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Volumn 17, Issue 1 A, 1997, Pages 135-140

Effect of Tibolone (Org OD14) and its metabolites on estrone sulphatase activity in MCF-7 and T-47D mammary cancer cells

Author keywords

19 nortestosterone derivatives; Estrone sulphatase; Mammary cancer cells

Indexed keywords

DRUG METABOLITE; ESTRADIOL; ESTRONE SULFATE; NORETHISTERONE; ORG 30126; ORG 4094; ORG OM38; SULFATASE; TIBOLONE; UNCLASSIFIED DRUG;

EID: 0031050931     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (124)

References (35)
  • 2
    • 0018915706 scopus 로고
    • Cancer of the breast: The last decade
    • Henderson IC and Cannellos GP: Cancer of the breast: the last decade. New Engl J Med 302: 17-30, 1980.
    • (1980) New Engl J Med , vol.302 , pp. 17-30
    • Henderson, I.C.1    Cannellos, G.P.2
  • 3
    • 0016148167 scopus 로고
    • Steroid sulfatase activities in human breast tumors
    • Dao TL, Haves C and Libby PR: Steroid sulfatase activities in human breast tumors. Proc Soc Expl Biol Med 146: 381-384, 1974.
    • (1974) Proc Soc Expl Biol Med , vol.146 , pp. 381-384
    • Dao, T.L.1    Haves, C.2    Libby, P.R.3
  • 4
    • 0021020861 scopus 로고
    • Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma
    • Tseng L, Mazella J, Lee LY and Stone ML: Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma. J Steroid Biochem 19: 1413-1417, 1983.
    • (1983) J Steroid Biochem , vol.19 , pp. 1413-1417
    • Tseng, L.1    Mazella, J.2    Lee, L.Y.3    Stone, M.L.4
  • 6
    • 0022905804 scopus 로고
    • Biological effects and morphological responses to estriol, estriol-3-sulfate, estriol-17-sulfate and tamoxifen in a tamoxifen-resistant cell line (R-27) derived from MCF-7 human breast cancer cells
    • Pasqualini JR, Gelly C and Lecerf F: Biological effects and morphological responses to estriol, estriol-3-sulfate, estriol-17-sulfate and tamoxifen in a tamoxifen-resistant cell line (R-27) derived from MCF-7 human breast cancer cells. Eur J Cancer Clin Oncol 22: 1495- 1501, 1986.
    • (1986) Eur J Cancer Clin Oncol , vol.22 , pp. 1495-1501
    • Pasqualini, J.R.1    Gelly, C.2    Lecerf, F.3
  • 8
    • 0026609036 scopus 로고
    • Recent data on estrogen sulfatases and sulfotransferases activities in human breast cancer
    • Pasqualini JR, Schatz B, Varin C and Nguyen B-L: Recent data on estrogen sulfatases and sulfotransferases activities in human breast cancer. J Steroid Biochem Molec Biol 41: 323-329, 1992.
    • (1992) J Steroid Biochem Molec Biol , vol.41 , pp. 323-329
    • Pasqualini, J.R.1    Schatz, B.2    Varin, C.3    Nguyen, B.-L.4
  • 9
    • 0018893170 scopus 로고
    • The conversion of androstenedione to estrone, estradiol, and testosterone in breast tissue
    • Perel E, Wilkins D and Killinger DW: The conversion of androstenedione to estrone, estradiol, and testosterone in breast tissue. J Steroid Biochem 13: 89-94, 1980.
    • (1980) J Steroid Biochem , vol.13 , pp. 89-94
    • Perel, E.1    Wilkins, D.2    Killinger, D.W.3
  • 11
    • 0018509037 scopus 로고
    • Relationship between estrogen receptors, 17β- Hydroxysteroid dehydrogenase and estrogen content in human breast cancer
    • Abul-Hajj YJ: Relationship between estrogen receptors, 17β- hydroxysteroid dehydrogenase and estrogen content in human breast cancer. Steroids 34: 217-225, 1979.
    • (1979) Steroids , vol.34 , pp. 217-225
    • Abul-Hajj, Y.J.1
  • 12
    • 0022642042 scopus 로고
    • Aromatase, 17β-hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal glandular breast tissue in postmenopausal women
    • Vermeulen A, Deslypere JP, Paridaens R, Leclercq G, Roy F and Heuson JC: Aromatase, 17β-hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal glandular breast tissue in postmenopausal women. Eur J Cancer Clin Oncol 22: 515-525, 1986.
    • (1986) Eur J Cancer Clin Oncol , vol.22 , pp. 515-525
    • Vermeulen, A.1    Deslypere, J.P.2    Paridaens, R.3    Leclercq, G.4    Roy, F.5    Heuson, J.C.6
  • 13
    • 0021149871 scopus 로고
    • In situ estrogen production via the estrone sulfatase pathway in breast tumors: Relative importance versus the aromatase pathway
    • Santner SJ, Feil PD and Santen RJ: In situ estrogen production via the estrone sulfatase pathway in breast tumors: relative importance versus the aromatase pathway. J Clin Endocr Metab 59: 29-33, 1984.
    • (1984) J Clin Endocr Metab , vol.59 , pp. 29-33
    • Santner, S.J.1    Feil, P.D.2    Santen, R.J.3
  • 14
    • 0029872530 scopus 로고    scopus 로고
    • Concentration of estrone, estradiol, estrone sulfate, and evaluation of sulfatase and aromatase activities in pre- And postmenopausal breast cancer patients
    • Pasqualini JR, Chetrite G, Blacker C, Feinstein M-C, Delalonde L, Talbi M and Maloche C: Concentration of estrone, estradiol, estrone sulfate, and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients. J Clin Endocr Metab 81: 1460-1464, 1996.
    • (1996) J Clin Endocr Metab , vol.81 , pp. 1460-1464
    • Pasqualini, J.R.1    Chetrite, G.2    Blacker, C.3    Feinstein, M.-C.4    Delalonde, L.5    Talbi, M.6    Maloche, C.7
  • 15
    • 0025371743 scopus 로고
    • Biological response of the antiestrogen ICI 164,384 in human hormone-dependent and hormone-independent mammary cancer cell lines
    • Pasqualini JR and Gelly C: Biological response of the antiestrogen ICI 164,384 in human hormone-dependent and hormone-independent mammary cancer cell lines. Cancer Lett 50: 133-139, 1990.
    • (1990) Cancer Lett , vol.50 , pp. 133-139
    • Pasqualini, J.R.1    Gelly, C.2
  • 16
    • 0025922892 scopus 로고
    • Estrone sulfatase activity and effect of antiestrogens on transformation of estrone sulfate in hormone- Dependent vs. -independent human breast cancer cell lines
    • Pasqualini JR and Nguyen B-L: Estrone sulfatase activity and effect of antiestrogens on transformation of estrone sulfate in hormone- dependent vs. -independent human breast cancer cell lines. Breast Cancer Res Treat 18: 93-98, 1991.
    • (1991) Breast Cancer Res Treat , vol.18 , pp. 93-98
    • Pasqualini, J.R.1    Nguyen, B.-L.2
  • 17
    • 0026697677 scopus 로고
    • Effect of the progestagen R5020 (Promegestone) and of progesterone on the uptake and on the transformation of estrone sulfate in the MCF-7 and T-47D human mammary cancer cells. Correlation with progesterone receptor levels
    • Pasqualini JR, Varin C and Nguyen B-L: Effect of the progestagen R5020 (Promegestone) and of progesterone on the uptake and on the transformation of estrone sulfate in the MCF-7 and T-47D human mammary cancer cells. Correlation with progesterone receptor levels. Cancer Lett 66: 55-60, 1992.
    • (1992) Cancer Lett , vol.66 , pp. 55-60
    • Pasqualini, J.R.1    Varin, C.2    Nguyen, B.-L.3
  • 18
    • 0027183776 scopus 로고
    • Action of Danazol on the conversion of estrone sulfate to estradiol and on the sulfatase activity in the MCF-7, T-47D and MDA-MB-231 human mammary cancer cells
    • Nguyen B-L, Ferme I, Chetrite G and Pasqualini JR: Action of Danazol on the conversion of estrone sulfate to estradiol and on the sulfatase activity in the MCF-7, T-47D and MDA-MB-231 human mammary cancer cells. J Steroid Biochem Molec Biol 46: 17-23, 1993.
    • (1993) J Steroid Biochem Molec Biol , vol.46 , pp. 17-23
    • Nguyen, B.-L.1    Ferme, I.2    Chetrite, G.3    Pasqualini, J.R.4
  • 19
    • 0021234396 scopus 로고
    • Endocrinal studies with (7α,17α)-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one (Org OD14)
    • Visser de J, Coert A Feenstra H and Vies van der J: Endocrinal studies with (7α,17α)-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one (Org OD14). Arzneim Forsch Drug Res 34: 1010-1017, 1984.
    • (1984) Arzneim Forsch Drug Res , vol.34 , pp. 1010-1017
    • De Visser, J.1    Coert, A.2    Feenstra, H.3    Vies van der, J.4
  • 20
    • 0003969618 scopus 로고
    • Pharmacological profile of Org OD 14 in experimental animals
    • Proceedings of a Symposium held at the 6th International Congress on the Menopause (Bangkok, October 1990). The Parthenon Publishing Group. Carnforth, England
    • Schot LPC, Kloosterboer HJ and Deckers GHJ: Pharmacological profile of Org OD 14 in experimental animals. In: Livial - The Current Status of Research and Therapy. Proceedings of a Symposium held at the 6th International Congress on the Menopause (Bangkok, October 1990). The Parthenon Publishing Group. Carnforth, England, 1992, pp 11-24.
    • (1992) Livial - the Current Status of Research and Therapy , pp. 11-24
    • Schot, L.P.C.1    Kloosterboer, H.J.2    Deckers, G.H.J.3
  • 21
    • 0023078397 scopus 로고
    • Clinical profile of Org OD14
    • Tax L, Goorissen EM and Kicovic PM: Clinical profile of Org OD14. Maturitas I (suppl.): 3-13, 1987.
    • (1987) Maturitas , vol.1 , Issue.SUPPL. , pp. 3-13
    • Tax, L.1    Goorissen, E.M.2    Kicovic, P.M.3
  • 22
    • 0023072302 scopus 로고
    • Use of Org OD 14 for the treament of climacteric complaints
    • Aloysio de D, Fabiani AG, Mauloni M and Bottiglioni F: Use of Org OD 14 for the treament of climacteric complaints. Maturitas (suppl.): 49-65, 1987.
    • (1987) Maturitas , Issue.SUPPL. , pp. 49-65
    • De Aloysio, D.1    Fabiani, A.G.2    Mauloni, M.3    Bottiglioni, F.4
  • 23
    • 0027216228 scopus 로고
    • Human endometrial 3β-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic / progestagenic activity ratios of a steroidal drug (Org OD 14)
    • Tang B, Markiewicz L, Kloosterboer HJ and Gurpide E: Human endometrial 3β-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic / progestagenic activity ratios of a steroidal drug (Org OD 14). J Steroid Biochem Molec Biol 45: 345-351, 1993.
    • (1993) J Steroid Biochem Molec Biol , vol.45 , pp. 345-351
    • Tang, B.1    Markiewicz, L.2    Kloosterboer, H.J.3    Gurpide, E.4
  • 24
    • 0025359604 scopus 로고
    • In vitro evaluation of estrogenic, estrogen antagonistic and progestagenic effects of a steroidal drug (Org OD14) and its metabolites on human endometrium
    • Markiewicz L and Gurpide E: In vitro evaluation of estrogenic, estrogen antagonistic and progestagenic effects of a steroidal drug (Org OD14) and its metabolites on human endometrium. J Steroid Biochem Molec Biol 35: 535-541, 1990.
    • (1990) J Steroid Biochem Molec Biol , vol.35 , pp. 535-541
    • Markiewicz, L.1    Gurpide, E.2
  • 25
    • 0028060122 scopus 로고
    • Progestogen use and decreased risk of breast cancer in a cohort study of premenopausal women with benign breast disease
    • Plu-Bureau G, Lê MG, Sitruk-Ware R, Thalabard JC and Mauvais-Jarvis P: Progestogen use and decreased risk of breast cancer in a cohort study of premenopausal women with benign breast disease. Br J Cancer 70: 270-277, 1994.
    • (1994) Br J Cancer , vol.70 , pp. 270-277
    • Plu-Bureau, G.1    Lê, M.G.2    Sitruk-Ware, R.3    Thalabard, J.C.4    Mauvais-Jarvis, P.5
  • 26
    • 0029999704 scopus 로고    scopus 로고
    • Hormone replacement therapy and breast cancer: An overview
    • Theriault RL: Hormone replacement therapy and breast cancer: an overview. Br J Obstet Gynaecol 103 (Suppl 13): 87-91, 1996.
    • (1996) Br J Obstet Gynaecol , vol.103 , Issue.SUPPL. 13 , pp. 87-91
    • Theriault, R.L.1
  • 28
    • 6544229829 scopus 로고
    • A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid
    • Burton K: A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J 62: 315-323, 1956.
    • (1956) Biochem J , vol.62 , pp. 315-323
    • Burton, K.1
  • 30
    • 0028212467 scopus 로고
    • Estrogenic and progestagenic activities coexisting in steroidal drugs: Quantitative evaluation by in vitro bioassays with human cells
    • Markiewicz L and Gurpide E: Estrogenic and progestagenic activities coexisting in steroidal drugs: Quantitative evaluation by in vitro bioassays with human cells. J Steroid Biochem Molec Biol 48: 89-94, 1994.
    • (1994) J Steroid Biochem Molec Biol , vol.48 , pp. 89-94
    • Markiewicz, L.1    Gurpide, E.2
  • 32
    • 0026483203 scopus 로고
    • Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation
    • Jeng MH, Parker CJ and Jordan VC: Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation. Cancer Res 52: 6539-6546, 1992.
    • (1992) Cancer Res , vol.52 , pp. 6539-6546
    • Jeng, M.H.1    Parker, C.J.2    Jordan, V.C.3
  • 33
    • 0030000556 scopus 로고    scopus 로고
    • Tibolone versus conjugated estrogens and sequential progestogen in the treatment of climacteric complaints
    • Egarter C, Huber J, Leikermoser R, Haidbauer R, Pusch H, Fischl F and Putz M: Tibolone versus conjugated estrogens and sequential progestogen in the treatment of climacteric complaints. Maturitas 23: 55-62, 1996.
    • (1996) Maturitas , vol.23 , pp. 55-62
    • Egarter, C.1    Huber, J.2    Leikermoser, R.3    Haidbauer, R.4    Pusch, H.5    Fischl, F.6    Putz, M.7
  • 34
    • 0029417037 scopus 로고
    • Effects of two classes of progestagens. pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: I. MCF-7 cell lines
    • Schoonen WGEJ, Joosten JWH and Kloosterboer HJ: Effects of two classes of progestagens. pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: I. MCF-7 cell lines. J Steroid Biochem Molec Biol 55: 423-437, 1995.
    • (1995) J Steroid Biochem Molec Biol , vol.55 , pp. 423-437
    • Schoonen, W.G.E.J.1    Joosten, J.W.H.2    Kloosterboer, H.J.3
  • 35
    • 0029586264 scopus 로고
    • Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines
    • Schoonen WGEJ, Joosten JWH and Kloosterboer HJ: Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines. J Steroid Biochem Molec Biol 55: 439-444, 1995.
    • (1995) J Steroid Biochem Molec Biol , vol.55 , pp. 439-444
    • Schoonen, W.G.E.J.1    Joosten, J.W.H.2    Kloosterboer, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.