Spontaneous activation of the NF-κB signaling pathway in isolated normal glomeruli

American Journal of Physiology - Renal Physiology

Volumn 291, Issue 6, 2006, Pages

  Hayakawa, Kunihiro ^a   Meng, Yiman ^a,b   Hiramatsu, Nobuhiko ^a   Kasai, Ayumi ^a   Yao, Jian ^a   Kitamura, Masanori ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Isolated glomerulus; MAP kinase; Mesangial cell; TNF

Indexed keywords

ALKALINE PHOSPHATASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME RELEASE; ENZYME REPRESSION; GLOMERULUS; MALE; MESANGIUM CELL; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

EID: 33845357388     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00513.2005     Document Type: Article

References (38)

1. Baumbach L. Renin release from isolated rat glomeruli: effects of colchicine, vinca alkaloids, dimethylsulphoxide, and cytochalasins. J Physiol 299: 145-155, 1980.
2. Cattell V and Cook T. The nitric oxide pathway in glomerulonephritis. Curr Opin Nephrol Hypertens 4: 359-364, 1995.
3. Cohen MP and Vogt CA. Collagen synthesis and secretion by isolated rat renal glomeruli. Biochim Biophys Acta 393: 78-87, 1975.
4. Colasanti M and Persichini T. Nitric oxide: an inhibitor of NF-κB/Rel system in glial cells. Brain Res Bull 52: 155-161, 2000.
5. Dijkstra G, Moshage H, and Jansen PL. Blockade of NF-κB activation and donation of nitric oxide: new treatment options in inflammatory bowel disease? Scand J Gastroenterol Suppl 236: 37-41, 2002.
6. Fried TA, McCoy RN, Osgood RW, and Stein JH. Effect of atriopeptin II on determinants of glomerular filtration rate in the in vitro perfused dog glomerulus. Am J Physiol Renal Fluid Electrolyte Physiol 250: F1119-F1122, 1986.
7. Godfrin Y, Dantal J, Bouhours JF, Heslan JM, and Soulillou JP. A new method of measuring albumin permeability in isolated glomeruli. Kidney Int 50: 1352-1357, 1996.
8. Hiramatsu N, Kasai A, Meng Y, Hayakawa K, Yao J, and Kitamura M. Alkaline phosphatase vs. luciferase as secreted reporter molecules in vivo. Anal Biochem 339: 249-256, 2005.
9. Hruby ZW and Lowry RP. Spontaneous release of tumor necrosis factor-α by isolated renal glomeruli and cultured glomerular mesangial cells. Clin Immunol Immunopathol 59: 156-164, 1991.
10. Ishikawa Y and Kitamura M. Spontaneous apoptosis of podocytes in explanted glomeruli. Kidney Int 54: 2008-2013, 1998.
11. Ishikawa Y, Konta T, and Kitamura M. Spontaneous shift in the transcriptional profile of explanted glomeruli via activation of the MAP kinase family. Am J Physiol Renal Physiol 279: F954-F959, 2000.
12. Kasai A, Hiramatsu N, Meng Y, Yao J, Maeda S, and Kitamura M. Fast-track DRESSA: a bioassay for fast, sensitive, and selective detection of halogenated and polycyclic aromatic hydrocarbons. Anal Biochem 337: 84-88, 2005.
13. Kasai A, Hiramatsu N, Meng Y, Yao J, Takeda M, Maeda S, and Kitamura M. DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase. Anal Biochem 335: 73-80, 2004.
14. Kerr LD, Holt JT, and Matrisian LM. Growth factors regulate transin gene expression by c-fos-dependent and c-fos-independent pathways. Science 242: 1424-1427, 1988.
15. Kitamura M. Creation of a reversible on/off system for site-specific in vivo control of exogenous gene activity in the renal glomerulus. Proc Natl Acad Sci USA 93: 7387-7391, 1996.
16. Kitamura M. Identification of an inhibitor targeting macrophage production of monocyte chemoattractant protein-1 as TGF-β1. J Immunol 159: 1404-1411, 1997.
17. Kitamura M, Burton S, English J, Kawachi H, and Fine LG. Transfer of a mutated gene encoding active transforming growth factor-β1 suppresses mitogenesis and IL-1 response in the glomerulus. Kidney Int 48: 1747-1757, 1995.
18. Kitamura M, Taylor S, Unwin R, Burton S, Shimizu F, and Fine LG. Gene transfer into the rat renal glomerulus via a mesangial cell vector: site-specific delivery, in situ amplification, and sustained expression of an exogenous gene in vivo. J Clin Invest 94: 497-505, 1994.
19. Lee FS, Peters RT, Dang LC, and Maniatis T. MEKK1 activates both IκB kinase α and IκB kinase β. Proc Natl Acad Sci USA 95: 9319-9324, 1998.
20. Leitman DC, Ribeiro RC, Mackow ER, Baxter JD, and West BL. Identification of a tumor necrosis factor-responsive element in the tumor necrosis factor alpha gene. J Biol Chem 266: 9343-9346, 1991.
21. Li YS, Shyy JY, Li S, Lee J, Su B, Karin M, and Chien S. The Ras-JNK pathway is involved in shear-induced gene expression. Mol Cell Biol 16: 5947-5954, 1996.
22. Lucio-Cazana J, Nakayama K, Xu Q, Konta T, Moreno-Manzano V, Furusu A, and Kitamura M. Suppression of constitutive but not IL-1β-inducible expression of monocyte chemoattractant protein-1 in mesangial cells by retinoic acids: Intervention in the activator protein-1 pathway. J Am Soc Nephrol 12: 688-694, 2001.
23. Meng Y, Kasai A, Hiramatsu N, Hayakawa K, Takeda M, Shimizu F, Kawachi H, Yao J, and Kitamura M. Real-time monitoring of mesangial cell - macrophage cross-talk using SEAP in vitro and ex vivo. Kidney Int 68: 886-893, 2005.
24. Meng Y, Kasai A, Hiramatsu N, Hayakawa K, Yamauchi K, Takeda M, Kawachi H, Shimizu F, Yao J, and Kitamura M. Continuous, noninvasive monitoring of local microscopic inflammation using a genetically engineered cell-based biosensor. Lab Invest 85: 1429-1439, 2005.
25. Pennica D, Nedwin GE, Hayflick JS, Seeburg PH, Derynck R, Palladino MA, Kohr WJ, Aggarwal BB, and Goeddel DV. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature 312: 724-729, 1984.
26. Raij L and Baylis C. Glomerular actions of nitric oxide. Kidney Int 48: 20-32, 1995.
27. Rollins BJ, Morrison ED, and Stiles CD. Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc Natl Acad Sci USA 85: 3738-3742, 1988.
28. Savin VJ, Johnson RJ, and Couser WG. C5b-9 increases albumin permeability of isolated glomeruli in vitro. Kidney Int 46: 382-387, 1994.
29. Schlondorff D. Preparation and study of isolated glomeruli. Methods Enzymol 191: 130-140, 1990.
30. Schlondorff D, Roczniak S, Satriano JA, and Folkert VW. Prostaglandin synthesis by isolated rat glomeruli: effect of angiotensin II. Am J Physiol Renal Fluid Electrolyte Physiol 239: F486-F495, 1980.
31. Sedor JR and Abboud HE. Histamine modulates contraction and cyclic nucleotides in cultured rat mesangial cells. Differential effects mediated by histamine H1 and H2 receptors. J Clin Invest 75: 1679-1689, 1985.
32. Shyy YJ, Li YS, and Kolattukudy PE. Structure of human monocyte chemotactic protein gene and its regulation by TPA. Biochem Biophys Res Commun 169: 346-351, 1990.
33. Takashiba S, Shapira L, Amar S, and Van Dyke TE. Cloning and characterization of human TNF-α promoter region. Gene 131: 307-308, 1993.
34. Takeshita A, Chen Y, Watanabe A, Kitano S, and Hanazawa S. TGF-β induces expression of monocyte chemoattractant JE/monocyte chemoattractant protein 1 via transcriptional factor AP-1 induced by protein kinase in osteoblastic cells. J Immunol 155: 419-426, 1995.
35. Hayakawa K, Meng Y, Hiramatsu N, Kasai A, Yamauchi K, Yao J, and Kitamura M. Priming of glomerular mesangial cells by activated macrophages causes blunted responses to proinflammatory stimuli. J Immunol 176: 2529-2537, 2006.
36. Zhang Y, Hegen M, Xu J, Keith JC Jr, Jin G, Du X, Cummons T, Sheppard BJ, Sun L, Zhu Y, Rao VR, Wang Q, Xu W, Cowling R, Nickerson-Nutter CL, Gibbons J, Skotnicki J, Lin LL, and Levin J. Characterization of (2R, 3S)-2-([[4-(2- butynyloxy)phenyl]sulfonyl]amino)-N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-α converting enzyme. Int Immunopharmacol 4: 1845-1857, 2004.
37. Zhang Y, Xu J, Levin J, Hegen M, Li G, Robertshaw H, Brennan F, Cummons T, Clarke D, Vansell N, Nickerson-Nutter C, Barone D, Mohler K, Black R, Skotnicki J, Gibbons J, Feldmann M, Frost P, Larsen G, and Lin LL. Identification and characterization of 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N- hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a novel dual tumor necrosis factor-α-converting enzyme/matrix metalloprotease inhibitor for the treatment of rheumatoid arthritis. J Pharmacol Exp Ther 309: 348-355, 2004.
38. Zhao Q and Lee FS. Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-κB through IκB kinase-α and IκB kinase-β. J Biol Chem 274: 8355-8358, 1999.