BRL37344, but not CGP12177, stimulates fuel oxidation by soleus muscle in vitro

European Journal of Pharmacology

Volumn 406, Issue 1, 2000, Pages 33-40

  Board, Mary ^a   Doyle, Patrick ^b   Cawthorne, Michael A ^a  

^a UNIVERSITY OF BUCKINGHAM   (United Kingdom)

^b NOVO NORDISK A S   (Denmark)

Author keywords

3 Adrenoceptor agonists; Glucose metabolism; Isolated; Pyruvate oxidation; Soleus muscle; Thermogenesis

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; BETA 3 ADRENERGIC RECEPTOR; DEOXYGLUCOSE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PYRUVIC ACID;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENZYME INHIBITION; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; SKELETAL MUSCLE; SOLEUS MUSCLE; THERMOGENESIS;

ADRENERGIC BETA-AGONISTS; ANIMALS; CARBON DIOXIDE; CARBON RADIOISOTOPES; CITRIC ACID CYCLE; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ETHANOLAMINES; GLUCOSE; GLUCOSE-6-PHOSPHATE; INDOLES; ISOQUINOLINES; MICE; MICE, OBESE; MUSCLE, SKELETAL; OXIDATION-REDUCTION; PALMITATES; PHOSPHORYLATION; PROPANOLAMINES; PROTEIN KINASE C; PYRUVIC ACID; SULFONAMIDES;

EID: 0034613404     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00671-3     Document Type: Article

References (36)

1. 3-adrenergic agonist, BRL 35135A, on glucose uptake in rat skeletal muscle in vivo and in vitro. J. Endocrinol. 139:1993;479-486.
2. Arch J.R.S., Ainsworth A.T.S., Cawthorne M.A., Piercy V., Sennitt M.V., Thody V.E., Wilson C., Wilson S. Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs. Nature. 309:1984;163-165.
3. Avignon A., Yamada K., Zhou X., Spencer B., Cardona O., Saba-Siddique S., Galloway K., Standaert M.L., Farese R.V. Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakazaki (GK) obese/aged and obese/Zucker rats: a mechanism for inhibiting glycogen synthesis. Diabetes. 45:1996;1396-1404.
4. Berkowitz D.E., Nardone N.A., Smiley R.M., Price D.T., Kreutter D.K., Fremeau R.T., Schwinn D.A. Distribution of beta-3-adrenoceptor mRNA in human tissues. Eur. J. Pharmacol. 289:1995;223-228.
5. 3 receptors. J. Med. Chem. 35:1992;3081-3084.
6. Boss O., Samec S., Paoloni-Giacobino A., Rossier C., Dulloo A., Seydoux J., Muzzin P., Giacobino J.-P. Uncoupling protein 3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett. 408:1997;39-42.
7. 3 adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator activated receptor - γ coactivator 1. Biochem. Biophys. Res. Commun. 261:1999;870-876.
8. Challis R.A.J., Leighton B., Wilson S., Thurlby P., Arch J. An investigation of the β-adrenoceptor that mediates metabolic responses to the novel agonist BRL 28410 in rat soleus muscle. Biochem. Pharmacol. 37:1988;947-950.
9. 3-adrenoceptor in human adipose tissue, atrium and skeletal muscle. Int. J. Obes. 23:1999;1057-1065.
10. Curi R., Newsholme P., Newsholme E.A. Metabolism of pyruvate by isolated rat mesenteric lymphocytes, lymphocyte mitochondria and isolated mouse macrophages. Biochem. J. 250:1988;383-388.
11. Dimitriadis G., Leighton B., Parry-Billings M., Sasson S., Young M., Krause U., Bevan S., Piva T., Wegener G., Newsholme E.A. Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle. Biochem. J. 221:1997;707-712.
12. Espinal J., Dohm G.L., Newsholme E.A. Sensitivity to insulin of glycolysis and glycogen synthesis of isolated soleus muscle strips from sedentary, exercised and exercised trained rats. Biochem. J. 212:1983;453-456.
13. 3-adrenoceptor mRNA in rat tissues. Br. J. Pharmacol. 117(1):1996;210-216.
14. Findik D., Song Q.Z., Hidaka H., Lavin M. Protein kinase A inhibitors enhance radiation-induced apoptosis. J. Cell. Biochem. 57(1):1995;12-21.
15. 4-adrenoceptor. Br. J. Pharmacol. 122(6):1997;1244-1250.
16. 3-adrenergic agonists and leptin. J. Biol. Chem. 272(39):1997;24129-24132.
17. Issad T., Penicaud L., Ferre P., Kande J., Baudon M.A., Girard J. Effects of fasting on tissue glucose utilization in conscious resting rats. Biochem. J. 246:1987;241-244.
18. 3-adrenergic independent effects of CGP12177 in brown adipose tissue. Mol. Pharmacol. 57:2000;252-258.
19. Kaumann A.J. Four beta-adrenoceptor sub-types in the mammalian heart. Trends Pharmacol. Sci. 18:1997;70-76.
20. Liu Y.-L., Stock M.J. Acute effects of the beta-3 adrenoceptor agonist, BRL35135, on tissue glucose utilisation. Br. J. Pharmacol. 114:1995;888-894.
21. Liu Y.-L., Cawthorne M.A., Stock M.J. Biphasic effects of the β-adrenceoptor agonist, BRL37344, on glucose utilisation in rat isolated skeletal muscle. Br. J. Pharmacol. 117:1996;1355-1361.
22. 3-adrenoceptor induces activation of CAMP-dependent protein kinase with activation of lipolysis in rat white adipocytes. Biochem. Pharmacol. 46:1993;575-581.
23. Nicholls D.G., Snelling R., Rial E. Proton and calcium circuits across the inner mitochondrial membrane. Biochem. Soc. Trans. 12(3):1984;388-390.
24. 3-adrenoceptor knockout mice: evidence for a new β-adrenergic receptor in brown adipose tissue. Br. J. Pharmacol. 124:1998;1684-1688.
25. Ricquier D., Bouilaud F., Toumelin P., May G., Bazin R., Arch J., Pericaud L. Expression of uncoupling protein mRNA in thermogenic or weakly thermogenic brown adipose tissue. J. Biol. Chem. 261(30):1986;13905-13910.
26. 3-adrenoceptors. Eur. J. Pharmacol. 348:1998;53-60.
27. 125I]-cyanopindolol binding sites in rat soleus muscle. Br. J. Pharmacol. 109:1993;344-352.
28. 1/1-) and atypical β-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel β-adrenoceptor agonists of differing selectivities. J. Pharmacol. Exp. Ther. 285(3):1998;1084-1095.
29. 3-adrenoceptors compared in brown adipose tissue and in skeletal muscle membranes. Br. J. Pharmacol. 109:1993;1157-1163.
30. 3-adrenergic agonist BRL37344 increases glucose transport into L6 myocytes through a mechanism different from that of insulin. J. Biochem. 122:1997;90-95.
31. Thomas R.F., Liggett S.B. Lack of beta-3-adrenergic receptor mRNA expression in adipose and other metabolic tissues in the adult human. Mol. Pharmacol. 43:1993;343-348.
32. Thurlby P.A., Ellis R.D.M. Differences between the effects of noradrenaline and the β-adrenoceptor agonist, BRL21410, in brown adipose tissue and hind limb of the anaesthetised rat. Can. J. Physiol. 64:1986;1111-1114.
33. Tsuboyama-Kasaoka N., Tsunoda N., Maruyama K., Takahashi M., Kim H., Ikemoto S., Ezaki O. Upregulation of uncoupling protein 3 (UCP3) mRNA by exercise training and down-regulation of UCP3 by denervation in skeletal muscles. Biochem. Biophys. Res. Commun. 247:1998;498-503.
34. Van Liefde I., Van Witzenburg A., Vauquelin G. Isoproterenol and selective agonists stimulate similar atypical β-adrenoceptor in rat adipocytes. Biochem. Pharmacol. 45:1993;974-977.
35. Vidal-Puig A., Solanes G., Grujic D., Flier J.S., Lowell B.B. UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem. Biophys. Res. Commun. 235:1997;79-82.
36. Wilson C., Wilson S., Piercy V., Sennitt M.V., Arch J.R. The rat lipolytic beta-adrenoceptor studies using novel beta-adrenoceptor agonists. Eur. J. Pharmacol. 100(3-4):1984;309-319.