Critical illness and mechanical ventilation: Effects on the diaphragm

Respiratory Care

Volumn 51, Issue 9, 2006, Pages 1054-1061

  Jubran, Amal ^a,b  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b HINES VA HOSPITAL   (United States)

Author keywords

Acute respiratory failure; Atrophy; Barotrauma; Cardiovascular; Complications; Diaphragm; Fiber remodeling; Lung injury; Mechanical ventilation; Oxidative stress; Pneumonia; Ventilator; Weakness

Indexed keywords

NEUROMUSCULAR BLOCKING AGENT;

ACUTE RESPIRATORY FAILURE; ARTIFICIAL VENTILATION; ATROPHY; BAROTRAUMA; BREATHING MUSCLE; CARDIOVASCULAR DISEASE; CONFERENCE PAPER; CRITICAL ILLNESS; DIAPHRAGM; DIAPHRAGM INJURY; HUMAN; LUNG INJURY; MUSCLE CONTRACTILITY; MUSCLE WEAKNESS; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PNEUMONIA; VENTILATOR; WEANING;

CRITICAL ILLNESS; DIAPHRAGM; HUMANS; LUNG; RESPIRATION, ARTIFICIAL; RESPIRATORY INSUFFICIENCY; VENTILATORS, MECHANICAL;

EID: 33845292563     PISSN: 00201324     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (47)

1. Tobin MJ. Advances in mechanical ventilation. N Engl J Med 2001; 344(26):1986-1996.
2. Dreyfuss D, Saumon G. Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 1998;157(1):294-323.
3. Vassilakopoulos T, Petrof BJ. Ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med 2004;169(3):336-341.
4. Webb HH, Tierney DF. Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures: protection by positive end-expiratory pressure. Am Rev Respir Dis 1974;110(5):556-565.
5. Hickling KG, Henderson SJ, Jackson R. Low mortality associated with low volume pressure limited ventilation with permissive hypercapnia in severe adult respiratory distress syndrome. Intensive Care Med 1990;16(6):372-377.
6. Amato MBP, Barbas CSV, Medeiros DM, Schettino GdeP, Lorenzi Filho G, Kairalla RA, et al. Beneficial effects of the "open lung approach" with low distending pressures in acute respiratory distress syndrome: a prospective randomized study on mechanical ventilation. Am J Respir Crit Care Med 1995;152(6 Pt 1):1835-1846.
7. Amato MB, Barbas CS, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi-Filho G, et al. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998;338(6):347-354.
8. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000;342(18):1301- 1308.
9. Tobin MJ. Culmination of an era in research on the acute respiratory distress syndrome (editorial). N Engl J Med 2000;342(18):1360-1361.
10. Eichacker PQ, Gerstenberger EP, Banks SM, Cui X, Natanson C. Meta-analysis of acute lung injury and acute respiratory distress syndrome trials testing low tidal volumes. Am J Respir Crit Care Med 2002;166(11):1510- 1514.
11. Kallet RH, Jasmer RM, Pittet JF, Tang JF, Campbell AR, Dicker R, et al. Clinical implementation of the ARDS network protocol is associated with reduced hospital mortality compared with historical controls. Crit Care Med 2005;33(5):925-929.
12. Deans KJ, Minneci PC, Cui X, Banks SM, Natanson C, Eichacker PQ. Mechanical ventilation in ARDS: one size does not fit all (editorial). Crit Care Med 2005;33(5):1141-1143.
13. Anzueto A, Peters JI, Tobin MJ, de los Santos R, Seidenfeld JJ, Moore G, et al. Effects of prolonged controlled mechanical ventilation on diaphragmatic function in healthy adult baboons. Crit Care Med 1997;25(7):1187-1190.
14. Radell PJ, Remahl S, Nichols DG, Eriksson LI. Effects of prolonged mechanical ventilation and inactivity on piglet diaphragm function. Intensive Care Med 2002;28(3):358-364.
15. Sassoon CS, Caiozzo VJ, Manka A, Sieck GC. Altered diaphragm contractile properties with controlled mechanical ventilation. J Appl Physiol 2002;92(6):2585-2595.
16. Le Bourdelles G, Viires N, Boczkowski J, Seta N, Pavlovic D, Aubier M. Effects of mechanical ventilation on diaphragmatic contractile properties in rats. Am J Respir Crit Care Med 1994;149(6):1539-1544.
17. Powers SK, Shanely RA, Coombes JS, Koesterer TJ, McKenzie M, Van Gammeren D, et al. Mechanical ventilation results in progressive contractile dysfunction in the diaphragm. J Appl Physiol 2002; 92(5):1851-1858.
18. Laghi F, Tobin MJ. Disorders of the respiratory muscles. Am J Respir Crit Care Med 2003;168(1):10-48.
19. Cattapan SE, Laghi F, Tobin MJ. Can diaphragmatic contractility be assessed by airway twitch pressure in mechanically ventilated patients? Thorax 2003;58(1):58-62.
20. Watson AC, Hughes PD, Louise Harris M, Hart N, Ware RJ, Wendon J, et al. Measurement of twitch transdiaphragmatic, esophageal, and endotracheal tube pressure with bilateral anterolateral magnetic phrenic nerve stimulation in patients in the intensive care unit. Crit Care Med 2001;29(7):1325-1331.
21. Laghi F. Assessment of respiratory output in mechanically ventilated patients. Respir Care Clin N Am 2005;11(2):173-199.
22. Yang L, Luo J, Bourdon J, Lin MC, Gottfried SB, Petrof BJ. Controlled mechanical ventilation leads to remodeling of the rat diaphragm. Am J Respir Crit Care Med 2002;166(8):1135-1140.
23. Shanely RA, Zergeroglu MA, Lennon SL, Sugiura T, Yimlamai T, Enns D, et al. Mechanical ventilation-induced diaphragmatic atrophy is associated with oxidative injury and increased proteolytic activity. Am J Respir Crit Care Med 2002;166(10):1369-1374.
24. Capdevila X, Lopez S, Bernard N, Rabischong E, Ramonatxo M, Martinazzo G, Prefaut C. Effects of controlled mechanical ventilation on respiratory muscle contractile properties in rabbits. Intensive Care Med 2003;29(1):103-110.
25. Knisely AS, Leal SM, Singer DB. Abnormalities of diaphragmatic muscle in neonates with ventilated lungs. J Pediatr 1988;113(6):1074-1077.
26. Hussain SN, Vassilakopoulos T. Ventilator-induced cachexia (editorial). Am J Respir Crit Care Med 2002;166(10):1307-1308.
27. Shanely RA, Van Gammeren D, Deruisseau KC, Zergeroglu AM, McKenzie MJ, Yarasheski KE, Powers SK. Mechanical ventilation depresses protein synthesis in the rat diaphragm. Am J Respir Crit Care Med 2004;170(9):994-999.
28. Geiger PC, Cody MJ, Macken RL, Sieck GC. Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers. J Appl Physiol 2000;89(2):695-703.
29. Vassilakopoulos T. Ventilator-induced diaphragm dysfunction. In: Tobin MJ, editor. Principles and practice of mechanical ventilation. New York: McGraw-Hill; 2006.
30. Zergeroglu MA, McKenzie MJ, Shanely RA, Van Gammeren D, DeRuisseau KC, Powers SK. Mechanical ventilation-induced oxidative stress in the diaphragm. J Appl Physiol 2003;95(3):1116-1124.
31. Kondo H, Nakagaki I, Sasaki S, Hori S, Itokawa Y. Mechanism of oxidative stress in skeletal muscle atrophied by immobilization. Am J Physiol 1993;265(6 Pt 1):E839-E844.
32. Li YP, Chen Y, Li AS, Reid MB. Hydrogen peroxide stimulates ubiquitin-conjugating activity and expression of genes for specific E2 and E3 proteins in skeletal muscle myotubes. Am J Physiol Cell Physiol 2003;285(4):C806-C812.
33. Reid MB. Invited Review: redox modulation of skeletal muscle contraction: what we know and what we don't. J Appl Physiol 2001; 90(2):724-731.
34. Betters JL, Criswell DS, Shanely RA, Van Gammeren D, Falk D, Deruisseau KC, et al. Trolox attenuates mechanical ventilation-induced diaphragmatic dysfunction and proteolysis. Am J Respir Crit Care Med 2004;170(11):1179-1184.
35. Nathens AB, Neff MJ, Jurkovich GJ, Klotz P, Farver K, Ruzinski JT, et al. Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg 2002;236(6):814-822.
36. Bernard N, Matecki S, Py G, Lopez S, Mercier J, Capdevila X. Effects of prolonged mechanical ventilation on respiratory muscle ultrastructure and mitochondrial respiration in rabbits. Intensive Care Med 2003;29(1):111-118.
37. Sassoon CS, Zhu E, Caiozzo VJ. Assist-control mechanical ventilation attenuates ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med 2004;170(6):626-632.
38. Esteban A, Anzueto A, Alia I, Gordo F, Apezteguia C, Palizas F, et al. How is mechanical ventilation employed in the intensive care unit? An international utilization review. Am J Respir Crit Care Med 2000;161(5):1450- 1458.
39. Tobin MJ, Jubran A. Weaning from mechanical ventilation. In: Tobin MJ, editor. Principles and practice of mechanical ventilation, 2nd ed. New York: McGraw-Hill; 2006.
40. Jubran A, Tobin MJ. Pathophysiologic basis of acute respiratory distress in patients who fail a trial of weaning from mechanical ventilation. Am J Respir Crit Care Med 1997;155(3):906-915.
41. Tobin MJ, Perez W, Guenther SM, Semmes BJ, Mador MJ, Allen SJ, et al. The pattern of breathing during successful and unsuccessful trials of weaning from mechanical ventilation. Am Rev Respir Dis 1986;134(6):1111-1118.
42. Lemaire F, Teboul JL, Cinotti L, Giotto G, Abrouk F, Steg G, et al. Acute left ventricular dysfunction during unsuccessful weaning from mechanical ventilation. Anesthesiology 1988;69(2):171-179.
43. Jubran A, Mathru M, Dries D, Tobin MJ. Continuous recordings of mixed venous oxygen saturation during weaning from mechanical ventilation and the ramifications thereof. Am J Respir Crit Care Med 1998;158(6):1763-1769.
44. Laghi F, Cattapan SE, Jubran A, Parthasarathy S, Warshawsky P, Choi YS, Tobin MJ. Is weaning failure caused by low-frequency fatigue of the diaphragm? Am J Respir Crit Care Med 2003;167(2): 120-127.
45. Laghi F, D'Alfonso N, Tobin MJ. Pattern of recovery from diaphragmatic fatigue over 24 hours. J Appl Physiol 1995;79(2):539-546.
46. Bellemare F, Grassino A. Effect of pressure and timing of contraction on human diaphragm fatigue. J Appl Physiol 1982;53(5):1190-1195.
47. Laghi F, Jubran A, Topeli A, Fahey PJ, Garrity ER, Arcidi JM, et al. Effect of lung volume reduction surgery on neuromechanical coupling of the diaphragm. Am J Respir Crit Care Med 1998;157(2):475-483.