Conservation and expression of a novel alternatively spliced Evi1 exon

Gene

Volumn 384, Issue 1-2, 2006, Pages 154-162

  Alzuherri, Hadi ^a   McGilvray, Roger ^a   Kilbey, Anna ^a   Bartholomew, Chris ^a  

^a GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

Author keywords

Alternative gene splicing; Development; Evi1; Leukaemia

Indexed keywords

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; EVI1 GENE; EXON; GENE; GENE EXPRESSION; GENETIC CONSERVATION; GENETIC ORGANIZATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOLECULAR EVOLUTION; PRIORITY JOURNAL; PROTEIN DOMAIN; VERTEBRATE;

ALTERNATIVE SPLICING; ANIMALS; DNA-BINDING PROTEINS; EXONS; GENE DELETION; GENE EXPRESSION REGULATION; HUMANS; MICE; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENES; RNA SPLICING; TRANSCRIPTION FACTORS; TRANSFORMATION, GENETIC;

MURINAE; VERTEBRATA;

EID: 33750947997     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2006.07.027     Document Type: Article

References (29)

1. Bartholomew C., and Ihle J.N. Retroviral insertions 90 kilobases proximal to the Evi1 myeloid transforming gene activate transcription from the normal promoter. Mol. Cell. Biol. 11 (1991) 1820-1828
2. Bartholomew C., Kilbey A., Clark A.-M., and Walker M. The Evi1 proto-oncogene encodes a transcriptional repressor activity associated with transformation. Oncogene 14 (1997) 569-577
3. Bordereaux D., Fichelson S., Tambourin P., and Gisselbrecht S. Alternative splicing of the Evi1 zinc finger gene generates mRNAs which differ by the number of zinc finger motifs. Oncogene 5 (1990) 925-927
4. Delwel R., Funabiki T., Kreider B.L., Morishita K., and Ihle J.N. Four of the seven zinc fingers of the Evi1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA. Mol. Cell. Biol. 13 (1993) 4291-4300
5. Fears S., Mathieu C., Zeleznik-Le N., Huang S., Rowley J.D., and Nucifora G. Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukaemia and produces a new member of the PR domain family. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 1642-1647
6. Funabiki T., Kreider B.L., and Ihle J.N. The carboxyl domain of zinc fingers of the Evi1 myeloid transforming gene binds a consensus sequence of GAAGATGAG. Oncogene 9 (1994) 1575-1581
7. Garriga G., Guenther C., and Horvitz H.R. Migrations of the Caenorhabditis elegans HSNs are regulated by egl-43, a gene encoding two zinc finger proteins. Genes Dev. 7 (1993) 2097-2109
8. Hoyt P.R., et al. The Evi1 proto-oncogene is required at midgestation for neural, heart and paraxial mesenchyme development. Mech. Dev. 65 (1997) 55-70
9. Huang S. The retinoblastoma protein-interacting zinc finger gene RIZ in 1p36-linked cancers. Front. Biosci. 4 (1999) d528-d532
10. Kazama H., Kodera T., Shimizu S., Mizoguchi H., and Morishita K. Ecotropic viral integration site-1 is activated during, and is sufficient for, neuroectodermal P19 cell differentiation. Cell Growth Differ. 10 (1999) 565-573
11. Kilbey A., and Bartholomew C. Evi1 ZF1 DNA binding activity and a second distinct transcriptional repressor region are both required for optimal transformation of Rat1 fibroblasts. Oncogene 16 (1998) 2287-2291
12. Mead P.E., et al. Evi1 expression in Xenopus. Gene Expr. Patterns 5 (2005) 601-608
13. Modrek B., and Lee C. A genomic view of alternative splicing. Nat. Genet. 30 (2002) 13-19
14. Modrek B., and Lee C. Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat. Genet. 34 (2003) 177-180
15. Moore A.W., Jan L.Y., and Jan Y.N. hamlet, a binary genetic switch between single- and multiple-dendrite neuron morphology. Science 297 (2002) 1355-1358
16. Morishita K., Parganas E., Douglass E.C., and Ihle J.N. Unique expression of the human EVI1 gene in an endometrial carcinoma cell line: sequence of cDNAs and structure of alternatively spliced transcripts. Oncogene 5 (1990) 963-971
17. Morishita K., Parker D.S., Mucenski M.L., Jenkins N.A., Copeland N.G., and Ihle J.N. Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukaemia cell lines. Cell 54 (1988) 831-840
18. Morishita K., Parganas E., Matsugi T., and Ihle J.N. Expression of the Evi1 zinc finger gene in 32Dcl3 myeloid cells blocks granulocyte differentiation in response to granulocyte colony-stimulating factor. Mol. Cell. Biol. 12 (1992) 183-189
19. Morishita K., et al. Activation of EVI1 gene expression in human acute myelogenous leukaemias by translocations spanning 300-400 kilobases on chromosome band 3q26. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 3937-3941
20. 1-28 CTCATCTTC. Oncogene 10 (1995) 1961-1967
21. Nurtdinov R.N., Artamonova I.I., Mironov A.A., and Gelfand M.S. Low conservation of alternative splicing patterns in the human and mouse genomes. Hum. Mol. Genet 12 (2003) 1313-1320
22. Palmer S., et al. Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins. J. Biol. Chem. 276 (2001) 25834-25840
23. Resch A., Xing Y., Modrek B., Gorlick M., Riley R., and Lee C. Assessing the impact of alternative splicing on domain interactions in the human proteome. J. Proteome Res. 3 (2004) 76-83
24. Sadowski I., and Ptashne M. A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res. 17 (1989) 7539
25. Soderholm J., Kobayashi H., Mathieu C., Rowley J.D., and Nucifora G. The leukaemia-associated gene MDS1/EVI1 is a new type of GATA-binding transactivator. Leukaemia 11 (1997) 352-358
26. Suzukawa K., et al. Identification of translocational breakpoints within the intron region before the last coding exon (exon 12) of the EVI1 gene in two cases of CML-BC with inv(3)(q21q26). Genomics 42 (1997) 356-360
27. Van Campenhout C., et al. Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formation. Dev. Biol. 294 (2006) 203-219
28. Wimmer K., Vinatzer U., Zwirn P., Fonatsch C., and Wieser R. Comparative expression analysis of the antagonistic transcription factors EVI1 and MDS1-EVI1 in murine tissues and during in vitro haemopoietic differentiation. Biochem. Biophys. Res. Comm. 252 (1998) 691-696
29. Xing Y., Xu Q., and Lee C. Widespread production of novel soluble protein isoforms by alternative splicing removal of transmembrane anchoring domains. FEBS Lett. 555 (2003) 572-578