Environmental discontinuity hypothesis: Buffer dysfunctions as a source of human disease

Medical Hypotheses

Volumn 68, Issue 2, 2007, Pages 434-438

  Yun, Anthony J ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MELATONIN; SUNSCREEN; VITAMIN D;

ACUTE CORONARY SYNDROME; ALTITUDE ACCLIMATIZATION; ARTICLE; ATMOSPHERIC PRESSURE; AUTONOMIC DYSFUNCTION; AVIATION; DISEASE ASSOCIATION; DISEASE COURSE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL TEMPERATURE; EVOLUTIONARY ADAPTATION; HEART FAILURE; HUMAN; HYPOTHESIS; LIFESTYLE; MELANOMA; OXYGEN TENSION; PRIORITY JOURNAL; SKIN CANCER; SKIN PIGMENTATION; SUN EXPOSURE; SUNLIGHT; TEMPERATURE; TEMPERATURE ACCLIMATIZATION; VENOUS THROMBOEMBOLISM; VIRUS INFECTION;

ADAPTATION, PHYSIOLOGICAL; ALTITUDE; DISEASE; ENVIRONMENT; HUMANS;

EID: 33845289232     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2005.11.049     Document Type: Article

References (56)

1. Cleaver J.E., and Crowley E. UV damage, DNA repair and skin carcinogenesis. Front Biosci 7 (2002) 1024-1043
2. Whiteman D.C., Watt P., Purdie D.M., Hughes M.C., Hayward N.K., and Green A.C. Melanocytic nevi, solar keratoses, and divergent pathways to cutaneous melanoma. J Natl Cancer Inst 95 11 (2003) 806-812
3. Gallagher R.P., Rivers J.K., Lee T.K., Bajdik C.D., McLean D.I., and Coldman A.J. Broad-spectrum sunscreen use and the development of new nevi in white children: a randomized controlled trial. JAMA 283 22 (2000) 2955-2960
4. Desmond R.A., and Soong S.J. Epidemiology of malignant melanoma. Surg Clin North Am 83 1 (2003) 1-29
5. Beddingfield III F.C. The melanoma epidemic: res ipsa loquitur. Oncologist 8 5 (2003) 459-465
6. Pappo A.S. Melanoma in children and adolescents. Eur J Cancer 39 18 (2003) 2651-2661
7. McCarthy W.H. The Australian experience in sun protection and screening for melanoma. J Surg Oncol 86 4 (2004) 236-245
8. Oikarinen A., and Raitio A. Melanoma and other skin cancers in circumpolar areas. Int J Circumpolar Health 59 1 (2000) 52-56
9. Westerdahl J., Olsson H., Masback A., Ingvar C., and Jonsson N. Is the use of sunscreens a risk factor for malignant melanoma?. Melanoma Res 5 1 (1995) 59-65
10. Westerdahl J., Ingvar C., Masback A., and Olsson H. Sunscreen use and malignant melanoma. Int J Cancer 87 1 (2000) 145-150
11. Autier P., Dore J.F., Negrier S., Lienard D., Panizzon R., Lejeune F.J., et al. Sunscreen use and duration of sun exposure: a double-blind, randomized trial. J Natl Cancer Inst 91 15 (1999) 1304-1309
12. Bastuji-Garin S., and Diepgen T.L. Cutaneous malignant melanoma, sun exposure, and sunscreen use: epidemiological evidence. Br J Dermatol 146 Suppl. 61 (2002) 24-30
13. Dennis L.K., Beane Freeman L.E., and VanBeek M.J. Sunscreen use and the risk for melanoma: a quantitative review. Ann Intern Med 139 12 (2003) 966-978
14. Bigby M.E. The end of the sunscreen and melanoma controversy?. Arch Dermatol 140 6 (2004) 745-746
15. Weisberg P., Scanlon K.S., Li R., and Cogswell M.E. Nutritional rickets among children in the United States: review of cases reported between 1986 and 2003. Am J Clin Nutr 80 6 Suppl. (2004) 1697S-1705S
16. Armstrong B.K., and Kricker A. How much melanoma is caused by sun exposure?. Melanoma Res 3 6 (1993) 395-401
17. Stokstad E. Nutrition. The vitamin D deficit. Science 302 5652 (2003) 1886-1888
18. Isaia G., Giorgino R., Rini G.B., Bevilacqua M., Maugeri D., and Adami S. Prevalence of hypovitaminosis D in elderly women in Italy: clinical consequences and risk factors. Osteoporos Int 14 7 (2003) 577-582
19. Gessner B.D., Plotnik J., and Muth P.T. 25-Hydroxyvitamin D levels among healthy children in Alaska. J Pediatr 143 4 (2003) 434-437
20. Berwick M., Armstrong B.K., Ben-Porat L., Fine J., Kricker A., Eberle C., et al. Sun exposure and mortality from melanoma. J Natl Cancer Inst 97 3 (2005) 195-199
21. Egan K.M., Sosman J.A., and Blot W.J. Sunlight and reduced risk of cancer: is the real story vitamin D?. J Natl Cancer Inst 97 3 (2005) 161-163
22. Osborne J.E., and Hutchinson P.E. Vitamin D and systemic cancer: is this relevant to malignant melanoma?. Br J Dermatol 147 2 (2002) 197-213
23. Moon S.J., Fryer A.A., and Strange R.C. Ultraviolet radiation: effects on risks of prostate cancer and other internal cancers. Mutat Res 571 1-2 (2005) 207-219
24. Cantorna M.T., and Mahon B.D. Mounting evidence for vitamin D as an environmental factor affecting autoimmune disease prevalence. Exp Biol Med 229 11 (2004) 1136-1142
25. Colston K., Colston M.J., and Feldman D. 1,25-Dihydroxyvitamin D3 and malignant melanoma: the presence of receptors and inhibition of cell growth in culture. Endocrinology 108 (1981) 1083-1086
26. Sauer B., Ruwisch L., and Kleuser B. Antiapoptotic action of 1alpha,25-dihydroxyvitamin D3 in primary human melanocytes. Melanoma Res 13 4 (2003) 339-347
27. Hutchinson P.E., Osborne J.E., Lear J.T., Smith A.G., Bowers P.W., Morris P.N., et al. Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma. Clin Cancer Res 6 2 (2000) 498-504
28. Slominski A., Wortsman J., and Tobin D.J. The cutaneous serotoninergic/melatoninergic system: securing a place under the sun. FASEB J 19 2 (2005) 176-194
29. Kiratli H., Gedik S., Us D., and Bilgic S. Serum melatonin levels following enucleation and transpupillary thermotherapy in patients with choroidal melanoma. Clin Exp Ophthalmol 31 6 (2003) 505-508
30. Slominski A., and Pruski D. Melatonin inhibits proliferation and melanogenesis in rodent melanoma cells. Exp Cell Res 206 2 (1993) 189-194
31. Cos S., Garcia-Bolado A., and Sanchez-Barcelo E.J. Direct antiproliferative effects of melatonin on two metastatic cell sublines of mouse melanoma (B16BL6 and PG19). Melanoma Res 11 2 (2001) 197-201
32. Hu D.N., and Roberts J.E. Melatonin inhibits growth of cultured human uveal melanoma cells. Melanoma Res 7 1 (1997) 27-31
33. Kadekaro A.L., Andrade L.N., Floeter-Winter L.M., Rollag M.D., Virador V., Vieira W., et al. MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells. J Pineal Res 36 3 (2004) 204-211
34. Gonzalez R., Sanchez A., Ferguson J.A., Balmer C., Daniel C., Cohn A., et al. Melatonin therapy of advanced human malignant melanoma. Melanoma Res 1 4 (1991) 237-243
35. Yerneni L.K., and Jayaraman S. Pharmacological action of high doses of melatonin on B16 murine melanoma cells depends on cell number at time of exposure. Melanoma Res 13 2 (2003) 113-117
36. Fiala K.H., Whetteckey J., and Manyam B.V. Malignant melanoma and levodopa in Parkinson's disease: causality or coincidence?. Parkinsonism Relat Disord 9 6 (2003) 321-327
37. Fahn S., Snider S., Prasad A.L., Lane E., and Makadon H. Normalization of brain serotonin by l-tryptophan in levodopa-treated rats. Neurology 25 9 (1975) 861-865
38. Willis G.L. The therapeutic effects of dopamine replacement therapy and its psychiatric side effects are mediated by pineal function. Behav Brain Res 160 1 (2005) 148-160
39. Kanzleiter T, Schneider T, Walter I, Bolze F, Eickhorst C, Heldmaier G, Klaus S, Klingenspor M. Evidence for NR4A1 as a cold-induced effector of brown fat thermogenesis. Physiol Genomics; 2005 Oct 11 [Epub ahead of print].
40. Yun A.J., Lee P.Y., and Bazar K.A. Temporal variation of autonomic balance and diseases during circadian, seasonal, reproductive, and lifespan cycles. Med Hypotheses 63 1 (2004) 155-162
41. Davis M.S., Malayer J.R., Vandeventer L., Royer C.M., McKenzie E.C., and Williamson K.K. Cold weather exercise and airway cytokine expression. J Appl Physiol 98 6 (2005) 2132-2136
42. Wanderer A.A., and Hoffman H.M. The spectrum of acquired and familial cold-induced urticaria/urticaria-like syndromes. Immunol Allergy Clin North Am 24 2 (2004) 259-286
43. Kikuchi K., Kobayashi H., Hirao T., Ito A., Takahashi H., and Tagami H. Improvement of mild inflammatory changes of the facial skin induced by winter environment with daily applications of a moisturizing cream. A half-side test of biophysical skin parameters, cytokine expression pattern and the formation of cornified envelope. Dermatology 207 3 (2003) 269-275
44. Prabhakar N.R., Fields R.D., Baker T., and Fletcher E.C. Intermittent hypoxia: cell to system. Am J Physiol Lung Cell Mol Physiol 281 (2001) L524-L528
45. Chakrabarty K., and Fahim M. Modulation of the contractile responses of guinea pig isolated tracheal rings after chronic intermittent hypobaric hypoxia with and without cold exposure. J Appl Physiol 99 3 (2005) 1006-1011
46. Yun A.J., Lee P.Y., and Bazar K.A. Can thromboembolism be the result, rather than the inciting cause, of acute vascular events such as stroke, pulmonary embolism, mesenteric ischemia, and venous thrombosis?: a maladaptation of the prehistoric trauma response. Med Hypotheses 64 4 (2004) 706-716
47. Yun A.J., Lee P.Y., and Bazar K.A. Acute coronary syndromes and heart failure may reflect maladaptations of trauma physiology that was shaped during pre-modern evolution. Med Hypotheses 62 6 (2004) 861-867
48. West J.B. The physiologic basis of high-altitude diseases. Ann Intern Med 141 (2004) 789-800
49. Kinsman T.A., Townsend N.E., Gore C.J., Hahn A.G., Clark S.A., Aughey R.J., et al. Sleep disturbance at simulated altitude indicated by stratified respiratory disturbance index but not hypoxic ventilatory response. Eur J Appl Physiol 94 5-6 (2005) 569-575
50. Yun A.J., Bazar K.A., Gerber A., Lee P.Y., and Daniel S.M. The dynamic range of biologic functions and variation of many environmental cues may be declining in the modern age: implications for diseases and therapeutics. Med Hypotheses 65 1 (2005) 173-178
51. Llorca J., Guerrero P., Prieto-Salceda D., and Dierssen-Sotos T. Mortality of multiple sclerosis in Spain: demonstration of a north-South gradient. Neuroepidemiology 24 3 (2005) 135-140
52. Ogawa G., Mochizuki H., Kanzaki M., Kaida K., Motoyoshi K., and Kamakura K. Seasonal variation of multiple sclerosis exacerbations in Japan. Neurol Sci 24 6 (2004) 417-419
53. Rosen L.N., Livingstone I.R., and Rosenthal N.E. Multiple sclerosis and latitude: a new perspective on an old association. Med Hypotheses 36 4 (1991) 376-378
54. Hutter C.D., and Laing P. Multiple sclerosis: sunlight, diet, immunology and aetiology. Med Hypotheses 46 2 (1996) 67-74
55. Yun A.J., Lee P.Y., Bazar K.A., Daniel S.M., and Doux J.D. The incorporation of iodine in thyroid hormone may stem from its role as a prehistoric signal of ecologic opportunity: an evolutionary perspective and implications for modern diseases. Med Hypotheses 65 4 (2005) 804-810
56. Albrecht-Buehler G. Changes of cell behavior by near-infrared signals. Cell Motil Cytoskeleton 32 4 (1995) 299-304