Hyperinsulinemia in healthy children and adolescents with a positive family history for type 2 diabetes

Pediatrics

Volumn 118, Issue 5, 2006, Pages

  Rodríguez Morán, Martha ^a   Guerrero Romero, Fernando ^b,c  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^b Research Group on Diabetes and Chronic Illnesses   (Mexico)

^c NONE   (Mexico)

Author keywords

Diabetes mellitus; Epidemiology; Family issues; Obesity

Indexed keywords

INSULIN; TRIACYLGLYCEROL;

ADOLESCENT; ADULT; ANTHROPOMETRY; ARTICLE; BODY FAT; BODY MASS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; HUMAN; HYPERINSULINEMIA; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MEXICO; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PREVALENCE; PRIMARY SCHOOL; PRIORITY JOURNAL; SCHOOL CHILD; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; CHILD; CROSS-SECTIONAL STUDY; GENETICS; HYPERINSULINISM;

ADOLESCENT; CHILD; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; HYPERINSULINISM; MALE;

EID: 33750960879     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2006-0845     Document Type: Article

References (37)

1. Troiano RP, Flegal KM, Kuczmarski RJ, Campbell SM, Johnson CL. Overweight prevalence in trends for children and adolescents: the National Health and Nutrition Examination Surveys, 1963-1991. Arch Pediatr Adolesc Med. 1995;149:1085-1091
2. del Rio-Navarro BE, Velázquez-Monroy O, Sánchez-Castillo CP, et al. The high prevalence of overweight and obesity in Mexican children. Obes Res. 2004;12:215-223
3. Daniels SR, Arnett DK, Eckel RH, et al. Overweight in children and adolescents: pathoiphysiology, consequences, prevention, and treatment. Circulation. 2005;111:1999-2012
4. Slyper AH. The pediatric obesity epidemic: causes and controversies. J Clin Endocrinol Metab. 2004;89:2540-2547
5. Raitakari OT, Porkka KV, Rönnema T, Akerblom HK. Clustering of risk factors for coronary heart disease in children and adolescents: the Cardiovascular Risk in Young Finns Study. Acta Paediatr. 1994;83:935-940
6. Freedman DA, Dietz WH, Srinivasan SR, Berenson GS. The relation of cardiovascular of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa Heart Study. Pediatrics. 1999;103:1175-1182
7. Dietz WH. Overweight and precursors of type 2 diabetes mellitus in children and adolescents. J Pediatr. 2001;138:453-454
8. Goran MI, Bergman RN, Avila Q, et al. Impaired glucose tolerance and reduced β-cell function in overweight Latino children with a positive family history for type 2 diabetes. J Clin Endocrinol Metab. 2004;89:207-212
9. Wilson DM, Wang Y, Cullen KW, et al. Assessing weight-related biochemical cardiovascular risk factors in African-American girls. Obes Res. 2004;12:73S-83S
10. Raitakari OT, Porkka KV, Ronnemaa T, et al. The role of insulin in clustering of serum lipids and blood pressure in children and adolescents. The Cardiovascular Risk in Young Finns study. Diabetologia. 1995;38:1042-1050
11. Cruz ML, Bergman RN, Goran MI. Unique effect of visceral fat on insulin sensitivity in obese Hispanic children with a family history of type 2 diabetes. Diabetes Care. 2002;25:1631-1636
12. Fujimoto WY, Leonetti DL, Newell-Moris L, Shuman WP, Wahl PW. Relationship of absence or presence of a family history of diabetes to body weight and body fat distribution in type 2 diabetes. Int J Obes (Lond). 1991;15:111-120
13. Rodŕguez-Morán M, Guerrero-Romero F. The parental phenotype of diabetes, but not of essential hypertension, is linked to the development of metabolic syndrome in Mexican individuals. Acta Diabetologica. 2001;38:87-91
14. Guerrero-Romero F, Rodríguez-Morán M, González-Ortiz M, Martínez-Abundis E. Insulin action and secretion in healthy Hispanic-Mexican first-degree relatives of subjects with type 2 diabetes. J Endocrinol Invest. 2001;24:580-586
15. Ferrannini E, Natali A, Bell P, Cavallo-Perai P, Lalic N, Miagrone G. Insulin resistance and hypersecretion in obesity. J Clin Invest. 1997;100:1166-1173
16. Hollenbeck C, Reaven GM. Variations in insulin-stimulated glucose uptake in healthy individuals with normal glucose tolerance. J Clin Endocrinol Metab. 1987;64:1169-1173
17. Cruz ML, Weigensberg MJ, Huang T-K, Ball G, Shaibi GQ, Goran MI. The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivity. J Clin Endocrinol Metab. 2004;89:108-113
18. Haffner SM, Stern MP, Miettinen H, Gingerich R, Bowsher RR. Higher proinsulin and specific insulin are both associated with parental history of diabetes. Diabetes. 1995;44:1156-1160
19. Bao W, Srinivasan SR, Wattigney WA, Berenson GS. The relation of parental cardiovascular disease to risk factors in children and young adults: the Bogalusa Heart Study. Circulation. 1995;91:365-371
20. Chen W, Srinivasan SR, Elkasabany A, Berenson GS. Cardiovascular risk factors clustering features of insulin resistance syndrome (syndrome X) in a biracial (black-white) population of children, adolescents, and young adults: the Bogalusa Heart Study. Am J Epidemiol. 1999;150:667-674
21. Chen W, Srinivasan SR, Elkasabany A, Berenson GS. The association of cardiovascular risk factor clustering related to insulin resistance syndrome (Syndrome X) between young parents and their offspring: the Bogalusa Heart Study. Atherosclerosis. 1999;145:197-205
22. Tanner JM, Whitehouse RH, Takaishi M. Standards from birth to maturity for height, weight, height and weight velocity: British children, 1965. Arch Dis Child. 1996;41:454-495
23. Expert Committee on the diagnosis and classification of diabetes mellitus. Position statements: diagnosis and classification of diabetes mellitus. Diabetes Care. 2004;27:S5-S10
24. The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure [published correction appears in Arch Intern Med. 1998; 158:573]. Arch Intern Med. 1997;157:2413-2446
25. Maffeis C, Pietrobelli A, Grezzani A, Provera S, Tatò L. Waist circumference and cardiovascular risk factors in prepubertal children. Obes Res. 2001;9:179-187
26. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000;320:1240-1245
27. National Cholesterol Education Panel. Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents. NIH Publication 91-2732 Bethesda, MD: National Institutes of Health; 1991
28. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-419
29. Matsumoto K, Sakamaki H, Izumino K, et al. Increased insulin sensitivity and decreased insulin secretion in offspring of insulin-sensitive type 2 diabetic patients. Metabolism. 2000;49:1219-1223
30. Vaag A, Lehtovirta M, Thye-Ronn P, Groop L; European Group of Insulin Resistance. Metabolic impact of a family history of type 2 diabetes: results from a European multicentre study (EGIR). Diabet Med. 2001;18:533-540
31. Arslanian SA, Bacha F, Saad R, Gungor N. Family history of type 2 diabetes is associated with decreased insulin sensitivity and an impaired balance between insulin sensitivity and insulin secretion in white youth. Diabetes Care. 2005;28:115-119
32. Cisneros-Tapia R, Navarrete FA, Gallegos AC, Robles-Sardin AE, Méndez RO, Valencia ME. Insulin sensitivity and associated risk factors in Mexican children and adolescents. Diabetes Care. 2005;28:2546-2547
33. Ebbeling CB, Pawlak DB, Ludwig DS. Chilhood obesity: public health crisis, common sense cure. Lancet. 2002;360:473-482
34. Rodríguez-Morán M, Salazar-Vázquez B, Violante R, Guerrero-Romero F. Metabolic Syndrome among children and adolescents aged 10 to 18 years. Diabetes Care. 2004;27:2516-2517
35. Invitti C, Guzzaloni G, Gilardini L, Morabito F, Viberti G. Prevalence and concomitants of glucose intolerance in European obese children and adolescents. Diabetes Care. 2003;26:118-124
36. Sinha R, Fisch G, Teague B, et al. Prevalence of impaired glucose tolerance among children and adolescents with marked obesity. N Engl J Med. 2002;346:802-810
37. Whitaker RC, Pepe MS, Wright JA, Seidel KD, Dietz WH. Early adiposity rebound and the risk of adult obesity. Pediatrics. 1998; 101(3). Available at:www.pediatrics.org/cgi/content/full/101/3/e5