In search of secreted protein biomarkers for the anti-inflammatory effect of β2-adrenergic receptor agonists: Application of DIGE technology in combination with multivariate and univariate data analysis tools

Journal of Proteome Research

Volumn 4, Issue 6, 2005, Pages 2015-2023

  Verhoeckx, Kitty C M ^a,b   Gaspari, Marco ^a   Bijlsma, Sabina ^a   Van Der Greef, Jan ^a,b   Witkamp, Renger F ^a   Doornbos, Robert P ^a   Rodenburg, Richard J T ^c  

^a TNO   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

2 adrenergic receptor; Difference gel electrophoresis; Macrophage inflammatory protein 1 ; Multivariate data analysis; Partial least squares discriminant analysis; Principal component analysis; Zilpaterol

Indexed keywords

ADENYLATE KINASE; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BIOLOGICAL MARKER; BUTYRYL CYCLIC AMP; CLENBUTEROL; ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; FORMOTEROL; FORSKOLIN; HEAT SHOCK PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PHOSPHOGLYCERATE MUTASE; PROPRANOLOL; PROSTAGLANDIN E2; PROTEOME; SALBUTAMOL; UNCLASSIFIED DRUG; ZILPATEROL;

ADRENERGIC SYSTEM; ANALYTIC METHOD; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DISCRIMINANT ANALYSIS; HUMAN; HUMAN CELL; INFLAMMATION; LIQUID CHROMATOGRAPHY; MACROPHAGE; MASS SPECTROMETRY; MULTIVARIATE ANALYSIS; NUCLEOTIDE SEQUENCE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEOMICS; STATISTICAL ANALYSIS; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ADRENERGIC AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL MARKERS; CLUSTER ANALYSIS; DOWN-REGULATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOASSAY; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGE INFLAMMATORY PROTEIN-1; MACROPHAGES; MASS SPECTROMETRY; MONOCYTES; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; PROPRANOLOL; PROTEOME; PROTEOMICS; RECEPTORS, ADRENERGIC, BETA-2; STATISTICS; TRIMETHYLSILYL COMPOUNDS; U937 CELLS; UP-REGULATION;

ESCHERICHIA COLI;

EID: 29144519818     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr050183u     Document Type: Article

References (56)

1. Heumann, D.; Glauser, M. P. Sci. Am. Sci. Med. 1994, 28-37.
2. Cirino, G. Biochem. Pharmacol. 1998, 55 (2), 105-111.
3. Henderson, B.; Poole, S.; Wilson, M. Microbiol. Rev. 1996, 60 (2), 316-341.
4. Lotvall, J. Pulm. Pharmacol. Ther. 2002, 15 (6), 497-501.
5. Libretto, S. E. Arch. Toxicol. 1994, 68 (4), 213-216.
6. Barnes, P. J. J. Allergy Clin, Immunol. 1999, 104 (2 Pt 2), S10-17.
7. Liggett, S. B. J. Allergy Clin. Immunol. 2002, 110 (6 Suppl), S223-227.
8. Strosberg, A. D. Protein Sci. 1993, 2 (8), 1198-1209.
9. Lombardi, M. S.; Kavelaars, A.; Heijnen, C. J. Crit. Rev. Immunol. 2002, 22 (2), 141-163.
10. Ji, T. H.; Grossmann, M.; Ji, I. J. Biol. Chem. 1998,273 (28), 17299-17302.
11. Nurnberg, B.; Gudermann, T.; Schultz, G. J. Mol. Med. 1995, 73 (3), 123-132.
12. Neer, E. J. Protein Sci. 1994, 3 (1), 3-14.
13. Zidek, Z. Eur. Cytokine Netw. 1999, 10 (3), 319-328.
14. Sekut, L.; Champion, B. R.; Page, K.; Menius, J. A., Jr.; Connolly, K. M. Clin. Exp. Immunol. 1995, 99 (3), 461-466.
15. Izeboud, C. A.; Mocking, J. A.; Monshouwer, M.; van Miert, A. S.; Witkamp, R. F. J. Recept. Signal Transduction Res. 1999, 19 (1-4), 191-202.
16. Izeboud, C. A.; Vermeulen, R. M.; Zwart, A.; Voss, H. P.; van Miert, A. S.; Witkamp, R. F. Naunyn Schmiedebergs Arch. Pharmacol. 2000, 362 (2), 184-9.
17. Izeboud, C. A.; Monshouwer, M.; van Miert, A. S.; Witkamp, R. F. Inflamm. Res. 1999, 48 (9), 497-502.
18. Verhoeckx, K. C.; Bijlsma, S.; Jespersen, S.; Ramaker, R.; Verheij, E. R.; Witkamp, R. F.; Van Der Greef, J.; Rodenburg, R. J. Int. Immunopharmacol. 2004, 4 (12), 1499-1514.
19. Zilpaterol technical brochure, Intervet. 1998.
20. Alban, A.; David, S. O.; Bjorkesten, L.; Andersson, C.; Sloge, E.; Lewis, S.; Currie, I. Proteomics 2003, 3 (1), 36-44.
21. Unlu, M.; Morgan, M. E.; Minden, J. S. Electrophoresis 1997, 18 (11), 2071-2077.
22. Tonge, R.; Shaw, J.; Middleton, B.; Rowlinson, R.; Rayner, S.; Young, J.; Pognan, F.; Hawkins, E.; Currie, I.; Davison, M. Proteomics 2001, 1 (3), 377-396.
23. Massart, D. L.; Vandeginste, B. G. M.; De Jong, P. J. Handbook of chemometrics and Qualimetrics, Part A; Elsevier: Amsterdam, The Netherlands, 1997; Vol. p.
24. Vandeginste, B. G. M.; Massart, D. L.; Buydens, L. M. C.; De Jong, P. J. Handbook of Chemometrics and Qualimetrics: Part B; Elsevier: Amsterdam, The Netherlands, 1998.
25. Dillon, W. R.; Goldstein, M. Multivariate Analysis: Methods and Applications; John Wiley & Sons Inc.: New York, U.S.A., 1984.
26. Joliffe, I. T. Principal Component Analysis; Springer-Verlag: New York, U.S.A., 1986.
27. Martens, H.; Naes, T. Multivariate Calibrations, 1st ed.; John Wiley & Sons: Chichester, England, 1992.
28. Barker, M.; Rayens, W. J. Chemometrics 2003, 17, 166-173.
29. Sundstrom, C.; Nilsson, K. Int. J. Cancer 1976, 17 (5), 565-577.
30. Verhoeckx, K. C.; Bijlsma, S.; de Groene, E. M.; Witkamp, R. F.; van der Greef, J.; Rodenburg, R. J. Proteomics 2004, 4 (4), 1014-1028.
31. Kreutz, M.; Krause, S. W.; Hennemann, B.; Rehm, A.; Andreesen, R. Res. Immunol. 1992, 143 (1), 107-115.
32. Verhoeckx, K. C. M.; Doorenbos, R. P.; Witkamp, R. F.; Van der Greef, J.; Rodenburg, R. J. Int. Immunopharmacol. 2005, in press.
33. Kleno, T. G.; Leonardsen, L. R.; Kjeldahl, H. O.; Laursen, S. M.; Jensen, O. N.; Baunsgaard, D. Proteomics 2004, 4 (3), 868-880.
34. Karp, N. A.; Griffin, J. L.; Lilley, K. S. Proteomics 2005, 5 (1), 81-90.
35. Rabilloud, T.; Strub, J. M.; Luche, S.; van Dorsselaer, A.; Lunardi, J. Proteomics 2001, 1 (5), 699-704.
36. Rabilloud, T.; Strub, J. M.; Luche, S.; Girardet, J. L.; van Dorselaer, A.; Lundardi, J. Ruthenium II tris (bathophenanthroline disulfonate), a powerfull fluorescent stain for detection of proteins in gel with minimal interference in subsequent mass spectrometry analysis, http://link.springer.de/ link/service/journals/10216/ contents/00/00002/ (30 august).
37. Gorg, A.; Weiss, W.; Dunn, M. J. Proteomics 2004, 4 (12), 3665-3685.
38. Rabilloud, T. Proteomics 2002, 2 (1), 3-10.
39. Shaw, J.; Rowlinson, R.; Nickson, J.; Stone, T.; Sweet, A.; Williams, K.; Tonge, R. Proteomics 2003, 3 (7), 1181-95.
40. Katayama, H.; Nagasu, T.; Oda, Y. Rapid Commun. Mass Spectrom. 2001, 15 (16), 1416-1421.
41. Soskic, V.; Godovac-Zimmermann, J. Proteomics 2001, 1 (11), 1364-1367.
42. Zischka, H.; Gloeckner, C. J.; Klein, C.; Willmann, S.; Swiatek-de Lange, M.; Ueffing, M. Proteomics 2004, 4 (12), 3776-3782.
43. Nomura, E.; Katsuta, K.; Ueda, T.; Toriyama, M.; Mori, T.; Inagaki, N. J. Mass Spectrom. 2004, 39 (2), 202-207.
44. Katayama, H.; Tabata, T.; Ishihama, Y.; Sato, T.; Oda, Y.; Nagasu, T. Rapid Commun. Mass Spectrom. 2004, 18 (20), 2388-2394.
45. Lui, M.; Tempst, P.; Erdjument-Bromage, H. Anal. Biochem. 1996, 241 (2), 156-166.
46. Jessen, F.; Lametsch, R.; Bendixen, E.; Kjaersgard, I. V.; Jorgensen, B. M. Proteomics 2002, 2 (1), 32-35.
47. Watt, S. A.; Wilke, A.; Patschkowski, T.; Niehaus, K. Proteomics 2005, 5 (1), 153-167.
48. Kubota, K.; Wakabayashi, K.; Matsuoka, T. Proteomics 2003, 3 (5), 616-626.
49. Dupont, A.; Tokarski, C.; Dekeyzer, O.; Guihot, A. L.; Amouyel, P.; Rolando, C.; Pinet, F. Proteomics 2004, 4 (6), 1761-1778.
50. Kast, R. E. Int. J. Immunopharmacol. 2000, 22 (11), 1001-1006.
51. Martin, C. A.; Dorf, M. E. Cell. Immunol. 1991,135 (1), 245-258.
52. Menten, P.; Wuyts, A.; Van Damme, J. Cytokine Growth Factor Rev. 2002, 13 (6), 455-481.
53. Schall, T. J.; Bacon, K.; Camp, R. D.; Kaspari, J. W.; Goeddel, D. V. J. Exp. Med. 1993, 177 (6), 1821-1826.
54. O'Grady, N. P.; Tropea, M.; Preas, H. L., 2nd; Reda, D.; Vandivier, R. W.; Banks, S. M.; Suffredini, A. F. J. Infect. Dis. 1999, 179 (1), 136-141.
55. Li, C. Y.; Chou, T. C.; Lee, C. H.; Tsai, C. S.; Loh, S. H.; Wong, C. S. Anesth. Analg. 2003, 96 (2), 518-523.
56. Hasko, G.; Shanley, T. P.; Egnaczyk, G.; Nemeth, Z. H.; Salzman, A. L.; Vizi, E. S.; Szabo, C. Br. J. Pharmacol. 1998, 125 (6), 1297-1303.