메뉴 건너뛰기




Volumn 82, Issue 972, 2006, Pages 658-662

Tibolone and breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; CONJUGATED ESTROGEN; CYPROTERONE ACETATE; ESTRADIOL; ESTRADIOL VALERATE; ESTROGEN; ESTROGEN RECEPTOR; ETHINYLESTRADIOL; MEDROXYPROGESTERONE ACETATE; NOMEGESTROL; NORETHISTERONE ACETATE; PROGESTERONE; PROGESTERONE RECEPTOR; RALOXIFENE; TAMOXIFEN; TIBOLONE;

EID: 33751226923     PISSN: 00325473     EISSN: None     Source Type: Journal    
DOI: 10.1136/pgmj.2005.037184     Document Type: Review
Times cited : (11)

References (46)
  • 1
    • 0035977602 scopus 로고    scopus 로고
    • Tibolone. What does tissue specific activity mean?
    • Palocios S. Tibolone. What does tissue specific activity mean? Maturitas 2001;37:159-05.
    • (2001) Maturitas , vol.37 , pp. 159-205
    • Palocios, S.1
  • 2
    • 0034987346 scopus 로고    scopus 로고
    • Tibolone: A steroid with a tissue-specific mode of action
    • Kloosterboer HJ. Tibolone: a steroid with a tissue-specific mode of action. Steroid Biochem Mol Biol 2001;76:231-8.
    • (2001) Steroid Biochem Mol Biol , vol.76 , pp. 231-238
    • Kloosterboer, H.J.1
  • 3
    • 0027216228 scopus 로고
    • Human endometrial 3α-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic/ progestagenic activity ratios of a steroidal drug (OrgOD14)
    • Tang BLK, Markiewicz HJ, Gurpide E. Human endometrial 3α-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic/ progestagenic activity ratios of a steroidal drug (OrgOD14). J Steroid Biochem Mol Biol 1993;45:345-51.
    • (1993) J Steroid Biochem Mol Biol , vol.45 , pp. 345-351
    • Tang, B.L.K.1    Markiewicz, H.J.2    Gurpide, E.3
  • 4
    • 0028212467 scopus 로고
    • Estrogenic and progestagenic activities coexisting in steroidal drugs: Quantitative evaluation by in vitro bioassays with human cells
    • Markiewicz L, Gurpide E. Estrogenic and progestagenic activities coexisting in steroidal drugs: quantitative evaluation by in vitro bioassays with human cells. J Steroid Biochem Mol Biol 1994;48:89-94.
    • (1994) J Steroid Biochem Mol Biol , vol.48 , pp. 89-94
    • Markiewicz, L.1    Gurpide, E.2
  • 5
    • 0036146189 scopus 로고    scopus 로고
    • Tibolone for postmenopausal women: Systematic review of randomized trial
    • Modelska K, Cummings S. Tibolone for postmenopausal women: systematic review of randomized trial. J Clin Endocrinol Metab 2002;87:16-23.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 16-23
    • Modelska, K.1    Cummings, S.2
  • 6
    • 18044372636 scopus 로고    scopus 로고
    • Recent insight on lhe control of enzymes involved in estrogen formation and transformation in human breast cancer
    • Pasqualini JR, Chetrite GS. Recent insight on lhe control of enzymes involved in estrogen formation and transformation in human breast cancer. J Steroid Biochem Mol Biol 2005;93:221-36.
    • (2005) J Steroid Biochem Mol Biol , vol.93 , pp. 221-236
    • Pasqualini, J.R.1    Chetrite, G.S.2
  • 7
    • 0031050931 scopus 로고    scopus 로고
    • Effect of tibolone (Org OD14) and ils metabolites on estrone sulphatase activity in MCF-7 and T-47D mammary cancer cells
    • Cherite G, Kloosterboer HJ, Pasqualini JR. Effect of tibolone (Org OD14) and ils metabolites on estrone sulphatase activity in MCF-7 and T-47D mammary cancer cells. Anticancer Res 1997;17:135-40.
    • (1997) Anticancer Res , vol.17 , pp. 135-140
    • Cherite, G.1    Kloosterboer, H.J.2    Pasqualini, J.R.3
  • 8
    • 0001821273 scopus 로고    scopus 로고
    • Estrone sulfatase and 17β-hydroxysteroid dehydrogenase activities in human breast cancer. Inhibitory effect by tibolone and its metabolites
    • Pasqualini JR, Kloosterboer HJ. Estrone sulfatase and 17β-hydroxysteroid dehydrogenase activities in human breast cancer. Inhibitory effect by tibolone and its metabolites. Acta Obstet Gynaecol Scand 1997;76(Suppl 167):35.
    • (1997) Acta Obstet Gynaecol Scand , vol.76 , Issue.SUPPL. 167 , pp. 35
    • Pasqualini, J.R.1    Kloosterboer, H.J.2
  • 9
    • 0032921646 scopus 로고    scopus 로고
    • Effect of Org OD14 (Livial®) and its metabolites on human estrogen sulphotransferase activity in the hormone-dependent MCF-7 and T- 47D, and the hormone independent MDA-MB-231, breast cancer cells lines
    • Chetrite GS, Klcosterboer HJ, Philippe JC, et al. Effect of Org OD14 (Livial®) and its metabolites on human estrogen sulphotransferase activity in the hormone-dependent MCF-7 and T- 47D, and the hormone independent MDA-MB-231, breast cancer cells lines. Anticancer Res 1999;19:269-76.
    • (1999) Anticancer Res , vol.19 , pp. 269-276
    • Chetrite, G.S.1    Klcosterboer, H.J.2    Philippe, J.C.3
  • 10
    • 0036328330 scopus 로고    scopus 로고
    • In vitro studies of tibolone in breast cells
    • Gompel A, Chaouat M, Jacob D, et al. In vitro studies of tibolone in breast cells. Fertil Steril 2002;78:351-9.
    • (2002) Fertil Steril , vol.78 , pp. 351-359
    • Gompel, A.1    Chaouat, M.2    Jacob, D.3
  • 11
    • 23744474476 scopus 로고    scopus 로고
    • Effect of 17β-estradiol, progesterone, synthetic progestins, tibolone, and tibolone metabolites on vascular endothelial growth factor mRNA in breast cancer cells
    • Mirkin S, Wong BC, Archer DF. Effect of 17β-estradiol, progesterone, synthetic progestins, tibolone, and tibolone metabolites on vascular endothelial growth factor mRNA in breast cancer cells. Fertil Steril 2005;84:485-91.
    • (2005) Fertil Steril , vol.84 , pp. 485-491
    • Mirkin, S.1    Wong, B.C.2    Archer, D.F.3
  • 12
    • 0037333156 scopus 로고    scopus 로고
    • Tibolone is not converted by human aromatase to 7α-methyl- 17α-ethynylestradiol (7α-MEE): Analyses with sensitive bioassays for estrogens and androgens and with LC-MS/MS
    • Gooyer de ME, Oppers-Tiemissen HM, Leysen D, et al. Tibolone is not converted by human aromatase to 7α-methyl-17α-ethynylestradiol (7α-MEE): analyses with sensitive bioassays for estrogens and androgens and with LC-MS/MS. Steroids 2003;68:235-43.
    • (2003) Steroids , vol.68 , pp. 235-243
    • De Gooyer, M.E.1    Oppers-Tiemissen, H.M.2    Leysen, D.3
  • 13
    • 0036348830 scopus 로고    scopus 로고
    • Effect of tibolone (Org OD14) and its metabolites on aromatase and estrone sulfatase activity in human breast adipose stromal cells and in MCF-7 and T47D breast cancer cells
    • van de Ven J, Donker G, Sprang M, et al. Effect of tibolone (Org OD14) and its metabolites on aromatase and estrone sulfatase activity in human breast adipose stromal cells and in MCF-7 and T47D breast cancer cells. J Steroid Biochem Mol Biol 2002;81:237-47.
    • (2002) J Steroid Biochem Mol Biol , vol.81 , pp. 237-247
    • Van De Ven, J.1    Donker, G.2    Sprang, M.3
  • 14
    • 0036010339 scopus 로고    scopus 로고
    • Tibolone versus 17beta-estradiol/ norethislerone: Effects on the proliferation of human breast cancer cells, fur 1
    • Lippert C, Seeger H, Wallwiener D, et al. Tibolone versus 17beta-estradiol/ norethislerone: effects on the proliferation of human breast cancer cells, fur 1 Gynaecol Oncol 2002;23:127-30.
    • (2002) Gynaecol Oncol , vol.23 , pp. 127-130
    • Lippert, C.1    Seeger, H.2    Wallwiener, D.3
  • 15
  • 16
    • 25444468815 scopus 로고    scopus 로고
    • Hormonal environment in the induction of breast cancer in castrated rats using dimethylbenzanthracene: Influence of the presence or absence of ovarian activity and of treatment with estradiol, tibolone, and raloxifene
    • Caline J, Cono A, Medina M, et al. Hormonal environment in the induction of breast cancer in castrated rats using dimethylbenzanthracene: influence of the presence or absence of ovarian activity and of treatment with estradiol, tibolone, and raloxifene. Menopause 2005;12:601-8.
    • (2005) Menopause , vol.12 , pp. 601-608
    • Caline, J.1    Cono, A.2    Medina, M.3
  • 17
    • 0036834499 scopus 로고    scopus 로고
    • Effects of tibolone and hormone replacement therapy on the breast of cynomolgus monkeys
    • Cline JM, Register TC, Clarkson TB. Effects of tibolone and hormone replacement therapy on the breast of cynomolgus monkeys. Menopause 2002;9:422-9.
    • (2002) Menopause , vol.9 , pp. 422-429
    • Cline, J.M.1    Register, T.C.2    Clarkson, T.B.3
  • 18
    • 22244432847 scopus 로고    scopus 로고
    • Expression of p53 and markers for apoptosis in breast tissue during long-term hormone therapy in cynomolgus monkeys
    • Conner P, Register PC, Skoog L, et al. Expression of p53 and markers for apoptosis in breast tissue during long-term hormone therapy in cynomolgus monkeys. Am J Obstet Gynecol 2005;193:58-63.
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 58-63
    • Conner, P.1    Register, P.C.2    Skoog, L.3
  • 19
    • 23744446092 scopus 로고    scopus 로고
    • The effect of hormone replacement therapy on recall rate in the National Health Service Breast Screening Programme
    • Litherland JC, Evans AJ, Wilson AR. The effect of hormone replacement therapy on recall rate in the National Health Service Breast Screening Programme. Clin Radiol 1997;52:276-9.
    • (1997) Clin Radiol , vol.52 , pp. 276-279
    • Litherland, J.C.1    Evans, A.J.2    Wilson, A.R.3
  • 20
    • 0032935148 scopus 로고    scopus 로고
    • The effect of hormone replacement therapy on the sensitivity of screening mammograms
    • Limerland JC, Stallard S, Hole D, et al. The effect of hormone replacement therapy on the sensitivity of screening mammograms. Clin Radiol 1999;54:285-8.
    • (1999) Clin Radiol , vol.54 , pp. 285-288
    • Limerland, J.C.1    Stallard, S.2    Hole, D.3
  • 21
    • 0005764351 scopus 로고    scopus 로고
    • Mammographic densities and the prevalence and incidence of histological types of benign breast disease
    • Boyd NF, Jensen HM, Cooke G, et al. Mammographic densities and the prevalence and incidence of histological types of benign breast disease. Eur J Cancer Prev 2000;9:15-24.
    • (2000) Eur J Cancer Prev , vol.9 , pp. 15-24
    • Boyd, N.F.1    Jensen, H.M.2    Cooke, G.3
  • 22
    • 1642377145 scopus 로고    scopus 로고
    • Effect of tibolone and continuous combined hormone replacement therapy on mammographic breast density and breast histochemical markers in postmenopausal women
    • Valdivia I, Campodónico I, Tapia A, et al. Effect of tibolone and continuous combined hormone replacement therapy on mammographic breast density and breast histochemical markers in postmenopausal women. Fertil Steril 2004;81:617-23.
    • (2004) Fertil Steril , vol.81 , pp. 617-623
    • Valdivia, I.1    Campodónico, I.2    Tapia, A.3
  • 23
    • 1642401373 scopus 로고    scopus 로고
    • A comparative study on breast cell proliferation during HRT effects of tibolone and continuous combined estrogen progestogen treatment
    • Conner P, Christow A, Kersemaekers W. A comparative study on breast cell proliferation during HRT effects of tibolone and continuous combined estrogen progestogen treatment. Climacteric 2004;7:50-8.
    • (2004) Climacteric , vol.7 , pp. 50-58
    • Conner, P.1    Christow, A.2    Kersemaekers, W.3
  • 24
    • 0030218936 scopus 로고    scopus 로고
    • Mammographic changes in women on hormonal replacement therapy
    • Erel CT, Seyisoǧlu H, Şentürk ML, et al. Mammographic changes in women on hormonal replacement therapy. Maturitas 1996;25:51-7.
    • (1996) Maturitas , vol.25 , pp. 51-57
    • Erel, C.T.1    Seyisoǧlu, H.2    Şentürk, M.L.3
  • 25
    • 0033574030 scopus 로고    scopus 로고
    • Effects of estrogen and estrogenprogestin on mammographic parenchymal density
    • Postmenopausal Estrogen/Progestin Interventions (PEPI) Investigators
    • Greendate GA, Reboussin BA, Sie A, et al. Effects of estrogen and estrogenprogestin on mammographic parenchymal density. Postmenopausal Estrogen/Progestin Interventions (PEPI) Investigators. Ann Intern Med 1999;130:262-9.
    • (1999) Ann Intern Med , vol.130 , pp. 262-269
    • Greendate, G.A.1    Reboussin, B.A.2    Sie, A.3
  • 26
    • 0032878847 scopus 로고    scopus 로고
    • Mammographic breast density during hormone replacement therapy: Differences according to treatment
    • Lundstrom E, Wilczek B, vonPalffy Z, et al. Mammographic breast density during hormone replacement therapy: differences according to treatment. Am J Obstet Gynecol 1999;181:348-52.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 348-352
    • Lundstrom, E.1    Wilczek, B.2    Vonpalffy, Z.3
  • 27
    • 0034893493 scopus 로고    scopus 로고
    • Mammographic density changes during different postmenopausal hormone replacement therapies
    • Sendag F, Cosan Terek M, Ozsener S, et al. Mammographic density changes during different postmenopausal hormone replacement therapies, Fertil Steril 2001;76:445-50.
    • (2001) Fertil Steril , vol.76 , pp. 445-450
    • Sendag, F.1    Cosan Terek, M.2    Ozsener, S.3
  • 28
    • 0035976467 scopus 로고    scopus 로고
    • Mammographic density increase in women receiving different hormone replacement regimens
    • Erel CT, Esen G, Seyisoglu H, et al. Mammographic density increase in women receiving different hormone replacement regimens. Maturitas 2001;40:151-7.
    • (2001) Maturitas , vol.40 , pp. 151-157
    • Erel, C.T.1    Esen, G.2    Seyisoglu, H.3
  • 29
    • 0035026888 scopus 로고    scopus 로고
    • Mammographic breast density during hormone replacement therapy: Efects of continuous combination, unopposed transdermal and low-potency estrogen regimens
    • Lundstrom E, Wilczek B, von Palffy Z, et al. Mammographic breast density during hormone replacement therapy: efects of continuous combination, unopposed transdermal and low-potency estrogen regimens. Climacteric 2001;4:42-8.
    • (2001) Climacteric , vol.4 , pp. 42-48
    • Lundstrom, E.1    Wilczek, B.2    Von Palffy, Z.3
  • 30
    • 0034892490 scopus 로고    scopus 로고
    • Effects of a short-term suspension of hormone replacement therapy on mammographic density
    • Colacurci N, Fornaro F, DeFranciscis P, et al. Effects of a short-term suspension of hormone replacement therapy on mammographic density. Fertil Steril 2001;76:451-5.
    • (2001) Fertil Steril , vol.76 , pp. 451-455
    • Colacurci, N.1    Fornaro, F.2    DeFranciscis, P.3
  • 31
    • 0032080247 scopus 로고    scopus 로고
    • Mammographic changes in women receiving tibolone therapy
    • Erel CT, Eiter K, Akman C, et al. Mammographic changes in women receiving tibolone therapy. Fertil Steril 1998;69:870-5.
    • (1998) Fertil Steril , vol.69 , pp. 870-875
    • Erel, C.T.1    Eiter, K.2    Akman, C.3
  • 33
    • 0032727094 scopus 로고    scopus 로고
    • Mammographic and ultrasonographic study of changes in the breast related to HRT
    • Ozdemir A, Konus O, Nas T, et al. Mammographic and ultrasonographic study of changes in the breast related to HRT. Int J Gynaecol Obstet 1999;67:23-32.
    • (1999) Int J Gynaecol Obstet , vol.67 , pp. 23-32
    • Ozdemir, A.1    Konus, O.2    Nas, T.3
  • 34
    • 0035976495 scopus 로고    scopus 로고
    • Effects of different types of hormone replacement therapy on mammographic density
    • Colocurci N, Fornaro F, De Franciscis P, et al. Effects of different types of hormone replacement therapy on mammographic density. Maturitas 2001;40:159-64.
    • (2001) Maturitas , vol.40 , pp. 159-164
    • Colocurci, N.1    Fornaro, F.2    De Franciscis, P.3
  • 35
    • 0035976489 scopus 로고    scopus 로고
    • A pilot study of hormone replacement therapy with tibolone in women with mastopathic breasts
    • Egarter C, Eppel W, Vogel S, et al. A pilot study of hormone replacement therapy with tibolone in women with mastopathic breasts. Maturitas 2001;40:165-71.
    • (2001) Maturitas , vol.40 , pp. 165-171
    • Egarter, C.1    Eppel, W.2    Vogel, S.3
  • 36
    • 0036264710 scopus 로고    scopus 로고
    • Effects of tibolone and continuous combined hormone replacement therapy on mammographic breast density
    • Lundstrom E, Christow A, Kersemaekers W, et al. Effects of tibolone and continuous combined hormone replacement therapy on mammographic breast density. Am J Obstet Gynecol 2002;186:717-22.
    • (2002) Am J Obstet Gynecol , vol.186 , pp. 717-722
    • Lundstrom, E.1    Christow, A.2    Kersemaekers, W.3
  • 37
    • 0036188092 scopus 로고    scopus 로고
    • Mammographic changes associated with raloxifene and tibolone therapy in postmenopausal women: A prospective study
    • Christodoulakos GE, Lambrinoudaki IV, Vourtsi AD, et al. Mammographic changes associated with raloxifene and tibolone therapy in postmenopausal women: a prospective study. Menopause 2002;9:110-16.
    • (2002) Menopause , vol.9 , pp. 110-116
    • Christodoulakos, G.E.1    Lambrinoudaki, I.V.2    Vourtsi, A.D.3
  • 38
    • 0038173308 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on mammographic findings
    • Bulbul NH, Ozden S, Dayicioglu V. Effects of hormone replacement therapy on mammographic findings. Arch Gynecol Obstet 2003;268:5-8.
    • (2003) Arch Gynecol Obstet , vol.268 , pp. 5-8
    • Bulbul, N.H.1    Ozden, S.2    Dayicioglu, V.3
  • 39
    • 7944229473 scopus 로고    scopus 로고
    • Long-term effects of tibolone on mammographic density
    • Bruce D, Robinson J, McWilliams S, et al. Long-term effects of tibolone on mammographic density. Fertil Steril 2004;82:1343-7.
    • (2004) Fertil Steril , vol.82 , pp. 1343-1347
    • Bruce, D.1    Robinson, J.2    McWilliams, S.3
  • 40
    • 28444479849 scopus 로고    scopus 로고
    • Postmenopausal hormone therapy and mammographic breast density
    • Marcnesoni D, Driul L, lanni A, et al. Postmenopausal hormone therapy and mammographic breast density. Maturitas 2006;53:59-64.
    • (2006) Maturitas , vol.53 , pp. 59-64
    • Marcnesoni, D.1    Driul, L.2    Lanni, A.3
  • 41
    • 0038131731 scopus 로고    scopus 로고
    • Hormone replacement therapy in postmenopausal women with benign fibrocystic mastopathy
    • Yenen MC, Dede M, Goktolga U, et al. Hormone replacement therapy in postmenopausal women with benign fibrocystic mastopathy. Climacteric 2003;6:146-50.
    • (2003) Climacteric , vol.6 , pp. 146-150
    • Yenen, M.C.1    Dede, M.2    Goktolga, U.3
  • 42
    • 0042018741 scopus 로고    scopus 로고
    • Breast cancer and hormone-replacement therapy in the Million Women Study
    • Million Women Study Collaborators
    • Million Women Study Collaborators Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 2003;362:419-27.
    • (2003) Lancet , vol.362 , pp. 419-427
  • 43
    • 3242665917 scopus 로고    scopus 로고
    • Clinical background of women prescribed tibolone or combined estrogen + progestogen therapies: A UK MediPlus study
    • Wierik EJ, Hendricks PT, Boerstoel-Streefland M. Clinical background of women prescribed tibolone or combined estrogen + progestogen therapies: a UK MediPlus study. Climacteric 2004;7:197-209.
    • (2004) Climacteric , vol.7 , pp. 197-209
    • Wierik, E.J.1    Hendricks, P.T.2    Boerstoel-Streefland, M.3
  • 44
    • 1642419529 scopus 로고    scopus 로고
    • Increased risk of breast cancer following different regimens of normone replacement therapy frequently used in Europe
    • Stahlberg C, Pedersen AT, Lynge E, et al. Increased risk of breast cancer following different regimens of normone replacement therapy frequently used in Europe. Int J Cancer 2004;109:721-7.
    • (2004) Int J Cancer , vol.109 , pp. 721-727
    • Stahlberg, C.1    Pedersen, A.T.2    Lynge, E.3
  • 45
    • 13244269907 scopus 로고    scopus 로고
    • The effect of tibolone in postmenopausal women receiving tamoxifen after surgery for breast cancer: A randomised, double-blind, placeoo-controlled trial
    • Kroiss R, Fentiman IS, Helmond FA, et al. The effect of tibolone in postmenopausal women receiving tamoxifen after surgery for breast cancer: a randomised, double-blind, placeoo-controlled trial. BJOG 2005;112:228-33.
    • (2005) BJOG , vol.112 , pp. 228-233
    • Kroiss, R.1    Fentiman, I.S.2    Helmond, F.A.3
  • 46
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative Randomized Controlled Trial
    • Writing Group for the WHI Investigators
    • Writing Group for the WHI Investigators Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative Randomized Controlled Trial. JAMA 2002;288:321-33.
    • (2002) JAMA , vol.288 , pp. 321-333


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.