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Volumn 80, Issue 1, 2006, Pages 66-74

Modulation of cell cycle progression by CTLA4-CD80/CD86 interactions on CD4 + T cells depends on strength of the CD3 signal: Critical role for IL-2

Author keywords

Cell cycle progression; Costimulation; T cell activation

Indexed keywords

B7 ANTIGEN; CD3 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 2; TRANSFORMING GROWTH FACTOR BETA;

EID: 33751540126     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0505260     Document Type: Article
Times cited : (7)

References (29)
  • 1
    • 0036214017 scopus 로고    scopus 로고
    • The B7 family of ligands and its receptors, new pathways for costimulation and inhibition of immune responses
    • Carreno, B. M., Collins, M. (2002) The B7 family of ligands and its receptors, new pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 20, 29-53.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 29-53
    • Carreno, B.M.1    Collins, M.2
  • 2
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen, J. G., Kuhns, M. S., Allison, J. P. (2002) CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat. Immunol. 3, 611-618.
    • (2002) Nat. Immunol. , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 3
    • 0142259712 scopus 로고    scopus 로고
    • Unifying concepts in CD28, ICOS and CTLA4 co-receptor signaling
    • Rudd, C. E., Schneider, H. (2003) Unifying concepts in CD28, ICOS and CTLA4 co-receptor signaling. Nat. Rev. Immunol. 3, 544-556.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 544-556
    • Rudd, C.E.1    Schneider, H.2
  • 4
  • 5
    • 0036533515 scopus 로고    scopus 로고
    • Naïve CD4+ T cells exhibit distinct expression patterns of cytokines and cell surface molecules on their primary responses to varying doses of antigen
    • Ise, W., Totsuka, M., Sogawa, Y., Ametani, A., Hachimura, S., Sato, T., Kumagai, Y., Habu, S., Kaminogawa, S. (2002) Naïve CD4+ T cells exhibit distinct expression patterns of cytokines and cell surface molecules on their primary responses to varying doses of antigen. J. Immunol. 168, 3242-3250.
    • (2002) J. Immunol. , vol.168 , pp. 3242-3250
    • Ise, W.1    Totsuka, M.2    Sogawa, Y.3    Ametani, A.4    Hachimura, S.5    Sato, T.6    Kumagai, Y.7    Habu, S.8    Kaminogawa, S.9
  • 6
    • 0037120052 scopus 로고    scopus 로고
    • The proliferative capacity of individual naïve CD4+ T cells is amplified by prolonged T cell antigen receptor triggering
    • Schrum, A. G., Turka, L. A. (2002) The proliferative capacity of individual naïve CD4+ T cells is amplified by prolonged T cell antigen receptor triggering. J. Exp. Med. 196, 793-803.
    • (2002) J. Exp. Med. , vol.196 , pp. 793-803
    • Schrum, A.G.1    Turka, L.A.2
  • 8
    • 0036172220 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength
    • Egen, J. G., Allison, J. P. (2002) Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength. Immunity 16, 23-35.
    • (2002) Immunity , vol.16 , pp. 23-35
    • Egen, J.G.1    Allison, J.P.2
  • 9
    • 0029120245 scopus 로고
    • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
    • Krummel, M. F., Allison, J. P. (1995) CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182, 459-465.
    • (1995) J. Exp. Med. , vol.182 , pp. 459-465
    • Krummel, M.F.1    Allison, J.P.2
  • 10
    • 0032538819 scopus 로고    scopus 로고
    • Engagement of cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) induces transforming growth factor β (TGFβ) production by murine CD4+ T cells
    • Chen, W., Jin, W., Wahl, S. M. (1998) Engagement of cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) induces transforming growth factor β (TGFβ) production by murine CD4+ T cells. J. Exp. Med. 188, 1849-1857.
    • (1998) J. Exp. Med. , vol.188 , pp. 1849-1857
    • Chen, W.1    Jin, W.2    Wahl, S.M.3
  • 12
    • 0035865522 scopus 로고    scopus 로고
    • CTLA4 blockade of antigen induced cell death
    • da Rocha Dias, S., Rudd, C. E. (2001) CTLA4 blockade of antigen induced cell death. Blood 97, 1134-1137.
    • (2001) Blood , vol.97 , pp. 1134-1137
    • Da Rocha Dias, S.1    Rudd, C.E.2
  • 13
    • 0036853575 scopus 로고    scopus 로고
    • Role of CD80, CD86 and CTLA4 on mouse CD4+ T lymphocytes in enhancing cell cycle progression and survival after activation with PMA and ionomycin
    • Mukherjee, S., Maiti, P. K., Nandi, D. (2002) Role of CD80, CD86 and CTLA4 on mouse CD4+ T lymphocytes in enhancing cell cycle progression and survival after activation with PMA and ionomycin. J. Leukoc. Biol. 72, 921-931.
    • (2002) J. Leukoc. Biol. , vol.72 , pp. 921-931
    • Mukherjee, S.1    Maiti, P.K.2    Nandi, D.3
  • 14
    • 1642305625 scopus 로고    scopus 로고
    • CD152 (CTLA4) determines the unequal resistance of Th1 and Th2 cells against activation induced cell death by a mechanism requiring PI3 kinase function
    • Pandiyan, P., Gärtner, D., Soezeri, O., Radbruch, A., Schulze-Osthoff, K., Brunner-Weinzierl, M. C. (2004) CD152 (CTLA4) determines the unequal resistance of Th1 and Th2 cells against activation induced cell death by a mechanism requiring PI3 kinase function. J. Exp. Med. 199, 831-842.
    • (2004) J. Exp. Med. , vol.199 , pp. 831-842
    • Pandiyan, P.1    Gärtner, D.2    Soezeri, O.3    Radbruch, A.4    Schulze-Osthoff, K.5    Brunner-Weinzierl, M.C.6
  • 17
    • 0033964373 scopus 로고    scopus 로고
    • Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population
    • Anderson, D. E., Bieganowska, K. D., Bar-Or, A., Oliveira, E. M. L., Carreno, B., Collins, M., Hafler, D. A. (2000) Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population. Nat. Med. 6, 211-214.
    • (2000) Nat. Med. , vol.6 , pp. 211-214
    • Anderson, D.E.1    Bieganowska, K.D.2    Bar-Or, A.3    Oliveira, E.M.L.4    Carreno, B.5    Collins, M.6    Hafler, D.A.7
  • 18
    • 0033731186 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells
    • Kuhns, M. S., Epshteyn, V., Sobel, R. A., Allison, J. P. (2000) Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells. Proc. Natl. Acad. Sci. USA 97, 12711-12716.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12711-12716
    • Kuhns, M.S.1    Epshteyn, V.2    Sobel, R.A.3    Allison, J.P.4
  • 19
    • 2442552882 scopus 로고    scopus 로고
    • Conversion of CTLA4 from inhibitor to activator of T cells with a bispecific tandem single chain Fv ligand
    • Madrenas, J., Chau, L. A., Teft, W. A., Wu, P. W., Jussif, J., Kasaian, M., Carreno, B. M., Ling, V. (2004) Conversion of CTLA4 from inhibitor to activator of T cells with a bispecific tandem single chain Fv ligand. J. Immunol. 172, 5948-5956.
    • (2004) J. Immunol. , vol.172 , pp. 5948-5956
    • Madrenas, J.1    Chau, L.A.2    Teft, W.A.3    Wu, P.W.4    Jussif, J.5    Kasaian, M.6    Carreno, B.M.7    Ling, V.8
  • 20
    • 9144227496 scopus 로고    scopus 로고
    • Role of CTLA4 in the activation of single and double positive thymocytes
    • Kwon, H., Jun, H-S., Khil, L-Y., Yoon, J-W. (2004) Role of CTLA4 in the activation of single and double positive thymocytes. J. Immunol. 173, 6645-6653.
    • (2004) J. Immunol. , vol.173 , pp. 6645-6653
    • Kwon, H.1    Jun, H.-S.2    Khil, L.-Y.3    Yoon, J.-W.4
  • 21
    • 22144476493 scopus 로고    scopus 로고
    • CTLA4-CD80/CD86 interactions on primary mouse CD4+ T cells integrate signal-strength information to modulate activation with Concanavalin A
    • Mukherjee, S., Ahmed, A., Nandi, D. (2005) CTLA4-CD80/CD86 interactions on primary mouse CD4+ T cells integrate signal-strength information to modulate activation with Concanavalin A. J. Leukoc. Biol. 78, 144-157.
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 144-157
    • Mukherjee, S.1    Ahmed, A.2    Nandi, D.3
  • 22
    • 0031573078 scopus 로고    scopus 로고
    • Expression of a hypoglycosylated form of CD86 (B7.2) on human T cells with altered binding properties to CD28 and CTLA4
    • Höllsberg, P., Scholz, C., Anderson, D. E., Greenfield, E. A., Kuchroo, V. K., Freeman, G. J., Hafler, D. A. (1997) Expression of a hypoglycosylated form of CD86 (B7.2) on human T cells with altered binding properties to CD28 and CTLA4. J. Immunol. 159, 4799-4805.
    • (1997) J. Immunol. , vol.159 , pp. 4799-4805
    • Höllsberg, P.1    Scholz, C.2    Anderson, D.E.3    Greenfield, E.A.4    Kuchroo, V.K.5    Freeman, G.J.6    Hafler, D.A.7
  • 24
  • 26
    • 0027156266 scopus 로고
    • Anti-CD3-stimulated Ca+2 signal in individual human peripheral T cells
    • Wacholtz, M. C., Lipsky, P. E. (1993) Anti-CD3-stimulated Ca+2 signal in individual human peripheral T cells. J. Immunol. 150, 5338-5349.
    • (1993) J. Immunol. , vol.150 , pp. 5338-5349
    • Wacholtz, M.C.1    Lipsky, P.E.2
  • 27
    • 0032708754 scopus 로고    scopus 로고
    • Stimulating naïve T cells
    • Sprent, J. (1999) Stimulating naïve T cells. J. Immunol. 163, 4629-4636.
    • (1999) J. Immunol. , vol.163 , pp. 4629-4636
    • Sprent, J.1
  • 28
    • 0027515034 scopus 로고
    • Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human γ1
    • Lane, P., Gerhard, W., Hubele, S., Lanzavecchia, A., McConnell, F. (1993) Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human γ1. Immunology 80, 56-61.
    • (1993) Immunology , vol.80 , pp. 56-61
    • Lane, P.1    Gerhard, W.2    Hubele, S.3    Lanzavecchia, A.4    McConnell, F.5
  • 29
    • 0033023432 scopus 로고    scopus 로고
    • Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands
    • Murtaza, A., Kuchroo, V. K., Freeman, G. J. (1999) Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands. Int. Immunol. 11, 407-416.
    • (1999) Int. Immunol. , vol.11 , pp. 407-416
    • Murtaza, A.1    Kuchroo, V.K.2    Freeman, G.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.