Cell-specific differential modulation of human trabecular meshwork cells by selective adenosine receptor agonists

Experimental Eye Research

Volumn 84, Issue 1, 2007, Pages 126-134

  Karl, Mike O ^a   Peterson Yantorno, Kim ^a   Civan, Mortimer M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

aqueous humor outflow; cell volume regulation; intraocular pressure; ion transport

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE RECEPTOR STIMULATING AGENT;

AQUEOUS HUMOR; ARTICLE; CELL DIFFERENTIATION; CELL POPULATION; CELL SPECIFICITY; CELL VOLUME; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FLUORESCENCE; HUMAN; HUMAN CELL; INTRAOCULAR PRESSURE; ION TRANSPORT; PRIORITY JOURNAL; RECEPTOR BINDING; TRABECULAR MESHWORK;

AQUEOUS HUMOR; CALCIUM; CELL SIZE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; ION TRANSPORT; PATCH-CLAMP TECHNIQUES; POTASSIUM; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; TRABECULAR MESHWORK;

EID: 33751243592     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2006.09.007     Document Type: Article

References (49)

1. Al-Aswad L.A., Gong H., Lee D., O'Donnell M.E., Brandt J.D., Ryan W.J., Schroeder A., and Erickson K.A. Effects of Na-K-2Cl cotransport regulators on outflow facility in calf and human eyes in vitro. Invest. Ophthalmol. Vis. Sci. 40 (1999) 1695-1701
2. Avila M.Y., Carré D.A., Stone R.A., and Civan M.M. Reliable measurement of mouse intraocular pressure by a servo-null micropipette system. Invest. Ophthalmol. Vis. Sci. 42 (2001) 1841-1846
3. Avila M.Y., Stone R.A., and Civan M.M. A(1)-, A(2A)- and A(3)-subtype adenosine receptors modulate intraocular pressure in the mouse. Br J Pharmacol 134 (2001) 241-245
4. Avila M.Y., Seidler R.W., Stone R.A., and Civan M.M. Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure. Invest. Ophthalmol. Vis. Sci. 43 (2002) 1897-1902
5. Avila M.Y., Stone R.A., and Civan M.M. Knockout of A(3) adenosine receptors reduces mouse intraocular pressure. Invest. Ophthalmol. Vis. Sci. 43 (2002) 3021-3026
6. Carré D.A., Mitchell C.H., Peterson-Yantorno K., Coca-Prados M., and Civan M.M. Similarity of A(3)-adenosine and swelling-activated Cl(-) channels in nonpigmented ciliary epithelial cells. Am. J. Physiol. Cell Physiol 279 (2000) C440-C451
7. Civan M.M., and Macknight A.D. The ins and outs of aqueous humour secretion. Exp. Eye Res. 78 (2004) 625-631
8. Civan M.M., McLaughlin C.W., Zellhuber-Macmillan S., Karl M., Wang Z., and Macknight A.D.C. Electron Probe X-Ray Microanalyses of Cells in Schlemm'S Canal, Juxtacanalicular Tissue and Trabecular Meshwork of Intact Human Tissue. Invest. Ophthalmol. Vis. Sci. 47 (2006) 408
9. Crook R.B., Takahashi K., Mead A., Dunn J.J., and Sears M.L. The role of NaKCl cotransport in blood-to-aqueous chloride fluxes across rabbit ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 41 (2000) 2574-2583
10. Crosson C.E. Adenosine receptor activation modulates intraocular pressure in rabbits. J. Pharmacol. Exp. Ther. 273 (1995) 320-326
11. Crosson C.E. Intraocular pressure responses to the adenosine agonist cyclohexyladenosine: evidence for a dual mechanism of action. Invest. Ophthalmol. Vis. Sci. 42 (2001) 1837-1840
12. Crosson C.E., and Gray T. Characterization of ocular hypertension induced by adenosine agonists. Invest. Ophthalmol. Vis. Sci. 37 (1996) 1833-1839
13. de Kater A.W., Spurr-Michaud S.J., and Gipson I.K. Localization of smooth muscle myosin-containing cells in the aqueous outflow pathway. Invest. Ophthalmol. Vis. Sci. 31 (1990) 347-353
14. de Zwart M., Link R., von Frijtag Drabbe Kunzel J.K., Cristalli G., Jacobson K.A., Townsend-Nicholson A., and Ijzerman A.P. A functional screening of adenosine analogues at the adenosine A2B receptor: a search for potent agonists. Nucleosides Nucleotides 17 (1998) 969-985
15. Do C.W., and Civan M.M. Basis of chloride transport in ciliary epithelium. J. Membr. Biol. 200 (2004) 1-13
16. Do C.W., Peterson-Yantorno K., and Civan M.M. Swelling-activated Cl- channels support Cl- secretion by bovine ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 47 (2006) 2576-2582
17. Do C.W., Peterson-Yantorno K., Mitchell C.H., and Civan M.M. cAMP-activated maxi-Cl(-) channels in native bovine pigmented ciliary epithelial cells. Am. J. Physiol. Cell Physiol. 287 (2004) C1003-C1011
18. Engelmann K., and Friedl P. Optimization of culture conditions for human corneal endothelial cells. In Vitro Cell Dev. Biol. 25 (1989) 1065-1072
19. Epsztejn S., Kakhlon O., Glickstein H., Breuer W., and Cabantchik I. Fluorescence analysis of the labile iron pool of mammalian cells. Anal. Biochem. 248 (1997) 31-40
20. Ethier C.R. The inner wall of Schlemm's canal. Exp. Eye Res. 74 (2002) 161-172
21. Fleischhauer J.C., Mitchell C.H., Stamer W.D., Karl M.O., Peterson-Yantorno K., and Civan M.M. Common actions of adenosine receptor agonists in modulating human trabecular meshwork cell transport. J. Membr. Biol. 193 (2003) 121-136
22. Fredholm B.B., Ijzerman A.P., Jacobson K.A., Klotz K.N., and Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol. Rev. 53 (2001) 527-552
23. Fredholm B.B., Irenius E., Kull B., and Schulte G. Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells. Biochem. Pharmacol 61 (2001) 443-448
24. Gasull X., Ferrer E., Llobet A., Castellano A., Nicolas J.M., Pales J., and Gual A. Cell membrane stretch modulates the high-conductance Ca2+-activated K+ channel in bovine trabecular meshwork cells. Invest. Ophthalmol. Vis. Sci. 44 (2003) 706-714
25. Grosheva I., Vittitow J.L., Goichberg P., Gabelt B.T., Kaufman P.L., Borras T., Geiger B., and Bershadsky A.D. Caldesmon effects on the actin cytoskeleton and cell adhesion in cultured HTM cells. Exp. Eye Res. 82 (2006) 945-958
26. Grynkiewicz G., Poenie M., and Tsien R.Y. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260 (1985) 3440-3450
27. Gual A., Llobet A., Gilabert R., Borras M., Pales J., Bergamini M.V., and Belmonte C. Effects of time of storage, albumin, and osmolality changes on outflow facility (C) of bovine anterior segment in vitro. Invest. Ophthalmol. Vis. Sci. 38 (1997) 2165-2171
28. Haas H.L., and Selbach O. Functions of neuronal adenosine receptors. Naunyn Schmiedebergs Arch. Pharmacol. 362 (2000) 375-381
29. Hamann S., Kiilgaard J.F., Litman T., Alvarez-Leefmans F.J., Winther B.R., and Zeuthen T. Measurement of cell volume changes by fluorescence self-quenching. J. Fluoresc. 12 (2002) 139-145
30. Howard G.C., Roberts B.C., Epstein D.L., and Pizzo S.V. Characterization of alpha 2-macroglobulin binding to human trabecular meshwork cells: presence of the alpha 2-macroglobulin signaling receptor. Arch. Biochem. Biophys. 333 (1996) 19-26
31. Jacobson K.A., and Gao Z.G. Adenosine receptors as therapeutic targets. Nat. Rev. Drug Discov. 5 (2006) 247-264
32. Jacobson K.A., and Knutsen L.J.S. P1 and P2 Purine and Pyrimidine receptor ligands. In: Abbracchio M.P., and Williams M. (Eds). Purinergic and Pyrimidinergic Signalling (2001), Springer, New York 129-175
33. Johnson M. What controls aqueous humour outflow resistance?. Exp. Eye Res. 82 (2006) 545-557
34. Johnson M., and Erickson K. Mechanism and Routes of Aqueous Humor Drainage. In: Albert D.M., and Jakobiec F.A. (Eds) (2000), Principles and Practice of Ophthalmology.Saunders, Philadelphia 2577-2595
35. Karl M.O., Fleischhauer J.C., Stamer W.D., Peterson-Yantorno K., Mitchell C.H., Stone R.A., and Civan M.M. Differential P1-purinergic modulation of human Schlemm's canal inner-wall cells. Am. J. Physiol. Cell Physiol. 288 (2005) C784-C794
36. Klotz K.N. Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch Pharmacol 362 (2000) 382-391
37. Lorentzen A., and Schwabe U. P1 receptors. In: Abbrachio M.P., and Williams M. (Eds). Purinergic and Pyrimidinergic Signaling I: Molecular, Nervous and Urogenitary System Function (2001), Springer, Berlin/Heidelberg/New York 19-45 chapter 2
38. Mitchell C.H., Fleischhauer J.C., Stamer W.D., Peterson-Yantorno K., and Civan M.M. Human trabecular meshwork cell volume regulation. Am. J. Physiol. 283 (2002) C315-C326
39. O'Donnell M.E., Brandt J.D., and Curry F.R. Na-K-Cl cotransport regulates intracellular volume and monolayer permeability of trabecular meshwork cells. Am. J. Physiol. 268 (1995) C1067-C1074
40. Pang I.H., Shade D.L., Clark A.F., Steely H.T., and DeSantis L. Preliminary characterization of a transformed cell strain derived from human trabecular meshwork. Curr. Eye Res. 13 (1994) 51-63
41. Raviola G., and Raviola E. Intercellular junctions in the ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 17 (1978) 958-981
42. Rohen J.W. Experimental studies on the trabecular meshwork in primates. Arch. Ophthalmol. 69 (1963) 91-105
43. Schlötzer-Schrehardt U., Zenkel M., Decking U., Haubs D., Kruse F.E., Junemann A., Coca-Prados M., and Naumann G.O. Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma. Invest. Ophthalmol. Vis. Sci. 46 (2005) 2023-2034
44. Shearer T.W., and Crosson C.E. Adenosine A1 receptor modulation of MMP-2 secretion by trabecular meshwork cells. Invest. Ophthalmol. Vis. Sci. 43 (2002) 3016-3020
45. Solenov E., Watanabe H., Manley G.T., and Verkman A.S. Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method. Am. J. Physiol. Cell Physiol. 286 (2004) C426-C432
46. Stumpff F., Strauss O., Boxberger M., and Wiederholt M. Characterization of maxi-K-channels in bovine trabecular meshwork and their activation by cyclic guanosine monophosphate. Invest. Ophthalmol. Vis. Sci. 38 (1997) 1883-1892
47. Tian B., Gabelt B.T., Crosson C.E., and Kaufman P.L. Effects of adenosine agonists on intraocular pressure and aqueous humor dynamics in cynomolgus monkeys. Exp. Eye Res. 64 (1997) 979-989
48. To C.H., Do C.W., Zamudio A.C., and Candia O.A. Model of ionic transport for bovine ciliary epithelium: effects of acetazolamide and HCO. Am. J. Physiol. Cell Physiol. 280 (2001) C1521-C1530
49. Walker V.E., Stelling J.W., Miley H.E., and Jacob T.J. Effect of coupling on volume-regulatory response of ciliary epithelial cells suggests mechanism for secretion. Am. J. Physiol. 276 (1999) C1432-C1438