A novel breath test for the non-invasive assessment of small intestinal mucosal injury following methotrexate administration in the rat

Scandinavian Journal of Gastroenterology

Volumn 39, Issue 10, 2004, Pages 1015-1016

  Pelton, N S ^b   Tivey, D R ^b   Howarth, G S ^b   Davidson, G P ^b   Butler, R N ^a  

^a WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE; SUCRASE; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREATH ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ASSAY; EXHALATION; GASTROINTESTINAL TOXICITY; HISTOPATHOLOGY; INTESTINE BRUSH BORDER; INTESTINE INJURY; MALE; MASS SPECTROMETRY; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SCORING SYSTEM; SMALL INTESTINE MUCOSA;

ANALYSIS OF VARIANCE; ANIMALS; BREATH TESTS; DISEASE MODELS, ANIMAL; INJECTIONS, SUBCUTANEOUS; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; METHOTREXATE; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SUCROSE;

EID: 6344278841     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365520410003416     Document Type: Article

References (5)

1. Gray GM. Carbohydrate digestion and absorption. Role of the small intestine. N Engl J Med 1975;292:1225-30.
2. Davidson GP, Barnes GL. Structural and functional abnormalities of the small intestine in infants and young children with rotavirus enteritis. Acta Paediatr Scand 1979;68:181-6.
3. Hyams JS, Batrus CL, Grand RJ, Sallan SE. Cancer chemotherapy-induced lactose malabsorption in children. Cancer 1982;49:646-50.
4. 13C. J Pediatr Gastroenterol Nutr 1985;4:9-19.
5. Howarth GS, Francis GL, Cool JC, Xu X, Byard RW, Read LC. Milk growth factors enriched from cheese whey ameliorate intestinal damage by methotrexate when administered orally to rats. J Nutr 1996;126:2519-30.