Difference gel electrophoresis DIGE

Drug Discovery Today: Technologies

Volumn 3, Issue 3, 2006, Pages 347-353

  Lilley, Kathryn S ^a   Friedman, David B ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Mass Spectrometry Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE;

CLUSTER ANALYSIS; COMPUTER PROGRAM; DIFFERENCE GEL ELECTROPHORESIS; DIFFERENTIAL DISPLAY; DRUG TARGETING; FALSE POSITIVE RESULT; GEL ELECTROPHORESIS; HYDROPHOBICITY; ISOELECTRIC POINT; LASER CAPTURE MICRODISSECTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR WEIGHT; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN TARGETING; PROTEOMICS; QUANTITATIVE ASSAY; REVIEW; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

EID: 33750939786     PISSN: 17406749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddtec.2006.09.013     Document Type: Review

References (41)

1. Petricoin E.F., and Liotta L.A. SELDI-TOF-based serum proteomic pattern diagnostics for early detection of cancer. Curr. Opin. Biotechnol. 15 (2004) 24-30
2. Unlu M., et al. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis 18 (1997) 2071-2077
3. Karp N.A., et al. Impact of replicate types on proteomic expression analysis. J. Proteome Res. 4 (2005) 1867-1871
4. Fodor I.K., et al. Statistical challenges in the analysis of two-dimensional difference gel electrophoresis experiments using DeCyder. Bioinformatics 21 (2005) 3733-3740 Epub 2005 Aug 9
5. Friedman D.B., et al. Proteome analysis of human colon cancer by two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics 4 (2004) 793-811
6. Kondo T., et al. Application of sensitive fluorescent dyes in linkage of laser microdissection and two-dimensional gel electrophoresis as a cancer proteomic study tool. Proteomics 3 (2003) 1758-1766
7. Gygi S.P., et al. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat. Biotechnol. 17 (1999) 994-999
8. Ross P.L., et al. Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol. Cell Proteomics 3 (2004) 1154-1169 Epub 2004 Sep 22
9. Old W.M., et al. Comparison of label-free methods for quantifying human proteins by shotgun proteomics. Mol. Cell Proteomics 4 (2005) 1487-1502 Epub 2005 Jun 23
10. Fujii K., et al. Toward a comprehensive quantitative proteome database: protein expression map of lymphoid neoplasms by 2-D DIGE and MS. Proteomics 3 (2006) 3
11. Fujii K., et al. Protein expression pattern distinguishes different lymphoid neoplasms. Proteomics 5 (2005) 4274-4286
12. Karp N.A., et al. Application of partial least squares discriminant analysis to two-dimensional difference gel studies in expression proteomics. Proteomics 5 (2005) 81-90
13. Seike M., et al. Proteomic signature of human cancer cells. Proteomics 4 (2004) 2776-2788
14. Verhoeckx K.C., et al. In search of secreted protein biomarkers for the anti-inflammatory effect of beta2-adrenergic receptor agonists: application of DIGE technology in combination with multivariate and univariate data analysis tools. J. Proteome Res. 4 (2005) 2015-2023
15. Suehara Y., et al. Proteomic signatures corresponding to histological classification and grading of soft-tissue sarcomas. Proteomics 6 (2006) 4402-4409
16. Apraiz I., et al. Identification of Proteomic Signatures of Exposure to Marine Pollutants in Mussels (Mytilus edulis). Mol. Cell Proteomics 5 (2006) 1274-1285 Epub 2006 Apr 7
17. Friedman D.B., et al. Staphylococcus aureus Redirects Central Metabolism to Increase Iron Availability. PLoS Pathogens 2 (2006) e87
18. Gade D., et al. Evaluation of Two-Dimensional Difference Gel Electrophoresis for Protein Profiling. Soluble Proteins of the Marine Bacterium PIRELLULA sp. Strain 1. J. Mol. Microbiol. Biotechnol. 5 (2003) 240-251
19. Lee I.N., et al. Identification of human hepatocellular carcinoma-related biomarkers by two-dimensional difference gel electrophoresis and mass spectrometry. J. Proteome Res. 4 (2005) 2062-2069
20. Liang C.R., et al. Proteome analysis of human hepatocellular carcinoma tissues by two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics 5 (2005) 2258-2271
21. Nabetani T., et al. Proteomic analysis of livers of patients with primary hepatolithiasis. Proteomics 5 (2005) 1043-1061
22. Huang H.L., et al. Biomarker discovery in breast cancer serum using 2-D differential gel electrophoresis/MALDI-TOF/TOF and data validation by routine clinical assays. Electrophoresis 27 (2006) 1641-1650
23. Somiari R.I., et al. High-throughput proteomic analysis of human infiltrating ductal carcinoma of the breast. Proteomics 3 (2003) 1863-1873
24. Nishimori T., et al. Proteomic analysis of primary esophageal squamous cell carcinoma reveals downregulation of a cell adhesion protein, periplakin. Proteomics 6 (2006) 1011-1018
25. Zhou G., et al. 2D differential in-gel electrophoresis for the identification of esophageal scans cell cancer-specific protein markers. Mol. Cell Proteomics 1 (2002) 117-124
26. Yu K.H., et al. Characterization of proteins in human pancreatic cancer serum using differential gel electrophoresis and tandem mass spectrometry. J. Proteome Res. 4 (2005) 1742-1751
27. Wan J., et al. Inflammation inhibitors were remarkably up-regulated in plasma of severe acute respiratory syndrome patients at progressive phase. Proteomics 6 (2006) 2886-2894
28. Greengauz-Roberts O., et al. Saturation labeling with cysteine-reactive cyanine fluorescent dyes provides increased sensitivity for protein expression profiling of laser-microdissected clinical specimens. Proteomics 5 (2005) 1746-1757
29. Sitek B., et al. Application of fluorescence difference gel electrophoresis saturation labelling for the analysis of microdissected precursor lesions of pancreatic ductal adenocarcinoma. Proteomics 5 (2005) 2665-2679
30. Sitek B., et al. Novel approaches to analyse glomerular proteins from smallest scale murine and human samples using DIGE saturation labelling. Proteomics 3 (2006) 3
31. Hu Y., et al. Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid. Mol. Cell Proteomics 4 (2005) 2000-2009 Epub 2005 Sep 30
32. Tetu B., et al. Prognostic influence of HSP-27 expression in malignant fibrous histiocytoma: a clinicopathological and immunohistochemical study. Cancer Res. 52 (1992) 2325-2328
33. Keshamouni V.G., et al. Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype. J. Proteome Res. 5 (2006) 1143-1154
34. Krijgsveld J., et al. Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics. Nat. Biotechnol. 21 (2003) 927-931
35. Ong S., et al. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol. Cell Proteomics 1 (2002) 376-386
36. Silva J.C., et al. Simultaneous qualitative and quantitative analysis of the Escherichia coli proteome: a sweet tale. Mol. Cell Proteomics 5 (2006) 589-607 Epub 2006 Jan 5
37. Gorg A., et al. The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 21 (2000) 1037-1053
38. Lee K., et al. A more practical strategy for interfacing microscale solution phase IEF with commercially available very narrow range IPG strips for optimal protein separation. Electrophoresis 5 (2006) 5
39. Zuo X., and Speicher D.W. Comprehensive analysis of complex proteomes using microscale solution isoelectrofocusing prior to narrow pH range two-dimensional electrophoresis. Proteomics 2 (2002) 58-68
40. Link A.J., et al. Direct analysis of protein complexes using mass spectrometry. Nat. Biotechnol. 17 (1999) 676-682
41. Washburn M.P., et al. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol. 19 (2001) 242-247