Cold weather exercise and airway cytokine expression

Journal of Applied Physiology

Volumn 98, Issue 6, 2005, Pages 2132-2136

  Davis, Michael S ^a,b   Malayer, Jerry R ^a   Vandeventer, Lori ^a   Royer, Christopher M ^a   McKenzie, Erica C ^a   Williamson, Katherine K ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b 264 McElroy Hall ^*  (United States)

Author keywords

Cell mediated immunity; Exercise induced asthma; Horses; Humoral immunity

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; ATHLETE; CELL COUNT; CELLULAR IMMUNITY; COLD EXPOSURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITHELIUM CELL; EXERCISE; EXERCISE INDUCED ASTHMA; HORSE; HUMORAL IMMUNITY; LUNG LAVAGE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROOM TEMPERATURE; TH2 CELL;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; COLD; CROSS-OVER STUDIES; CYTOKINES; ERYTHROBLASTS; GENE EXPRESSION REGULATION; HORSES; PHYSICAL CONDITIONING, ANIMAL; WEATHER;

EID: 19444387975     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.01218.2004     Document Type: Article

References (42)

1. ABI. Prism Sequence Detection System User Bulletin. Boston, MA: Perkin Elmer Applied Biosystems, 2004.
2. Ainsworth DM, Appleton JA, Bicker SW, Luce R, Flaminio MJ, and Antczak DF. The effect of strenuous exercise on mRNA concentrations of interleukin-12, interferon-gamma and interleukin-4 in equine pulmonary and peripheral blood mononuclear cells. Vet Immunol Immunopathol 91: 61-71, 2005.
3. Bracher V, Von Fellenberg R, Winder CN, Gruenig G, and Hermann M, and Kraehenmann A. An investigation of the incidence of chronic obstructive pulmonary disease (COPD) in random populations of Swiss horses. Equine Vet J 23: 136-141, 1991.
4. Bradding P and Holgate ST. The mast cell as a source of cytokines in asthma. Ann NY Acad Sci 796: 272-281, 1996.
5. Bradding P, Roberts JA, Britten KM, Montefort S, Djukanovic R, Mueller R, Heusser CH, Howarth PH, and Holgate ST. Interleukin-4, -5, and -6 and tumor necrosis factor-α in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 10: 471-480, 1994.
6. Cordeau ME, Joubert P, Dewachi O, Hamid Q, and Lavoie JP. IL-4, IL-5 and IFN-gamma mRNA expression in pulmonary lymphocytes in equine heaves. Vet Immunol Immunopathol 97: 87-96, 2004.
7. Davis JM, Kohut ML, Colbert LH, Jackson DA, Ghaffar A, and Mayer EP. Exercise, alveolar macrophage function, and susceptibility to respiratory infection. J Appl Physiol 83: 1461-1466, 1997.
8. Davis MS, Lockard AJ, Marlin DJ, and Freed AN. Airway cooling and mucosal injury during cold weather exercise. Equine Vet J Suppl 34: 413-416, 2002.
9. Eggelston PA, Kagey-Sobotka A, and Lichtenstein LM. A comparison of the osmotic activation of basophils and human lung mast cells. Am Rev Respir Dis 135: 1043-1048, 1987.
10. Eggleston PA, Kagey-Sobotka A, Schleimer RP, and Lichtenstein LM. Interaction between hyperosmolar and IgE-mediated histamine release from basophils and mast cells. Am Rev Respir Dis 130: 86-91, 1984.
11. Elenkov IJ. Systemic stress-induced Th2 shift and its clinical implications. Int Rev Neurobiol 52: 163-186, 2002.
12. Elenkov IJ. Glucocorticoids and the Th1/Th2 balance. Ann NY Acad Sci 1024: 138-146, 2004.
13. Finnerty JP, Harvey A, and Holgate ST. The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma. Eur Respir J 5: 323-330, 1992.
14. Finnerty JP and Holgate ST. Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination. Eur Respir J 3: 540-547, 1990.
15. Finnerty JP and Holgate ST. The contribution of histamine release and vagal reflexes, alone and in combination, to exercise-induced asthma. Eur Respir J 6: 1132-1137, 1993.
16. Folsom RW, Littlefield-Chabaud MA, French DD, Pourciau SS, Mistric L, and Horohov DW. Exercise alters the immune response to equine influenza virus and increases susceptibility to infection. Equine Vet J 33: 664-669, 2001.
17. Freed AN and Davis MS. Animal models, athletes, and the development of exercise-induced asthma. In: Exercise-Induced Asthma: Pathophysiology and Treatment, edited by Rundell KW, Wilber RL, and Lemanske RF. Champaign, IL: Human Kinetics, 2002, p. 101-150.
18. Freed AN, Omori C, Schofield BH, and Mitzner W. Dry air-induced mucosal cell injury and bronchovascular leakage in canine peripheral airways. Am J Respir Cell Mol Biol 11: 724-732, 1994.
19. Hashimoto S, Gon Y, Matsumoto K, Takeshita I, Maruoka S, and Horie T. Inhalant corticosteroids inhibit hyperosmolarity-induced, and cooling and rewarming-induced interieukin-8 and RANTES production by human bronchial epithelial cells. Am J Respir Crit Care Med 162: 1075-1080, 2000.
20. Hashimoto S, Matsumoto K, Gon Y, Nakayama T, Takeshita I, and Horie T. Hyperosmolarity-induced interleukin-8 expression in human bronchial epithelial cells through p38 mitogen-activated protein kinase. Am J Respir Crit Care Med 159: 634-640, 1999.
21. Karjalainen EM, Laitinen A, Sue-Chu M, Altraja A, Bjermer L, and Laitinen LA. Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine. Am J Respir Crit Care Med 161: 2086-2091, 2000.
22. Kohut ML, Boehm GW, and Moynihan JA. Prolonged exercise suppresses antigen-specific cytokine response to upper respiratory infection. J Appl Physiol 90: 678-684, 2001.
23. Lavoie JP, Maghni K, Desnoyers M, Taha R, Martin JG, and Hamid QA. Neutrophilic airway inflammation in horses with heaves is characterized by a Th2-type cytokine profile. Am J Respir Crit Care Med 164: 1410-1413, 2001.
24. Lee TH, Brown MJ, Nagy L, Causon R, Walport MJ, and Kay AB. Exercise-induced release of histamine and neutrophil chemotactic factor in atopic asthmatics. J Allergy Clin Immunol 70: 73-81, 1982.
25. Lee TH, Nagakura T, Cromwell O, Brown MJ, Causon R, and Kay AB. Neutrophil chemotactic activity and histamine in atopic and nonatopic subjects after exercise-induced asthma. Am Rev Respir Dis 129: 409-412, 1984.
26. Lekeux P and Art T. The respiratory system: anatomy, physiology, and adaptations to exercise and training. In: The Athletic Horse: Principles and Practice of Equine Sports Medicine, edited by Hodgson DR and Rose RJ. Philadelphia, PA: Saunders, 1994, p. 79-127.
27. Levite M. Neuropeptides, by direct interaction with T-cells, induce cytokine secretion and break the commitment to a specific T helper phenotype. Proc Natl Acad Sci USA 95: 12544-12549, 1998.
28. Lim KG and Weller PF. Lymphokines. In: Asthma, edited by Barnes PJ, Grunstein MM, Leff AR, and Woolcock AJ. Philadelphia, PA: Lippincott-Raven, 1997, p. 663-672.
29. Lucey DR, Clerici M, and Shearer GM. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin Microbiol Rev 9: 532-562, 1996.
30. Maghni K, Taha R, Afif W, Hamid Q, and Martin JG. Dichotomy between neurokinin receptor actions in modulating allergic airway-responses in an animal model of helper T cell type 2 cytokine-associated inflammation. Am J Respir Crit Care Med 162: 1068-1074, 2000.
31. McFadden ER Jr (Editor). Exercise-Induced Asthma. New York: Dekker, 1999, vol. 130. (Lung Biol Health Dis Ser)
32. McGorum BC, Dixon PM, and Halliwell RE. Responses of horses affected with chronic obstructive pulmonary disease to inhalation challenges with mould antigens. Equine Vet J 25: 261-267, 1993.
33. McGorum BC, Dixon PM, and Halliwell REW. Evaluation of intradermal mould antigen testing in the diagnosis of equine chronic obstructive pulmonary disease. Equine Vet J 25: 273-275, 1993.
34. Nielsen HG and Lyberg T. Long-distance running modulates the expression of leucocyte and endothelial adhesion molecules. Scand J Immunol 60: 356-362, 2004.
35. O'Cain CF, Dowling NB, Slutsky AS, Hensley MJ, Strohh KP, Mc-Fadden ER Jr, and Ingram RH Jr. Airway effects of respiratory heat loss in normal subjects. J Appl Physiol 49: 875-880, 1980.
36. Omori C, Schofield BH, Mitzner W, and Freed AN. Hyperpnea with dry air causes time-dependent alterations in mucosal morphology and bronchovascular permeability. J Appl Physiol 78: 1043-1051, 1995.
37. Pliss LB, Ingenito EP, Ingram RH, and Pichurko B. Assessment of bronchoalveolar cell and mediator response to isocapnic hyperpnea in asthma. Am Rev Respir Dis 142: 73-78, 1990.
38. Robinson NE, Derksen FJ, Olszewski MA, and Buechner-Maxwell VA. The pathogenesis of chronic obstructive pulmonary disease of horses. Br Vet J 152: 283-305, 1996.
39. Sue-Chu M, Larsson L, and Bjermer L. Prevalence of asthma in young cross-country skiers in central Scandinavia: differences between Norway and Sweden. Respir Med 90: 99-105, 1996.
40. Sue-Chu M, Larsson L, Moen T, Rennard SI, and Bjermer L. Bronchscopy and bronchoalveolar lavage findings in cross-country skiers with and without "ski asthma." Eur Respir J 13: 626-632, 1999.
41. Suzuki K, Yamada M, Kurakake S, Okamura N, Yamaya K, Liu Q, Kudoh S, Kowatari K, Nakaji S, and Sugawara K. Circulating cytokines and hormones with immunosuppressive but neutrophil-priming potentials rise after endurance exercise in humans. Eur J Appl Physiol 81: 281-287, 2000.
42. Umetsu DT, Akbari O, and DeKruyff RH. Regulatory T cells control the development of allergic disease and asthma. J Allergy Clin Immunol 112: 480-487, 2003.