The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease

Nucleic Acids Research

Volumn 34, Issue 18, 2006, Pages 5325-5336

  Georg, Jens ^a   Schomacher, Lars ^a   Chong, James P J ^b   Majerník, Alan I ^b   Raabe, Monika ^c   Urlaub, Henning ^c   Müller, Sabine ^d   Ciirdaeva, Elena ^a   Kramer, Wilfried ^a   Fritz, Hans Joachim ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF YORK   (United Kingdom)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^d RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE; DOUBLE STRANDED DNA; NUCLEOTIDE; PROTEIN MTH212; UNCLASSIFIED DRUG; URACIL; URIDINE;

ARCHAEBACTERIUM; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; DNA REPAIR; ENZYME ACTIVITY; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE INSERTION; GENE ISOLATION; METHANOTHERMOBACTER THERMAUTOTROPHICUS; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; CATALYSIS; CELL EXTRACTS; CLONING, MOLECULAR; DNA; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASES; GENES, ARCHAEAL; METHANOBACTERIACEAE; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; URIDINE;

ESCHERICHIA COLI; HOMO SAPIENS; METHANOSARCINA MAZEI; METHANOTHERMOBACTER THERMAUTOTROPHICUS;

EID: 33751012715     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl604     Document Type: Article

References (30)

1. Lindahl,T. (1974) An N-glycosidase from E.coli that releases free uracil from DNA containing deaminated cytosine residues. Proc. Natl Acad. Sci. USA, 71, 3649-3653.
2. Horst,J.P. and Fritz,H.J. (1996) Counteracting the mutagenic effect of hydrolytic deamination of DNA 5-methylcytosine residues at high temperature: DNA mismatch N-glycosylase Mig.Mth of the thermophilic archaeon Methanobacterium thermoautotrophicum THF. EMBO J., 15, 5459-5469.
3. Yang,H., Fitz-Gibbon,S., Marcotte,E.M., Tai,J.H., Hyman,E.C. and Miller,J.H. (2000) Characterization of a thermostable DNA glycosylase specific for U/G and T/G mismatches from the hyperthermophilic archaeon Pyrobaculum aerophilum. J. Bacteriol., 182, 1272-1279.
4. Chung,J.H., Im,E.K., Park,H.Y., Kwon,J.H., Lee,S., Oh,J., Hwang,K.C., Lee,J.H. and Jang,Y. (2003) A novel uracil-DNA glycosylase family related to the helix-hairpin-helix DNA glycosylase superfamily. Nucleic Acids Res., 31, 2045-2055.
5. Sandigursky,M. and Franklin,W.A. (1999) Thermostable uracil-DNA glycosylase from Thermotoga maritima a member of a novel class of DNA repair enzymes. Curr. Biol., 9, 531-534.
6. Sartori,A.A., Fitz-Gibbon,S., Yang,H., Miller,J.H. and Jiricny,J. (2002) A novel uracil-DNA glycosylase with broad substrate specificity and an unusual active site. EMBO J., 21, 3182-3191.
7. Starkuviene,V. and Fritz,H.J. (2002) A novel type of uracil-DNA glycosylase mediating repair of hydrolytic DNA damage in the extremely thermophilic eubacterium Thermus thermophilus. Nucleic Acids Res., 30, 2097-2102.
8. Smith,D.R., Doucette-Stamm,L.A., Deloughery,C., Lee,H., Dubois,J., Aldredge,T., Bashirzadeh,R., Blakely,D., Cook,R., Gilbert,K. et al. (1997) Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: Functional analysis and comparative genomics. J. Bacteriol., 179, 7135-7155.
9. Sandigursky,M. and Franklin,W.A. (2000) Uracil-DNA glycosylase in the extreme thermophile Archaeoglobus fulgidus. J. Biol. Chem., 275, 19146-19149.
10. Sartori,A.A., Schar,P., Fitz-Gibbon,S., Miller,J.H. and Jiricny,J. (2001) Biochemical characterization of uracil processing activities in the hyperthermophilic archaeon Pyrobaculum aerophilum. J. Biol. Chem., 276, 29979-29986.
11. Pfeifer,S. and Greiner-Stoffele,T. (2005) A recombinant exonuclease III homologue of the thermophilic archaeon Methanothermobacter thermautotrophicus. DNA Repair (Amst.), 4, 433-444.
12. Bullock,W.O., Fernandez,J.M. and Short,J.M. (1987) XL1-blue: A high efficiency plasmid transforming recA Escherichia coli strain with beta-galactosidase selection. Biotechniques, 5, 376-378.
13. Guy,C.P., Majernik,A.I., Chong,J.P. and Bolt,E.L. (2004) A novel nuclease-ATPase (Nar71) from archaea is part of a proposed thermophilic DNA repair system. Nucleic Acids Res., 32, 6176-6186.
14. McBride,L.J. and Caruthers,M.H. (1983) An investigation of several deoxynucleotide phosphoramidites. Tetrahedron Lett., 24, 245-248.
15. Sinha,N.D., Biernat,J., McManus,J. and Koster,H. (1984) Polymer support oligonucleotide synthesis XVIII: Use of beta-cyanoethyl-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product. Nucleic Acids Res., 12, 4539-4557.
16. Datsenko,K.A. and Wanner,B.L. (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl Acad. Sci. USA, 97, 6640-6645.
17. Laemmli,U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
18. Blum,H., Beier,H. and Gross,H.J. (1987) Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels. Electrophoresis, 8, 93-99.
19. Shevchenko,A., Wilm,M., Vorm,O. and Mann,M. (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem., 68, 850-858.
20. Vorm,O., Roepstorff,P. and Mann,M. (1994) Improved Resolution and very high sensitivity in MALDI TOF of matrix surfaces made by fast evaporation. Anal. Chem., 66, 3281-3287.
21. Wang,Z.G., Smith,D.G. and Mosbaugh,D.W. (1991) Overproduction and characterization of the uracil-DNA glycosylase inhibitor of bacteriophage PBS2. Gene, 99, 31-37.
22. 2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: New insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis. J. Mol. Biol., 290, 447-457.
23. SantaLucia,J., Jr (1998) A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. Proc. Natl Acad. Sci. USA, 95, 1460-1465.
24. Hofacker,I.L. (2003) Vienna RNA secondary structure server. Nucleic Acids Res., 31, 3429-3431.
25. Zeikus,J.G. and Wolfe,R.S. (1972) Methanobacterium thermoautotrophicus sp. n., an anaerobic, autotrophic, extreme thermophile. J. Bacteriol., 109, 707-715.
26. Gros,L., Ishchenko,A.A., Ide,H., Elder,R.H. and Saparbaev,M.K. (2004) The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway. Nucleic Acids Res., 32, 73-81.
27. Rothwell,D.G., Hang,B., Gorman,M.A., Freemont,P.S., Singer,B. and Hickson,I.D. (2000) Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding. Nucleic Acids Res., 28, 2207-2213.
28. Deppenmeier,U., Johann,A., Hartsch,T., Merkl,R., Schmitz,R.A., Martinez-Arias,R., Henne,A., Wiezer,A., Baumer,S., Jacobi,C. et al. (2002) The genome of Methanosarcina mazei: Evidence for lateral gene transfer between bacteria and archaea. J. Mol. Microbiol. Biotechnol., 4, 453-461.
29. Savva,R., McAuley-Hecht,K., Brown,T. and Pearl,L. (1995) The structural basis of specific base-excision repair by uracil-DNA glycosylase. Nature, 373, 487-493.
30. Slupphaug,G., Mol,C.D., Kavli,B., Arvai,A.S., Krokan,H.E. and Tainer,J.A. (1996) A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature, 384, 87-92.