Nuclear positioning of the BACH2 gene in BCR-ABL positive leukemic cells

Genes Chromosomes and Cancer

Volumn 46, Issue 1, 2007, Pages 67-74

  Ono, Atsushi ^a   Kono, Kazuteru ^a   Ikebe, Dai ^b   Muto, Akihiko ^c   Sun, Jiying ^a   Kobayashi, Masao ^a   Ueda, Kazuhiro ^a   Melo, Junia V ^d   Igarashi, Kazuhiko ^c   Tashiro, Satoshi ^a,e  

^a HIROSHIMA UNIVERSITY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d HAMMERSMITH HOSPITAL   (United Kingdom)

^e HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; IMATINIB; MALEIC ACID DIETHYL ESTER; MESSENGER RNA; PROTEIN BACH2; REPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; B CELL LEUKEMIA; BACH2 GENE; CELL NUCLEUS; CELL STRAIN K 562; CENTROMERE; CHRONIC MYELOID LEUKEMIA; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; GENE; GENE EXPRESSION REGULATION; GENE LOCUS; HETEROCHROMATIN; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; LYMPHOID CELL LINE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE, TUMOR; CELL PROLIFERATION; FUSION PROTEINS, BCR-ABL; HETEROCHROMATIN; HUMANS; K562 CELLS; LEUKEMIA, MYELOID, CHRONIC; MALEATES; PIPERAZINES; PYRIMIDINES; TIME FACTORS; TRANSCRIPTION, GENETIC; U937 CELLS;

EID: 33751089320     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20390     Document Type: Article

References (27)

1. Bolzer A, Kreth G, Solovei I, Koehler D, Saracoglu K, Fauth C, Muller S, Eils R, Cremer C, Speicher MR, Cremer T. 2005, Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol 3:e157.
2. Brown KE, Guest SS, Smale ST, Hahm K, Merkenschlager M, Fisher AG. 1997. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell 91:845-854.
3. Cremer M, von Hase J, Volm T, Brero A, Kreth G, Walter J, Fischer C, Solovei I, Cremer C, Cremer T. 2001. Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells. Chromosome Res 9:541-567.
4. Deininger MW, Goldman JM, Lydon N, Melo JV. 1997. The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells. Blood 90:3691-3698.
5. Deininger MW, Vieira S, Mendiola R, Schultheis B, Goldman JM, Melo JV. 2000. BCR-ABL tyrosine kinase activity regulates the expression of multiple genes implicated in the pathogenesis of chronic myeloid leukemia. Cancer Res 60:2049-2055.
6. Druker BJ, Tamura S, Buchdunger E, Ohno S, Segal GM, Fanning S, Zimmermann J, Lydon NB. 1996. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 2:561-566.
7. Francastel C, Walters MC, Groudine M, Martin DI. 1999. A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin. Cell 99:259-269.
8. Goldman JM, Melo JV. 2003. Chronic myeloid leukemia-Advances in biology and new approaches to treatment. N Engl J Med 349:1451-1464.
9. Hochhaus A, Reiter A, Skladny H, Melo JV, Sick C, Berger U, Guo JQ, Arlinghaus RB, Hehlmann R, Goldman JM, Cross NC. 1996. A novel BCR-ABL fusion gene (e6a2) in a patient with Philadelphia chromosome-negative chronic myelogenous leukemia. Blood 88:2236-2240.
10. Hoshino H, Kobayashi A, Yoshida M, Kudo N, Oyake T, Motohashi H, Hayashi N, Yamamoto M, Igarashi K. 2000. Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element. J Biol Chem 275:15370-15376.
11. Kamio T, Toki T, Kanezaki R, Sasaki S, Tandai S, Terui K, Ikebe D, Igarashi K, Ito E. 2003. B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs. Blood 102:3317-3322.
12. Kosak ST, Groudine M. 2004. Gene order and dynamic domains. Science 306:644-647.
13. Kosak ST, Skok JA, Medina KL, Riblet R, Le Beau MM, Fisher AG, Singh H. 2002. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296:158-162.
14. le Coutre P, Mologni L, Cleris L, Marchesi E, Buchdunger E, Giardini R, Formelli F, Gambacorti-Passerini C. 1999. In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor. J Natl Cancer Inst 91:163-168.
15. Melo JV, Gordon DE, Cross NC, Goldman JM. 1993. The ABL-BCR fusion gene is expressed in chronic myeloid leukemia. Blood 81:158-165.
16. Melo JV, Hughes TP, Apperley JF. 2003. Chronic myeloid leukemia. Hematology Am Soc Hematol Educ Program: 132-152.
17. Muto A, Hoshino H, Madisen L, Yanai N, Obinata M, Karasuyama H, Hayashi N, Nakauchi H, Yamamoto M, Groudine M, Igarashi K. 1998. Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer. EMBO J 17:5734-5743.
18. Muto A, Tashiro S, Nakajima O, Hoshino H, Takahashi S, Sakoda E, Ikebe D, Yamamoto M, Igarashi K. 2004. The transcriptional programme of antibody class switching involves the repressor Bach2. Nature 429:566-571.
19. Muto A, Tashiro S, Tsuchiya H, Kume A, Kanno M, Ito E, Yamamoto M, Igarashi K. 2002. Activatioa of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with promyelocytic leukemia nuclear bodies. J Biol Chem 277:20724-20733.
20. O'Brien S, Tefferi A, Valent P. 2004. Chronic myelogenous leukemia and myeloproliferative disease. Hematology Am Soc Hematol Educ Program:146-162.
21. Oyake T, Itoh K, Motohashi H, Hayashi N, Hoshino H, Nishizawa M. Yamamoto M, Igarashi K. 1996. Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol 16:6083-6095.
22. Sakane-Ishikawa E, Nakatsuka S, Tomita Y, Fujita S, Nakamichi I, Takakuwa T, Sugiyama H, Fukuhara S, Hino M, Kanamaru A, Soma T, Tsukaguchi M. Igarashi K. Kanakura Y, Aozasa K. 2005. Prognostic significance of BACH2 expression in diffuse large B-cell lymphoma: A study of the Osaka Lymphoma Study Group. J Clin Oncol 23:8012-8017.
23. Sasaki S, Ito E, Toki T, Maekawa T, Kanezaki R, Umenai T, Muto A, Nagai H, Kinoshita T, Yamamoto M, Inazawa J, Taketo MM, Nakahata T, Igarashi K, Yokoyama M. 2000. Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15. Oncogene 19:3739-3749.
24. Skok JA, Brown KE, Azuara V, Caparros ML, Baxter J, Takacs K, Dillon N, Gray D, Perry RP, Merkenschlager M, Fisher AG. 2001. Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes. Nat Immunol 2:848-854.
25. Tanabe H, Habermann FA, Solovei I, Cremer M, Cremer T. 2002. Non-random radial arrangements of interphase chromosome territories: Evolutionary considerations and functional implications. Mutat Res 504:37-45.
26. Vieira SA, Deininger MW, Sorour A, Sinclair P, Foroni L, Goldman JM, Melo JV. 2001. Transcription factor BACH2 is transcriptionally regulated by the BCR/ABL oncogene. Genes Chromosomes Cancer 32:353-363.
27. Walter J, Schermelleh L, Cremer M, Tashiro S, Cremer T. 2003. Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages. J Cell Biol 160:685-697.