet P. Air pollution from truck traffic and lung function in children living near motorways. Epidemiol 1991 \ 8:298-303.
128. Nitta H, Sato T. Nakai S, Maeda K, Aoki S, Ono M. Respiratory Health associated with exposure to automobile exhaust. I. Results of cross-sectional studies in 1979, 1982, 1983. Arch Environ Health 1993: 48:53-8.
129. Oosterlee A. Drijver M, Lsbert E, Brunekreef B. Chronic respiratory symptoms in children and adults living along streets with high traffic. Occup Environ Med 1996; 53:241-7.
130. Hirsch TH, Weiland SK, von Mutius E, Safeca AF, Grafe H, Csaplovics E, et al. Inner city air pollution and respiratory health and atopy in children. Eur Respir J 1999; 14:669-77.
131. Wang TN, Ko YC, Chao YY, Huang CC, Lin RS. Association between indoor and outdoor air pollution and adolescent asthma from 1995 to 1996 in Taiwan. Environ Research 1999; 81:239-7.
132. Ong SG, Wong CM, Tam TH, Tam AYC, Dainel L, Hedley AJ. Studies on the respiratory health of primary school children in urban communities of Hong Kong. The Science of Total Environment 1991; 106:121-35.
133. Tam A, Wong C, Lam T, Ong S, Peters J, Hedley A. Bronchial responsiveness in children exposed to atmospheric pollution in Hong Kong. Chest 1994; 106:1056-60.
134. Wong CM, Lam TH, Peters J, Hedley AJ, Ong SG, Tam AY C, Liu J, Spiegelhalter DJ. Comparison between two districts of the effects of an air pollution intervention on bronchial responsiveness in primary school children in Hong Kong. Int J Epidmiol Community Health 1998; 52:571-8.
135. Terada N, Maesako K, Hiruma K, Hamano N, Houki G, Konno A. Diesel exhaust particulates enhance eosinophil adhesion to nasal epithelial cells and cause degranulation. Int Arch Allergy Immunol 1997; 114:167- 74.
136. Hedley AJ, Wong C-M, Thach TQ, Ma S, Lam TH, Anderson HR. Cardiorespiratory and all-cause mortality after restrictions on sulphur content of fuel in Hong Kong: An intervention study. Lancet 2002; 360:1646-52.
137. Diaz-Sanchez D, Dotson AR, Takeneka H, Saxon A. Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms. J Clin Invest 1994; 94:1417-25.
138. Strachan DP, Cook DG. Passive smoking and lower respiratory illness in infancy and childhood. Thorax 1991; 52:905-14.
139. Chen Y, Li W, Yu S. Influence of passive smoking on admissions for respiratory illness in early childhood. BMJ 1986; 293:303-6.
140. Cook DG, Strachan DP. Health effects of passive smoking: 3. Parental smoking and prevalence of respiratory symptoms and asthma in school age children. Thorax 1991 52:1081-94.
141. Neuspiel DR, Rush D, Butler NR, Golding J, Bijur PE, Kerzon M. Parental smoking and post-infancy wheezing in children: A prospective cohort study. Am J Public Health 1989; 79:168-71.
142. Murray AB, Morrison BJ. The effect of cigarette smoke from the mother on bronchial responsiveness and severity of symptoms in children with asthma. J Allergy Clin Immunol 1986; 77:575-81.
143. Ehrlich RI, Du Toit D, Jordaan E, Zwarenstein M, Potter P, Volmink JA, Weinberg E. Risk factors for childhood asthma and wheezing: importance of maternal and household smoking. Am J Respir Crit Care Med 1996; 154:681-8.
144. Martinez F, Antognoni G, Marci F, et al. Parental smoking enhances bronchial responsiveness in nine-year old children. Am Rev Respir Dis 1988; 138:518-23.
145. Gortmaker S, Walker DK, Jacobs FH, Rich-Ross H. Parental smoking and the risk of childhood asthma. Am J Pub Health 1982; 72:574-9.
146. Weitzman M, Gortmaker S, Walker D, Sobol A. Maternal smoking and childhood asthma. Pediatr 1990; 85:505-11.
147. Troiano RP, Flegal KM, Kuczmarski RJ, Campbell SM, Johnson CL. Overweight prevalence and trends for children and adolescents. The National Health and Nutrition Examination Survey. 1963-1991. Arch PedAdoles Med 1995; 149:1085-91.
148. Gortmaker SL, Must A, Sobol AM, Peterson K, Colditz GA, Dietz WH. Television watching as a cause of increasing obesity among children in the United states. 1986-1990. Arch Pediatr adolesc med 1995; 149:1085- 91.
149. Crater SE, Platts-Mills TAE. Searching for the cause of the increase in asthma. Current Opinion in Pediatrics 1998; 10:594-9.
150. Platts-Mills TAE, Sporik RB, Chapman MD, Heymann PW The role of domestic allergens. Ciba Found Symp 1991 206:173-89.
151. Lazarus R, Colditz G, Berkey CS, Speizer FE. Effects of body fat on ventilatory function in children and adolescents. Pediatr Pulmonol 1997; 24:187-94.
152. Howie PW, Forsyth JS, Ogston SA, Clark A. V, du Florey C. Protective effect of breast-feeding against infection. BMJ 1990; 300:11-6.
153. Wold AE, Alderberth I. Does breastfeeding alter the infant's immune responsiveness? Acta Pediatr 1998; 87:946-9.
154. McConnochie KM, Roghmann KJ. Breast feeding and maternal smoking as predictors of wheezing in children 6 to 10 years of age. Pediatr Pulmonol 1986; 2:260-8.
155. Burr ML, Limb ES, Maguire MJ, et al. Infant feeding, wheezing and allergy: A prospective study. Arch Dis Child 1993; 68:724-8.
156. Wright Al, Holberg CJ, Taussig LM, Martinez FD. Relationship of infant feeding to recurrent wheezing at age 6 years. Arch Pediatr Adolesc Med 1995; 149:758-63.
157. Peat JK, Li J. Reversing the trend: reducing the prevalence of asthma. J Allergy Clin Immunol 1999; 103:1- 10.
158. Britton J, Pavord I, Richards K, et al. Dietary sodium intake and the risk of airway hyperreactivity in a random adult population. Thorax 1994; 59:875-80.
159. Schwartz J, Speizer FE. The relationship of dietary fish intake to level of pulmonary function in the first National Health and Nutrition Survey (NHANES I). Eur Respir J 1994; 7:1821-4.
160. Weiss ST. Diet as a risk factor for asthma. The rising trends in asthma. Ciba Foundation Symposium 206. Chichester Wiley 1997, 244-57.
161. Peat JK, Salome CM, Woolcock AJ. Factors associated with bronchial hyperresponsiveness in Australian adults and children. Eur Respir J 1992; 5:921-9.
162. Hodge L, Salome CM, Hughes JM, et al. Effect of dietary intake of omega-3 and omega6 fatty acids on severity of asthma in children. Eur Respir J 1991 11:361-5.