Sucrose breath testing and intestinal mucositis

Cancer Biology and Therapy

Volumn 5, Issue 9, 2006, Pages 1196-1198

  Keefe, Dorothy M K ^a   Gibson, Rachel J ^b  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Breath tests; Intestinal mucositis; Non invasive tests

Indexed keywords

ANTINEOPLASTIC AGENT; CITRULLINE; MONOCLONAL ANTIBODY; SUCROSE;

BREATH ANALYSIS; CLINICAL TRIAL; DIARRHEA; DISEASE SEVERITY; ENTERITIS; GASTROINTESTINAL ENDOSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTESTINE FUNCTION; MUCOSA INFLAMMATION; NONHUMAN; NOTE; RELIABILITY; REPRODUCIBILITY; RISK FACTOR;

EID: 33751084060     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.5.9.3369     Document Type: Note

References (24)

1. Sonis ST, Elting LS, Keefe DM, Peterson DE, Schubert MM, Hauer-Jenson M, Bekele BN, Raber-Durlacher J, Donnelly JP, Rubenstein E. Perspectives on cancer therapy-induced mucosal injury: Pathogenesis, measurement, epidemiology, and consequences for patients. Cancer 2004; 100:1995-2025.
2. Keefe DM, Cummins AG, Dale BM, Kotasek D, Robb TA, Sage RE. Effect of high-dose chemotherapy on intestinal permeability in humans. Clin Sci 1997; 92:385-9.
3. Bjarnason I. Intestinal permeability. Gut 1994; 35:S18-22.
4. Sonis ST. Mucositis as a biological process: A new hypothesis for the development of chemotherapy-induced stomatotoxicity. Oral Oncol 1998; 34:39-43.
5. Sonis ST, Fey EG. Oral complications of cancer therapy. Oncology 2002; 16:680-95.
6. Sonis ST. The pathobiology of mucositis. Nat Rev: Cancer 2004; 4:277-84.
7. Crosby WH, Kugler HW. Intraluminal biopsy of the small intestine: The intestinal biopsy capsule. Am J Dig Dis 1957; 2:236-41.
8. x CJ, Matsui SM, Lo RS. Etiology and outcome of diarrhoea after marrow transplantation: A prospective study. Gastroenterol 1994; 107:1398-407.
9. Keefe DM, Brealey J, Goland GJ, Cummins AG. Chemotherapy for cancer causes apoptosis that precedes hypoplasia in crypts of the small intestine in humans. Gut 2000; 47:632-7.
10. Miki K, Butler R, Moore D, Davidson G. Rapid and simultaneous quantification of rhamnose, mannitol, and lactulose in urine by HPLC for estimating intestinal permeability in pediatric practice. Clin Chem 1996; 42:71-5.
11. Blijlevens NM, Lutgens LC, Schattenberg AV, Donnelly JP. Citrulline: A potentially simple quantitative marker of intestinal epithelial damage following myeloablative therapy. Bone Marrow Transplant 2004; 34:193-6.
12. Jianfeng G, Weiming Z, Ning L, Fangnan L, Li T, Nan L, Jieshou L. Serum citrulline is a simple quantitative marker for small intestinal enterocytes mass and absorption function in short bowel patients. J Surg Res 2005; 127:177-82.
13. Lutgens LC, Deutz N, Granzier-Peeters M, Beets-Tan R, De Ruysscher D, Gueulette J, Cleutjens J, Berger M, Wouters B, von Meyenfeldt M, Lambin P. Plasma citrulline concentration: A surrogate end point for radiation-induced mucosal atrophy of the small bowel. A feasibility study in 23 patients. Int J Radiat Oncol Biol Phys 2004; 60:275-85.
14. Lutgens LC, Deutz NE, Gueulette J, Cleutjens JP, Berger MP, Wouters BG, von Meyenfeldt MF, Lambin P. Citrulline: A physiologic marker enabling quantitation and monitoring of epithelial radiation-induced small bowel damage. Int J Radiat Oncol Biol Phys 2003; 57:1067-74.
15. Pelton NS, Tivey DR, Howarth GS, Davidson GP, Butler RN. A novel breath test for the noninvasive assessment of small intestinal mucosal injury following methotrexate administration in the rat. Scand J Gastroenterol 2004; 39:1015-6.
16. Clarke JM, Pelton NC, Bajka BH, Howarth GS, Read LC, Butler RN. Use of the 13C-sucrose breath test to assess chemotherapy-induced small intestinal mucositis in the rat. Cancer Biol Ther 2006; 5:34-8.
17. Gibson RJ, Bowen JM, Alvarez E, Finnie JW, Keefe DMK. Establishment of a single dose irinotecan model of gastrointestinal mucositis. Chemotherapy 2006; In press.
18. Gibson RJ, Bowen JM, Inglis MR, Cummins AG, Keefe DMK. Irinotecan causes severe small intestinal damage as well as colonic damage in the rat with implanted breast cancer. J Gastroenterol Hepatol 2003; 18:1095-100.
19. Gibson RJ, Bowen JM, Keefe DM. Palifermin reduces diarrhoea and increases survival following irinotecan treatment in tumour-bearing DA rats. Int J Cancer 2005; 116:464-70.
20. Gibson RJ, Cummins AG, Bowen JM, Logan RM, Healey T, Keefe DMK. Apoptosis occurs early in the basal layer of the oral mucosa following cancer chemotherapy. Asia-Pac J Clin Oncol 2006; 2:39-49.
21. Pritchard DM, Bower L, Potten CS, Jackman AL, Hickman JA. The importance of p53-independent apoptosis in the intestinal toxicity induced by raltitrexed (ZD1694, Tomudex): Genetic differences between BALB/c and DBA/2 mice. Clin Cancer Res 2000; 6:4389-95.
22. Potten CS. Apoptosis in oral mucosa: Lessons from the crypt. A commentary. Oral Dis 2001; 7:81-5.
23. Keefe DM, Gibson RJ, Hauer-Jenson M. Gastrointestinal Mucositis. Sem Oncol Nursing 2004; 20:38-47.
24. Keefe DMK. Mucositis management in patients with cancer. Support Cancer Ther 2006; 3:154-7.