Concurrent chemo-radiation in the conservative management of breast cancer

International Journal of Radiation Oncology Biology Physics

Volumn 66, Issue 5, 2006, Pages 1306-1312

  Haffty, Bruce G ^a   Kim, Janet H ^b   Yang, Qifeng ^a   Higgins, Susan A ^b  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; Chemotherapy; Concurrent; Radiation therapy; Sequencing

Indexed keywords

CHEMOTHERAPY; MULTIVARIABLE SYSTEMS; RADIOTHERAPY; RISK MANAGEMENT; TOXICITY;

BREAST CANCER; CONCURRENT RADIOTHERAPY; RETROSPECTIVE ANALYSIS; SEQUENCING;

ONCOLOGY;

CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; METHOTREXATE; PACLITAXEL; PREDNISOLONE; VINCRISTINE;

ADULT; ARTICLE; BLOOD TOXICITY; BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CANCER CONTROL; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL ARTICLE; COMPARATIVE STUDY; CONSERVATIVE TREATMENT; CONTROLLED STUDY; DISEASE FREE INTERVAL; FEMALE; FOLLOW UP; HUMAN; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RADIATION PNEUMONIA; RETROSPECTIVE STUDY; SAMPLE SIZE; SKIN TOXICITY; SURVIVAL RATE; SURVIVAL TIME; TREATMENT OUTCOME;

ADULT; BREAST NEOPLASMS; COMBINED MODALITY THERAPY; FEMALE; HUMANS; MIDDLE AGED; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 33751180998     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.03.022     Document Type: Article

References (38)

1. National Institutes of Health Consensus Development Conference Statement: Adjuvant therapy for breast cancer, November 1-3, 2000. J Natl Cancer Inst Monogr 2001 (2001) 5-15
2. Fisher B., Anderson S., Bryant J., et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 347 (2002) 1233-1241
3. Veronesi U., Cascinelli N., Mariani L., et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med 347 (2002) 1227-1232
4. Buchholz T.A., Hunt K.K., Amosson C.M., et al. Sequencing of chemotherapy and radiation in lymph node-negative breast cancer. Cancer J Sci Am 5 (1999) 159-164
5. Buchholz T.A., Tucker S.L., Erwin J., et al. Impact of systemic treatment on local control for patients with lymph node-negative breast cancer treated with breast-conservation therapy. J Clin Oncol 19 (2001) 2240-2246
6. Hartsell W.F., Recine D.C., Griem K.L., et al. Delaying the initiation of intact breast irradiation for patients with lymph node positive breast cancer increases the risk of local recurrence. Cancer 76 (1995) 2497-2503
7. Huang J., Barbera L., Brouwers M., et al. Does delay in starting treatment affect the outcomes of radiotherapy?. A systematic review. J Clin Oncol 21 (2003) 555-563
8. Recht A., Come S.E., Gelman R.S., et al. Integration of conservative surgery, radiotherapy, and chemotherapy for the treatment of early-stage, node-positive breast cancer: Sequencing, timing, and outcome. J Clin Oncol 9 (1991) 1662-1667
9. Bellon J.R., Come S.E., Gelman R.S., et al. Sequencing of chemotherapy and radiation therapy in early-stage breast cancer: updated results of a prospective randomized trial. J Clin Oncol 23 (2005) 1934-1940
10. Recht A., Come S.E., Henderson I.C., et al. The sequencing of chemotherapy and radiation therapy after conservative surgery for early-stage breast cancer. N Engl J Med 334 (1996) 1356-1361
11. Sartor C.I., Peterson B.L., Woolf S., et al. Effect of addition of adjuvant paclitaxel on radiotherapy delivery and locoregional control of node-positive breast cancer: Cancer and leukemia group B 9344. J Clin Oncol 23 (2005) 30-40
12. Lingos T.I., Recht A., Vicini F., et al. Radiation pneumonitis in breast cancer patients treated with conservative surgery and radiation therapy. Int J Radiat Oncol Biol Phys 21 (1991) 355-360
13. Recht A. Integration of systemic therapy and radiation therapy for patients with early-stage breast cancer treated with conservative surgery. Clin Breast Cancer 4 (2003) 104-113
14. Bellon J.R., and Harris J.R. Chemotherapy and radiation therapy for breast cancer: What is the optimal sequence?. J Clin Oncol 23 (2005) 5-7
15. Bellon J.R., Shulman L.N., Come S.E., et al. A prospective study of concurrent cyclophosphamide/methotrexate/5-fluorouracil and reduced-dose radiotherapy in patients with early-stage breast carcinoma. Cancer 100 (2004) 1358-1364
16. Lamb D., Atkinson C., Joseph D., et al. Simultaneous adjuvant radiotherapy and chemotherapy for stage I and II breast cancer. Australas Radiol 43 (1999) 220-226
17. Markiewicz D.A., Fox K.R., Schultz D.J., et al. Concurrent chemotherapy and radiation for breast conservation treatment of early-stage breast cancer. Cancer J Sci Am 4 (1998) 185-193
18. Jobsen J.J., van der Palen J., Ong F., et al. The value of a positive margin for invasive carcinoma in breast-conservative treatment in relation to local recurrence is limited to young women only. Int J Radiat Oncol Biol Phys 57 (2003) 724-731
19. Obedian E., and Haffty B.G. Negative margin status improves local control in conservatively managed breast cancer patients. Cancer J Sci Am 6 (2000) 28-33
20. Park C.C., Mitsumori M., Nixon A., et al. Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: Influence of margin status and systemic therapy on local recurrence. J Clin Oncol 18 (2000) 1668-1675
21. Schnitt S.J., Abner A., Gelman R., et al. The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast-conserving surgery and radiation therapy. Cancer 74 (1994) 1746-1751
22. Smitt M.C., Nowels K.W., Zdeblick M.J., et al. The importance of the lumpectomy surgical margin status in long-term results of breast conservation. Cancer 76 (1995) 259-267
23. Vicini F.A., Kestin L.L., Goldstein N.S., et al. Relationship between excision volume, margin status, and tumor size with the development of local recurrence in patients with ductal carcinoma-in-situ treated with breast-conserving therapy. J Surg Oncol 76 (2001) 245-254
24. Vicini F.A., Kestin L.L., Goldstein N.S., et al. Impact of young age on outcome in patients with ductal carcinoma-in-situ treated with breast-conserving therapy. J Clin Oncol 18 (2000) 296-306
25. Haffty B.G., Fischer D., and Fischer J.J. Regional nodal irradiation in the conservative treatment of breast cancer. Int J Radiat Oncol Biol Phys 19 (1990) 859-865
26. Norton L. Adjuvant breast cancer therapy: Current status and future strategies-growth kinetics and the improved drug therapy of breast cancer. Semin Oncol 26 (1999) 1-4
27. Buchholz T.A., Austin-Seymour M.M., Moe R.E., et al. Effect of delay in radiation in the combined modality treatment of breast cancer. Int J Radiat Oncol Biol Phys 26 (1993) 23-35
28. Recht A., Harris J.R., and Come S.E. Sequencing of irradiation and chemotherapy for early-stage breast cancer. Oncology (Huntingt) 2 (1994) 19-37
29. Haffty B.G. Who's on first?. Sequencing chemotherapy and radiation therapy in conservatively managed node-negative breast cancer. Cancer J Sci Am 5 (1999) 147-149
30. Burstein H.J., Bellon J.R., Galper S., et al. Prospective evaluation of concurrent paclitaxel and radiation therapy after adjuvant doxorubicin and cyclophosphamide chemotherapy for Stage II or III breast cancer. Int J Radiat Oncol Biol Phys 64 (2006) 496-504
31. Calais G., Serin D., Fourquet A., et al. Randomized study comparing adjuvant radiotherapy with concomitant chemotherapy versus sequential treatment after conservative surgery for patients with stages I and II breast carcinoma: Long term results. [Abstract]. Int J Radiat Oncol Biol Phys 63 suppl. 1 (2005) S53
32. Rouesse J., de la Lande B., Bertheault-Cvitkovic F., et al. A phase III randomized trial comparing adjuvant concomitant chemoradiotherapy versus standard adjuvant chemotherapy followed by radiotherapy in operable node-positive breast cancer: Final results. Int J Radiat Oncol Biol Phys 64 (2006) 1072-1080
33. Violet J.A., and Harmer C. Breast cancer: Improving outcome following adjuvant radiotherapy. Br J Radiol 77 (2004) 811-820
34. Buchholz T.A., Tucker S.L., Masullo L., et al. Predictors of local-regional recurrence after neoadjuvant chemotherapy and mastectomy without radiation. J Clin Oncol 20 (2002) 17-23
35. Moran M.S., and Haffty B.G. Local-regional breast cancer recurrence: Prognostic groups based on patterns of failure. Breast J 8 (2002) 81-87
36. Rauschecker H., Clarke M., Gatzemeier W., et al. Systemic therapy for treating locoregional recurrence in women with breast cancer (Cochrane Review). Cochrane Database Syst Rev 4 (2001) CD002195
37. Recht A. Locoregional failure rates in patients with involved axillary nodes after mastectomy and systemic therapy. Semin Radiat Oncol 9 (1999) 223-229
38. Veronesi U., Marubini E., Del Vecchio M., et al. Local recurrences and distant metastases after conservative breast cancer treatments: Partly independent events. J Natl Cancer Inst 87 (1995) 19-27