β 3-Adrenoceptor agonist stimulation of the Na +,K +-pump in rat skeletal muscle is mediated by β 2- rather than β 3-adrenoceptors

British Journal of Pharmacology

Volumn 149, Issue 6, 2006, Pages 635-646

  Murphy, K T ^a   Bundgaard, H ^b   Clausen, T ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b Rigshospitalet   (Denmark)

Author keywords

1 adrenoceptors; 2 adrenoceptors; 3 adrenoceptors; BRL 37344; Na +content; Na +,K + pump; Nitric oxide; Ouabain suppressible 86Rb + uptake; Skeletal muscle

Indexed keywords

1 (2 ETHYLPHENOXY) 3 (1,2,3,4 TETRAHYDRO 1 NAPHTHYLAMINO) 2 PROPANOL OXALATE; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY] PROPYL]AMINO]ETHOXY]SALICYLAMIDE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 3 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; N(G) NITROARGININE METHYL ESTER; NADOLOL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OUABAIN; POTASSIUM ION; RUBIDIUM 86; SODIUM ION; UNCLASSIFIED DRUG; BETA ADRENERGIC RECEPTOR STIMULATING AGENT;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; FLAME PHOTOMETRY; HOMEOSTASIS; MUSCLE FORCE; NONHUMAN; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SODIUM CELL LEVEL; SOLEUS MUSCLE; TIME; ANIMAL; PHYSIOLOGY; WISTAR RAT;

ADRENERGIC BETA-AGONISTS; ANIMALS; NA(+)-K(+)-EXCHANGING ATPASE; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, ADRENERGIC, BETA-3;

EID: 33750989613     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706896     Document Type: Article

References (56)

1. Arch JR, Ainsworth AT, Ellis RD, Piercy V, Thody VE, Thurlby PL et al. (1984). Treatment of obesity with thermogenic β-adrenoceptor agonists: studies on BRL 26830A in rodents. Int J Obes 8: 1-11.
2. Arch JR, Kaumann AJ (1993). β3 and atypical β-adrenoceptors. Med Res Rev 13: 663-729.
3. 3-adrenoceptor agonists in the treatment of obesity and diabetes. Int J Obes Relat Metab Disord 20: 191-199.
4. 3-adrenergic receptor. Taylor and Francis: London, pp 48-76.
5. Badawi JK, Uecelehan H, Hatzinger M, Michel MS, Haferkamp A, Bross S (2005). Relaxant effects of β-adrenergic agonists on porcine and human detrusor muscle. Acta Physiol Scand 185: 151-159.
6. 3 adrenoceptors. Br J Pharmacol 144: 317-322.
7. Barouch LA, Harrison RW, Skaf MW, Rosas GO, Cappola TP, Kobeissi ZA et al. (2002). Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature 416: 337-339.
8. +-ATPase activity through cyclic GMP-protein kinase G dependent mechanism. J Physiol Pharmacol 54: 191-210.
9. Board M, Doyle P, Cawthorne MA (2000). BRL37344, but not CGP12177, stimulates fuel oxidation by soleus muscle in vitro. Eur J Pharmacol 406: 33-40.
10. Bond RA, Clarke DE (1988). Agonist and antagonist characterization of a putative adrenoceptor with distinct pharmacological properties from the α- and β-subtypes. Br J Pharmacol 95: 723-734.
11. Broadley KJ (2006). β-adrenoceptor responses of the airways: for better or worse? Eur J Pharmacol 533: 15-27.
12. + pump in rat soleus muscle. J Physiol 545: 229-240.
13. + pump. Biophys J 90: 556A.
14. Bundgaard H, Garcia A, Tinworth KD, Huang Y, Hunyor S, Rasmussen HH (2006b). The haemodynamic effect of BRL-37344 in sheep before and after heart failure. Biophys J 90: 558A.
15. 3- adrenoceptor in human adipose tissue, atrium and skeletal muscle. Int J Obes Relat Metab Disord 23: 1057-1065.
16. + pump regulation and skeletal muscle contractility. Physiol Rev 83: 1269-1324.
17. +-paralysed rat muscle. J Physiol 472: 521-536.
18. Clausen T, Everts ME, Kjeldsen K (1987). Quantification of the maximum capacity for active sodium-potassium transport in rat skeletal muscle. J Physiol 388: 163-181.
19. Clausen T, Flatman JA (1977). The effect of catecholamines on Na-K transport and membrane potential in rat soleus muscle. J Physiol 270: 383-414.
20. 2-adrenoceptors mediate the stimulating effect of adrenaline on active electrogenic Na-K-transport in rat soleus muscle. Br J Pharmacol 68: 749-755.
21. Clausen T, Kohn PG (1977). The effect of insulin on the transport of sodium and potassium in rat soleus muscle. J Physiol 265: 19-42.
22. 3-adrenoceptor in intact human adipocytes and ventricular myocardium: effect of obesity and treatment with ephedrine and caffeine. Int J Obes Relat Metab Disord 26: 1442-1450.
23. Dolan JA, Muenkel HA, Burns MG, Pellegrino SM, Fraser CM, Pietri F et al. (1994). Beta-3 adrenoceptor selectivity of the dioxolane dicarboxylate phenethanolamines. J Pharmacol Exp Ther 269: 1000-1006.
24. 2-adrenoceptors. Eur J Pharmacol 130: 137-139.
25. 3-adrenoceptor mRNA in rat tissues. Br J Pharmacol 117: 210-216.
26. Everts ME, Clausen T (1992). Activation of the Na-K pump by intracellular Na in rat slow- and fast-twitch muscle. Acta Physiol Scand 145: 353-362.
27. Garthwaite J, Southam E, Boulton CL, Nielsen EB, Schmidt K, Mayer B (1995). Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol Pharmacol 48: 184-188.
28. 3-adrenoceptor agonists. J Pharmacol Exp Ther 290: 687-693.
29. 3-adrenergic receptor. Mol Pharmacol 40: 895-899.
30. Hoffmann C, Leitz MR, Oberdorf-Maass S, Lohse MJ, Klotz KN (2004). Comparative pharmacology of human β-adrenergic receptor subtypes-characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol 369: 151-159.
31. Holm P, Kankaanranta H, Metsa-Ketela T, Moilanen E (1998). Radical releasing properties of nitric oxide donors GEA 3162, SIN-1 and S-nitroso-N-acetylpenicillamine. Eur J Pharmacol 346: 97-102.
32. 3-adrenoceptor in the rat. Br J Pharmacol 118: 2085-2098.
33. Kobzik L, Reid MB, Bredt DS, Stamler JS (1994). Nitric oxide in skeletal muscle. Nature 372: 546-548.
34. Langin D, Portillo MP, Saulnier-Blache JS, Lafontan M (1991). Coexistence of three β-adrenoceptor subtypes in white fat cells of various mammalian species. Eur J Pharmacol 199: 291-301.
35. +-ATPase. Am J Physiol 284: C1550-C1560.
36. Liu YL, Cawthorne MA, Stock MJ (1996). Biphasic effects of the β-adrenoceptor agonist, BRL 37344, on glucose utilization in rat isolated skeletal muscle. Br J Pharmacol 117: 1355-1361.
37. McKee M, Scavone C, Nathanson JA (1994). Nitric oxide, cGMP, and hormone regulation of active sodium transport. Proc Natl Acad Sci USA 91: 12056-12060.
38. 3-adrenergic receptor subtype transcripts in porcine tissues. J Anim Sci 77: 611-621.
39. +-ATPase activity. Nitric Oxide 4: 333-342.
40. 3-adrenergic agonist, inhibits protein breakdown in rat skeletal muscle. Pflügers Arch 451: 617-624.
41. + transport in the maintenance of contractility in rat skeletal muscle. Acta Physiol Scand 157: 199-209.
42. 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes. Mol Pharmacol 49: 7-14.
43. Nordsborg N, Mohr M, Pedersen LD, Nielsen JJ, Langberg H, Bangsbo J (2003). Muscle interstitial potassium kinetics during intense exhaustive exercise: effect of previous arm exercise. Am J Physiol 285: R143-R148.
44. 2-selective adrenoceptor antagonist and can be used to characterize β-adrenoceptor populations in tissues. Life Sci 27: 671-677.
45. Rees DD, Palmer RM, Schulz R, Hodson HF, Moncada S (1990). Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 101: 746-752.
46. Reid MB, Kobzik L, Bredt DS, Stamler JS (1998). Nitric oxide modulates excitation-contraction coupling in the diaphragm. Comp Biochem Physiol A Mol Integr Physiol 119: 211-218.
47. 3-adrenoceptors in plasma potassium control in conscious rabbits. J Auton Pharmacol 13: 227-236.
48. + channels in rat skeletal muscle. Am J Physiol 271: C971-C981.
49. Sejersted OM, Sjøgaard G (2000). Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise. Physiol Rev 80: 1411-1481.
50. 3-adrenoceptors compared in brown adipose tissue and in skeletal muscle membranes. Br J Pharmacol 109: 1157-1163.
51. 3-adrenergic receptor mRNA expression in adipose and other metabolic tissues in the adult human. Mol Pharmacol 43: 343-348.
52. + pump in isolated rabbit cardiac myocytes. J Physiol 565: 815-825.
53. Yen TT, McKee MM, Stamm NB (1984). Thermogenesis and weight control. Int J Obes 8: 65-78.
54. Young ME, Leighton B (1998a). Evidence for altered sensitivity of the nitric oxide/cGMP signalling cascade in insulin-resistant skeletal muscle. Biochem J 329: 73-79.
55. Young ME, Leighton B (1998b). Fuel oxidation in skeletal muscle is increased by nitric oxide/cGMP - evidence for involvement of cGMP-dependent protein kinase. FEBS Lett 424: 79-83.
56. Zhou L, Burnett AL, Huang PL, Becker LC, Kuppusamy P, Kass DA et al. (2002). Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle. Biochem Biophys Res Commun 294: 1030-1035.