Mathematical assessment of properties of precursor-dependent indirect pharmacodynamic response models

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 33, Issue 6, 2006, Pages 683-717

  Hazra, Anasuya ^a   Krzyzanski, Wojciech ^a   Jusko, William J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Indirect response; Perturbation theory; Precursor pool; Tolerance

Indexed keywords

AREA UNDER THE CURVE; ARTICLE; COMPUTER SIMULATION; DOSE RESPONSE; DRUG EFFICACY; DRUG MEGADOSE; DRUG QUALITY; DRUG TOLERANCE; IC 50; MATHEMATICAL MODEL; PHARMACODYNAMICS; PHARMACOLOGICAL PARAMETERS; PRECURSOR; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; REBOUND; THEORETICAL MODEL;

AREA UNDER CURVE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; MATHEMATICS; MODELS, THEORETICAL; PRODRUGS;

EID: 33751422322     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-006-9030-4     Document Type: Article

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