메뉴 건너뛰기




Volumn 14, Issue 4, 2006, Pages 413-421

Aripiprazole as a potential pharmacotherapy for stimulant dependence: Human laboratory studies with d-amphetamine

Author keywords

Amphetamine; Aripiprazole; Cocaine; Human; Pharmacotherapy; Stimulant dependence

Indexed keywords

ARIPIPRAZOLE; DEXAMPHETAMINE; DOPAMINE 2 RECEPTOR; NEUROLEPTIC AGENT;

EID: 33751254731     PISSN: 10641297     EISSN: None     Source Type: Journal    
DOI: 10.1037/1064-1297.14.4.413     Document Type: Article
Times cited : (34)

References (63)
  • 2
    • 0023694682 scopus 로고
    • The relationship of stimulus control to the treatment of substance abuse
    • B. A. Ray (Ed.), Rockville, MD: U.S. Department of Health and Human Services
    • Bickel, W. K., & Kelly, T. H. (1988). The relationship of stimulus control to the treatment of substance abuse. In B. A. Ray (Ed.), Learning factors in substance abuse (pp. 122-140). Rockville, MD: U.S. Department of Health and Human Services.
    • (1988) Learning Factors in Substance Abuse , pp. 122-140
    • Bickel, W.K.1    Kelly, T.H.2
  • 3
    • 0028879206 scopus 로고
    • Role of dopamine in d-amphetamine-induced euphoria in normal, healthy volunteers
    • Brauer, L. H., & de Wit, H. (1995). Role of dopamine in d-amphetamine-induced euphoria in normal, healthy volunteers. Experimental and Clinical Psychopharmacology, 3, 371-381.
    • (1995) Experimental and Clinical Psychopharmacology , vol.3 , pp. 371-381
    • Brauer, L.H.1    De Wit, H.2
  • 4
    • 0030027098 scopus 로고    scopus 로고
    • Subjective responses to d-amphetamine alone and after pimozide pretreatment in normal, healthy volunteers
    • Brauer, L. H., & de Wit, H. (1996). Subjective responses to d-amphetamine alone and after pimozide pretreatment in normal, healthy volunteers. Biological Psychiatry, 39, 26-32.
    • (1996) Biological Psychiatry , vol.39 , pp. 26-32
    • Brauer, L.H.1    De Wit, H.2
  • 5
    • 0031055996 scopus 로고    scopus 로고
    • High dose pimozide does not block amphetamine-induced euphoria in normal volunteers
    • Brauer, L. H., & de Wit, H. (1997). High dose pimozide does not block amphetamine-induced euphoria in normal volunteers. Pharmacology Biochemistry and Behavior, 56, 265-272.
    • (1997) Pharmacology Biochemistry and Behavior , vol.56 , pp. 265-272
    • Brauer, L.H.1    De Wit, H.2
  • 6
    • 0031027754 scopus 로고    scopus 로고
    • Dopamine ligands and the stimulus effects of amphetamine: Animal models versus human laboratory data
    • Brauer, L. H., Goudie, A. J., & de Wit, H. (1997). Dopamine ligands and the stimulus effects of amphetamine: Animal models versus human laboratory data. Psychopharmacology, 130, 2-13.
    • (1997) Psychopharmacology , vol.130 , pp. 2-13
    • Brauer, L.H.1    Goudie, A.J.2    De Wit, H.3
  • 8
    • 21744459699 scopus 로고    scopus 로고
    • Switching outpatients with bipolar or schizoaffective disorders and substance abuse from their current antipsychotic to aripiprazole
    • Brown, E. S., Jeffress, J., Liggin, J. D., Garza, M., & Beard, L. (2005). Switching outpatients with bipolar or schizoaffective disorders and substance abuse from their current antipsychotic to aripiprazole. Journal of Clinical Psychiatry, 66, 756-760.
    • (2005) Journal of Clinical Psychiatry , vol.66 , pp. 756-760
    • Brown, E.S.1    Jeffress, J.2    Liggin, J.D.3    Garza, M.4    Beard, L.5
  • 11
    • 0033970304 scopus 로고    scopus 로고
    • Dopamine receptor partial agonists could address the duality of cocaine craving
    • Childress, A. R., & O'Brien, C. P. (2000). Dopamine receptor partial agonists could address the duality of cocaine craving. Trends in Pharmacological Science, 21, 6-9.
    • (2000) Trends in Pharmacological Science , vol.21 , pp. 6-9
    • Childress, A.R.1    O'Brien, C.P.2
  • 12
    • 0019780124 scopus 로고
    • Reinstatement of cocaine-reinforced responding in the rat
    • de Wit, H., & Stewart, J. (1981). Reinstatement of cocaine-reinforced responding in the rat. Psychopharmacology, 75, 134-143.
    • (1981) Psychopharmacology , vol.75 , pp. 134-143
    • De Wit, H.1    Stewart, J.2
  • 14
    • 33751252050 scopus 로고    scopus 로고
    • Drug Abuse Warning Network. Retrieved September 20, 2006, from
    • Drug Abuse Warning Network. (2004). Major drugs of abuse in ED visits, 2002 Update. Retrieved September 20, 2006, from http://dawninfo.samhsa.gov/ old_dawn/pubs_94_02/shortreports/
    • (2004) Major Drugs of Abuse in ED Visits, 2002 Update
  • 15
    • 33751236570 scopus 로고    scopus 로고
    • Drug and Alcohol Services Information System. Retrieved April 3, 2006, from
    • Drug and Alcohol Services Information System. (2006). Trends in methamphetamine/amphetamine admissions to treatment, 1993-2003. Retrieved April 3, 2006, from http://oas.samhsa .gov/2k6/methTx/methTX.cfm
    • (2006) Trends in Methamphetamine/amphetamine Admissions to Treatment, 1993-2003
  • 16
    • 0027077719 scopus 로고
    • 2 dopamine receptor agonists in rats discriminating d-amphetamine from saline
    • 2 dopamine receptor agonists in rats discriminating d-amphetamine from saline. Behavioural Pharmacology, 3, 609-619.
    • (1992) Behavioural Pharmacology , vol.3 , pp. 609-619
    • Exner, M.1    Clark, D.2
  • 17
    • 0025825517 scopus 로고
    • Assessment of abuse liability of stimulant drugs in humans: A methodological survey
    • Foltin, R. W., & Fischman, M. W. (1991). Assessment of abuse liability of stimulant drugs in humans: A methodological survey. Drug and Alcohol Dependence, 28, 3-48.
    • (1991) Drug and Alcohol Dependence , vol.28 , pp. 3-48
    • Foltin, R.W.1    Fischman, M.W.2
  • 19
    • 4444324187 scopus 로고    scopus 로고
    • Agonist-like, replacement pharmacotherapy for stimulant abuse and dependence
    • Grabowski, J., Shearer, J., Merrill, J., & Negus, S. S. (2004). Agonist-like, replacement pharmacotherapy for stimulant abuse and dependence. Addictive Behavior, 29, 1439-1464.
    • (2004) Addictive Behavior , vol.29 , pp. 1439-1464
    • Grabowski, J.1    Shearer, J.2    Merrill, J.3    Negus, S.S.4
  • 20
    • 0037986601 scopus 로고    scopus 로고
    • Principles of initial experimental drug abuse liability assessment in humans
    • Griffiths, R. R., Bigelow, G. E., & Ator, N. A. (2003). Principles of initial experimental drug abuse liability assessment in humans. Drug and Alcohol Dependence, 70, S41-S54.
    • (2003) Drug and Alcohol Dependence , vol.70
    • Griffiths, R.R.1    Bigelow, G.E.2    Ator, N.A.3
  • 22
    • 0036449515 scopus 로고    scopus 로고
    • Effects of the NMDA antagonist memantine on human methamphetamine discrimination
    • Hart, C. L., Haney, M., Foltin, R. W., & Fischman, M. W. (2002). Effects of the NMDA antagonist memantine on human methamphetamine discrimination. Psychopharmacology, 164, 376-384.
    • (2002) Psychopharmacology , vol.164 , pp. 376-384
    • Hart, C.L.1    Haney, M.2    Foltin, R.W.3    Fischman, M.W.4
  • 23
    • 0000495137 scopus 로고    scopus 로고
    • Catecholamines and sympathomimetic drugs, and adrenergic receptor antagonists
    • J. G. Hardman & L. E. Limbird (Eds.) & A. G. Gilman (Consulting Ed.), New York: McGraw-Hill
    • Hoffman, B. B. (2001). Catecholamines and sympathomimetic drugs, and adrenergic receptor antagonists. In J. G. Hardman & L. E. Limbird (Eds.) & A. G. Gilman (Consulting Ed.), Goodman & Gilman's The pharmacological basis of therapeutics (pp. 215-268). New York: McGraw-Hill.
    • (2001) Goodman & Gilman's the Pharmacological Basis of Therapeutics , pp. 215-268
    • Hoffman, B.B.1
  • 24
    • 0035011237 scopus 로고    scopus 로고
    • A dopamine partial agonist and antagonist block amphetamine self-administration in a progressive-ratio schedule
    • Izzo, E., Orsini, C., Koob, G., & Pulvirenti, L. (2001). A dopamine partial agonist and antagonist block amphetamine self-administration in a progressive-ratio schedule. Pharmacology Biochemistry and Behavior, 68, 701-708.
    • (2001) Pharmacology Biochemistry and Behavior , vol.68 , pp. 701-708
    • Izzo, E.1    Orsini, C.2    Koob, G.3    Pulvirenti, L.4
  • 25
    • 0022587414 scopus 로고
    • Dextroamphetamine-induced arousal in human subjects as a model for mania
    • Jacobs, D., & Silverstone, T. (1986). Dextroamphetamine-induced arousal in human subjects as a model for mania. Psychological Medicine, 16, 323-329.
    • (1986) Psychological Medicine , vol.16 , pp. 323-329
    • Jacobs, D.1    Silverstone, T.2
  • 26
    • 0000369784 scopus 로고
    • Assessment of the abuse potentiality of morphine like drugs (methods used in man)
    • W. R. Martin (Ed.), New York: Springer-Verlag
    • Jasinski, D. (1977). Assessment of the abuse potentiality of morphine like drugs (methods used in man). In W. R. Martin (Ed.), Drug addiction I (pp. 197-258). New York: Springer-Verlag.
    • (1977) Drug Addiction I , pp. 197-258
    • Jasinski, D.1
  • 27
    • 33645105861 scopus 로고    scopus 로고
    • Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers
    • Johanson, C. E., Frey, K. A., Lundahl, L. H., Keenan, P., Lockhart, N., Roll, J., et al. (2006). Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers. Psychopharmacology, 185, 327-338.
    • (2006) Psychopharmacology , vol.185 , pp. 327-338
    • Johanson, C.E.1    Frey, K.A.2    Lundahl, L.H.3    Keenan, P.4    Lockhart, N.5    Roll, J.6
  • 29
    • 15044363948 scopus 로고    scopus 로고
    • Effects of isradipine on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition
    • Johnson, B. A., Roache, J. D., Ait-Daoud, N., Wallace, C., Wells, L. T., & Wang, Y. (2005). Effects of isradipine on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition. Psychopharmacology, 178, 296-302.
    • (2005) Psychopharmacology , vol.178 , pp. 296-302
    • Johnson, B.A.1    Roache, J.D.2    Ait-Daoud, N.3    Wallace, C.4    Wells, L.T.5    Wang, Y.6
  • 31
    • 19744362939 scopus 로고    scopus 로고
    • Isradipine decreases the hemodynamic response of cocaine and methamphetamine: Results from two human laboratory studies
    • Johnson, B. A., Wells, L. T., Roache, J. D., Wallace, C., Ait-Daoud, N., & Wang, Y. (2005). Isradipine decreases the hemodynamic response of cocaine and methamphetamine: Results from two human laboratory studies. American Journal on Hypertension, 18, 813-822.
    • (2005) American Journal on Hypertension , vol.18 , pp. 813-822
    • Johnson, B.A.1    Wells, L.T.2    Roache, J.D.3    Wallace, C.4    Ait-Daoud, N.5    Wang, Y.6
  • 32
    • 33751256950 scopus 로고    scopus 로고
    • Monitoring the future: National survey results on drug use, 1975-2003: Vol. 1. Secondary school students
    • Bethesda, MD: National Institute on Drug Abuse
    • Johnston, L. D., O'Malley, P. M., Bachman, J. G., & Schulenberg, J. E. (2004). Monitoring the future: National survey results on drug use, 1975-2003: Vol. 1. Secondary school students (NIH Publication No. 04-5507). Bethesda, MD: National Institute on Drug Abuse.
    • (2004) NIH Publication No. 04-5507
    • Johnston, L.D.1    O'Malley, P.M.2    Bachman, J.G.3    Schulenberg, J.E.4
  • 33
    • 0001517212 scopus 로고
    • Pharmacological blockade of amphetamine effects in amphetamine dependent subjects
    • Jonsson, L. (1972). Pharmacological blockade of amphetamine effects in amphetamine dependent subjects. European Journal of Clinical Pharmacology, 4, 206-211.
    • (1972) European Journal of Clinical Pharmacology , vol.4 , pp. 206-211
    • Jonsson, L.1
  • 38
    • 0015026728 scopus 로고
    • Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man
    • Martin, W. R., Sloan, J. W., Sapira, J. D., & Jasinski, D. R. (1971). Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man. Clinical Pharmacology and Therapeutics, 12, 245-258.
    • (1971) Clinical Pharmacology and Therapeutics , vol.12 , pp. 245-258
    • Martin, W.R.1    Sloan, J.W.2    Sapira, J.D.3    Jasinski, D.R.4
  • 41
    • 33747344749 scopus 로고    scopus 로고
    • Dissociation between in vivo occupancy and functional antagonism of dopamine D(2) receptors: Comparing aripiprazole to other antipsychotics in animal models
    • Natesan, S., Reckless, G. E., Nobrega, J. N., Fletcher, P. J., & Kapur, S. (2006). Dissociation between in vivo occupancy and functional antagonism of dopamine D(2) receptors: Comparing aripiprazole to other antipsychotics in animal models. Neuropsychopharmacology, 31, 1854-1863.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1854-1863
    • Natesan, S.1    Reckless, G.E.2    Nobrega, J.N.3    Fletcher, P.J.4    Kapur, S.5
  • 42
    • 33751221696 scopus 로고
    • National Household Survey on Drug Abuse. Retrieved September 20, 2006, from
    • National Household Survey on Drug Abuse. (1994). NHSDA, Advance Report No. 10. Retrieved September 20, 2006, from http://oas.samhsa.gov/p0000016. htm#1994
    • (1994) NHSDA, Advance Report No. 10
  • 43
    • 15844417337 scopus 로고    scopus 로고
    • National Survey on Drug Use and Health. Retrieved November 29, 2004, from
    • National Survey on Drug Use and Health. (2004). Results of the 2003 National Survey on Drug Use and Health. Retrieved November 29, 2004, from http://oas.samhsa.gov/nhsda/ 2k3nsduh/2k3Overview.htm#toc
    • (2004) Results of the 2003 National Survey on Drug Use and Health
  • 44
    • 34250362050 scopus 로고    scopus 로고
    • National Survey on Drug Use and Health. Retrieved April 3, 2006, from
    • National Survey on Drug Use and Health. (2005). Methamphetamine use, abuse, and dependence. Retrieved April 3, 2006, from http://oas.samhsa.gov/2k5/ meth/meth.cfm
    • (2005) Methamphetamine Use, Abuse, and Dependence
  • 45
    • 31844433206 scopus 로고    scopus 로고
    • A comprehensive assessment of the safety of intravenous methamphetamine administration during treatment with selegiline
    • Newton, T. F., De La Garza, R., II, Fong, T., Chiang, N., Holmes, T. H., Bloch, D. A., et al. (2005). A comprehensive assessment of the safety of intravenous methamphetamine administration during treatment with selegiline. Pharmacology Biochemistry and Behavior, 82, 704-711.
    • (2005) Pharmacology Biochemistry and Behavior , vol.82 , pp. 704-711
    • Newton, T.F.1    De La Garza II, R.2    Fong, T.3    Chiang, N.4    Holmes, T.H.5    Bloch, D.A.6
  • 46
    • 26844523262 scopus 로고    scopus 로고
    • Safety of intravenous methamphetamine administration during treatment with bupropion
    • Newton, T. F., Roache, J. D., De La Garza, R., II, Fong, T., Wallace, C. L., Li, S. H., et al. (2005). Safety of intravenous methamphetamine administration during treatment with bupropion. Psychopharmacology, 182, 426-435.
    • (2005) Psychopharmacology , vol.182 , pp. 426-435
    • Newton, T.F.1    Roache, J.D.2    De La Garza II, R.3    Fong, T.4    Wallace, C.L.5    Li, S.H.6
  • 48
    • 0021889611 scopus 로고
    • Antagonism of the amphetamine cue by both classical and atypical antipsychotic drugs
    • Nielsen, E. B., & Jepsen, S. A. (1985). Antagonism of the amphetamine cue by both classical and atypical antipsychotic drugs. European Journal of Pharmacology, 111, 167-176.
    • (1985) European Journal of Pharmacology , vol.111 , pp. 167-176
    • Nielsen, E.B.1    Jepsen, S.A.2
  • 51
    • 0029120432 scopus 로고
    • Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine
    • Parsons, L. H., Koob, G. F., & Weiss, F. (1995). Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine. Journal of Pharmacology and Experimental Therapeutics, 274, 1182-1191.
    • (1995) Journal of Pharmacology and Experimental Therapeutics , vol.274 , pp. 1182-1191
    • Parsons, L.H.1    Koob, G.F.2    Weiss, F.3
  • 54
    • 0035218082 scopus 로고    scopus 로고
    • Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
    • Rothman, R. B., Baumann, M. H., Dersch, C. M., Romero, D. V., Rice, K. C., Carroll, F. I., & Partilla, J. S. (2001). Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse, 39, 32-41.
    • (2001) Synapse , vol.39 , pp. 32-41
    • Rothman, R.B.1    Baumann, M.H.2    Dersch, C.M.3    Romero, D.V.4    Rice, K.C.5    Carroll, F.I.6    Partilla, J.S.7
  • 56
  • 57
    • 0019274283 scopus 로고
    • The effect of the dopamine receptor blocking drug pimozide on the stimulant and anorectic actions of dextroamphetamine in man
    • Silverstone, T., Fincham, J., Wells, B., & Kyriakides, M. (1980). The effect of the dopamine receptor blocking drug pimozide on the stimulant and anorectic actions of dextroamphetamine in man. Neuropharmacology, 19, 1235-1237.
    • (1980) Neuropharmacology , vol.19 , pp. 1235-1237
    • Silverstone, T.1    Fincham, J.2    Wells, B.3    Kyriakides, M.4
  • 58
    • 33746324268 scopus 로고    scopus 로고
    • A low dose of aripiprazole attenuates the subject-rated effects of d-amphetamine
    • Stoops, W. W., Lile, J. A., Glaser, P. E. A., & Rush, C. R. (2006). A low dose of aripiprazole attenuates the subject-rated effects of d-amphetamine. Drug and Alcohol Dependence, 84, 206-209.
    • (2006) Drug and Alcohol Dependence , vol.84 , pp. 206-209
    • Stoops, W.W.1    Lile, J.A.2    Glaser, P.E.A.3    Rush, C.R.4
  • 60
    • 0035576119 scopus 로고    scopus 로고
    • Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence
    • Volkow, N. D., Chang, L., Wang, G. J., Fowler, J. S., Franceschi, D., Sedler, M., et al. (2001). Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence. Journal of Neuroscience, 21, 9414-9418.
    • (2001) Journal of Neuroscience , vol.21 , pp. 9414-9418
    • Volkow, N.D.1    Chang, L.2    Wang, G.J.3    Fowler, J.S.4    Franceschi, D.5    Sedler, M.6
  • 61
    • 0036708074 scopus 로고    scopus 로고
    • The effects of acute haloperidol or risperidone on subjective responses to methamphetamine in healthy volunteers
    • Wachtel, S. R., Ortengren, A., & de Wit, H. (2002). The effects of acute haloperidol or risperidone on subjective responses to methamphetamine in healthy volunteers. Drug and Alcohol Dependence, 68, 23-33.
    • (2002) Drug and Alcohol Dependence , vol.68 , pp. 23-33
    • Wachtel, S.R.1    Ortengren, A.2    De Wit, H.3
  • 62
    • 0034807831 scopus 로고    scopus 로고
    • Enadoline and butorphanol: Evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans
    • Walsh, S. L., Geter-Douglas, B., Strain, E. C., & Bigelow, G. E. (2001). Enadoline and butorphanol: Evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans. Journal of Pharmacology and Experimental Therapeutics, 299, 147-158.
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.299 , pp. 147-158
    • Walsh, S.L.1    Geter-Douglas, B.2    Strain, E.C.3    Bigelow, G.E.4
  • 63
    • 0026663188 scopus 로고
    • Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration
    • Weiss, F., Markou, A., Lorang, M. T., & Koob, G. F. (1992). Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain Research, 593, 314-318.
    • (1992) Brain Research , vol.593 , pp. 314-318
    • Weiss, F.1    Markou, A.2    Lorang, M.T.3    Koob, G.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.