The monosialosyl ganglioside GM-1 reduces the vagolytic efficacy of δ2-opioid receptor stimulation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 291, Issue 5, 2006, Pages

  Davis, Shavsha ^a   Deo, Shekhar H ^a   Barlow, Matthew ^a   Yoshishige, Darice ^a   Farias, Martin ^a   Caffrey, James L ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Bradycardia; Deltorphin; Heart rate

Indexed keywords

7 BENZYLIDENALTREXONE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR ANTAGONIST; DELTORPHIN; GANGLIOSIDE GM1; METENKEPHALIN[6 ARGININE 7 PHENYLALANINE]; OPIOID RECEPTOR DELTA1; OPIOID RECEPTOR DELTA2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEART RATE; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REST; STIMULATION; VAGUS NERVE; VAGUS TONE;

ANALGESICS, OPIOID; ANIMALS; BENZYLIDENE COMPOUNDS; BRADYCARDIA; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, METHIONINE; FEMALE; G(M1) GANGLIOSIDE; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; OLIGOPEPTIDES; RECEPTORS, OPIOID, DELTA; SINOATRIAL NODE; STIMULATION, CHEMICAL; VAGUS NERVE;

EID: 33751200487     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00455.2006     Document Type: Article

References (31)

1. Allouche S, Hasbi A, Ferey V, Sola B, Jauzak P, and Polastron J. Pharmacological δ-1 and δ-2 opioid receptor subtypes in the human neuroblastoma cell line SK-N-BE: no evidence for distinct molecular entities. Biochem Pharmacol 59: 915-925, 2000.
2. Barron BA, Oakford LX, Gaugl JF, and Caffrey JL. Methionine-enkephalin- arg-phe immunoreactivity in heart tissue. Peptides 16: 1221-1227, 1995.
3. Caffrey JL. Enkephalin inhibits vagal control of heart rate, contractile force, and coronary blood flow in the canine heart in vivo. J Auton Nerv Syst 76: 75-82, 1999.
4. Crain SM and Shen KF. Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons. Trends Pharmacol Sci 11: 77-81, 1990.
5. Crain SM and Shen KF. After chronic opioid exposure to sensory neurons become supersensitive to the excitatory effects of opioid agonists and antagonists as occurs after acute elevation of GM-1 ganglioside. Brain Res 575: 13-24, 1992.
6. Cruciani RA, Dvorkin B, Morris SA, Crain SM, and Makman MH. Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells. Proc Natl Acad Sci USA 90: 3019-3023, 1993.
7. 2-opioid receptor responses in the SA node. Am J Physiol Heart Circ Physiol 291: H2246-H2254, 2006.
8. Evans CJ, Keith DE, Morrison H, Magendzo K, and Edwards RH. Cloning of a δ-opioid receptor by functional expression. Science 258: 1952-1955, 1992.
9. Farias M, Jackson K, Stanfill A, and Caffrey JL. Local opiate receptors in the sinoatrial node moderate vagal, bradycardia. Auto Neurosci (Basic and Clin) 87:9-15, 2001.
10. Farias M, Jackson K, Johnson M, and Caffrey JL. Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node. Am J Physiol Heart Circ Physiol 285: H2001-H2012, 2003.
11. Farias M, Jackson K, Yoshishige D, and Caffrey JL. Bimodal δ-opioid receptors regulate vagal bradycardia in canine sinoatrial node. Am J Physiol Heart Circ Physiol 285: H1332-H1339, 2003.
12. Howells RD, Kilpatrick DL, Bailey LC, Noe M, and Udenfriend S. Proenkephalin mRNA in rat heart. Proc Natl Acad Sci USA 83: 1960-1963, 1986.
13. Jackson KE, Farias M, Stanfill A, and Caffrey JL. Delta opioid receptors inhibit vagal bradycardia in the sinoatrial node. J Cardiovasc Pharmacol Ther 6: 385-393, 2001.
14. James TN. Structure and function of the sinus node, AV node and his bundle of the human heart. II. Function. Prog Cardiovasc Dis 45: 327-360, 2003.
15. Jin ZQ, Zhou HZ, Zhu P, Honbo N, Mochly-Rosen D, Messing RO, Goetzl EJ, Karliner JS, and Gray MO. Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts. Am J Physiol Heart Circ Physiol 282: H1970-H1977, 2002.
16. Karliner JS, Honbo N, Summers K, Gray MO, and Goetzl EJ. The lysophospholipids sphingosine-1-phosphate and lysophosphotidic acid enhance survival during hypoxia in neonatal rat cardiomyocytes. J Mol Cell Cardiol 33: 1713-1717, 2001.
17. Kleiger RE, Miller JP, and Bigger JT Jr, and Moss AJ. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 59: 256-262, 1987.
18. Kieffer BL, Befort K, Gaveriaux-Ruff C, and Hirth CG. The opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc Natl Acad Sci USA 89: 12048-12052, 1992.
19. Lang RE, Hermann K, Dietz R, Gaida W, Ganten D, Kraft K, and Unger T. Evidence for the presence of enkephalins in the heart. Life Sci 32: 399-406, 1983.
20. Martin WR. Pharmacology of opioids. Pharmacol Rev 35: 285-323, 1984.
21. Portoghese PS, Sultana M, Nagase H, and Takemori AE. A highly selective δ-1 receptor antagonist: 7-benzylidenaltrexone. Eur J Pharmacol 218: 195-196, 1992.
22. Sarne Y, Fields A, Keren O, and Gafni M. Stimulatory effects of opioids on transmitter release and possible cellular mechanisms: overview and original results. Neurochem Res 21:1353-1361, 1996.
23. Saul JP. Beat-to-beat variations of heart rate reflect modulation of cardiac autonomic outflow. News Physiol Sci 5: 32-37, 1990.
24. Shen KF and Crain SM. Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture. Brain Res 491: 227-242, 1989.
25. Sofuoglu M, Portoghese PS, and Takemori AE. Differential antagonism of δ-opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: evidence for δ-opioid receptor subtypes. J Pharmacol Exp Ther 257: 676-680, 1991.
26. Somers VK and Abboud FM. Baroreflexes in health and disease. In: Vagal Control of the Heart, edited by Levy ML and Schwartz PJ. Armonk, NY: Futura, 1994, p. 381-401.
27. Stanfill A, Jackson K, Farias M, Barlow M, Deo S, Johnson S, and Caffrey JL. Leucine-enkepahlin interrupts sympathetically mediated tachycardia prejunctionally in the canine sinoatrial node. Exp Biol Med 228: 898-906, 2003.
28. Wu G, Lu ZH, and Ledeen RW. Interaction of δ-opioid receptors with GM-1 ganglioside: conversion of inhibitory to excitatory mode. Mol Brain Res 44: 341-346, 1997.
29. Younes A, Pepe S, Barron B, Surgeon H, Lakatta E, and Caffrey J. Cardiac synthesis, processing, and coronary release of enkephalin-related peptides. Am J Physiol Heart Circ Physiol 279: H1989-H1998, 2000.
30. Varga EV, Navratilova E, Stropova D, Jambrosic J, Roeske WR, and Yamamura HI. Agonist-specific regulation of the delta-opioid receptor. Life Sci 76: 599-612, 2004.
31. Zaki PA, Bilsky EJ, Evans CJ, and Porreca F. Opioid receptor types and subtypes: the δ-receptor as a model. Annu Rev Pharmacol Toxicol 36: 379-401, 1996.