-
3
-
-
0000520727
-
Virus interference I. The interferon
-
Isaacs A, Lindenmann J (1957) Virus interference I. The interferon. Proc R Soc Lond 147:258-267
-
(1957)
Proc R Soc Lond
, vol.147
, pp. 258-267
-
-
Isaacs, A.1
Lindenmann, J.2
-
4
-
-
0028362516
-
The interferons: A biological system with therapeutic potential in viral infections
-
Baron S, Dianzani F (1994) The interferons: a biological system with therapeutic potential in viral infections. Antiviral Res 24:97-110
-
(1994)
Antiviral Res
, vol.24
, pp. 97-110
-
-
Baron, S.1
Dianzani, F.2
-
5
-
-
0028051363
-
Role of interferons in the regulation of cell proliferation, differentiation and development
-
Hertzog PJ, Hwang SY, Kola I (1994) Role of interferons in the regulation of cell proliferation, differentiation and development. Mol Reprod Dev 39:226-232
-
(1994)
Mol Reprod Dev
, vol.39
, pp. 226-232
-
-
Hertzog, P.J.1
Hwang, S.Y.2
Kola, I.3
-
6
-
-
0028117299
-
Cytokine therapeutics: Lessons from interferon-α
-
Gutterman JU (1994) Cytokine therapeutics: lessons from interferon-α. Proc Natl Acad Sci USA 91:1198-1205
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1198-1205
-
-
Gutterman, J.U.1
-
7
-
-
0023893294
-
Interferons in malignancy: Biological products or biological response modifiers?
-
(Bethesda)
-
Krown SE (1988) Interferons in malignancy: biological products or biological response modifiers? J Natl Cancer Inst (Bethesda) 80:306-309
-
(1988)
J Natl Cancer Inst
, vol.80
, pp. 306-309
-
-
Krown, S.E.1
-
8
-
-
0027934194
-
Organ-site dependent expression of bFGF in human renal cell carcinoma cells
-
Singh RK, Bucana CD, Gutman M, Fan D, Wilson MR, Fidler IJ (1994) Organ-site dependent expression of bFGF in human renal cell carcinoma cells. Am J Pathol 145:365-374
-
(1994)
Am J Pathol
, vol.145
, pp. 365-374
-
-
Singh, R.K.1
Bucana, C.D.2
Gutman, M.3
Fan, D.4
Wilson, M.R.5
Fidler, I.J.6
-
9
-
-
0026756731
-
Downregulation of interleukin-8 gene expression in human fibroblasts: Unique mechanism of transcriptional inhibition of interferon
-
Oliveira IC, Sciavolino PJ, Lee TH, Vilcek J (1992) Downregulation of interleukin-8 gene expression in human fibroblasts: unique mechanism of transcriptional inhibition of interferon. Proc Natl Acad Sci USA 89:9049-9053
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9049-9053
-
-
Oliveira, I.C.1
Sciavolino, P.J.2
Lee, T.H.3
Vilcek, J.4
-
10
-
-
0027411513
-
Modulation of the invasive phenotype of human colon carcinoma cells by fibroblasts from orthotopic or ectopic organs of nude mice
-
Fabra A, Nakajima M, Bucana CD, Fidler IJ (1992) Modulation of the invasive phenotype of human colon carcinoma cells by fibroblasts from orthotopic or ectopic organs of nude mice. Differentiation 52:101-110
-
(1992)
Differentiation
, vol.52
, pp. 101-110
-
-
Fabra, A.1
Nakajima, M.2
Bucana, C.D.3
Fidler, I.J.4
-
11
-
-
0023805049
-
Phase II trial of a combination of interferon-β ser and interferon-γ in patients with advanced malignant melanoma
-
Schiller JH, Storer B, Bittner G, Willson JK, Borden EC (1988) Phase II trial of a combination of interferon-β ser and interferon-γ in patients with advanced malignant melanoma. J Interferon Res 8:581-589
-
(1988)
J Interferon Res
, vol.8
, pp. 581-589
-
-
Schiller, J.H.1
Storer, B.2
Bittner, G.3
Willson, J.K.4
Borden, E.C.5
-
12
-
-
9344248389
-
Antitumor activity of 1 M-tegaful- 0.4 M 5-chloro-2, 4-dihydroxypyridine- 1M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats
-
Shirasaka T, Nakano K, Fukushima M, Takechi T, Satake H, Uchida J, Fujioka A, Saito H, Okabe H, Oyama K, Takeda S, Unemi N, Fukushima M (1996) Antitumor activity of 1 M-tegaful- 0.4 M 5-chloro-2, 4-dihydroxypyridine-1M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats. Cancer Res 56:2602-2606
-
(1996)
Cancer Res
, vol.56
, pp. 2602-2606
-
-
Shirasaka, T.1
Nakano, K.2
Fukushima, M.3
Takechi, T.4
Satake, H.5
Uchida, J.6
Fujioka, A.7
Saito, H.8
Okabe, H.9
Oyama, K.10
Takeda, S.11
Unemi, N.12
Fukushima, M.13
-
13
-
-
0018869414
-
Activation of Ftorafur [R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil] to 5-fluorouracil and gamma-butyrolactone
-
Au JL, Sadee W (1980) Activation of Ftorafur [R,S-1-(tetrahydro-2- furanyl)-5-fluorouracil] to 5-fluorouracil and gamma-butyrolactone. Cancer Res 40:2814-2819
-
(1980)
Cancer Res
, vol.40
, pp. 2814-2819
-
-
Au, J.L.1
Sadee, W.2
-
14
-
-
0023250474
-
Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extracts
-
Tatsumi K, Fukushima M, Shirasaka T, Fujii S (1987) Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extracts. Jpn J Cancer Res 78:748-755
-
(1987)
Jpn J Cancer Res
, vol.78
, pp. 748-755
-
-
Tatsumi, K.1
Fukushima, M.2
Shirasaka, T.3
Fujii, S.4
-
15
-
-
0027227591
-
Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats
-
Shirasaka T, Shimamoto Y, Fukushima M (1993) Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res 53:4004-4009
-
(1993)
Cancer Res
, vol.53
, pp. 4004-4009
-
-
Shirasaka, T.1
Shimamoto, Y.2
Fukushima, M.3
-
16
-
-
0032189218
-
Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients
-
Sakata Y, Ohtsu A, Horikoshi N, Sugimachi K, Mitachi Y, Taguchi T (1998) Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients. Eur J Cancer 34:1715-1720
-
(1998)
Eur J Cancer
, vol.34
, pp. 1715-1720
-
-
Sakata, Y.1
Ohtsu, A.2
Horikoshi, N.3
Sugimachi, K.4
Mitachi, Y.5
Taguchi, T.6
-
17
-
-
0034089123
-
Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma
-
Ohtsu A, Baba H, Sakata Y, Mitachi Y, Horikoshi N, Sugimachi K, Taguchi T (2000) Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma. Br J Cancer 83:141-145
-
(2000)
Br J Cancer
, vol.83
, pp. 141-145
-
-
Ohtsu, A.1
Baba, H.2
Sakata, Y.3
Mitachi, Y.4
Horikoshi, N.5
Sugimachi, K.6
Taguchi, T.7
-
18
-
-
0036835318
-
High response rates in patients with pancreatic cancer using the novel oral fluoropyrimidine S-1
-
Hayashi K, Imaizumi T, Uchida K, Kuromachi H, Takasaki K (2002) High response rates in patients with pancreatic cancer using the novel oral fluoropyrimidine S-1. Oncol Rep 9:1355-1361
-
(2002)
Oncol Rep
, vol.9
, pp. 1355-1361
-
-
Hayashi, K.1
Imaizumi, T.2
Uchida, K.3
Kuromachi, H.4
Takasaki, K.5
-
19
-
-
1642621731
-
Preclinical and clinical studies of 5-fluorouracil (FURA) and recombinant α-2a-interferon (IFN) against gastrointestinal (GI) malignancies
-
Wadler S, Schwartz EL, Goldman M, Lyver A, Itri L, Wiernik PH (1988) Preclinical and clinical studies of 5-fluorouracil (FURA) and recombinant α-2a-interferon (IFN) against gastrointestinal (GI) malignancies. Clin Res 36:803A
-
(1988)
Clin Res
, vol.36
-
-
Wadler, S.1
Schwartz, E.L.2
Goldman, M.3
Lyver, A.4
Itri, L.5
Wiernik, P.H.6
-
20
-
-
0037080269
-
Combined intraarterial 5-fluorouracil and subcutaneous interferon-α therapy for advanced hepatocellular carcinoma with tumor thrombi in the major portal branches
-
Sakon M, Nagano H, Dono K, et al (2002) Combined intraarterial 5-fluorouracil and subcutaneous interferon-α therapy for advanced hepatocellular carcinoma with tumor thrombi in the major portal branches. Cancer 94:435-442
-
(2002)
Cancer
, vol.94
, pp. 435-442
-
-
Sakon, M.1
Nagano, H.2
Dono, K.3
-
21
-
-
0026600296
-
Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cells
-
Schwartz EL, Hoffman M, O'Connor CJ, Wadler S (1992) Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cells. Biochem Biophys Res Commun 182:1232-1239
-
(1992)
Biochem Biophys Res Commun
, vol.182
, pp. 1232-1239
-
-
Schwartz, E.L.1
Hoffman, M.2
O'Connor, C.J.3
Wadler, S.4
-
22
-
-
0024414582
-
Interferon effects upon fluorouracil metabolism by HL-60 cells
-
Elias L, Sandoval JM (1989) Interferon effects upon fluorouracil metabolism by HL-60 cells. Biochem Biophys Res Commun 163:867-874
-
(1989)
Biochem Biophys Res Commun
, vol.163
, pp. 867-874
-
-
Elias, L.1
Sandoval, J.M.2
-
23
-
-
0033941539
-
Augmentation of antitumor activity of 5-fluorouracil by interferon-α is associated with up-regulation of p27Kip1 in human hepatocellular carcinoma cells
-
Eguchi H, Nagano H, Yamamoto H et al (2000) Augmentation of antitumor activity of 5-fluorouracil by interferon-α is associated with up-regulation of p27Kip1 in human hepatocellular carcinoma cells. Clin Cancer Res 6:2881-2890
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2881-2890
-
-
Eguchi, H.1
Nagano, H.2
Yamamoto, H.3
-
24
-
-
0033107768
-
In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice
-
Bruns CJ, Harbison MT, Kuniyasu H, Eue I, Fidler IJ (1999) In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice. Neoplasia 1:50-62
-
(1999)
Neoplasia
, vol.1
, pp. 50-62
-
-
Bruns, C.J.1
Harbison, M.T.2
Kuniyasu, H.3
Eue, I.4
Fidler, I.J.5
-
25
-
-
0002494823
-
A water-soluble tetrazolium salt useful for colorimetric cell viability assay
-
Tominaga H, Ishiyama M, Ohseto F (1999) A water-soluble tetrazolium salt useful for colorimetric cell viability assay. Anal Commun 36:47
-
(1999)
Anal Commun
, vol.36
, pp. 47
-
-
Tominaga, H.1
Ishiyama, M.2
Ohseto, F.3
-
26
-
-
0035477366
-
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models
-
Wen Y, Yan DH, Wang B, Spohn B, Ding Y, Shao R, Zou Y, Xie K, Hung MC (2001) p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models. Cancer Res 61:7142-7147
-
(2001)
Cancer Res
, vol.61
, pp. 7142-7147
-
-
Wen, Y.1
Yan, D.H.2
Wang, B.3
Spohn, B.4
Ding, Y.5
Shao, R.6
Zou, Y.7
Xie, K.8
Hung, M.C.9
-
27
-
-
0028212294
-
Monoclonal antibodies specific for endothelial cells of mouse blood vessels: Their application in the identification of adult and embryonic endothelium
-
Vecchi A, Garlanda C, Lampugnani MG, Resnati M, Matteucci C, Stoppacciaro A, Schnurch H, Risau W, Ruco L, Mantovani A (1994) Monoclonal antibodies specific for endothelial cells of mouse blood vessels: their application in the identification of adult and embryonic endothelium. Eur J Cell Biol 63:247-254
-
(1994)
Eur J Cell Biol
, vol.63
, pp. 247-254
-
-
Vecchi, A.1
Garlanda, C.2
Lampugnani, M.G.3
Resnati, M.4
Matteucci, C.5
Stoppacciaro, A.6
Schnurch, H.7
Risau, W.8
Ruco, L.9
Mantovani, A.10
-
28
-
-
0026083903
-
Tumor angiogenesis and metastasis: Correlation in invasive breast carcinoma
-
Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med 324:1-8
-
(1991)
N Engl J Med
, vol.324
, pp. 1-8
-
-
Weidner, N.1
Semple, J.P.2
Welch, W.R.3
Folkman, J.4
-
29
-
-
0020056302
-
In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas
-
Spears CP, Shahinian AH, Moran RG, Heidelberger C, Corbett TH (1982) In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas. Cancer Res 42:450-456
-
(1982)
Cancer Res
, vol.42
, pp. 450-456
-
-
Spears, C.P.1
Shahinian, A.H.2
Moran, R.G.3
Heidelberger, C.4
Corbett, T.H.5
-
30
-
-
0036248955
-
Roles of thymidylate synthase and dihydropyrimidine dehydrogenase on tumour progression and sensitivity to 5-fluorouracil in human gastric cancer
-
Terashima M, Irinoda T, Fujiwara H (2002) Roles of thymidylate synthase and dihydropyrimidine dehydrogenase on tumour progression and sensitivity to 5-fluorouracil in human gastric cancer. Anticancer Res 22:761-768
-
(2002)
Anticancer Res
, vol.22
, pp. 761-768
-
-
Terashima, M.1
Irinoda, T.2
Fujiwara, H.3
-
31
-
-
0030879693
-
Pharmacokinetic analysis of free radicals by in vivo BCM (blood circulation monitoring)-ESR method
-
Takechi K, Tamura H, Yamaoka K, Sakurai H (1997) Pharmacokinetic analysis of free radicals by in vivo BCM (blood circulation monitoring)-ESR method. Free Radic Res 26:483-496
-
(1997)
Free Radic Res
, vol.26
, pp. 483-496
-
-
Takechi, K.1
Tamura, H.2
Yamaoka, K.3
Sakurai, H.4
-
32
-
-
0036289092
-
Combination chemotherapy for advanced hepatocellular carcinoma complicated by major portal vein thrombosis
-
Kaneko S, Urabe T, Kobayashi K (2002) Combination chemotherapy for advanced hepatocellular carcinoma complicated by major portal vein thrombosis. Oncology 62:69-73
-
(2002)
Oncology
, vol.62
, pp. 69-73
-
-
Kaneko, S.1
Urabe, T.2
Kobayashi, K.3
-
33
-
-
0037406666
-
Interferon-based adjuvant chemoradiation therapy after pancreatico-duodenectomy for pancreatic adenocarcinoma
-
Picozzi VJ, Kozarek RA, Traverso LW (2003) Interferon-based adjuvant chemoradiation therapy after pancreatico-duodenectomy for pancreatic adenocarcinoma. Am J Surg 185:4767-4780
-
(2003)
Am J Surg
, vol.185
, pp. 4767-4780
-
-
Picozzi, V.J.1
Kozarek, R.A.2
Traverso, L.W.3
-
34
-
-
0026600296
-
Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cells
-
Schwartz EL, Hoffman M, O'Connor CJ, Wadler S (1992) Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cells. Biochem Biophys Res Commun 182:1232-1239
-
(1992)
Biochem Biophys Res Commun
, vol.182
, pp. 1232-1239
-
-
Schwartz, E.L.1
Hoffman, M.2
O'Connor, C.J.3
Wadler, S.4
-
35
-
-
0024414582
-
Interferon effects upon fluorouracil metabolism by HL-60 cells
-
Elias L, Sandoval JM (1989) Interferon effects upon fluorouracil metabolism by HL-60 cells. Biochem Biophys Res Commun 163:867-874
-
(1989)
Biochem Biophys Res Commun
, vol.163
, pp. 867-874
-
-
Elias, L.1
Sandoval, J.M.2
-
36
-
-
0029835349
-
Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators
-
Shirasaka T, Shimamato Y, Ohshimo H, Yamaguchi M, Kato T, Yonekura K, Fukushima M (1996) Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs 7:548-557
-
(1996)
Anticancer Drugs
, vol.7
, pp. 548-557
-
-
Shirasaka, T.1
Shimamato, Y.2
Ohshimo, H.3
Yamaguchi, M.4
Kato, T.5
Yonekura, K.6
Fukushima, M.7
-
37
-
-
11544323426
-
Preclinical antitumor efficacy of S-1: A new oral formulation of 5-fluorouracil on human tumor xenografts
-
Fukushima M, Satake H, Uchida J, Shimamoto Y, Kato T, Okabe H (1998) Preclinical antitumor efficacy of S-1: a new oral formulation of 5-fluorouracil on human tumor xenografts. Int J Oncol 13:693-698
-
(1998)
Int J Oncol
, vol.13
, pp. 693-698
-
-
Fukushima, M.1
Satake, H.2
Uchida, J.3
Shimamoto, Y.4
Kato, T.5
Okabe, H.6
-
38
-
-
0028114985
-
The implications of angiogenesis for the biology and therapy of cancer metastasis
-
Fidler IJ, Ellis LM (1994) The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 79:185-188
-
(1994)
Cell
, vol.79
, pp. 185-188
-
-
Fidler, I.J.1
Ellis, L.M.2
-
39
-
-
0036207102
-
Results of a randomised phase II study of cisplatin plus 5-fluorouracil versus cisplatin plus 5-fluorouracil with alpha-interferon in metastatic pancreatic cancer: An EORTC gastrointestinal tract cancer group trial
-
Wagener DJ, Wils JA, Kok TC, Planting A, Couvreur ML, Baron B (2002) Results of a randomised phase II study of cisplatin plus 5-fluorouracil versus cisplatin plus 5-fluorouracil with alpha-interferon in metastatic pancreatic cancer: an EORTC gastrointestinal tract cancer group trial. Eur J Cancer 38:648-653
-
(2002)
Eur J Cancer
, vol.38
, pp. 648-653
-
-
Wagener, D.J.1
Wils, J.A.2
Kok, T.C.3
Planting, A.4
Couvreur, M.L.5
Baron, B.6
-
40
-
-
0036206774
-
Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma
-
Furudoi A, Tanaka S, Haruma K, Kitadai Y, Yoshihara M, Chayama K, Shimamoto F (2002) Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma. Oncology 62:157-166
-
(2002)
Oncology
, vol.62
, pp. 157-166
-
-
Furudoi, A.1
Tanaka, S.2
Haruma, K.3
Kitadai, Y.4
Yoshihara, M.5
Chayama, K.6
Shimamoto, F.7
|