Resistance training increases basal limb blood flow and vascular conductance in aging humans

Journal of Applied Physiology

Volumn 101, Issue 5, 2006, Pages 1351-1355

  Anton, Maria M ^a   Cortez Cooper, Miriam Y ^a   DeVan, Allison E ^a   Neidre, Daria B ^a   Cook, Jill N ^a   Tanaka, Hirofumi ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Hemodynamics; Strength exercise; Ultrasonics; Vascular resistance

Indexed keywords

ANGIOTENSIN II; ENDOTHELIN 1;

ADULT; AGING; ARTERY DIAMETER; ARTICLE; BLOOD PRESSURE; BODY FAT; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; FEMALE; FEMORAL ARTERY FLOW; HEART OUTPUT; HUMAN; HUMAN EXPERIMENT; LEAN BODY WEIGHT; LIMB BLOOD FLOW; MALE; MUSCLE STRETCHING; MUSCLE TRAINING; NORMAL HUMAN; PRIORITY JOURNAL; TRAINING; VASCULAR RESISTANCE;

AGING; BLOOD FLOW VELOCITY; BLOOD PRESSURE; EXERCISE; FEMALE; FEMORAL ARTERY; HUMANS; LEG; MALE; MIDDLE AGED; MUSCLE STRENGTH; PHYSICAL EDUCATION AND TRAINING; REGIONAL BLOOD FLOW; VASCULAR RESISTANCE; WEIGHT LIFTING;

EID: 33751166575     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00497.2006     Document Type: Article

References (27)

1. Baron AD, Laakso M, Brechtel G, Hoit B, Watt C, and Edelman SV. Reduced postprandial skeletal muscle blood flow contributes to glucose intolerance in human obesity. J Clin Endocrinol Metab 70: 1525-1533, 1990.
2. Dinenno FA, Jones PP, Seals DR, and Tanaka H. Limb blood flow and vascular conductance are reduced with age in healthy humans: relation to elevations in sympathetic nerve activity and declines in oxygen demand. Circulation 100: 164-170, 1999.
3. Dinenno FA, Tanaka H, Stauffer BL, and Seals DR. Reductions in basal limb blood flow and vascular conductance with human ageing: role for augmented alpha-adrenergic vasoconstriction. J Physiol 536: 977-983, 2001.
4. Dinenno FA, Seals DR, DeSouza CA, and Tanaka H. Age-related decreases in basal limb blood flow in humans: time course, determinants and habitual exercise effects. J Physiol 531: 573-579, 2001.
5. Frontera WR, Meredith CN, O'Reilly KP, Knuttgen HG, and Evans WJ. Strength conditioning in older men: skeletal muscle hypertrophy and improved function. J Appl Physiol 64: 1038-1044, 1988.
6. Frontera WR, Hughes VA, Krivickas LS, Kim SK, Foldvari M, and Roubenoff R. Strength training in older women: early and late changes in whole muscle and simple cells. Muscle Nerve 5: 601-608, 2003.
7. Hare DL, Ryan TM, Selig SE, Pellizzer A, Wringley TV, and Krum H. Resistance exercise training increases muscle strength, endurance, and blood flow in patients with chronic heart failure. Am J Cardiol 83: 1674-1677, 1999.
8. Hasten DL, Pak-Loduca J, Obert KA, and Yarasheski KE. Resistance exercise acutely increases MHC and mixed muscle protein synthesis rate in 78-84 and 23-32 yr olds. Am J Physiol Endocrinol Metab 278: E620-E626, 2000.
9. Kohrt WM. Aging and the osteogenic response to mechanical loading. Int J Sport Nutr Exerc Metab 11: S137-S142, 2001.
10. Lind L and Lithell H. Decreased peripheral blood flow in the pathogenesis of the metabolic syndrome comprising hypertension, hyperlipidemia, and hyperinsulinemia. Am Heart J 125: 1494-1497, 1993.
11. Martin JE, Dubbert PM, and Cushmam WC. Controlled trial of aerobic exercise in hypertension. Circulation 81: 1560-1567, 1990.
12. Mazzeo R, Cavanagh P, Evans WJ, Fiatarone M, Hagberg J, McAuley E, and Startzell J. ACSM position stand: exercise and physical activity for older adults. Med Sci Sports Exerc 30: 992-1008, 1998.
13. Miyachi M, Donato AJ, Yamamoto K, Takahashi K, Gates PE, Moreau KL, and Tanaka H. Greater age-related reductions in central arterial compliance in resistance-trained men. Hypertension 41: 130-135, 2003.
14. Miyachi M, Kawano H, Sugawara J, Takahashi K, Hayashi K, Yamazaki K, Tabata I, and Tanaka H. Unfavorable effects of resistance training on central arterial compliance: a randomized intervention study. Circulation 110: 2858-2863, 2004.
15. Miyachi M, Tanaka H, Kawano H, Okajima M, and Tabata I. Lack of age-related decreases in basal whole leg blood flow in resistance-trained men. J Appl Physiol 99: 1384-1390, 2005.
16. Moreau KL, Donato AJ, Tanaka H, Jones PP, Gates PE, and Seals DR. Basal leg blood flow in healthy women is related to age and hormone replacement therapy status. J Physiol 547: 309-316, 2003.
17. Muller-Delp J, Spier SA, Ramsey MW, Lesniewski LA, Papadopoulos A, Humphrey JD, and Delp MD. Effects of aging on vasoconstrictor and mechanical properties of rat skeletal muscle arterioles. Am J Physiol Heart Circ Physiol 282: H1843-H1854, 2002.
18. Partovian C, Zhuang Z, Moodie K, Lin M, Ouchi N, Sessa WC, Walsh K, and Simons M. PKCalpha activates eNOS and increases arterial blood flow in vivo. Circ Res 97: 482-487, 2005.
19. Pollock ML, Gaesser GA, Butcher JD, Després J, Dishman Rk Franklin BA, and Garber CE. The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc 30: 975-991, 1998.
20. Pollock ML, Franklin BA, Balady GJ, Chaitman BL, Fleg JL, Fletcher B, Limacher M, Pina IL, Stein RA, Williams M, and Bazzarre T. AHA science advisory. Resistance exercise in individuals with and without cardiovascular disease: benefits, rationale, safety, and prescription. Circulation 101: 828-833, 2000.
21. Pratley R, Nicklas B, Rubin M, Miller J, Smith A, Smith J, Hurley B, and Goldberg A. Strength training increases resting metabolic rate and norepinephrine levels in healthy 50- to 65-yr-old men. J Appl Physiol 76: 133-137, 1994.
22. Raastad T, Glomshller T, Bjoro T, and Hallen J. Changes in human skeletal muscle contractibility and hormone status during 2 weeks of heavy strength training. Eur J Appl Physiol 84: 54-63, 2001.
23. Rakobowchuk M, McGowan CL, de Groot PC, Hartman JW, Phillips SM, and MacDonald MJ. Endothelial function of young healthy males following whole body resistance training. J Appl Physiol 98: 2185-2190, 2005.
24. Ryan AS, Pratley RE, Elahi D, and Goldberg AP. Resistive training increases resting metabolic rate and norepinephrine levels in healthy 50- to 65-yr-old men. J Appl Physiol 76: 133-137, 1994.
25. Selig SE, Carey MF, Menzies DG, Patterson J, Geerling RH, Williams AD, Bamroongsuk V, Toia D, Krum H, and Hare DL. Moderate-intensity resistance exercise training in patients with chronic heart failure improves strength, endurance, heart rate variability, and forearm blood flow. J Card Fail 10: 21-30, 2004.
26. Tanaka H, Reiling MJ, and Seals DR. Regular walking increases peak limb vasodilatory capacity of older hypertensive humans: implications for arterial structure. J Hypertens 16: 423-428, 1998.
27. Tanaka H, Dinenno FA, Monahan KD, DeSouza CA, and Seals DR. Carotid artery wall hypertrophy with age is related to local systolic blood pressure in healthy men. Arterioscler Thromb Vasc Biol 21: 82-87, 2001.