Effects of trimethoprim on the clearance of apricitabine, a deoxycytidine analog reverse transcriptase inhibitor, and lamivudine in the isolated perfused rat kidney

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 2, 2006, Pages 941-947

  Nakatani Freshwater, Tomoko ^a   Babayeva, Mariana ^a   Dontabhaktuni, Aruna ^a   Taft, David R ^a  

^a LONG ISLAND UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 HYDROXYMETHYL[1,3]OXATHIOLAN 4 YL) 1H PYRIMIDINE 2,4 DIONE; APRICITABINE; BCH 335; CYTIDINE DERIVATIVE; DRUG METABOLITE; LAMIVUDINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TRIMETHOPRIM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLEARANCE; DRUG EFFECT; DRUG EXCRETION; DRUG INHIBITION; DRUG STRUCTURE; DRUG URINE LEVEL; GLOMERULUS FILTRATION RATE; IC 50; KIDNEY PERFUSION; KIDNEY TUBULE ABSORPTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; URINARY EXCRETION;

ANIMALS; ANTI-INFECTIVE AGENTS; DEOXYCYTIDINE; DRUG INTERACTIONS; KIDNEY; LAMIVUDINE; MALE; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE INHIBITORS; TRIMETHOPRIM;

EID: 33751164455     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.108522     Document Type: Article

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