Mortality of multiple sclerosis in Spain: Demonstration of a north-south gradient

Neuroepidemiology

Volumn 24, Issue 3, 2005, Pages 135-140

  Llorca, Javier ^a,b   Guerrero, Paula ^a   Prieto Salceda, Dolores ^a   Dierssen Sotos, Trinidad ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Geographical distribution; Mortality; Multiple sclerosis; Spain

Indexed keywords

ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GEOGRAPHIC DISTRIBUTION; HUMAN; LATITUDE; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIPLE SCLEROSIS; POPULATION RESEARCH; SPAIN; STANDARDIZATION; TECHNIQUE; ADULT; AGE; AGED; EPIDEMIOLOGY; GEOGRAPHY; MIDDLE AGED; SEX DIFFERENCE;

ADULT; AGE FACTORS; AGED; EPIDEMIOLOGIC STUDIES; FEMALE; GEOGRAPHY; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; SEX FACTORS; SPAIN;

EID: 18744399324     PISSN: 02515350     EISSN: None     Source Type: Journal    
DOI: 10.1159/000083296     Document Type: Article

References (14)

1. Kurtzke J: Geography in multiple sclerosis. J Neurol 1977;215:1-26.
2. Bar-Or A, Smith DR: Multiple sclerosis; in Batchelor T, Cudkowics ME (eds): Principles of Neuroepidemiology. Woburn, ButterworthHeinemann, 2001, pp 125-151.
3. Gronning M, Mellgren SI: Multiple sclerosis in the two northernmost counties of Norway. Acta Neurol Scand 1985;72:321-327.
4. Pugliatti M, Sotgiu S, Rosati G: The worldwide prevalence of multiple sclerosis. Clin Neurol Neurosurg 2002;104:182-191.
5. Van der Mei IAF, Ponsonby AL, Blizzard L, Dwyer T: Regional variation in multiple sclerosis prevalence in Australia and its association with ambient ultraviolet radiation. Neuroepidemiology 2001;20:168-174.
6. Martyn CN, Cruddas M, Compston DA: Symptomatic Epstein-Barr virus infections and multiple sclerosis. J Neurol Neurosurg Psychiatry 1993;56:167-168.
7. Modrego PJ, Pina MA, Lopez A, Errea JM: Prevalence of multiple sclerosis in the province of Teruel, Spain. J Neurol 1997;244:182-185.
8. Bufill E, Blesa R, Galan I, Dean G: Prevalence of multiple sclerosis in the region of Osona. Catalonia, northern Spain. J Neurol Neurosurg Psychiatry 1995;58:577-581.
9. Pina MA, Ara JR, Modrego PJ, Morales F, Capablo JL: Prevalence of multiple sclerosis in the sanitary district of Calatayud, Northern Spain: Is Spain a zone of high risk for this disease? Neuroepidemiology 1998;17:258-264.
10. Tola MA, Yugueros MI, Fernandez-Buey N, Fernandez-Herranz R: Prevalence of multiple sclerosis in Valladolid, northern Spain. J Neurol 1999;246:170-174.
11. Uría DF, Calatayud MT, Virgala P, Diaz A, Chamizo C, Dean G: Multiple sclerosis in Gijon health district, Asturias, Northern Spain. Acta Neurol Scan 1997;96:375-379.
12. Gonzalez-Gay MA, Garcia-Porrua C, Hajeer AH: The HLA-DRB1 influence in the susceptibility and severity to rheumatoid arthritis. Semin Arthritis Rheum 2002;31:355-360.
13. Williams ES, Jones DR, McKeran RO: Mortality rates from multiple sclerosis: Geographical and temporal variations revisited. J Neurol Neursurg Psychiatry 1991;54:104-109.
14. Warren S, Warren KG, Svenson LW, Schopflocher DP, Jones A: Geographic and temporal distribution of mortality rates for multiple sclerosis in Canada, 1965-1994. Neuroepidemiology 2003;22:75-91.