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Volumn 99, Issue 6, 2006, Pages 1688-1704

Damage and recovery of the bone growth mechanism in young rats following 5-fluorouracil acute chemotherapy

Author keywords

5 FU; Bone growth arrest; Chemotherapy; Growth plate; Osteoporosis; Side effects

Indexed keywords

ANTIMETABOLITE; FLUOROURACIL; PROTEIN BAX; PROTEIN BCL 2; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33751556806     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20889     Document Type: Article
Times cited : (48)

References (57)
  • 1
    • 0030772066 scopus 로고    scopus 로고
    • An anthropometric study of children during intensive chemotherapy for acute lymphoblastic leukaemia
    • Ahmed SF, Wallace WH, Kelnar CJ. 1997. An anthropometric study of children during intensive chemotherapy for acute lymphoblastic leukaemia. Horm Res 48:178-183.
    • (1997) Horm Res , vol.48 , pp. 178-183
    • Ahmed, S.F.1    Wallace, W.H.2    Kelnar, C.J.3
  • 3
    • 0026503676 scopus 로고
    • Carcinoembryonic antigen and carbohydrate 19-9 antigen as markers for colorectal carcinoma in children and adolescents
    • Angel CA, Pratt CB, Rao BN, Schell MJ, Parham DM, Lobe TE, Fleming ID. 1992. Carcinoembryonic antigen and carbohydrate 19-9 antigen as markers for colorectal carcinoma in children and adolescents. Cancer 69:1487-1491.
    • (1992) Cancer , vol.69 , pp. 1487-1491
    • Angel, C.A.1    Pratt, C.B.2    Rao, B.N.3    Schell, M.J.4    Parham, D.M.5    Lobe, T.E.6    Fleming, I.D.7
  • 4
    • 0024521423 scopus 로고
    • Osteogenic stem cells and the stromal system of bone and marrow
    • Beresford JN. 1989. Osteogenic stem cells and the stromal system of bone and marrow. Clin Orthop 240:278-280.
    • (1989) Clin Orthop , vol.240 , pp. 278-280
    • Beresford, J.N.1
  • 5
    • 0035225045 scopus 로고    scopus 로고
    • Protection against mucosal injury by growth factors and cytokines
    • Booth D, Potten CS. 2001. Protection against mucosal injury by growth factors and cytokines. J Natl Cancer Inst Monogr 29:16-20.
    • (2001) J Natl Cancer Inst Monogr , vol.29 , pp. 16-20
    • Booth, D.1    Potten, C.S.2
  • 6
    • 0033795684 scopus 로고    scopus 로고
    • Quantitative histomorphometric analysis of the human growth plate from birth to adolescence
    • Byers S, Moore AJ, Byard RW, Fazzalari NL. 2000. Quantitative histomorphometric analysis of the human growth plate from birth to adolescence. Bone 27:495-501.
    • (2000) Bone , vol.27 , pp. 495-501
    • Byers, S.1    Moore, A.J.2    Byard, R.W.3    Fazzalari, N.L.4
  • 9
    • 13544258900 scopus 로고    scopus 로고
    • Pre-treatment with insulin-like growth factor-I partially ameliorates 5-fluorouracil-induced intestinal mucositis in rats
    • Cool JC, Dyer JL, Xian CJ, Butler RN, Geier MS, Howarth GS. 2005. Pre-treatment with insulin-like growth factor-I partially ameliorates 5-fluorouracil-induced intestinal mucositis in rats. Growth Horm IGF Res 15:72-82.
    • (2005) Growth Horm IGF Res , vol.15 , pp. 72-82
    • Cool, J.C.1    Dyer, J.L.2    Xian, C.J.3    Butler, R.N.4    Geier, M.S.5    Howarth, G.S.6
  • 11
    • 0037786552 scopus 로고    scopus 로고
    • Sequential histomorphometric analysis of the growth plate following irradiation with and without radioprotection
    • Damron TA, Margulies BS, Strauss JA, O'Hara K, Spadaro JA, Farnum CE. 2003. Sequential histomorphometric analysis of the growth plate following irradiation with and without radioprotection. J Bone Joint Surg Am 85-A:1302-1313.
    • (2003) J Bone Joint Surg Am , vol.85 A , pp. 1302-1313
    • Damron, T.A.1    Margulies, B.S.2    Strauss, J.A.3    O'Hara, K.4    Spadaro, J.A.5    Farnum, C.E.6
  • 12
    • 0036021073 scopus 로고    scopus 로고
    • In vitro effects of combination chemotherapy on osteoblasts: Implications for osteopenia in childhood malignancy
    • Davies JH, Evans BA, Jenney ME, Gregory JW. 2002. In vitro effects of combination chemotherapy on osteoblasts: Implications for osteopenia in childhood malignancy. Bone 31:319-326.
    • (2002) Bone , vol.31 , pp. 319-326
    • Davies, J.H.1    Evans, B.A.2    Jenney, M.E.3    Gregory, J.W.4
  • 13
    • 0031974274 scopus 로고    scopus 로고
    • Mitochondria in chemotherapy-induced apoptosis: A prospective novel target of cancer therapy
    • (review)
    • Decaudin D, Marzo I, Brenner C, Kroemer G. 1998. Mitochondria in chemotherapy-induced apoptosis: A prospective novel target of cancer therapy (review). Int J Oncol 12:141-152.
    • (1998) Int J Oncol , vol.12 , pp. 141-152
    • Decaudin, D.1    Marzo, I.2    Brenner, C.3    Kroemer, G.4
  • 14
    • 0030938012 scopus 로고    scopus 로고
    • Quantitative analysis of trabecular morphogenesis in the human costochondral junction during the postnatal period in normal subjects
    • Fazzalari NL, Moore AJ, Byers S, Byard RW. 1997. Quantitative analysis of trabecular morphogenesis in the human costochondral junction during the postnatal period in normal subjects. Anat Rec 248:1-12.
    • (1997) Anat Rec , vol.248 , pp. 1-12
    • Fazzalari, N.L.1    Moore, A.J.2    Byers, S.3    Byard, R.W.4
  • 15
    • 0021248678 scopus 로고
    • Effects of chemotherapeutic agents on bone: Short-term methotrexate and doxorubicin treatment in a rat model
    • Friedlanender GE, Tross RB, Doganis AC, Kirkwood JM, Baron R. 1984. Effects of chemotherapeutic agents on bone: Short-term methotrexate and doxorubicin treatment in a rat model. J Bone Joint Surg 66A:602-607.
    • (1984) J Bone Joint Surg , vol.66 A , pp. 602-607
    • Friedlanender, G.E.1    Tross, R.B.2    Doganis, A.C.3    Kirkwood, J.M.4    Baron, R.5
  • 16
    • 0032742205 scopus 로고    scopus 로고
    • Cytotoxic drugs and the CD95 pathway
    • Friesen C, Fulda S, Debatin KM. 1999. Cytotoxic drugs and the CD95 pathway. Leukemia 13:1854-1858.
    • (1999) Leukemia , vol.13 , pp. 1854-1858
    • Friesen, C.1    Fulda, S.2    Debatin, K.M.3
  • 18
  • 19
    • 0032408999 scopus 로고    scopus 로고
    • Growth and body composition in response to chemotherapy in children with acute lymphoblastic leukemia
    • Halton JM, Atkinson SA, Barr RD. 1998. Growth and body composition in response to chemotherapy in children with acute lymphoblastic leukemia. Int J Cancer Suppl 11:81-84.
    • (1998) Int J Cancer Suppl , vol.11 , pp. 81-84
    • Halton, J.M.1    Atkinson, S.A.2    Barr, R.D.3
  • 20
    • 0017047914 scopus 로고
    • Differential recovery of intestine, bone marrow, and thymus of rats with solid tumors following 5-fluorouracil administration
    • Hopkins HA, Kovacs CJ, Looney WB, Wakefield JA. 1976. Differential recovery of intestine, bone marrow, and thymus of rats with solid tumors following 5-fluorouracil administration. Cancer Biochem Biophys 1:303-312.
    • (1976) Cancer Biochem Biophys , vol.1 , pp. 303-312
    • Hopkins, H.A.1    Kovacs, C.J.2    Looney, W.B.3    Wakefield, J.A.4
  • 21
    • 0030980032 scopus 로고    scopus 로고
    • Immunolocalization of tissue non-specific alkaline phosphatase in mice
    • Hoshi K, Amizuka N, Oda K, Ikehara Y, Ozawa H. 1997. Immunolocalization of tissue non-specific alkaline phosphatase in mice. Histochem Cell Biol 107:183-191.
    • (1997) Histochem Cell Biol , vol.107 , pp. 183-191
    • Hoshi, K.1    Amizuka, N.2    Oda, K.3    Ikehara, Y.4    Ozawa, H.5
  • 22
    • 0032953873 scopus 로고    scopus 로고
    • FGF-2 enhances intestinal stem cell survival and its expression is induced after radiation injury
    • Houchen CW, George RJ, Sturmoski MA, Cohn SM. 1999. FGF-2 enhances intestinal stem cell survival and its expression is induced after radiation injury. Am J Physiol 276:G249-G258.
    • (1999) Am J Physiol , vol.276
    • Houchen, C.W.1    George, R.J.2    Sturmoski, M.A.3    Cohn, S.M.4
  • 23
    • 0025122047 scopus 로고
    • Growth plate physiology and pathology
    • Ianotti JP. 1990. Growth plate physiology and pathology. Orthop Clin N Am 21:1-17.
    • (1990) Orthop Clin N Am , vol.21 , pp. 1-17
    • Ianotti, J.P.1
  • 25
    • 0027360091 scopus 로고
    • Cell kinetics and the control of bone growth
    • Kember NF. 1993. Cell kinetics and the control of bone growth. Acta Paediatr Suppl 82(Suppl 391):61-65.
    • (1993) Acta Paediatr Suppl , vol.82 , Issue.SUPPL. 391 , pp. 61-65
    • Kember, N.F.1
  • 28
    • 0036289137 scopus 로고    scopus 로고
    • Validation of a quantitative method for real time PCR kinetics
    • Liu W, Saint DA. 2002. Validation of a quantitative method for real time PCR kinetics. Biochem Biophys Res Commun 294:347-353.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 347-353
    • Liu, W.1    Saint, D.A.2
  • 29
    • 0034889271 scopus 로고    scopus 로고
    • Osteogenesis and bone-marrow-derived cells
    • Long MW. 2001. Osteogenesis and bone-marrow-derived cells. Blood Cells Mol Dis 27:677-690.
    • (2001) Blood Cells Mol Dis , vol.27 , pp. 677-690
    • Long, M.W.1
  • 30
    • 0038387494 scopus 로고    scopus 로고
    • 5-Fluorouracil: Mechanisms of action and clinical strategies
    • Longley DB, Harkin DP, Johnston PG. 2003. 5-fluorouracil: Mechanisms of action and clinical strategies. Nat Rev Cancer 3:330-338.
    • (2003) Nat Rev Cancer , vol.3 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 31
    • 0024429248 scopus 로고    scopus 로고
    • Osteoclast biology: Lessons from mammalian mutations
    • Marks SC, Jr. 1998. Osteoclast biology: Lessons from mammalian mutations. Am J Med Genet 34:43-54.
    • (1998) Am J Med Genet , vol.34 , pp. 43-54
    • Marks Jr., S.C.1
  • 32
    • 0035186731 scopus 로고    scopus 로고
    • Local IGF-I expression and bone formation
    • McCarthy TL, Centrella M. 2001. Local IGF-I expression and bone formation. Growth Horm IGF Res 11:213-219.
    • (2001) Growth Horm IGF Res , vol.11 , pp. 213-219
    • McCarthy, T.L.1    Centrella, M.2
  • 33
    • 0036315760 scopus 로고    scopus 로고
    • The impact of corticosteroids on growth and bone health
    • Mushtaq T, Ahmed SF. 2002. The impact of corticosteroids on growth and bone health. Arch Dis Child 87:93-96.
    • (2002) Arch Dis Child , vol.87 , pp. 93-96
    • Mushtaq, T.1    Ahmed, S.F.2
  • 36
    • 0031863992 scopus 로고    scopus 로고
    • Chemotherapeutic agents used in the treatment of childhood malignancies have direct effects on growth plate chondrocyte proliferation
    • Robson H, Anderson E, Eden OB, Isaksson O, Shaler SM. 1998. Chemotherapeutic agents used in the treatment of childhood malignancies have direct effects on growth plate chondrocyte proliferation. J Endocrinol 157:225-235.
    • (1998) J Endocrinol , vol.157 , pp. 225-235
    • Robson, H.1    Anderson, E.2    Eden, O.B.3    Isaksson, O.4    Shaler, S.M.5
  • 37
    • 0031734292 scopus 로고    scopus 로고
    • The potential role of transforming growth factor beta in fracture healing
    • Rosier RN, O'Keefe RJ, Hicks DG. 1998. The potential role of transforming growth factor beta in fracture healing. Clin Orthop Relat Res 355(Suppl):S294-S300.
    • (1998) Clin Orthop Relat Res , vol.355 , Issue.SUPPL.
    • Rosier, R.N.1    O'Keefe, R.J.2    Hicks, D.G.3
  • 38
    • 0032803131 scopus 로고    scopus 로고
    • Clinical remission of xeroderma pigmentosum-associated squamous cell carcinoma with isotretinoin and chemotherapy: Case report
    • Saade M, Debahy NE, Houjeily S. 1999. Clinical remission of xeroderma pigmentosum-associated squamous cell carcinoma with isotretinoin and chemotherapy: Case report. J Chemother 11:313-317.
    • (1999) J Chemother , vol.11 , pp. 313-317
    • Saade, M.1    Debahy, N.E.2    Houjeily, S.3
  • 39
    • 0031021315 scopus 로고    scopus 로고
    • Growth and growth hormone secretion after treatment for childhood non-Hodgkin's lymphoma
    • Samuelsson BO, Marky I, Rosberg S, Albertsson-Wikland K. 1997. Growth and growth hormone secretion after treatment for childhood non-Hodgkin's lymphoma. Med Pediatr Oncol 28:27-34.
    • (1997) Med Pediatr Oncol , vol.28 , pp. 27-34
    • Samuelsson, B.O.1    Marky, I.2    Rosberg, S.3    Albertsson-Wikland, K.4
  • 40
    • 0036246322 scopus 로고    scopus 로고
    • Alterations in the growth plate cartilage of rats with renal failure receiving corticosteroid therapy
    • Sanchez CP, He YZ. 2002. Alterations in the growth plate cartilage of rats with renal failure receiving corticosteroid therapy. Bone 30:692-698.
    • (2002) Bone , vol.30 , pp. 692-698
    • Sanchez, C.P.1    He, Y.Z.2
  • 42
    • 0026099487 scopus 로고
    • Abnormal growth patterns and adult short satture in 115 long-term survivors of childhood leukemia
    • Schriock EA, Schell MJ, Carter M, Hustu O, Ochs JJ. 1991. Abnormal growth patterns and adult short satture in 115 long-term survivors of childhood leukemia. J Clin Oncol 9:400-405.
    • (1991) J Clin Oncol , vol.9 , pp. 400-405
    • Schriock, E.A.1    Schell, M.J.2    Carter, M.3    Hustu, O.4    Ochs, J.J.5
  • 43
    • 0036426993 scopus 로고    scopus 로고
    • Effects of chemotherapy on bone metabolism and skeletal growth
    • Siebler T, Shalet SM, Robson H. 2002. Effects of chemotherapy on bone metabolism and skeletal growth. Horm Res 58(Suppl 1):80-85.
    • (2002) Horm Res , vol.58 , Issue.SUPPL. 1 , pp. 80-85
    • Siebler, T.1    Shalet, S.M.2    Robson, H.3
  • 45
    • 0033978032 scopus 로고    scopus 로고
    • Mitomycin C and 5-fluorouracil antimetabolite therapy for pediatric glaucoma filtration surgery
    • Snir M, Lusky M, Shalev B, Gaton D, Weinberger D. 2000. Mitomycin C and 5-fluorouracil antimetabolite therapy for pediatric glaucoma filtration surgery. Ophthalmic Surg Lasers 31:31-37.
    • (2000) Ophthalmic Surg Lasers , vol.31 , pp. 31-37
    • Snir, M.1    Lusky, M.2    Shalev, B.3    Gaton, D.4    Weinberger, D.5
  • 46
    • 0033044686 scopus 로고    scopus 로고
    • A Fas-dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells
    • Tillman DM, Petak I, Houghton JA. 1999. A Fas-dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells. Clin Cancer Res 5:425-430.
    • (1999) Clin Cancer Res , vol.5 , pp. 425-430
    • Tillman, D.M.1    Petak, I.2    Houghton, J.A.3
  • 47
    • 0031981520 scopus 로고    scopus 로고
    • Recruitment and proliferative responses of osteoblasts after mechanical loading in vivo determined using sustained-release bromodeoxyuridine
    • Turner CH, Owan I, Alvey T, Hulman J, Hock JM. 1998. Recruitment and proliferative responses of osteoblasts after mechanical loading in vivo determined using sustained-release bromodeoxyuridine. Bone 22:463-469.
    • (1998) Bone , vol.22 , pp. 463-469
    • Turner, C.H.1    Owan, I.2    Alvey, T.3    Hulman, J.4    Hock, J.M.5
  • 50
    • 0042591173 scopus 로고    scopus 로고
    • Roles of growth factors in chemotherapy-induced intestinal mucosal damage repair
    • Xian CJ. 2003. Roles of growth factors in chemotherapy-induced intestinal mucosal damage repair. Curr Pharm Biotechnol 4:260-269.
    • (2003) Curr Pharm Biotechnol , vol.4 , pp. 260-269
    • Xian, C.J.1
  • 52
    • 0036196146 scopus 로고    scopus 로고
    • Effects of TGF-alpha gene knockout on epithelial cell kinetics and repair of methotrexate-induced damage in mouse small intestine
    • Xian CJ, Cool JC, Howarth GS, Read LC. 2002. Effects of TGF-alpha gene knockout on epithelial cell kinetics and repair of methotrexate-induced damage in mouse small intestine. J Cell Physiol 191:105-115.
    • (2002) J Cell Physiol , vol.191 , pp. 105-115
    • Xian, C.J.1    Cool, J.C.2    Howarth, G.S.3    Read, L.C.4
  • 53
    • 4344592584 scopus 로고    scopus 로고
    • Effects of acute 5-fluorouracil chemotherapy and insulin-like growth factor-I pretreatment on growth plate cartilage and metaphyseal bone in rats
    • Xian CJ, Howarth GS, Cool J, Foster BK. 2004a. Effects of acute 5-fluorouracil chemotherapy and insulin-like growth factor-I pretreatment on growth plate cartilage and metaphyseal bone in rats. Bone 35:739-749.
    • (2004) Bone , vol.35 , pp. 739-749
    • Xian, C.J.1    Howarth, G.S.2    Cool, J.3    Foster, B.K.4
  • 54
    • 0742301385 scopus 로고    scopus 로고
    • Intramembranous ossification mechanism for bone bridge formation at the growth plate cartilage injury site
    • Xian CJ, Zhou FH, McCarty RC, Foster BK. 2004b. Intramembranous ossification mechanism for bone bridge formation at the growth plate cartilage injury site. J Orthop Res 22:417-426.
    • (2004) J Orthop Res , vol.22 , pp. 417-426
    • Xian, C.J.1    Zhou, F.H.2    McCarty, R.C.3    Foster, B.K.4
  • 55
    • 0037338638 scopus 로고    scopus 로고
    • From mouse to man: Redefining the role of insulin-like growth factor-I in the acquisition of bone mass
    • (Maywood)
    • Yakar S, Rosen CJ. 2003. From mouse to man: Redefining the role of insulin-like growth factor-I in the acquisition of bone mass. Exp Biol Med (Maywood) 228:245-252.
    • (2003) Exp Biol Med , vol.228 , pp. 245-252
    • Yakar, S.1    Rosen, C.J.2
  • 56
    • 13844307612 scopus 로고    scopus 로고
    • Expression of proinflammatory cytokines and growth factors at the injured growth plate cartilage in young rats
    • Zhou FH, Foster BK, Sander G, Xian CJ. 2004. Expression of proinflammatory cytokines and growth factors at the injured growth plate cartilage in young rats. Bone 35:1307-1315.
    • (2004) Bone , vol.35 , pp. 1307-1315
    • Zhou, F.H.1    Foster, B.K.2    Sander, G.3    Xian, C.J.4
  • 57
    • 0031105952 scopus 로고    scopus 로고
    • Intensive chemotherapy using cisplatin and fluorouracil followed by radiotherapy in advanced head and neck cancer
    • Zidan J, Kuten A, Rosenblatt E, Robinson E. 1997. Intensive chemotherapy using cisplatin and fluorouracil followed by radiotherapy in advanced head and neck cancer. Oral Oncol 33:129-135.
    • (1997) Oral Oncol , vol.33 , pp. 129-135
    • Zidan, J.1    Kuten, A.2    Rosenblatt, E.3    Robinson, E.4


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