Latrophilin-2 is a novel component of the epithelial-mesenchymal transition within the atrioventricular canal of the embryonic chicken heart

Developmental Dynamics

Volumn 235, Issue 12, 2006, Pages 3213-3221

  Doyle, Sally E ^a   Scholz, Matthew J ^a   Greer, Kevin A ^b   Hubbard, Antony D ^a   Darnell, Diana K ^a   Antin, Parker B ^a   Klewer, Scott E ^a   Runyan, Raymond B ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b University of Arizona   (United States)

Author keywords

Cardiac cushions; Cardiac development; EMT; Microarray; Pertussis toxin; TGF beta; Valvulosepatal development

Indexed keywords

CELL PROTEIN; COLLAGEN GEL; COMPLEMENTARY DNA; G PROTEIN COUPLED RECEPTOR; LATROPHILIN 2; PERTUSSIS TOXIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL TISSUE; ATRIOVENTRICULAR CANAL; CHICKEN; EMBRYO; ENDOTHELIUM; EPITHELIUM CELL; EXPRESSED SEQUENCE TAG; GASTRULATION; GENE; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; HEART DEVELOPMENT; HEART MUSCLE; LATROPHILIN 2 GENE; MESENCHYME CELL; MICROARRAY ANALYSIS; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; CHICK EMBRYO; DNA, ANTISENSE; EPITHELIUM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; IN SITU HYBRIDIZATION; MESODERM; MYOCARDIUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PERTUSSIS TOXIN; RECEPTORS, PEPTIDE; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 33845356457     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.20973     Document Type: Review

References (33)

1. Azhar M, Schultz JEJ, Grupp I, Dorn GW, Meneton P, Molin DGM, Gittenberger-de Groot AC, Doetschman T. 2003. Transforming growth factor beta in cardiovascular development and function. Cytok Growth Fact Rev 14:391-407.
2. Bakin AV, Rinehart C, Tomlinson AK, Arteaga CL. 2002. p38 mitogen-activated protein kinase is required for TGF beta-mediated fibroblastic transdifferentiation and cell migration. J Cell Sci 115:3193-3206.
3. Bell GW, Yatskievych TA, Antin PB. 2004. GEISHA, a gallus EST in situ hybridization approach to large scale gene discovery. Dev Dyn 229:677-687.
4. Boyer AS, Ayerinskas II, Vincent EB, McKinney LA, Weeks DL, Runyan RB. 1999a. TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart. Dev Biol 208:530-545.
5. Boyer AS, Erikson CP, Runyan RB. 1999b. Epithelial-mesenchymal transformation in the embryonic heart is mediated through distinct pertussis toxin-sensitive and TGFβ signal transduction mechanisms. Dev Dyn 214:81-91.
6. Brown CB, Boyer AS, Runyan RB, Barnett JV. 1996. Antibodies to the TGFβ type II receptor perturb both epithelial-mesenchymal cell transformation and cell migration by embryonic heart mesenchyme. Dev Biol 174:248-257.
7. Brown CB, Boyer AS, Runyan RB, Barnett JV. 1999. Requirement of the type III TGFβ receptor for endocardial cell transformation in the heart. Science 283:2080-2082.
8. Camenisch TD, Molin DGM, Person A, Runyan RB, Gittenberger-De Groot AC, McDonald JA, Klewer SE 2002. Temporal and distinct TGF beta ligand requirements during mouse and avian endocardial cushion morphogenesis. Dev Biol 248:170-181.
9. Dolmetsch RE, Xu KL, Lewis RS. 1998. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392:933-936.
10. Draghici S, Khatri P, Eklund AC, Szallasi Z. 2006. Reliability and reproducibility issues in DNA microarray measurements. Trends Genet 22:101-109.
11. Greer KA, McReynolds MR, Brooks HL, Hoying JB. 2006. CARMA: A platform for analyzing microarray datasets that incorporate replicate measures. BMC Bioinformatics 17:149.
12. Hamburger V, Hamilton HL. 1951. A series of normal stages in the development of the chick embryo. J Morphol 88:49-92.
13. Hlubek M, Tian D, Stuenkel EL. 2003. Mechanism of a-latrotoxin action at nerve endings of neurohypophysis. Brain Res 992:30-42.
14. Kerr MK, Churchill GA. 2001. Statistical design and the analysis of gene expression microarray data. Genet Res 77:123-128.
15. Matsushita H, Lelianova VG, Ushkaryov YA. 1999. The latrophilin family: multiply spliced G protein-coupled receptors with differential tissue distribution. FEBS Lett 443:348-352.
16. Nakajima Y, Yamagishi T, Hokari S, Nakamura H. 2000. Mechanism involved in valvuloseptal endocardial cushion formation in early cardiogenesis: Roles of and bone morphogenetic protein [symbol: Arial/63]Transforming growth factor beta (TGF-b (BMP). Anat Rec 258:119-127.
17. Nakaya Y, Kuroda S, Katagiri YT, Kaibuchi K, Takahashi Y. 2004. Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1. Dev Cell 7:425-438.
18. Nieto MA, Patel K, Wilkinson DG. 1996. In situ hybridization analysis of chick embryos in whole mount and tissue sections. Methods Cell Biol 51:219-235.
19. Person TD, Garriock RJ, Kreig PA, Runyan RB, Klewer SE. 2005a. Frzb modulates Wnt-9a mediated beta-catenin signaling during avian atrioventricular cardiac cushion development. Dev Biol 278:35-48
20. Person AD, Klewer SE, Runyan RB. 2005b. Cell biology of cardiac cushion development. Int Rev Cytol 243:287-335.
21. Potts JD, Dagle JM, Walder JA, Weeks DL, Runyan RB. 1991. Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified antisense oligodeoxynucleotide to transforming growth factor beta 3. Proc Natl Acad Sci USA 88:1516-1520.
22. Potts JD, Runyan RB. 1989. Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor beta. Dev Biol 134:392-401.
23. Potts JD, Vincent EB, Runyan RB, Weeks DL. 1992. Sense and antisense TGFβ3 mRNAs correlate with valve induction in the heart. Dev Dyn 193:340-345.
24. Romano LA, Runyan RB. 1999. Slug is a mediator of epithelial-mesenchymal transformation in the developing chicken heart. Dev Biol 212:243-254.
25. Runyan RB, Markwald RR. 1983. Invasion of mesenchyme into three-dimensional collagen gels: A regional and temporal analysis of interaction in embryonic heart tissue. Dev Biol 95:108-114.
26. Runyan RB, Potts JD, Sharma RV, Loeber CP, Chiang JJ, Bhalla RC. 1990. Signal transduction of a tissue interaction during embryonic heart development. Cell Regul 1:301-313.
27. Runyan RB, Potts JD, Weeks DL 1992. TGF-beta 3-mediated tissue interaction during embryonic heart development. Mol Reprod Dev 32:152-159.
28. Runyan RB, Wendler CC, Romano LA, Boyer AS, Dagle JM Weeks, DL. 1999. Utilization of antisense oligodeoxynucleotides with embryonic tissues in culture. Methods 18:316-321.
29. Tang GL. 2005. siRNA and miRNA: an insight into RISCs. Trends Biochem Sci 30:106-114.
30. White GRM, Varley JM, Heighway J. 1998. Isolation and characterization of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer. Oncogene 17:3513-3519.
31. Wrana JL, Attisano, L. 2000. The Smad pathway. Cytok Growth Fact Rev 11:5-13.
32. Xie L, Law BK, Aakre ME, Edgerton M, Shyr Y, Bhowmick NA, Moses HL. 2003. Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res 5:R187-R198.
33. Zhao XS, Shin DM, Liu LH, Shull GE, Muallem S. 2001. Plasticity and adaptation of Ca2+ signaling and Ca2+-dependent exocytosis in SERCA2 (±) mice. EMBO J 20:2680-2689.