Controlled mechanical ventilation leads to remodeling of the rat diaphragm

American Journal of Respiratory and Critical Care Medicine

Volumn 166, Issue 8, 2002, Pages 1135-1140

  Yang, Liying ^a,b   Luo, Jun ^a,b   Bourdon, Johanne ^a,b   Lin, Meng Chi ^a,b   Gottfried, Stewart B ^a,b   Petrof, Basil J ^a,b,c  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Diaphragm disuse; Hybrid fibers; Myosin heavy chain isoforms; Respiratory muscles; Weaning

Indexed keywords

CONTRACTILE PROTEIN; ISOPROTEIN; MYOSIN HEAVY CHAIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BODY WEIGHT; CONTROLLED STUDY; DIAPHRAGM; DIAPHRAGM MUSCLE; FORCE; HYBRID; MALE; MUSCLE MASS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WEANING; ANIMAL; HINDLIMB; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; METABOLISM; MUSCLE CELL; MUSCLE CONTRACTION; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; SKELETAL MUSCLE; SPRAGUE DAWLEY RAT;

ANIMALS; BODY WEIGHT; DIAPHRAGM; HINDLIMB; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE CONTRACTION; MUSCLE FIBERS; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL;

EID: 0037108633     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.2202020     Document Type: Article

References (39)

1. Esteban A, Anzueto A, Frutos F, Alia I, Brochard L, Stewart TE, Benito S, Epstein SK, Apezteguia C, Nightingale P, et al. Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. JAMA 2002;287:345-355.
2. Vassilakopoulos T, Zakynthinos S, Roussos C. Respiratory muscles and weaning failure. Eur Respir J 1996;9:2383-2400.
3. MacIntyre NR. Ventilatory muscles and mechanical ventilatory support. Crit Care Med 1997;25:1106-1107.
4. Tobin MJ, Jubran A, Laghi F. Patient-ventilator interaction. Am J Respir Crit Care Med 2001;163:1059-1063.
5. Tobin MJ, Laghi F, Jubran A. Respiratory muscle dysfunction in mechanically-ventilated patients. Mol Cell Biochem 1998;179:87-98.
6. Anzueto A, Peters JI, Tobin MJ, De Los Santos R, Seidenfeld JJ, Moore G, Cox WJ, Coalson JJ. Effects of prolonged controlled mechanical ventilation on diaphragmatic function in healthy adult baboons. Crit Care Med 1997;25:1187-1190.
7. Le Bourdelles G, Viires N, Boczkowski J, Seta N, Pavlovic D, Aubier M. Effects of mechanical ventilation on diaphragmatic contractile properties in rats. Am J Respir Crit Care Med 1994;149:1539-1544.
8. Powers SK, Shanely A, Coombes JS, Koesterer TJ, McKenzie M, Van Gammeren D, Cicale M, Dodd SL. Mechanical ventilation results in progressive contractile dysfunction in the diaphragm. J Appl Physiol 2002;92:1851-1858.
9. Radell PJ, Remahl S, Nichols DG, Eriksson LI. Effects of prolonged mechanical ventilation and inactivity on piglet diaphragm function. Intensive Care Med 2002;28:358-364.
10. Loughna PT, Izumo S, Goldspink G, Nadal-Ginard B. Disuse and passive stretch cause rapid alterations in expression of developmental and adult contractile protein genes in skeletal muscle. Development 1990;109:217-223.
11. Huey KA, Roy RR, Baldwin KM, Edgerton VR. Temporal effects of inactivity on myosin heavy chain gene expression in rat slow muscle. Muscle Nerve 2001;24:517-526.
12. Allen DL, Yasui W, Tanaka T, Ohira Y, Nagaoka S, Sekiguchi C, Hinds WE, Roy RR, Edgerton VR. Myonuclear number and myosin heavy chain expression in rat soleus single muscle fibers after spaceflight. J Appl Physiol 1996;81:145-151.
13. Michel RN, Parry DJ, Dunn SE. Regulation of myosin heavy chain expression in adult rat hindlimb muscles during short-term paralysis: comparison of denervation and tetrodotoxin-induced neural inactivation. FEBS Lett 1996;391:39-44.
14. Caiozzo VJ, Haddad F, Baker MJ, Herrick RE, Prietto N, Baldwin KM. Microgravity-induced transformation of myosin isoforms and contractile properties of skeletal muscle. J Appl Physiol 1996;81:123-132.
15. Talmadge RJ. Myosin heavy chain isoform expression following reduced neuromuscular activity: potential regulatory mechanisms. Muscle Nerve 2000;23:661-679.
16. Zhan W-Z, Miyata H, Prakash YS, Sieck GC. Metabolic and phenotypic adaptations of diaphragm muscle fibers with inactivation. J Appl Physiol 1997;82:1145-1153.
17. Yang L, Bourdon J, Gottfried SB, Zin WA, Petrof BJ. Regulation of myosin heavy chain gene expression after short-term diaphragm inactivation. Am J Physiol 1998;274:L980-L989.
18. Newman S, Road J, Bellemare F, Clozel JP, Lavigne CM, Grassino A. Respiratory muscle length measured by sonomicrometry. J Appl Physiol 1984;56:753-764.
19. Petrof BJ, Kimoff RJ, Levy RD, Cosio MG, Gottfried SB. Nasal continuous positive airway pressure facilitates respiratory muscle function during sleep in severe chronic obstructive pulmonary disease. Am Rev Respir Dis 1991;143:928-935.
20. DiMario JX, Fernyak SE, Stockdale FE. Myoblasts transferred to the limbs of embryos are committed to specific fibre fates. Nature 1993;362:165-167.
21. Pette D, Staron RS. Myosin isoforms, muscle fiber types, and transitions. Microsc Res Tech 2000;50:500-509.
22. Reiser PJ, Moss RL, Giulian GG, Greaser ML. Shortening velocity in single fibers from adult rabbit soleus muscles is correlated with myosin heavy chain composition. J Biol Chem 1985;260:9077-9080.
23. Reiser PJ, Kasper CE, Greaser ML, Moss RL. Functional significance of myosin transitions in single fibers of developing soleus muscle. Am J Physiol 1988;254:C605-C613.
24. Eddinger TJ, Moss RL. Mechanical properties of skinned single fibers of identified types from rat diaphragm. Am J Physiol 1987;253:C210-C218.
25. Geiger PC, Cody MJ, Macken RL, Sieck GC. Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers. J Appl Physiol 2000;89:695-703.
26. Jiang B, Roy RR, Navarro C, Edgerton VR. Absence of a growth hormone effect on rat soleus atrophy during a 4-day spaceflight. J Appl Physiol 1993;74:527-531.
27. Lewis MI, Sieck GC, Fournier M, Belman MJ. Effect of nutritional deprivation on diaphragm contractility and muscle fiber size. J Appl Physiol 1986;60:596-603.
28. Kelsen SG, Ference M, Kapoor S. Effects of prolonged undernutrition on structure and function of the diaphragm. J Appl Physiol 1985;58:1354-1359.
29. Lewis MI, LoRusso TJ, Zhan W-Z, Sieck GC. Interactive effects of denervation and malnutrition on diaphragm structure and function. J Appl Physiol 1996;81:2165-2172.
30. Lanz JK, Donahoe M, Rogers RM, Ontell M. Effects of growth hormone on diaphragmatic recovery from malnutrition. J Appl Physiol 1992;73:801-805.
31. Riley DA, Ellis S, Giometti CS, Hoh JFY, Ilyina-Kakueva EI, Oganov VS, Slocum GR, Bain JLW, Sedlak FR. Muscle sarcomere lesions and thrombosis after spaceflight and suspension unloading. J Appl Physiol 1992;73:33S-43S.
32. Hogue CW Jr, Ward JM, Itani MS, Martyn JA. Tolerance and upregulation of acetylcholine receptors follow chronic infusion of d-tubocurarine. J Appl Physiol 1992;72:1326-1331.
33. Gosselin LE, Brice G, Carlson B, Prakash YS, Sieck GC. Changes in satellite cell mitotic activity during acute period of unilateral diaphragm denervation. J Appl Physiol 1994;77:1128-1134.
34. Rome LC, Funke RP, Alexander RM, Lutz G, Aldridge H, Scott F, Freadman M. Why animals have different muscle fibre types. Nature 1988;335:824-827.
35. Riley DA, Slocum GR, Bain JLW, Sedlak FR, Sowa TE, Mellender JW. Rat hindlimb unloading: soleus histochemistry, ultrastructure, and electromyography. J Appl Physiol 1990;69:58-66.
36. Danon MJ. Carpenter S. Myopathy with thick filament (myosin) loss following prolonged paralysis with vecuronium during steroid treatment. Muscle Nerve 1991;14:1131-1139.
37. Supinski GS, Kelsen SG. Effect of elastase-induced emphysema on the force-generating ability of the diaphragm. J Clin Invest 1982;70:978-988.
38. Farkas GA, Roussos C. Diaphragm in emphysematous hamsters: sarcomere adaptability. J Appl Physiol 1983;54:1635-1640.
39. Maltais F, Reissmann H, Navalesi P, Hernandez P, Gursahaney A, Ranieri VM, Sovilj M, Gottfried SB, Comparison of static and dynamic measurements of intrinsic PEEP in mechanically ventilated patients. Am J Respir Crit Care Med 1994;150:1318-1324.