On the role of glypicans in the process of morphogen gradient formation

Developmental Biology

Volumn 300, Issue 2, 2006, Pages 512-522

  Hufnagel, Lars ^a   Kreuger, Johan ^b   Cohen, Stephen M ^c   Shraiman, Boris I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Dally like; Diffusion; Glypican; Gradient; Morphogen; Wingless

Indexed keywords

DALLY LIKE PROTEIN; GLYPICAN; MORPHOGEN; PROTEIN; WNT1 PROTEIN;

ARTICLE; CELL SURFACE; DROSOPHILA MELANOGASTER; FORELIMB; GENE OVEREXPRESSION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION;

DROSOPHILA MELANOGASTER;

EID: 33845418128     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2006.08.076     Document Type: Article

References (44)

1. Baeg G.H., Lin X., Khare N., Baumgartner S., and Perrimon N. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development 128 1 (2001) 87-94
2. Baeg G.H., Selva E.M., Goodman R.M., Dasgupta R., and Perrimon N. The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors. Dev. Biol. 276 (2004) 89-100
3. Barkai N., and Leibler S. Robustness in simple biochemical networks. Nature 387 (1997) 913-917
4. Belenkaya T.Y., Han C., Yan D., Opoka R.J., Khodoun M., Liu H., and Lin X. Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans. Cell 119 (2004) 231-244
5. Bernfield M., Kokenyesi R., Kato M., Hinkes M.T., Spring J., Gallo R.L., and Lose E.J. Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans. Annu. Rev. Cell Biol. 8 (1992) 365-393
6. Bernfield M., Gotte M., Park P.W., Reizes O., Fitzgerald M.L., Lincecum J., and Zako M. Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem. 68 (1999) 729-777
7. Brook W.J., and Cohen S.M. Antagonistic interactions between wingless and decapentaplegic responsible for dorsal-ventral pattern in the Drosophila leg. Science 273 (1996) 1373-1377
8. Cinquin O. Fast-tracking morphogen diffusion. J. Theor. Biol. 238 (2006) 532-540
9. Crickmore M.A., and Mann R.S. Hox control of organ size by regulation of morphogen production and mobility. Science 313 (2006) 63-68
10. Eldar A., and Barkai N. Interpreting clone-mediated perturbations of morphogen profiles. Dev. Biol. 278 (2005) 203-207
11. Eldar A., Dorfman R., Weiss D., Ashe H., Shilo B.Z., and Barkai N. Robustness of the BMP morphogen gradient in Drosophila embryonic patterning. Nature 419 (2002) 304-308
12. Eldar A., Rosin D., Shilo B.Z., and Barkai N. Self-enhanced ligand degradation underlies robustness of morphogen gradients. Dev. Cell 5 (2003) 635-646
13. Eldar A., Shilo B.Z., and Barkai N. Elucidating mechanisms underlying robustness of morphogen gradients. Curr. Opin. Genet. Dev. 14 (2004) 435-439
14. Entchev E.V., Schwabedissen A., and Gonzalez-Gaitan M. Gradient formation of the TGF-beta homolog Dpp. Cell 103 (2000) 981-991
15. Esko J.D., and Lindahl U. Molecular diversity of heparan sulfate. J. Clin. Invest. 108 (2001) 169-173
16. Franch-Marro X., Marchand O., Piddini E., Ricardo S., Alexandre C., and Vincent J.P. Glypicans shunt the Wingless signal between local signalling and further transport. Development 132 (2005) 659-666
17. Fujise M., Izumi S., Selleck S.B., and Nakato H. Regulation of dally, an integral membrane proteoglycan, and its function during adult sensory organ formation of Drosophila. Dev. Biol. 235 (2001) 433-448
18. Giraldez A.J., Copley R.R., and Cohen S.M. HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient. Dev. Cell 2 (2002) 667-676
19. Goodwin G.C., Graebe S.F., and Salgado M.E. Control System Design (2001), Prentice Hall, New York
20. Han C., Yan D., Belenkaya T.Y., and Lin X. Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc. Development 132 (2005) 667-679
21. Held L.I.J. Imaginal Discs: Thr Genetic and Cellular Logic of Pattern Formation (2002), Cambridge Univ. Press, Cambridge, UK
22. Jackson S.M., Nakato H., Sugiura M., Jannuzi A., Oakes R., Kaluza V., Golden C., and Selleck S.B. dally, a Drosophila glypican, controls cellular responses to the TGF-beta-related morphogen, Dpp. Development 124 (1997) 4113-4120
23. Kerszberg M., and Wolpert L. Mechanisms for positional signalling by morphogen transport: a theoretical study. J. Theor. Biol. 191 (1998) 103-114
24. Kirkpatrick C.A., Dimitroff B.D., Rawson J.M., and Selleck S.B. Spatial regulation of Wingless morphogen distribution and signaling by Dally-like protein. Dev. Cell 7 (2004) 513-523
25. Kreuger J., Lindahl U., and Jemth P. Nitrocellulose filter binding to assess binding of glycosaminoglycans to proteins. Methods Enzymol. 363 (2003) 327-339
26. Kreuger J., Perez L., Giraldez A.J., and Cohen S.M. Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity. Dev. Cell 7 (2004) 503-512
27. Lander A.D., Nie Q., and Wan F.Y. Do morphogen gradients arise by diffusion?. Dev. Cell 2 (2002) 785-796
28. Lawrence P.A., and Struhl G. Morphogens, compartments, and pattern: lessons from Drosophila?. Cell 85 (1996) 951-961
29. Levin M.D., Shimizu T.S., and Bray D. Binding and diffusion of CheR molecules within a cluster of membrane receptors. Biophys. J. 82 (2002) 1809-1817
30. Lin X., and Perrimon N. Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature 400 (1999) 281-284
31. Lin X., and Perrimon N. Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila. Matrix Biol. 19 (2000) 303-307
32. Marois E., Mahmoud A., and Eaton S. The endocytic pathway and formation of the Wingless morphogen gradient. Development 133 (2006) 307-317
33. Nolo R., Abott L.A., and Bellen H.J. Senseless, a Zn finger transcription factor is necessary and sufficient for sensory organ development in Drosophila. Cell 102 (2000) 349-362
34. Orsulic S., and Peifer M. Cell-cell signalling: Wingless lands at last. Curr. Biol. 6 (1996) 1363-1367
35. Pellegrini L., Burke D.F., von Delft F., Mulloy B., and Blundell T.L. Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin. Nature 407 (2000) 1029-1034
36. Perrimon N., and Bernfield M. Specificities of heparan sulphate proteoglycans in developmental processes. Nature 404 (2000) 725-728
37. Rives A.F., Rochlin K.M., Wehrli M., Schwartz S.L., and DiNardo S. Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing. Dev. Biol. 293 (2006) 268-283
38. Selleck S.B. Genetic dissection of proteoglycan function in Drosophila and C. elegans. Semin. Cell Dev. Biol. 12 (2001) 127-134
39. Seto E.S., and Bellen H.J. The ins and outs of Wingless signaling. Trends Cell Biol. 14 (2004) 45-53
40. Seto E.S., and Bellen H.J. Internalization is required for proper Wingless signaling in Drosophila melanogaster. J. Cell Biol. 173 (2006) 95-106
41. Strigini M., and Cohen S.M. Wingless gradient formation in the Drosophila wing. Curr. Biol. 10 (2000) 293-300
42. Tabata T., and Takei Y. Morphogens, their identification and regulation. Development 131 (2004) 703-712
43. Tsuda M., Kamimura K., Nakato H., Archer M., Staatz W., Fox B., Humphrey M., Olson S., Futch T., Kaluza V., Siegfried E., Stam L., and Selleck S.B. The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila. Nature 400 (1999) 276-280
44. Yayon A., Klagsbrun M., Esko J.D., Leder P., and Ornitz D.M. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell 64 (1991) 841-848