Comparison of supercritical fluid chromatography and liquid chromatography for the separation of urinary metabolites of nobiletin with chiral and non-chiral stationary phases

Biomedical Chromatography

Volumn 20, Issue 11, 2006, Pages 1206-1215

  Wang, Zhenyu ^a   Li, Shiming ^a   Jonca, Malgorzata ^a   Lambros, Ted ^a   Ferguson, Stephen ^a   Goodnow, Robert ^a   Ho, Chi Tang ^b  

^a HOFFMANN LA ROCHE INC   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Chiral separation; Liquid chromatography; Metabolite; Nobiletin; Normal phase separation; Supercritical fluid chromatography

Indexed keywords

BIOMOLECULES; CHIRALITY; EFFLUENT TREATMENT; GAS CHROMATOGRAPHY; ISOMERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION; SUPERCRITICAL FLUIDS;

CHIRAL SEPARATIONS; CHIRAL STATIONARY PHASE; NOBILETIN; NORMAL PHASE; NORMAL PHASE SEPARATION; POLYMETHOXYLATED FLAVONE; SUPER CRITICAL FLUID CHROMATOGRAPHY; SUPERCRITICAL FLUID CHROMATOGRAPHY; SWEET ORANGE; URINARY METABOLITES;

METABOLITES;

3' NORMETHYLNOBILETIN; 4' NORMETHYLNOBILETIN; DRUG METABOLITE; NOBILETIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHIRAL CHROMATOGRAPHY; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; DRUG URINE LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; MOUSE; NONHUMAN; SUPERCRITICAL FLUID CHROMATOGRAPHY;

CITRUS SINENSIS;

EID: 33751094808     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.686     Document Type: Article

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