Functional characterization of iron-substituted tristetraprolin-2D (TTP-2D, NUP475-2D): RNA binding affinity and selectivity

Biochemistry

Volumn 45, Issue 45, 2006, Pages 13641-13649

  DiTargiani, Robert C ^a   Lee, Seung Jae ^a   Wassink, Sarah ^a   Michel, Sarah L J ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CLONING; ESCHERICHIA COLI; IRON COMPOUNDS; RNA; SUBSTITUTION REACTIONS;

MICROMOLAR AFFINITY; RNA-BINDING SEQUENCES; TRISTETRAPROLIN (TTP); VISIBLE RED COLORATION;

PROTEINS;

ADENINE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; IRON; MESSENGER RNA; METAL ION; NUCLEIC ACID; REGULATOR PROTEIN; TRISTETRAPROLIN; ZINC; ZINC FINGER PROTEIN;

3' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CANONICAL ANALYSIS; COMPLEX FORMATION; ESCHERICHIA COLI; GENE CONSTRUCT; GENE OVEREXPRESSION; INFLAMMATION; IRON BINDING CAPACITY; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RNA BINDING; RNA SEQUENCE; SEQUENCE ANALYSIS; TITRIMETRY;

ANIMALS; ANISOTROPY; BASE SEQUENCE; CLONING, MOLECULAR; COBALT; FERRIC COMPOUNDS; FERROUS COMPOUNDS; IRON; MICE; RNA, MESSENGER; SPECTROPHOTOMETRY; TRISTETRAPROLIN; ZINC;

EID: 33750986508     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060747n     Document Type: Article

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