Aluminum toxicity triggers the nuclear translocation of HIF-1α and promotes anaerobiosis in hepatocytes

Toxicology in Vitro

Volumn 21, Issue 1, 2007, Pages 16-24

  Mailloux, Ryan J ^a   Appanna, Vasu D ^a  

^a LAURENTIAN UNIVERSITY   (Canada)

Author keywords

Al toxicity; Anaerobiosis; ATP; Glucose utilization; HIF 1 ; LDH

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALUMINUM; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCOSE TRANSPORTER 1; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEXOKINASE; LACTATE DEHYDROGENASE; PYRUVATE KINASE;

ANAEROBIC METABOLISM; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL NUCLEUS; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE METABOLISM; GLYCOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LIVER TOXICITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT;

ADENOSINE TRIPHOSPHATE; ALUMINUM; ANAEROBIOSIS; CELL FRACTIONATION; CELL LINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLYCOLYSIS; HEPATOCYTES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; LIPID METABOLISM; MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION-REDUCTION; PENTOSE PHOSPHATE PATHWAY; PROTEIN TRANSPORT;

EID: 33845220006     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2006.07.013     Document Type: Article

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