Effects of TRIM on tension, intracellular calcium and nitrergic transmission in the rat anococcygeus muscle

Nitric Oxide - Biology and Chemistry

Volumn 16, Issue 1, 2007, Pages 29-35

  Che, Yan ^a   Potocnik, Simon ^a   Ellis, Anthie ^a   Li, Chun Guang ^a  

^a RMIT UNIVERSITY   (Australia)

Author keywords

1 (2 Trifluoromethylphenyl) imidazole (TRIM); Anococcygeus muscle (rat); Intracellular calcium ions Ca2+ i; Nitrergic relaxation; Nitric oxide synthase; Tension

Indexed keywords

1 (2 TRIFLUOROMETHYLPHENYL)IMIDAZOLE; CALCIUM; CLONIDINE; GUANETHIDINE; GUANYLATE CYCLASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN; PHENYLEPHRINE; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL TISSUE; ANOCOCCYGEUS MUSCLE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; ELECTRIC FIELD; ENZYME INHIBITION; IC 50; MALE; MEMBRANE CURRENT; MUSCLE CONTRACTILITY; MUSCLE TONE; NITRERGIC NERVE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER MEMBRANE POTENTIAL;

ANIMALS; CALCIUM; ELECTRIC STIMULATION; IMIDAZOLES; MALE; MUSCLE, SMOOTH; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33751396960     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2006.05.001     Document Type: Article

References (24)

1. Handy R.L., and Moore P.K. Mechanism of the inhibition of neuronal nitric oxide synthase by 1-(2-trifluoromethylphenyl) imidazole (TRIM). Life Sci. 60 (1997) L389-L394
2. Handy R.L., Wallace P., Gaffen Z.A., Whitehead K.J., and Moore P.K. The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse. Br. J. Pharmacol. 116 (1995) 2349-2350
3. Handy R.L., Harb H.L., Wallace P., Gaffen Z., Whitehead K.J., and Moore P.K. Inhibition of nitric oxide synthase by 1-(2-trifluoromethylphenyl) imidazole (TRIM) in vitro: antinociceptive and cardiovascular effects. Br. J. Pharmacol. 119 (1996) 423-431
4. Guilmard C., Auguet M., and Chabrier P.E. Comparison between endothelial and neuronal nitric oxide pathways in rat aorta and gastric fundus. Nitric Oxide 2 (1998) 147-154
5. Lamping K.G., Nuno D.W., Shesely E.G., Maeda N., and Faraci F.M. Vasodilator mechanisms in the coronary circulation of endothelial nitric oxide synthase-deficient mice. Am. J. Physiol. Heart Circ. Physiol. 279 (2000) H1906-H1912
6. Escott K.J., Beech J.S., Haga K.K., Williams S.C., Meldrum B.S., and Bath P.M. Cerebroprotective effect of the nitric oxide synthase inhibitors, 1-(2-trifluoromethylphenyl) imidazole and 7-nitro indazole, after transient focal cerebral ischemia in the rat. J. Cereb. Blood Flow Metab. 18 (1998) 281-287
7. Sweeney C., and Markos F. The role of neuronal nitric oxide in the vagal control of cardiac interval of the rat heart in vitro. Auton. Neurosci. 111 (2004) 110-115
8. Salgado M.C.O., Justo S.V., Joaquim L.F., Fazan Jr. R., and Salgado H.C. Role of nitric oxide and prostanoids in the attenuation of rapid baroreceptor resetting. Am. J. Physiol. Heart Circ. Physiol. 290 (2005) H1059-H1063
9. Gibson A., Fernandes F., Wallace P., and McFadzean I. Selective inhibition of thapsigargin-induced contraction and capacitative calcium entry in mouse anococcygeus by trifluoromethylphenylimidazole (TRIM). Br. J. Pharmacol. 134 (2001) 233-236
10. Teixeira C.E., Bento A.C., Lopes-Martins R.A., Teixeira S.A., vonEickestedt V., Muscara M.N., Arantes E.C., Giglio J.R., Antunes E., and de Nucci G. Effect of Tityus serrulatus scorpion venom on the rabbit isolated corpus cavernosum and the involvement of NANC nitrergic nerve fibres. Br. J. Pharmacol. 123 (1998) 435-442
11. Chaban V.V., McRoberts J.A., Ennes H.S., and Mayer E.A. Nitric oxide synthase inhibitors enhance mechanosensitive Ca(2+) influx in cultured dorsal root ganglion neurons. Brain Res. 903 (2001) 74-85
12. Gillespie J.S. The rat anococcygeus muscle and its response to nerve stimulation and to some drugs. Br. J. Pharmacol. 45 (1972) 404-416
13. Li C.G., and Rand M.J. Evidence for a role of nitric oxide in the neurotransmitter system mediating relaxation of the rat anococcygeus muscle. Clin. Exp. Pharmacol. Physiol. 16 (1989) 933-938
14. Rand M.J. Nitrergic transmission: nitric oxide as a mediator of non-adrenergic, non-cholinergic neuro-effector transmission. Clin. Exp. Pharmacol. Physiol. 19 (1992) 147-169
15. Rand M.J., and Li C.G. Nitric oxide as a neurotransmitter in peripheral nerves: nature of transmitter and mechanism of transmission. Annu. Rev. Physiol. 57 (1995) 659-682
16. Iravani M.M., and Zar M.A. Differential effects of nifedipine on nerve-mediated and noradrenaline-evoked contractions of rat anococcygeus muscle. Eur. J. Pharmacol. 250 (1993) 193-195
17. 2+ sources mobilized by alpha 1-receptor activation in vascular smooth muscle. Clin. Sci. (Lond.) 68 (1985) 47S-50S
18. c subunit. Br. J. Pharmacol. 129 (2000) 547-554
19. 2+ influx in smooth muscle cells from mouse anococcygeus. Eur. J. Pharmacol. 376 (1999) 325-329
20. Wallace P., Ayman S., McFadzean I., and Gibson A. Thapsigargin-induced tone and capacitative calcium influx in mouse anococcygeus smooth muscle cells. Naunyn. Schmiedebergs Arch. Pharmacol. 360 (1999) 368-375
21. McFadzean I., and Gibson A. The developing relationship between receptor-operated and store-operated calcium channels in smooth muscle. Br. J. Pharmacol. 135 (2002) 1-13
22. da Silva C., and Bendhack L.M. Thapsigargin does not affect phenylephrine-induced contractions in the anococcygeus muscle of rats. Gen. Pharmacol. 29 (1997) 257-260
23. Chakder S., and Rattan S. Mechanisms and sites of action of endothelins 1 and 2 on the opossum internal anal sphincter smooth muscle tone in vitro. J. Pharmacol. Exp. Ther. 288 (1999) 239-246
24. Vinh V.H., Enoki T., Hirata S., Toda H., Kakkuyama M., Nakamura K., and Fukuda K. Comparative contractile effects of halothane and sevoflurane in rat aorta. Anesthesiology 92 (2000) 219-227