N-Glycan Structure Analysis Using Lectins and an α-Mannosidase Activity Assay

Methods in Enzymology

Volumn 416, Issue , 2006, Pages 304-314

  Akama, Tomoya O ^a   Fukuda, Michiko N ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA MANNOSIDASE; GLYCAN; LECTIN; RECOMBINANT ENZYME;

ANIMAL CELL; ANIMAL TISSUE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SPECIFICITY; EXPRESSION VECTOR; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOCHEMISTRY; IMMUNOBLOTTING; KNOCKOUT MOUSE; MAMMAL CELL; MASS SPECTROMETRY; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRUCTURE ANALYSIS;

ALPHA-MANNOSIDASE; ANIMALS; ANIMALS, NEWBORN; CERCOPITHECUS AETHIOPS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COS CELLS; ENZYME ACTIVATION; HISTOCYTOCHEMISTRY; HISTOCYTOLOGICAL PREPARATION TECHNIQUES; LECTINS; MASS SPECTROMETRY; MICE; MICE, KNOCKOUT; POLYSACCHARIDES; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 33750969050     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(06)16020-6     Document Type: Review

References (21)

1. Akama T.O., Nakagawa H., Sugihara K., Narisawa S., Ohyama C., Nishimura S., O'Brien A.D., Moremen K.W., Millan J.L., and Fukuda M.N. Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science 295 (2002) 124-127
2. X in N-glycan processing in vivo in mice. Proc. Natl. Acad. Sci. USA 103 24 (2006) 8983-8988
3. Angata K., Yen T.-Y., El-Battari A., Macher B.A., and Fukuda M. Unique disulfide bond structures found in ST8SiaIV polysialyl-transferase are required for activity. J. Biol. Chem. 276 (2001) 15369-15377
4. Bonay P., and Hughes R.C. Purification and characterization of a novel broad-specificity (alpha 1-2, alpha 1-3 and alpha 1-6) mannosidase from rat liver. Eur. J. Biochem. 197 (1991) 229-238
5. Bonay P., Roth J., and Hughes R.C. Subcellular distribution in rat liver of a novel broad-specificity (alpha 1-2, alpha 1-3 and alpha 1-6) mannosidase active on oligomannose glycans. Eur. J. Biochem. 205 (1992) 399-407
6. Chui D., Oh-eda M., Liao Y.-F., Penneerselvan K., Lal A., Marek K.W., Freeze H., Moremen K.W., Fukuda M.N., and Marth J.D. Alpha-mannosidase-II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis. Cell 90 (1997) 157-167
7. Harpaz N., and Schachter H. Control of glycoprotein synthesis. Bovine colostrum UDP-N-acetylglucosamine:alpha-D-mannoside beta 2-N-acetylglucosaminyltransferase I. Separation from UDP-N-acetylglucosamine:Alpha-D-mannoside beta 2-N-acetylglucosaminyltransferase II, partial purification, and substrate specificity. J. Biol. Chem. 255 (1980) 4885-4893
8. Ioffe E., and Stanley P. Mice lacking N-acetylglucosaminyltransferase I activity die at midgestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc. Natl. Acad. Sci. USA 91 (1994) 728-732
9. Kornfeld R., and Kornfeld S. Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem. 54 (1985) 631-664
10. Metzler M., Gertz A., Sarker M., Schachter H., Scrader J.M., and Marth J.D. Complex asparagine-linked oligosaccharides required for morphogenic events during post-implantation development. EMBO J. 13 (1994) 2056-2065
11. Misago M., Liao Y.-F., Kudo S., Eto S., Mattei M.-G., Moremen K.W., and Fukuda M.N. Molecular cloning and expression of cDNAs encoding human α-mannosidase II and a novel α-mannosidase IIx isozyme. Proc. Natl. Acad. Sci. USA 92 (1995) 11766-11770
12. Moremen K.W., Trimble R.B., and Herscovics A. Glycosidases of asparagine-linked oligosaccharide processing pathway. Glycobiology 4 (1994) 113-125
13. Oh-Eda M., Nakagawa H., Akama T.O., Lowitz K., Misago M., Moremen K.W., and Fukuda M.N. Overexpression of the Golgi-localized enzyme alphamannosidase IIx in Chinese hamster ovary cells results in the conversion of hexamannosyl-N-acetylchitobiose to tetramannosyl-N-acetylchitobiose in the N-glycan-processing pathway. Eur. J. Biochem. 268 (2001) 1280-1288
14. Schachter H. The "yellow brick road" to branched complex N-glycans. Glycobiology 1 (1991) 453-461
15. Schachter H., and Jaeken J. Carbohydrate-deficient glycoprotein syndrome type II. Biochim. Biophys. Acta 1455 (1999) 179-192
16. Schachter H., Narashimhan S., Gleeson P., and Vella G. Control of branching during the biosynthesis of asparagine-linked oligosaccharides. Can. J. Biochem. 61 (1983) 1049-1066
17. Tan J., Jaeken J., and Schachter H. Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development. Am. J. Hum. Genet. 59 (1996) 810-817
18. Tulsiani D.R., Hubbard S.C., Robbins P.W., and Touster O. Alpha-D-mannosidases of rat liver Golgi membranes. Mannosidase II is the GlcNAcMAN5cleaving enzyme in glycoprotein biosynthesis and mannosidases Ia and Ib are the enzymes converting Man9 precursors to Man5 intermediates. J. Biol. Chem. 257 (1982) 3660-3668
19. Vaitaitis G.M., Sanderson R.J., Kimble E.J., Elkins N.D., and Flores S.C. Modification of enzyme-conjugated streptavidin-biotin Western blot technique to avoid detection of endogenous biotin-containing proteins. BioTechniques 26 (1999) 854-858
20. Wang Y., Schachter H., and Marth J.D. Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II: A model for congenital disorder of glycosylation type IIa. Biochim. Biophys. Acta 1573 (2002) 301-311
21. Wang Y., Tan J., Sutton-Smith M., Ditto D., Panico M., Campbell R.M., Varki N.M., Long J.M., Jaeken J., Levinson S.R., Wynshaw-Boris A., Morris H.R., Le D., Dell A., Schachter H., and Marth J.D. Modeling human congenital disorder of glycosylation type IIa in the mouse: Conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. Glycobiology 11 (2001) 1051-1070