Herpes-simplex virus encephalitis is characterized by an early MMP-9 increase and collagen type IV degradation

Brain Research

Volumn 1125, Issue 1, 2006, Pages 155-162

  Sellner, Johann ^a,c   Simon, Franziska ^c   Meyding Lamade, Uta ^b   Leib, Stephen L ^c  

^a UNIVERSITY OF BERN   (Switzerland)

^b KRANKENHAUS NORDWEST   (Germany)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Blood brain barrier; Brain injury; Collagen type IV; Herpes simplex virus encephalitis; Matrix metalloproteinase; Neuroinfection; Neuroinflammation

Indexed keywords

COLLAGEN TYPE 4; GELATINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN REGION; COLLAGEN DEGRADATION; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS 1; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; ZYMOGRAPHY;

ANIMALS; BLOTTING, WESTERN; COLLAGEN TYPE IV; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENCEPHALITIS, HERPES SIMPLEX; FEMALE; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MATRIX METALLOPROTEINASE 2; MICE; TIME FACTORS; VIRAL LOAD;

SIMPLEXVIRUS;

EID: 33751504327     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.09.093     Document Type: Article

References (35)

1. Arsenio-Nunes M.L., Cerutti I., and Farkas-Bargeton E. Vascular and neuroglial changes in experimental herpes simplex encephalitis: ultrastructural study. Acta Neuropathol. (Berl) 33 3 (1975) 245-256
2. Asahi M., Wang X., Mori T., Sumii T., Jung J.C., Moskowitz M.A., Fini M.E., and Lo E.H. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J. Neurosci. 21 19 (2001) 7724-7732
3. Barnett G.H., Ropper A.H., and Romeo J. Intracranial pressure and outcome in adult encephalitis. J. Neurosurg. 68 4 (1988) 585-588
4. Beuche W., Yushchenko M., Mader M., Maliszewska M., Felgenhauer K., and Weber F. Matrix metalloproteinase-9 is elevated in serum of patients with amyotrophic lateral sclerosis. NeuroReport 11 16 (2000) 3419-3422
5. Chan W.L., Javanovic T., and Lukic M.L. Infiltration of immune T cells in the brain of mice with herpes simplex virus-induced encephalitis. J. Neuroimmunol. 23 3 (1989) 195-201
6. Cunningham L.A., Wetzel M., and Rosenberg G.A. Multiple roles for MMPs and TIMPs in cerebral ischemia. Glia 50 4 (2005) 329-339
7. Esiri M.M., Drummond C.W., and Morris C.S. Macrophages and microglia in HSV-1 infected mouse brain. J. Neuroimmunol. 62 2 (1995) 201-205
8. Esiri M.M., Reading M.C., Squier M.V., and Hughes J.T. Immunocytochemical characterization of the macrophage and lymphocyte infiltrate in the brain in six cases of human encephalitis of varied aetiology. Neuropathol. Appl. Neurobiol. 15 4 (1989) 289-305
9. Farkas-Bargeton E., Diebler M.F., Kristensson K., Lycke E., and Sourander P. Vascular and neuroglial changes in experimental herpes simplex encephalitis enzyme histochemical study. Acta Neuropathol. (Berl) 33 1 (1975) 51-57
10. Galis Z.S., and Khatri J.J. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ. Res. 90 3 (2002) 251-262
11. Gasche Y., Soccal P.M., Kanemitsu M., and Copin J.C. Matrix metalloproteinases and diseases of the central nervous system with a special emphasis on ischemic brain. Front. Biosci. 11 (2006) 1289-1301
12. Horstmann S., Kalb P., Koziol J., Gardner H., and Wagner S. Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients: influence of different therapies. Stroke 34 9 (2003) 2165-2170
13. Hudson S.J., Dix R.D., and Streilein J.W. Induction of encephalitis in SJL mice by intranasal infection with herpes simplex virus type 1: a possible model of herpes simplex encephalitis in humans. J. Infect. Dis. 163 4 (1991) 720-727
14. Kamei S., Sekizawa T., Shiota H., Mizutani T., Itoyama Y., Takasu T., Morishima T., and Hirayanagi K. Evaluation of combination therapy using aciclovir and corticosteroid in adult patients with herpes simplex virus encephalitis. J. Neurol., Neurosurg. Psychiatry 76 11 (2005) 1544-1549
15. Kleinschmidt-DeMasters B.K., and Gilden D.H. The expanding spectrum of herpesvirus infections of the nervous system. Brain Pathol. 11 4 (2001) 440-451
16. Kolb S.A., Lahrtz F., Paul R., Leppert D., Nadal D., Pfister H.W., and Fontana A. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in viral meningitis: upregulation of MMP-9 and TIMP-1 in cerebrospinal fluid. J. Neuroimmunol. 84 2 (1998) 143-150
17. Leib S.L., Leppert D., Clements J., and Täuber M.G. Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis. Infect. Immun. 68 2 (2000) 615-620
18. Leppert D., Leib S.L., Grygar C., Miller K.M., Schaad U.B., and Hollander G.A. Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae. Clin. Infect. Dis. 31 1 (2000) 80-84
19. Lo E.H., Wang X., and Cuzner M.L. Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases. J. Neurosci. Res. 69 1 (2002) 1-9
20. Lokensgard J.R., Cheeran M.C., Hu S., Gekker G., and Peterson P.K. Glial cell responses to herpesvirus infections: role in defense and immunopathogenesis. J. Infect. Dis. 186 Suppl. 2 (2002) S171-S179
21. Martinez-Torres F.J., Wagner S., Haas J., Kehm R., Sellner J., Hacke W., and Meyding-Lamade U. Increased presence of matrix metalloproteinases 2 and 9 in short- and long-term experimental herpes simplex virus encephalitis. Neurosci. Lett. 368 3 (2004) 274-278
22. Meyding-Lamade U., Haas J., Lamade W., Stingele K., Kehm R., Fath A., Heinrich K., Storch Hagenlocher B., and Wildemann B. Herpes simplex virus encephalitis: long-term comparative study of viral load and the expression of immunologic nitric oxide synthase in mouse brain tissue. Neurosci. Lett. 244 1 (1998) 9-12
23. Meyding-Lamade U., Lamade W., Kehm R., Knopf K.W., Hess T., Gosztonyi G., Degen O., and Hacke W. Herpes simplex virus encephalitis: cranial magnetic resonance imaging and neuropathology in a mouse model. Neurosci. Lett. 248 1 (1998) 13-16
24. Raschilas F., Wolff M., Delatour F., Chaffaut C., De Broucker T., Chevret S., Lebon P., Canton P., and Rozenberg F. Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin. Infect. Dis. 35 3 (2002) 254-260
25. Rosenberg G.A., and Navratil M. Metalloproteinase inhibition blocks edema in intracerebral hemorrhage in the rat. Neurology 48 4 (1997) 921-926
26. Rosenberg G.A., Dencoff J.E., Correa Jr. N., Reiners M., and Ford C.C. Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood-brain barrier injury. Neurology 46 6 (1996) 1626-1632
27. Rosler A., Pohl M., Braune H.J., Oertel W.H., Gemsa D., and Sprenger H. Time course of chemokines in the cerebrospinal fluid and serum during herpes simplex type 1 encephalitis. J. Neurol. Sci. 157 1 (1998) 82-89
28. Seguin R., Biernacki K., Rotondo R.L., Prat A., and Antel J.P. Regulation and functional effects of monocyte migration across human brain-derived endothelial cells. J. Neuropathol. Exp. Neurol. 62 4 (2003) 412-419
29. Sellner J., and Leib S.L. In bacterial meningitis cortical brain damage is associated with changes in parenchymal MMP-9/TIMP-1 ratio and increased collagen type IV degradation. Neurobiol. Dis. 21 3 (2006) 647-656
30. Sellner J., Dvorak F., Zhou Y., Haas J., Kehm R., Wildemann B., and Meyding-Lamade U. Acute and long-term alteration of chemokine mRNA expression after anti-viral and anti-inflammatory treatment in herpes simplex virus encephalitis. Neurosci. Lett. 374 3 (2005) 197-202
31. Sobel R.A., Collins A.B., Colvin R.B., and Bhan A.K. The in situ cellular immune response in acute herpes simplex encephalitis. Am. J. Pathol. 125 2 (1986) 332-338
32. Waubant E., Goodkin D.E., Gee L., Bacchetti P., Sloan R., Stewart T., Andersson P.B., Stabler G., and Miller K. Serum MMP-9 and TIMP-1 levels are related to MRI activity in relapsing multiple sclerosis. Neurology 53 7 (1999) 1397-1401
33. Whitley R.J., and Roizman B. Herpes simplex virus infections. Lancet 357 9267 (2001) 1513-1518
34. Zhou J., Marten N.W., Bergmann C.C., Macklin W.B., Hinton D.R., and Stohlman S.A. Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis. J. Virol. 79 8 (2005) 4764-4773
35. Zhang J.W., and Gottschall P.E. Zymographic measurement of gelatinase activity in brain tissue after detergent extraction and affinity-support purification. J. Neurosci. Methods 76 1 (1997) 15-20