메뉴 건너뛰기




Volumn 27, Issue 5, 2006, Pages 215-220

Proteasome inhibition as a new therapeutic concept;Proteasominhibition als neues therapiekonzept

Author keywords

Bortezomib; Cell cycle; Multiple myeloma; Proteasome inhibition; Ubiquitin

Indexed keywords

ANTINEOPLASTIC AGENT; BORTEZOMIB; PROTEASOME; PROTEASOME INHIBITOR; UBIQUITIN;

EID: 33751345587     PISSN: 0722219X     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-926986     Document Type: Review
Times cited : (1)

References (33)
  • 1
    • 11244309014 scopus 로고    scopus 로고
    • Proteolysis: From the lysosome to ubiquitin and the proteasome
    • Ciechanover A. Proteolysis: from the lysosome to ubiquitin and the proteasome. Nat Rev Mol Cell Biol 2005; 6: 79-87
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 79-87
    • Ciechanover, A.1
  • 2
    • 2342613652 scopus 로고    scopus 로고
    • The proteasome: A suitable antineoplastic target
    • Adams J. The proteasome: a suitable antineoplastic target. Nat Rev Cancer 2004; 4: 349-360
    • (2004) Nat Rev Cancer , vol.4 , pp. 349-360
    • Adams, J.1
  • 3
    • 0347815503 scopus 로고    scopus 로고
    • Single versus double autologous stem-cell transplantation for multiple myeloma
    • Attal M, Harousseau JL, Facon T et al. Single versus double autologous stem-cell transplantation for multiple myeloma. N Engl J Med 2003; 349: 2495-2502
    • (2003) N Engl J Med , vol.349 , pp. 2495-2502
    • Attal, M.1    Harousseau, J.L.2    Facon, T.3
  • 4
    • 33646401089 scopus 로고    scopus 로고
    • Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma
    • Garban F, Attal M, Michallet M et al. Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma. Blood 2006; 107: 3474-3480
    • (2006) Blood , vol.107 , pp. 3474-3480
    • Garban, F.1    Attal, M.2    Michallet, M.3
  • 5
    • 31744434280 scopus 로고    scopus 로고
    • Efficacy of diverse high-dose regimens followed by autologous peripheral blood stem cell transplantation in consecutive multiple myeloma patients: A single-centre analysis over a 12-year period
    • Haas PS, Bauchmüller K, Kühnemund A et al. Efficacy of diverse high-dose regimens followed by autologous peripheral blood stem cell transplantation in consecutive multiple myeloma patients: a single-centre analysis over a 12-year period. Ann Hematol 2006; 85: 191-193
    • (2006) Ann Hematol , vol.85 , pp. 191-193
    • Haas, P.S.1    Bauchmüller, K.2    Kühnemund, A.3
  • 6
    • 0029564960 scopus 로고
    • Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells
    • Imajoh-Ohmi S, Kawaguchi T, Sugiyama S et al. Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells. Biochem Biophys Res Commun 1995; 217: 1070-1077
    • (1995) Biochem Biophys Res Commun , vol.217 , pp. 1070-1077
    • Imajoh-Ohmi, S.1    Kawaguchi, T.2    Sugiyama, S.3
  • 7
    • 0032189685 scopus 로고    scopus 로고
    • Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor
    • Orlowski RZ, Eswara JR, Lafond-Walker A et al. Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor. Cancer Res 1998; 58: 4342-4348
    • (1998) Cancer Res , vol.58 , pp. 4342-4348
    • Orlowski, R.Z.1    Eswara, J.R.2    Lafond-Walker, A.3
  • 8
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T, Richardson P, Chauhan D et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 2001; 61: 3071-3076
    • (2001) Cancer Res , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3
  • 9
    • 0037111832 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
    • Orlowski RZ, Stinchcombe TE, Mitchell BS et al. Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J Clin Oncol 2002; 20: 4420-4427
    • (2002) J Clin Oncol , vol.20 , pp. 4420-4427
    • Orlowski, R.Z.1    Stinchcombe, T.E.2    Mitchell, B.S.3
  • 10
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson PG, Barlogie B, Berenson J et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003; 348: 2609-2617
    • (2003) N Engl J Med , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 11
    • 5644250621 scopus 로고    scopus 로고
    • A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma
    • Jagannath S, Barlogie B, Berenson J et al. A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. Br J Haematol 2004; 127: 165-172
    • (2004) Br J Haematol , vol.127 , pp. 165-172
    • Jagannath, S.1    Barlogie, B.2    Berenson, J.3
  • 12
    • 18644372165 scopus 로고    scopus 로고
    • Severe irreversible bilateral hearing loss after bortezomib (VELCADE) therapy in a multiple myeloma (MM) patient
    • Engelhardt M, Muller AM, Maier W et al. Severe irreversible bilateral hearing loss after bortezomib (VELCADE) therapy in a multiple myeloma (MM) patient. Leukemia 2005; 19: 869-870
    • (2005) Leukemia , vol.19 , pp. 869-870
    • Engelhardt, M.1    Muller, A.M.2    Maier, W.3
  • 13
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    • Richardson PG, Sonneveld P, Schuster MW et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 2005; 352: 2487-2498
    • (2005) N Engl J Med , vol.352 , pp. 2487-2498
    • Richardson, P.G.1    Sonneveld, P.2    Schuster, M.W.3
  • 14
    • 33746332717 scopus 로고    scopus 로고
    • Bortezomib continues to demonstrate superior efficacy compared with high-dose dexamethasone in relapsed multiple myeloma: Updated results of the APEX trial
    • Richardson P, Sonneveld P, Schuster M et al. Bortezomib continues to demonstrate superior efficacy compared with high-dose dexamethasone in relapsed multiple myeloma: updated results of the APEX trial. Blood 2005; 106: 715a
    • (2005) Blood , vol.106
    • Richardson, P.1    Sonneveld, P.2    Schuster, M.3
  • 15
    • 20444455939 scopus 로고    scopus 로고
    • Bortezomib for myeloma - Much ado about something
    • Dispenzieri A. Bortezomib for myeloma - much ado about something. N Engl J Med 2005; 352: 2546-2548
    • (2005) N Engl J Med , vol.352 , pp. 2546-2548
    • Dispenzieri, A.1
  • 16
    • 21344469223 scopus 로고    scopus 로고
    • Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma
    • Jagannath S, Durie BG, Wolf J et al. Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma. Br J Haematol 2005; 129: 776-783
    • (2005) Br J Haematol , vol.129 , pp. 776-783
    • Jagannath, S.1    Durie, B.G.2    Wolf, J.3
  • 17
    • 20144387627 scopus 로고    scopus 로고
    • Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
    • Orlowski RZ, Voorhees PM, Garcia RA et al. Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 2005; 105: 3058-3065
    • (2005) Blood , vol.105 , pp. 3058-3065
    • Orlowski, R.Z.1    Voorhees, P.M.2    Garcia, R.A.3
  • 18
    • 21344435052 scopus 로고    scopus 로고
    • PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma
    • Oakervee HE, Popat R, Curry N et al. PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma. Br J Haematol 2005; 129: 755-762
    • (2005) Br J Haematol , vol.129 , pp. 755-762
    • Oakervee, H.E.1    Popat, R.2    Curry, N.3
  • 19
    • 33645662389 scopus 로고    scopus 로고
    • Rapid control of previously untreated multiple myeloma with bortezomib-thalidomide-dexamethasone followed by early intensive therapy
    • Wang M, Delasalle K, Giralt S et al. Rapid control of previously untreated multiple myeloma with bortezomib-thalidomide-dexamethasone followed by early intensive therapy. Blood 2005; 106: 231a
    • (2005) Blood , vol.106
    • Wang, M.1    Delasalle, K.2    Giralt, S.3
  • 20
    • 33744803947 scopus 로고    scopus 로고
    • A phase 1 trial of lenalidomide (REVLIMID®) with bortezomib (VELCADE®) in relapsed and refractory multiple myeloma
    • Richardson P, Schlossman R, Munshi N et al. A phase 1 trial of lenalidomide (REVLIMID®) with bortezomib (VELCADE®) in relapsed and refractory multiple myeloma. Blood 2005; 106: 110a
    • (2005) Blood , vol.106
    • Richardson, P.1    Schlossman, R.2    Munshi, N.3
  • 21
    • 33746340326 scopus 로고    scopus 로고
    • Velcade (V)-thalidomide (T)-dexamethasone (D) for advanced and refractory multiple myeloma (MM): Long-term follow-up of phase I-II trial UARK 2001-37: Superior outcome in patients with normal cytogenetics and no prior T
    • Zangari M, Barlogie B, Burns MJ et al. Velcade (V)-thalidomide (T)-dexamethasone (D) for advanced and refractory multiple myeloma (MM): long-term follow-up of phase I-II trial UARK 2001-37: superior outcome in patients with normal cytogenetics and no prior T. Blood 2005; 106: 717a
    • (2005) Blood , vol.106
    • Zangari, M.1    Barlogie, B.2    Burns, M.J.3
  • 22
    • 33745883858 scopus 로고    scopus 로고
    • Velcade™ plus melphalan, prednisone, and thalidomide (V-MPT) for advanced multiple myeloma
    • Palumbo A, Ambrosini MT, Pregno P et al. Velcade™ plus melphalan, prednisone, and thalidomide (V-MPT) for advanced multiple myeloma. Blood 2005; 106: 717a
    • (2005) Blood , vol.106
    • Palumbo, A.1    Ambrosini, M.T.2    Pregno, P.3
  • 23
    • 33746336016 scopus 로고    scopus 로고
    • Bortezomib in combination with high-dose dexamethasone and continuous low-dose oral cyclophosphamide for relapsed multiple myeloma
    • Kropff M, Bisping G, Liebisch P et al. Bortezomib in combination with high-dose dexamethasone and continuous low-dose oral cyclophosphamide for relapsed multiple myeloma. Blood 2005; 106: 716a
    • (2005) Blood , vol.106
    • Kropff, M.1    Bisping, G.2    Liebisch, P.3
  • 24
    • 20044376092 scopus 로고    scopus 로고
    • Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma
    • O'Connor OA, Wright J, Moskowitz C et al. Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J Clin Oncol 2005; 23: 676-684
    • (2005) J Clin Oncol , vol.23 , pp. 676-684
    • O'Connor, O.A.1    Wright, J.2    Moskowitz, C.3
  • 25
    • 20044396543 scopus 로고    scopus 로고
    • Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma
    • Goy A, Younes A, McLaughlin P et al. Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma. J Clin Oncol 2005; 23: 667-675
    • (2005) J Clin Oncol , vol.23 , pp. 667-675
    • Goy, A.1    Younes, A.2    McLaughlin, P.3
  • 26
    • 0038189917 scopus 로고    scopus 로고
    • Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib
    • Cusack JC. Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib. Cancer Treat Rev 2003; 29 (Suppl 1): 21-31
    • (2003) Cancer Treat Rev , vol.29 , Issue.SUPPL. 1 , pp. 21-31
    • Cusack, J.C.1
  • 27
    • 24944526723 scopus 로고    scopus 로고
    • Phase I trial of bortezomib and carboplatin in recurrent ovarian or primary peritoneal cancer
    • Aghajanian C, Dizon DS, Sabbatini P et al. Phase I trial of bortezomib and carboplatin in recurrent ovarian or primary peritoneal cancer. J Clin Oncol 2005; 23: 5943-5949
    • (2005) J Clin Oncol , vol.23 , pp. 5943-5949
    • Aghajanian, C.1    Dizon, D.S.2    Sabbatini, P.3
  • 28
    • 33646538009 scopus 로고    scopus 로고
    • Phase 1 Clinical Trial of KOS-953 + Bortezomib (BZ) in Relapsed Refractory Multiple Myeloma (MM)
    • Chanan-Khan AA, Richardson PG, Alsina M et al. Phase 1 Clinical Trial of KOS-953 + Bortezomib (BZ) in Relapsed Refractory Multiple Myeloma (MM). Blood 2005; 106: 109a
    • (2005) Blood , vol.106
    • Chanan-Khan, A.A.1    Richardson, P.G.2    Alsina, M.3
  • 29
    • 20844435806 scopus 로고    scopus 로고
    • Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma
    • Hideshima T, Bradner JE, Wong J et al. Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma. Proc Natl Acad Sci U S A 2005; 102: 8567-8572
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8567-8572
    • Hideshima, T.1    Bradner, J.E.2    Wong, J.3
  • 30
    • 27644562277 scopus 로고    scopus 로고
    • A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib
    • Chauhan D, Catley L, Li G et al. A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib. Cancer Cell 2005; 8: 407-419
    • (2005) Cancer Cell , vol.8 , pp. 407-419
    • Chauhan, D.1    Catley, L.2    Li, G.3
  • 31
    • 24744456734 scopus 로고    scopus 로고
    • Effects of PS-341 on the activity and composition of proteasomes in multiple myeloma cells
    • Altun M, Galardy PJ, Shringarpure R et al. Effects of PS-341 on the activity and composition of proteasomes in multiple myeloma cells. Cancer Res 2005; 65: 7896-7901
    • (2005) Cancer Res , vol.65 , pp. 7896-7901
    • Altun, M.1    Galardy, P.J.2    Shringarpure, R.3
  • 32
    • 0036682094 scopus 로고    scopus 로고
    • APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit
    • Wäsch R, Cross FR. APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit. Nature 2002; 418: 556-562
    • (2002) Nature , vol.418 , pp. 556-562
    • Wäsch, R.1    Cross, F.R.2
  • 33
    • 12444311754 scopus 로고    scopus 로고
    • Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells
    • Wäsch R, Engelbert D. Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells. Oncogene 2005; 24: 1-10
    • (2005) Oncogene , vol.24 , pp. 1-10
    • Wäsch, R.1    Engelbert, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.