Assesing the instability of the isoelectric focusing patterns of erythropoietin in urine

Electrophoresis

Volumn 27, Issue 22, 2006, Pages 4387-4395

  Belalcazar, Viviana ^a,b   Gutiérrez Gallego, Ricardo ^a,b,c   Llop, Esther ^a,b   Segura, Jordi ^a,b   Pascual, José Antonio ^a,b  

^a INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c NONE   (Spain)

Author keywords

Doping control; Erythropoietin; IEF; Neuraminidase; Sulfatase

Indexed keywords

RECOMBINANT PROTEINS;

ARYLSULFATASE; DOPING CONTROL; ERYTHROPOIETIN; HUMAN ERYTHROPOIETIN; IEF; ISOELECTRIC FOCUSING; NEURAMINIDASE; SIALIDASES; SULFATASES; URINE SAMPLE;

ELECTROPHORESIS;

ARYLSULFATASE; CARBOHYDRATE; ERYTHROPOIETIN; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; RECOMBINANT ERYTHROPOIETIN; SIALIC ACID; SIALIDASE; DRUG DERIVATIVE; ISOPROTEIN; NESP PROTEIN, HUMAN;

ARTICLE; ARTIFACT; CONTROLLED STUDY; DEGLYCOSYLATION; DIAGNOSTIC VALUE; DOPING; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; FALSE NEGATIVE RESULT; HELIX POMATIA; HORMONE DETERMINATION; HUMAN; ISOELECTRIC FOCUSING; LABORATORY TEST; NONHUMAN; SIALYLATION; URINALYSIS; ANIMAL; ENZYMOLOGY; GLYCOSYLATION; HELIX (SNAIL); ISOELECTRIC POINT; METABOLISM; METHODOLOGY; SUBSTANCE ABUSE; URINE;

ANIMALS; ARYLSULFATASES; DOPING IN SPORTS; ERYTHROPOIETIN; ERYTHROPOIETIN, RECOMBINANT; GLYCOSYLATION; HELIX (SNAILS); HUMANS; ISOELECTRIC FOCUSING; ISOELECTRIC POINT; PROTEIN ISOFORMS; SUBSTANCE ABUSE DETECTION;

EID: 33845287263     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200500891     Document Type: Article

References (31)

1. Maiese, K., Li, F, Chong, Z. Z., JAMA 2005, 293, 90-95.
2. Genc, S., Koroglu, T. F, Genc, K., Brain Res. 2004, 1000, 19-31.
3. Choi, D., Kim, M., Park, J., J. Chromatogr. B,. 1996, 687, 189-199.
4. Grabenhorst, E., Schlenke, P., Pohl, S., Nimtz, M. et al., Glycoconj. J. 1999, 16, 81-97.
5. Toledo, J. R., Sanchez, O., Montesino, S. R., Fernandez, G. Y. et al., Biochim. Biophys. Acta 2005, 1726, 48-56.
6. Takeuchi, M., Kobata, A., Glycobiology 1991, 1, 337-346.
7. Zhou, Q., Park, S. H., Boucher, S., Higgins, E. et al., Anal. Biochem. 2004, 335, 10-16.
8. Elliott, S., Egrie, J., Browne, J., Lorenzini, T. et al., Exp. Hematol. 2004, 32, 1146-1155.
9. Imai, N., Higuchi, M., Kawamura, A., Tomonoh, K. et al., Eur. J. Biochem. 1990, 194, 457-462.
10. Yuen, C. T., Storring, P. L., Tiplady, R. J., Izquierdo, M. et al., Br. J. Haematol. 2003, 121, 511-526.
11. Egrie, J. C., Browne, J. K., Br. J. Cancer 2001, 84, 3-10.
12. Egrie, J. C., Browne, J. K., Nephrol. Dial. Transplant. 2001, 16, 3-13.
13. Lasne, F., Martin, L., Crepin, N., de Ceaurriz, J., Anal. Biochem. 2002, 311, 119-126.
14. Lasne, F, de Ceaurriz, J., Nature 2000, 405, 635.
15. Blom, N., Sicheritz-Ponten, T., Gupta, R., Gammeltoft, S. et al., Proteomics 2004, 4, 1633-1649.
16. Hemmerich, S., Verdugo, D., Rath, V. L., Drug Discov. Today 2004, 9, 967-975.
17. Wada Technical document: TD2004EPO, World Anti-Doping Agency (WADA) 2004, p. 1.
18. Lasne, F., J. Immunol. Methods 2001, 253, 125-131.
19. Stubiger, G., Marchetti, M., Nagano, M., Reichel, C. et al., Rapid Commun. Mass Spectrom. 2005, 19, 728-742.
20. Varki, A., Kornfeld, S., J. Biol. Chem. 1980, 255, 10847-10858.
21. Shackelford, D. A., Strominger, J. L., J. Exp. Med. 1980, 151, 144-165.
22. Ohta, M., Kawasaki, N., Hyuga, S., Hyuga, M. et al., J. Chromatogr. A 2001, 910, 1-11.
23. Kawasaki, N., Haishima, Y., Ohta, M., Itoh, S. et al., Glycobiology 2001, 11, 1043-1049.
24. Yamaguchi, Y., Hayashi, C., Miyai, K., Clin. Chem. 1987, 33, 418.
25. Roy, A. B., Methods Enzymol. 1987, 143, 361-366.
26. Lee, E. U., Roth, J., Paulson, J. C., J. Biol. Chem. 1989, 264, 13848-13855.
27. Breidbach, A., Catlin, D. H., Green, G. A., Tregub, I. et al., Clin. Chem. 2003, 49, 901-907.
28. Stevens, R. L., Fluharty, A. L., Skokut, M. H., Kihara, H., J. Biol. Chem. 1975, 250, 2495-2501.
29. Laidler, P. M., Waheed, A., Van Etten, R. L., Biochim. Biophys. Acta 1985, 827, 73-83.
30. Shimizu, T, Noguchi, J., Schuebel, K., Miyake, T. et al., Exp. Cell Biol. 1986, 54, 225-233,
31. Wiggins, R., Hicks, S. J., Soothill, P. W., Millar, M. R. et al., Sex Transm. Infect. 2001, 77, 402-408.