Inhibition of human 5-lipoxygenase and anti-neoplastic effects by 2-amino-1,4-benzoquinones

Medicinal Chemistry

Volumn 2, Issue 6, 2006, Pages 591-595

  Poeckel, Daniel ^a   Niedermeyer, Timo H J ^b   Pham, Hang T L ^b   Mikolasch, Annett ^b   Mundt, Sabine ^b   Lindequist, Ulrike ^b   Lalk, Michael ^b   Werz, Oliver ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Aminoquinones; Antineoplastic activity; Cancer; Lipoxygenase

Indexed keywords

1,4 BENZOQUINONE DERIVATIVE; 2 AMINO 1,4 BENZOQUINONE DERIVATIVE; 2 [4' (ISOPROPYLPHENYL)AMINO] 5,6 DIMETHYL 1,4 BENZOQUINONE; ANTINEOPLASTIC AGENT; ARACHIDONATE 5 LIPOXYGENASE; LIPOXYGENASE INHIBITOR; UNCLASSIFIED DRUG;

ADULT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BLADDER CANCER; BREAST CANCER; CANCER CELL CULTURE; CELL FREE SYSTEM; CELL STRAIN MCF 7; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME ISOLATION; FIBROBLAST; HUMAN; HUMAN CELL; IC 50; NEUTROPHIL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 33751057513     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/1573406410602060591     Document Type: Article

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