Physiology of psychoneuroimmunology: A personal view

Brain, Behavior, and Immunity

Volumn 21, Issue 1, 2007, Pages 34-44

  Besedovsky, Hugo O ^a   Rey, Adriana del ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Immune neuro endocrine interactions; Immunophysiology

Indexed keywords

CYTOKINE;

ADRENERGIC SYSTEM; ANTIGEN PRESENTING CELL; ARTICLE; AVOIDANCE BEHAVIOR; BRAIN FUNCTION; BRAIN REGION; CYTOKINE PRODUCTION; GENE EXPRESSION; HUMAN; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; LEARNING; MEMORY; NEUROENDOCRINE SYSTEM; NEUROIMMUNOLOGY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; FORECASTING; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; NEUROENDOCRINOLOGY; NEUROIMMUNOMODULATION; NEUROSECRETORY SYSTEMS; PSYCHONEUROIMMUNOLOGY;

EID: 33845186911     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2006.09.008     Document Type: Article

References (39)

1. Ader R., and Cohen N. Behaviorally conditioned immunosuppression. Psychosom. Med. 37 (1975) 333-340
2. Anisman H., Merali Z., Poulter M.O., and Hayley S. Cytokines as a precipitant of depressive illness: animal and human studies. Curr. Pharm. Des. 11 (2005) 963-972
3. Avital A., Goshen I., Kamsler A., Segal M., Iverfeldt K., Richter-Levin G., and Yirmiya R. Impaired interleukin-1 signaling is associated with deficits in hippocampal memory processes and neural plasticity. Hippocampus 13 (2003) 826-834
4. Balschun D., Wetzel W., Del Rey A., Pitossi F., Schneider H., Zuschratter W., and Besedovsky H.O. Interleukin-6: a cytokine to forget. FASEB J. 18 (2004) 1788-1790
5. Besedovsky H.O., and del Rey A. Immune-neuro-endocrine interactions: facts and hypotheses. Endocr. Rev. 17 (1996) 64-102
6. Besedovsky H.O., and del Rey A. Regulating inflammation by glucocorticoids. Nat. Immunol. 7 (2006) 537
7. Besedovsky H.O., del Rey A., and Sorkin E. Lymphokine-containing supernatants from con A-stimulated cells increase corticosterone blood levels. J. Immunol. 126 (1981) 385-387
8. Besedovsky H.O., del Rey A., Sorkin E., Da Prada M., Burri R., and Honegger C. The immune response evokes changes in brain noradrenergic neurons. Science 221 (1983) 564-566
9. Besedovsky H.O., del Rey A., Sorkin E., and Dinarello C.A. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 233 (1986) 652-654
10. Besedovsky H.O., and Sorkin E. Network of immune-neuroendocrine interactions. Clin. Exp. Immunol. 27 (1977) 1-12
11. Blalock J.E., Harbour-McMenamin D., and Smith E.M. Peptide hormones shared by the neuroendocrine and immunologic systems. J. Immunol. 135 (1985) 858s-861s
12. Braida D., Sacerdote P., Panerai A.E., Bianchi M., Aloisi A.M., Iosue S., and Sala M. Cognitive function in young and adult IL (interleukin)-6 deficient mice. Behav. Brain. Res. 153 (2004) 423-429
13. Dantzer R. Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity. Eur. J. Pharmacol. 500 (2004) 399-411
14. del Rey A., and Besedovsky H. Antidiabetic effects of interleukin 1. Proc. Natl. Acad. Sci. USA 86 (1989) 5943-5947
15. del Rey A., and Besedovsky H.O. Metabolic and neuroendocrine effects of pro-inflammatory cytokines. Eur. J. Clin. Invest. 22 Suppl. 1 (1992) 10-15
16. del Rey A., Kabiersch A., Petzoldt S., and Besedovsky H.O. Involvement of noradrenergic nerves in the activation and clonal deletion of T cells stimulated by superantigen in vivo. J. Neuroimmunol. 127 (2002) 44-53
17. del Rey A., Monge-Arditi G., and Besedovsky H.O. Central and peripheral mechanisms contribute to the hypoglycemia induced by interleukin-1. Ann. N. Y. Acad. Sci. 840 (1998) 153-161
18. del Rey A., Roggero E., Kabiersch A., Schafer M., and Besedovsky H.O. The role of noradrenergic nerves in the development of the lymphoproliferative disease in Fas-deficient, lpr/lpr mice. J. Immunol. 176 (2006) 7079-7086
19. Delgado M., Pozo D., and Ganea D. The significance of vasoactive intestinal peptide in immunomodulation. Pharmacol. Rev. 56 (2004) 249-290
20. Depino A.M., Alonso M., Ferrari C., del Rey A., Anthony D., Besedovsky H., Medina J.H., and Pitossi F. Learning modulation by endogenous hippocampal IL-1: blockade of endogenous IL-1 facilitates memory formation. Hippocampus 14 (2004) 526-535
21. Elenkov I.J., Wilder R.L., Chrousos G.P., and Vizi E.S. The sympathetic nerve-an integrative interface between two supersystems: the brain and the immune system. Pharmacol. Rev. 52 (2000) 595-638
22. Heijnen C.J., and Kavelaars A. The importance of being receptive. J. Neuroimmunol. 100 (1999) 197-202
23. Jessop D.S. Neuropeptides: modulators of immune responses in health and disease. Int. Rev. Neurobiol. 52 (2002) 67-91
24. Kent S., Bluthe R.M., Dantzer R., Hardwick A.J., Kelley K.W., Rothwell N.J., and Vannice J.L. Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1. Proc. Natl. Acad. Sci. USA 89 (1992) 9117-9120
25. Maier S.F., Goehler L.E., Fleshner M., and Watkins L.R. The role of the vagus nerve in cytokine-to-brain communication. Ann. N. Y. Acad. Sci. 840 (1998) 289-300
26. Meffert M.K., and Baltimore D. Physiological functions for brain NF-kappaB. Trends Neurosci. 28 (2005) 37-43
27. Nussdorfer G.G., and Malendowicz L.K. Role of VIP, PACAP, and related peptides in the regulation of the hypothalamo-pituitary-adrenal axis. Peptides 19 (1998) 1443-1467
28. Obal Jr. F., and Krueger J.M. Biochemical regulation of non-rapid-eye-movement sleep. Front. Biosci. 8 (2003) d520-d550
29. Pitossi F., del Rey A., Kabiersch A., and Besedovsky H. Induction of cytokine transcripts in the central nervous system and pituitary following peripheral administration of endotoxin to mice. J. Neurosci. Res. 48 (1997) 287-298
30. Rogausch H., del Rey A., Kabiersch A., Reschke W., Ortel J., and Besedovsky H. Endotoxin impedes vasoconstriction in the spleen: role of endogenous interleukin-1 and sympathetic innervation. Am. J. Physiol. 272 (1997) R2048-R2054
31. Sanders V.M. Interdisciplinary research: noradrenergic regulation of adaptive immunity. Brain Behav. Immun. 20 (2006) 1-8
32. Schauenstein K., Fassler R., Dietrich H., Schwarz S., Kromer G., and Wick G. Disturbed immune-endocrine communication in autoimmune disease. Lack of corticosterone response to immune signals in obese strain chickens with spontaneous autoimmune thyroiditis. J. Immunol. 139 (1987) 1830-1833
33. Schneider H., Pitossi F., Balschun D., Wagner A., del Rey A., and Besedovsky H.O. A neuromodulatory role of interleukin-1beta in the hippocampus. Proc. Natl. Acad. Sci. USA 95 (1998) 7778-7783
34. Sternberg E.M. Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens. Nat. Rev. Immunol. 6 (2006) 318-328
35. Sternberg E.M., Hill J.M., Chrousos G.P., Kamilaris T., Listwak S.J., Gold P.W., and Wilder R.L. Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats. Proc. Natl. Acad. Sci. USA 86 (1989) 2374-2378
36. Tracey K.J. The inflammatory reflex. Nature 420 (2002) 853-859
37. Turnbull A.V., and Rivier C.L. Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action. Physiol. Rev. 79 (1999) 1-71
38. Weihe E., Nohr D., Michel S., Muller S., Zentel H.J., Fink T., and Krekel J. Molecular anatomy of the neuro-immune connection. Int. J. Neurosci. 59 (1991) 1-23
39. Yirmiya R., Winocur G., and Goshen I. Brain interleukin-1 is involved in spatial memory and passive avoidance conditioning. Neurobiol. Learn Mem. 78 (2002) 379-389