Brain energy metabolism in experimental chronic diabetes: Effect of long-term administration of coenzyme Q10 and μ-3 polyunsaturated fatty acids

Biologia - Section Cellular and Molecular Biology

Volumn 60, Issue SUPPL. 17, 2005, Pages 105-108

  Sumbalová, Zuzana ^a   Kucharská, Jarmila ^a   Kašparová, Svatava ^b   Mlynárik, Vladimír ^c   Bystrický, Peter ^c   Božek, Peter ^d   Uličná, Ol'ga ^a   Vančová, Ol'ga ^a   Singh, Ram B ^e   Gvozdjáková, Anna ^a  

^a Bratislava   (Slovakia)

^b SLOVAK UNIVERSITY OF TECHNOLOGY   (Slovakia)

^c Derer 's University Hospital Slovakia   (Slovakia)

^d State Hospital   (Slovakia)

^e Medical Hospital and Research Centre Moradabad   (India)

Author keywords

Ageing; Creatine kinase; Mitochondria; MRS; Oxidative phosphorylation; Rats; Saturation transfer

Indexed keywords

RATTUS NORVEGICUS;

EID: 33751321598     PISSN: 13356399     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (32)

1. ASWATHY, R.N., MANGATT, P.B. & CHERAMADATHIKUDYIL, S.P. 1998. Effect of pyridoxine and insulin administration on brain glutamate dehydrogenase activity and blood glucose control in streptozotocin-induced diabetic rats. Biochim. Biophys. Acta 1381: 351-354.
2. BERGER, J. & MOLLER, D. E. 2002. The mechanisms of action of PPARs. Annu. Rev. Med. 53: 409-435.
3. BIESSELS, G.J., VAN DER HEIDE, L.P., KAMAL, A., BLEYS, R.L. & GIPSEN, E.H. 2002. Aging and diabetes: implications for brain function. Eur. J. Pharmacol. 441: 1-14.
4. CRANE, F.L. & NAVAS, P. 1997. The diversity of coenzyme Q function. Molec. Aspects Med. 18 (Suppl.): 1-6.
5. GVOZDJÁKOVÁ, A., KUCHARSKÁ, J., BRAUNOVÁ, Z. & KOLESÁR, P. 1997. Effects of Dia-Lecia on the antioxidative status and basic parameters of metabolism of fats and sugars in diabetic patients. Slov. Lekár 12: 35-39.
6. HONG, J., KIM, M., PARK, M., KWANG, O., LEE, I., BYUN, B. H., LEE, S., LEE, K. & RHEE, S. 2004. Effects of vitamin E on oxidative stress and membrane fluidity in brain of streptozotocin-induced diabetic rats. Clin. Chim. Acta 340: 107-115.
7. JOST, C.R., VAN DER ZEE, C.E.E. M., ZANDT, H.J.A., OERLEAMANS, F., VERHEIJ, M., STREIJGER, F., FRANSEN, J., HEERSCHAP, A., COOLS, A.R., WIERINGA, B. 2002. Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility. Eur. J. Neurosci. 15: 1692-1706.
8. KAUR, G. & BHARDWAJ, S.K. 1998. The impact of diabetes on CNS. Role of bioenergetic defects. Mol. Chem. Neuropathol. 35: 119-131.
9. LANG, J.K., GOHIL, K. & PACKER, L. 1986. Simultaneous determination of tocopherols, ubiquinols, and ubiquinones in blood, plasma, tissue homogenates, and subcellular fractions. Anal. Biochem. 157: 106-116.
10. LAPIDOT, A. & HABER, S. 2001. Effect of endogenous β-hydroxybutyrate on glucose metabolism in the diabetic rabbit brain: A 13C-magnetic resonance spectroscopy study of U-13C glucose metabolites. J. Neurosci Res. 64: 207-216.
11. LAWEN, A., MARTINUS, R.D., MCMULLEN, G.L., NAGLEY, P., VAILLANT, F., WOLVETANG, E.J. & LINNANE, A.W. 1994. The universality of bioenergetic disease: the role of mitochondrial mutation and the putative inter-relationship between mitochondria and plasma membrane NADH oxidoreductase. Mol. Aspects Med. 15: S13-S27.
12. LEAF, A. 2001. The electrophysiologic basis for the antiarrhythmic and anticonvulsant effects of n-3 polyunsaturated fatty acids: heart and brain. Lipids 36 (Suppl.): S107-S110.
13. LEONG, S.F. & LOUNG, T.K. 1991. Diabetes induced by streptozotocin causes reduced Na-K ATPase in the brain. Neurochem. Res. 16: 1161-1165.
14. LOWRY, D.H., ROSENBROUGH, N.Y., FARR, A.L. & RANDALL, R.J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-276.
15. MATSUMOTO, Y., KANEKO, M., KOBAYASHI, A., FUJISE, Y. & YAMAZAKI, N. 1995. Creatine kinase kinetics in diabetic cardiomyopathy. Am. J. Physiol. 268: E1070-E1076.
16. MLYNÁRIK, V., KAŠPAROVÁ, S., LIPTAJ, T., DOBROTA, D., HORECKÝ, J. & BELAN, V. 1998. Creatine kinase reaction rates in brain during chronic ischemia. MAGMA 7: 162-165.
17. MOREIRA, P.I., SANTOS, M.S., MORENO, A.M., PROENCA, T., SEICA, R. & OLIVEIRA, C.R. 2004. Effect of streptozotocin-induced diabetes on rat brain mitochondria. J. Neuroendocrinol. 16: 32-38.
18. MORRÉ, D.J. 2005. Quinone oxidoreductases of the plasma membrane. Methods Enzymol. 378: 179-199.
19. OVIDE-BORDEAUX, S. & GRYNBERG, A. 2004. Docosahexacnoic acid affects insulin deficiency- and insulin resistance-induced alterations in cardiac mitochondria. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286: R519-527.
20. 2+ activation of PDH. Am. J. Physiol. 276: H149-H158.
21. st Conference of the International Coenzyme Q10 Association, Boston, MA, USA, May 1998; 118.
22. SALCEDA, R., VILCHIS, C., COFFE, V. & HERNANDEZ-MUNOZ, R. 1998. Changes in the redox state in the retina and brain during the onset of diabetes in rats. Neurochem. Res. 23: 893-897.
23. SARMA, J.S., IKEDA, S., FISCHER, R., MARUYAMA, Y., WEISHAAR, R. & BING, R.J. 1976. Biochemical and contractile properties of heart muscle after prolonged alcohol administration. J. Mol. Cell. Cardiol. 8: 951-972.
24. SIMPSON, I.A., APPEL, N.M., HOKARI, M., OKI, J., HOLMAN, G.D., MAHER, F., KOEHLER-STEC, E.M., VANNUCCI, S. & SMITH, Q.R. 1999. Blood-brain barrier glucose transporter: effects of hypo- and hyperglycemia revisited. J. Neurochem. 72: 238-247.
25. 31P NMR magnetization transfer study of the intact beating rat heart. J. Mol. Cell. Cardiol. 31: 2175-2189.
26. SURESH, Y. & DAS, U.N. 2003. Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus: effect of ω-3 fatty acids. Nutrition 19: 213-228.
27. 2+ homeostasis in primary sensory neurons of diabetic mice. Neuroreport 9: 1121-1125.
28. VILLALBA, J.M., NAVARRO, F., CORDOBA, F., SERRANO, A., ARROYO, A., CRANE, F.L. & NAVAS, P. 1995. Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport. Proc. Natl. Acad. Sci. USA 92: 4887-4891.
29. WALLIMANN, T., DOLER, M., SCHLATTNER, U., EDER, M., HORNEMANN, T., KRAFT, T. & STOLTZ, M. 1998. Creatine kinase: An enzyme with central role in cellular energy metabolism. MAGMA 6: 116-119.
30. ZIEGELHOFFER, A., WACZULÍKOVÁ, I., RAVINGEROVÁ, T., ZIEGELHOFFER-MIHALOVIČOVÁ, B., NECKÁŘ, J. & STYK, J. 2003. Augmented energy transfer in rat heart mitochondria: compensatory response to abnormal household of energy in acute diabetes, pp. 439-454. In: PIERCE, G.N., NAGANO, M., ZAHRADKA, P. & DHALLA, N.S. (eds), Atherosclerosis, Hypertension and Diabetes, Kluwer Academic Publishers, Boston.
31. ZIEGELHOFFER-MIHALOVIČOVÁ, B., OKRUHLICOVÁ, L., TRIBULOVÁ, N., RAVINGEROVÁ, T., VOLKOVOVA, K., SEBOKOVÁ, J. & ZIEGEL-HOFFER, A. 1997. Mitochondrial contact sites detected by creatine phosphokinase activity in the hearts of normal and diabetic rats: is mitochondrial contact sites formation a calcium-dependent process? Gen. Physiol. Biophys. 16: 329-338.
32. ZHAO, X., BASSIRAT, M., ZEINAB, K. & HELME, R.D. 1999. Effects of diabetes on creatine kinase activity in streptozotoc-in-diabetic rats. Chin. Med. J. 112: 1028-31.