HL-60 differentiating activity and flavonoid content of the readily extractable fraction prepared from Citrus juices

Journal of Agricultural and Food Chemistry

Volumn 47, Issue 1, 1999, Pages 128-135

  Kawaii, Satoru ^a   Tomono, Yasuhiko ^a   Katase, Eriko ^a   Ogawa, Kazunori ^a   Yano, Masamichi ^a  

^a NATIONAL INSTITUTE OF FRUIT TREE SCIENCE   (Japan)

Author keywords

Citrus; Differentiation; Flavonoids; HL 60; HPLC; Multivariate analysis

Indexed keywords

ACETONE; ALCOHOL; AURANTIIN; BERGAMOT OIL; BIOFLAVONOID; CITRININ; FLAVONE DERIVATIVE; FLAVONOID; HESPERIDIN; NITROBLUE TETRAZOLIUM; NOBILETIN; PLANT EXTRACT; PLANT GLYCOSIDE; RESIN; TANGERETIN;

ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; CHEMISTRY; CITRUS FRUIT; CLUSTER ANALYSIS; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG SCREENING; FRUIT JUICE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PRINCIPAL COMPONENT ANALYSIS;

CELL DIFFERENTIATION; CITRUS; FLAVONOIDS; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PLANT EXTRACTS;

CITRUS; CITRUS NOBILIS;

EID: 0032933782     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf9805101     Document Type: Article

References (23)

1. Albach, R. F.; Redman, G. H. Composition and inheritance of flavanones in citrus fruit. Phytochemistry 1969, 8, 127-143.
2. Attaway, J. A. Citrus juice flavonoids with anticarcinogenic and antitumor properties. In Food Phytochemicals for Cancer Prevention I; Maple Press: York, PA, 1994; pp 240-248.
3. Benavente-García, O.; Castillo, J.; Marin, F. R.; Ortuño, A.; Del Río, J. A. Use and properties of Citrus flavonoids. J. Agric. Food Chem. 1997, 45, 4506-4515.
4. Chen, J.; Montanari, A. M.; Widmer, W. W. Two new polymethoxylated flavones, a class of compounds with potential anticancer activity, isolated from cold pressed Dancy Tangerine peel oil solids. J. Agric. Food Chem. 1997, 45, 364-368.
5. Collins, S. J.; Ruscetti, F. W.; Gallagher, R. E.; Gallo, R. C. Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds. Proc. Natl. Acad. Sci. U.S.A. 1978, 75, 2458-2462.
6. Deschner, E. E.; Ruperto, J.; Wong, G.; Newmark, H. L. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 1991, 12, 1193-1196.
7. Gentili, B.; Horowitz, R. M. Flavonoids of citrus - VII. Limocitrol and isolimocitrol. Tetrahedron 1964, 20, 2313-2318.
8. Horowitz, R. M. Flavonoids of citrus. I. Isolation of diosmin from lemons (Citrus limon). J. Org. Chem. 1956, 21, 1184-1185.
9. Horowitz, R. M. Flavonoids of citrus. II. Isolation of a new flavonol from lemons. J. Am. Chem. Soc. 1957, 79, 6561-6562.
10. Horowitz, R. M.; Gentili, B. Flavonoid compounds of Citrus. III. Isolation and structure of eriodictyol glycoside. J. Am. Chem. Soc. 1960a, 82, 2803-2806.
11. Horowitz, R. M.; Gentili, B. Flavonoids of citrus. IV. Isolation of some aglycones from the lemon (Citrus lemon). J. Org. Chem. 1960b, 25, 2183-2187.
12. Ito, C.; Fujiwara, K.; Koizumi, M.; Furukawa, H. Isolation and characterization of an antibacterial substance from citrus plant. J. Chinese Chem. Soc. 1998, 45, 89-91.
13. Kanes, K.; Tisserat, B.; Berhow, M.; Vandercook, C. Phenolic composition of various tissues of Rutaceae species. Phytochemistry 1992, 31, 967-974.
14. Park, G. L.; Avery, S. M.; Byers, J. L.; Nelson, D. B. Identification of bioflavonoids from citrus. Food Technol. 1983, 37, 98-105.
15. Stavric, B. Antimutagens and anticarcinogens in foods. Food Chem. Toxicol. 1994, 32, 79-90.
16. Sugiyama, S.; Umehara, K.; Kuroyanagi, M.; Ueno, A.; Taki, T. Studies on the differentiation inducers of myeloid leukemic cells from Citrus species. Chem. Pharm. Bull. 1993, 41, 714-719.
17. Tanaka, T. Misunderstanding with regards citrus classification and nomenclature. Bull. Univ. Osaka Prefect., Ser. B 1969 21, 139.
18. Tanaka, T.; Makita, H.; Kawabata, K.; Mori, H.; Kakumoto, M.; Satoh, K.; Hara, A.; Sumida, T.; Tanaka, T.; Ogawa, H. Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin. Carcinogenesis 1997, 18, 957-965.
19. Vandercook, C. E.; Stevenson, R. G. Lemon juice composition. Identification of the major phenolic compounds and estimation by paper chromatography. J. Agric. Food Chem. 1966, 14, 450-454.
20. Verma, A. K.; Johnson, J. A.; Gould, M. N.; Tanner, M. A. Inhibition of 7,12-dimethylbenz[α]anthracene and N-nitro-methylurea induced rat mammary cancer by dietary flavonol quercetin. Cancer Res. 1988, 48, 5754-5758.
21. Wattenbrug, L. W. Chemoprevention of cancer. Cancer Res. 1985, 45, 1-8.
22. Wattenburg, L. Inhibition of Carcinogenesis by minor anutrient constituents of the diet. Proc. Nutr. Soc. 1990, 49, 173-183.
23. Wei, H.; Tye, L.; Bresnick, E.; Birt, D. F. Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumour promotion in mice. Cancer Res 1990, 50, 499-506.