Measuring liability for schizophrenia using optimized antisaccade stimulus parameters

Psychophysiology

Volumn 36, Issue 1, 1999, Pages 138-141

  McDowell, Jennifer E ^a,b   Myles Worsley, Marina ^c   Coon, Hilary ^c   Byerley, William ^c   Clementz, Brett A ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d NONE   (United States)

Author keywords

Antisaccades; Dorsolateral prefrontal cortex; Family study; Genetics; Saccades; Schizophrenia

Indexed keywords

ARTICLE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FAMILY HISTORY; GENETIC PREDISPOSITION; HUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; SCHIZOPHRENIA;

EID: 0032899942     PISSN: 00485772     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0048577299980836     Document Type: Article

References (16)

1. Arolt, V., Lencer, R., Nolte, A., Muller-Myhsok, B., Purmann, S., Schurmann, M., Leutelt, J., Pinnow, M., & Schwinger, E. (1996). Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease. American Journal of Medical Genetics, 67, 564-579.
2. Clementz, B. A. (in press). Psychophysiological measures of (dis)inhibition as liability indicators for schizophrenia. Psychophysiology.
3. Clementz, B. A., McDowell, J. E., & Zisook, S. (1994). Saccadic system functioning among schizophrenia patients and their first-degree biological relatives. Journal of Abnormal Psychology, 103, 277-287.
4. Coon, H., Plaetke, R., Holik, J., Hoff, M., Myles-Worsley, M., Waldo, M. C., Freedman, R., Byerley, W. (1993). Use of a neurophysiological trait in the linkage analysis of schizophrenia. Biological Psychiatry, 34, 277-289.
5. Crawford, T. J., Puri, B. K., Nijran, K. S., Jones, B., Kennard, C., & Lewis, S. W. (1996). Abnormal saccadic distractibility in patients with schizophrenia: A 99mTc-HMPAO SPET study. Psychological Medicine, 26, 265-277.
6. Fukushima, J., Morita, N., Fukushima, K., Chiba, T., Tanaka, S., & Yamashita, I. (1990). Voluntary control of saccadic eye movements in patients with schizophrenic and affective disorders. Journal of Psychiatric Research, 24, 9-24.
7. Grove, W. M., Clementz, B. A., Iacono, W. G., & Katsanis, J. (1992). Smooth pursuit ocular motor dysfunction in schizophrenia: Evidence for a major gene. American Journal of Psychiatry, 149, 1362-1368.
8. Holzman, P. S., Kringlen, E., Matthysse, S., Flanagan, S. D., Lipton, R. B., Cramer, G., Levin, S., Lange, K., & Levy, D. L. (1988). A single dominant gene can account for eye tracking dysfunctions and schizophrenia in offspring of discordant twins. Archives of General Psychiatry, 45, 641-647.
9. Iacono, W. G., & Clementz, B. A. (1993). A strategy for elucidating genetic influences on complex psychopathological syndromes (with special reference to ocular motor functioning and schizophrenia). Progress in Experimental Personality and Psychopathology Research, 16, 11-65.
10. Katsanis, J., Kortenkamp, S., Iacono, W. G., & Grove, W. M. (1997). Antisaccade performance in patients with schizophrenia and affective disorder. Journal of Abnormal Psychology, 106, 468-472.
11. Lander, E. S., & Schork, N. J. (1994). Genetic dissection of complex traits. Science, 265, 2037.
12. McDowell, J. E., & Clementz, B. A. (1997). The effect of fixation condition manipulations on antisaccade performance in schizophrenia. Experimental Brain Research, 115, 333-344.
13. Myles-Worsley, M., Coon, H., Tiobech, J., Collier, J., Dale, P., Wender, P., Reimherr, F., Polloi, A., & Byerley, W. (in press). A genetic epidemiological study of schizophrenia in Palau, Micronesia I. Prevalence and familiality. American Journal of Medical Genetics: Neuropsychiatric Genetics.
14. Pierrot-Deseilligny, C. (1994). Saccade and smooth-pursuit impairment after cerebral hemispheric lesions. European Neurology, 34, 121-134.
15. Risch, N. (1990). Genetic linkage and complex diseases, with special reference to psychiatric disorders. Genetic Epidemiology, 7, 3-16.
16. Weinberger, D. R., Aloia, M. S., Goldberg, T. E., & Berman, K. F. (1994). The frontal lobes and schizophrenia. Journal of Neuropsychiatry Clinical Neuroscience, 6, 419-427.