Herpes simplex virus encephalitis: Long-term comparative study of viral load and the expression of immunologic nitric oxide synthase in mouse brain tissue

Neuroscience Letters

Volumn 244, Issue 1, 1998, Pages 9-12

  Meyding Lamadé, Uta ^a   Haas, Jürgen ^a   Lamadé, Wolfram ^a   Stingele, Karoline ^a   Kehm, Roland ^a   Fäth, Almut ^a   Heinrich, Katja ^a   Storch Hagenlocher, Brigitte ^a   Wildemann, Brigitte ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Herpes encephalitis; Herpes simplex virus; Nitric oxide synthase; Viral burden

Indexed keywords

NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; FEMALE; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS; MOUSE; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS LOAD;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; ENCEPHALITIS, VIRAL; FEMALE; HERPES SIMPLEX; MICE; MICE, INBRED STRAINS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; SIMPLEXVIRUS; VIRAL LOAD;

EID: 0032489541     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00115-3     Document Type: Article

References (18)

1. Adamson D.C., Wildemann B., Sasaki M., Glass J.D., McArthur J.C., Christov V.I., Dawson T.M., Dawson V.L. Immunologic NO-synthase: evaluation in severe AIDS dementia and induction by HIV-1 gp41. Science. 274:1996;1917-1921.
2. Ando Y., Kimura H., Miwata H., Kudo T., Shibata M., Morishima T. Quantitative analysis of herpes simplex virus DNA in cerebrospinal fluid of children with herpes simplex encephalitis. J. Med. Virol. 41:1993;170-173.
3. Bö L., Dawson T.M., Wesselingh S., Mork S., Choi S., Kong P.A., Hanley D., Trapp B.D. Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann. Neurol. 36:1994;778-786.
4. Boje K.M., Arora P.K. Microglial produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res. 587:1992;250-256.
5. Bonofoco E., Krainc E., Ankacrona D.M., Nicotera P., Lipton S.A. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric/superoxide in cortical cell cultures. Proc. Natl. Acad. Sci. USA. 92:1995;7162-7166.
6. Chao C.C., Hu S., Molitor T.W., Shaskar E.G., Peterson P.K. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J. Immunol. 149:1992;2736-2741.
7. Darai, G., Scholz, J., Kurz, W. and Koch, H.G., Herpes virus of man and animal: standardization of immunological procedures. In M. Bonneau and W. Hennessen (Eds.), Developments in Biological Standardization, Karger, München, 1982, pp. 67-80.
8. Hudson S.J., Dix R.D., Streilein J.W. Induction of encephalitis in SJL mice by intranasal infection with herpes simplex type 1: a possible model of herpes simplex encephalitis in humans. J. Infect. Dis. 163:1991;720-727.
9. Iadecola C., Zhang F., Xu X. Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am. J. Physiol. 268:1995;286-292.
10. Koprowski H., Zheng Y.M., Heber-Katz E., Fraser N., Rorke L., Fu Z.F., Hanlon C., Dietschold B. In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases. Proc. Natl. Acad. Sci. USA. 90:1993;3024-3027.
11. Meyding-Lamadé U., Lamadé W., Heß T., Gosztonyi G., Kehm R., Sartor K., Hacke W. A mouse model of herpes simplex virus encephalitis: diagnostic brain imaging by magnetic resonance imaging. J. Int. In Vivo Res. 10:1996;563-568.
12. Nahmias, A.J., Whitley, R.J., Visintine, A.N., Takei, Y., Alford, C.A., Jr. and the collaborative antiviral study group, Herpes simplex encephalitis: laboratory evaluations and their diagnostic significance, J. Infect. Dis., 145 (1982) 829-836.
13. Sköldenberg B., Alestig K., Bergström T., Burmann L., Dahlquist E., Forkmann A., Fryden A., Lovgren K., Norlin K. Acyclovir versus vidarabine in herpes simplex encephalitis: randomised multicentre study in consecutive Swedish patients. Lancet. 2:1984;707-711.
14. Steuler H., Munzinger S., Wildemann B., StorchHagenlocher B. Quantitation of HIV-1 proviral DNA in cells from cerebrospinal fluid. J. Acquired Immune Defic. Syndr. 5:1992;405-408.
15. Suschek C., Rothe H., Fehsel K., Enczmann J., Kolb-Bachofen V. Induction of a macrophage-like nitric oxide synthase in cultured rat aortic endothelial cells. II-1β-mediated induction regulated by tumour necrosis factor- and INF-γ J. Immunol. 151:1993;3283-3291.
16. Whitley, R.J. and Schlitt, M., Encephalitis caused by herpes viruses, including B virus. In W.M. Schield, R.J. Whitley and D.T. Durack (Eds.), Infections of the Central Nervous System, Raven, New York, 1991, pp. 41-86.
17. Wildemann B., Ehrhart K., Storch-Hagenlocher B., Meyding-Lamadé U., Steinvorth S., Hacke W., Haas J. Quantitation of herpes simplex virus type 1 DNA in cells of cerebrospinal fluid of patients with herpes simplex virus encephalitis. Neurology. 48:1997;1341-1346.
18. Zheng Y.M., Schäfer M.K., Weihe E., Sheng H., Corisdeo S., Fu Z.F., Koprowski H., Dietschold B. Severity of neurological signs and degree of inflammatory lesions in the brains of rats with Borna disease correlate with the induction of nitric oxide synthase. J. Virol. 67:1993;5786-5791.