The effect of antibodies to TGF-β1 and TGF-β2 at a site of sciatic nerve repair

Journal of the Peripheral Nervous System

Volumn 11, Issue 4, 2006, Pages 286-293

  Atkins, Simon ^a   Smith, Keith G ^a   Loescher, Alison R ^a   Boissonade, Fiona M ^a   Ferguson, Mark W J ^b   Robinson, Peter P ^a,c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Nerve regeneration; Nerve repair; Scarring; Sciatic nerve; Transforming growth factor

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; GENERAL ANESTHESIA; IMMUNOHISTOCHEMISTRY; MALE; MYELINATION; NERVE FIBER DEGENERATION; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SCAR FORMATION; SCIATIC NERVE; SCIATIC NEUROPATHY; TREATMENT OUTCOME;

ACTION POTENTIALS; ANIMALS; ANTIBODIES; AXOTOMY; CICATRIX; MALE; NERVE REGENERATION; NEUROMA; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

EID: 33750924978     PISSN: 10859489     EISSN: 15298027     Source Type: Journal    
DOI: 10.1111/j.1529-8027.2006.00100.x     Document Type: Article

References (50)

1. Adanali G, Verdi M, Tuncel A, Erdogan B, Kargi E (2003). Effects of hyaluronic acid-carboxymethylcellulose membrane on extraneural adhesion formation and peripheral nerve regeneration. J Reconstr Microsurg 19:29-36.
2. Amir R, Devor M (1993). Ongoing activity in neuroma afferents bearing retrograde sprouts. Brain Res 630:283-288.
3. Ashur H, Vilner Y, Finsterbush A, Weinburg H, Devor M (1987). Extent of fibre regeneration after peripheral nerve repair: silicone splint v suture, gap repair v graft. Exp Neurol 97:365-374.
4. Bradbury EJ, Moon LD, Popat RJ, King VR, Bennett GS, Patel PN, Fawcett JW, McMahon SB (2002). Chondroitinase ABC promotes functional recovery after spinal nerve injury. Nature 416:589-590.
5. Bucko CD, Joynt RL, Grabb WC (1981). Peripheral nerve regeneration in primates during D-penicillamine-induced lathyrism. Plast Reconstr Surg 67:23-31.
6. Chalazonitis A, Kalberg J, Twardzik DR, Morrison RS, Kessler JA (1992). Transforming growth factor b has neurotrophic actions on sensory neurons in vitro and is synergistic with nerve growth factor. Dev Biol 152:121-132.
7. Davison SP, McCaffrey TV, Porter MN, Manders E (1999). Improved nerve regeneration with neutralisation of transforming growth factor-beta 1. Laryngoscope 109:631-635.
8. Devor M (2001). Neuropathic pain: what do we do with all these theories? Acta Anaesthesiol Scand 45:1121-1127.
9. Devor M, Seltzer Z (1999). Pathophysiology of Damaged Nerves in Relation to Chronic Pain. In: Textbook of Pain. Wall PD, Melzack R (Eds). Churchill Livingstone, London, pp 129-164.
10. Einheber S, Hannocks M-J, Metz CN, Rifkin DB (1995). Transforming growth factor-β1 regulates axon/Schwann cell interactions. J Cell Biol 129:443-458.
11. Ferguson MWJ, O'Kane S (2004). Scar-free healing: from embryonic mechanisms to adult therapeutic intervention. Phil Trans R Soc Lond B 359:839-850.
12. Gordon T, Sulaiman O, Boyd JG (2003). Experimental strategies to promote functional recovery after peripheral nerve injuries. J Peripher Nerv Syst 8:236-250.
13. Gorgulu A, Uzal C, Doganay L, Imer M, Eliuz K, Cobanoglu S (2003). The effect of low-dose external beam radiation on extraneural scarring after peripheral nerve surgery in rats. Neurosurgery 53:1389-1395.
14. Graham W, Patakey P, Calabretta A, Munger B, Buda M (1973). Enhancement of peripheral nerve regeneration with triamcinolone after neurorrhaphy. Surg Forum 24:457-461.
15. Guenard V, Gwynn LA, Wood PM (1995). Transforming growth factor-beta blocks myelination but not ensheathment of axons by Schwann cells in vitro. J Neurosci 15:419-428.
16. Jiang Y, McLennan IS, Koishi K, Hendry IA (2000). Transforming growth factor-beta 2 is anterogradely and retrogradely transported in motoneurons and up-regulated after injury. Neuroscience 97:735-742.
17. Junqueira LCU, Bignolas G, Brentani RR (1979). Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 11:447-455.
18. Karanas YL, Bogdan MA, Lineaweaver WC, Hentz VR, Longaker MT, Chang J (2001). Gene expression of transforming growth factor beta isoforms in interposition nerve grafting. J Hand Surg 26:1082-1087.
19. King VR, Phillips JB, Brown RA, Priestly JV (2004). The effects of treatment with antibodies to transforming growth factor beta1 and beta2 following spinal cord damage in the adult rat. Neuroscience 126:173-183.
20. Lane JM, Bora FW, Pleasure D (1978). Neuroma scar formation in rats following peripheral nerve transection. J Bone Joint Surg Am 60:197-203.
21. Logan A, Berry M, Gonzalez AM, Frautschy SA, Sporn MB, Baird A (1994). Effects of transforming growth factor beta 1 on scar production in the central nervous system of the rat. Eur J Neurosci 6:355-363.
22. Logan A, Green J, Hunter A, Jackson R, Berry M (1999). Inhibition of glial scarring in the injured rat brain by a recombinant human monoclonal antibody to transforming growth factor-beta2. Eur J Neurosci 11:2367-2374.
23. Mathur A, Merrell JC, Russell RC, Zook EG (1983). A scanning electron microscopy evaluation of peripheral nerve regeneration. Scan Electron Microsc 2:975-981.
24. Matsuoka I, Nakane A, Kurihara K (1997). Induction of LIF-mRNA by TGF-beta1 in Schwann cells. Brain Res 776:170-180.
25. Mayhew TM (1990). Efficient and Unbiased Sampling of Nerve Fibres for Estimating Fiber Number and Size. In: Quantitative and Qualitative Microscopy. Conn PM (Ed). Academic Press, London, pp 172-187.
26. McCallion RL, Ferguson MWJ (1996). Fetal Wound Healing and the Development of Antiscarring Therapies for Adult Wound Healing. In: The Molecular and Cell Biology of Wound Repair, 2nd edn. Clark RAF (Ed). Plenum Press, New York, pp 561-599.
27. Nachemson AK, Lundborg G, Myrhage R, Rank F (1985). Nerve regeneration after pharmacological suppression of the scar reaction at the suture site. An experimental study on the effect of estrogen-progesterone, methylprednisolone- acetate and cis-hydroxyproline in rat sciatic nerve. Scand J Plast Reconstr Surg 19:255-260.
28. Nath RK, Kwon B, Mackinnon SE, Jensen JN, Reznik S, Boutros S (1998). Antibody to transforming growth factor beta reduces collagen production in injured peripheral nerve. Plast Reconstr Surg 102:1100-1108.
29. O'Kane S, Ferguson MWJ (1997). Transforming growth factor bs and wound healing. Int J Biochem Cell Biol 29:63-78.
30. Ozgenel GY (2003). Effects of hyaluronic acid on peripheral nerve scarring and regeneration in rats. Microsurgery 23:575-581.
31. Ozgenel GY, Filiz G (2003). Effects of human amniotic fluid on peripheral nerve scarring and regeneration in rats. J Neurosurg 98:371-377.
32. Ozgenel GY, Filiz G (2004). Combined application of human amniotic membrane wrapping and hyaluronic acid injection in epineurectomised rat sciatic nerve. J Reconstr Surg 20:153-157.
33. Peterson J, Russell L, Andrus K, Mackinnon M, Silver J, Kliot M (1996). Reduction of extraneural scarring by ADCON-T/N after surgical intervention. Neurosurgery 38:976-983.
34. Robinson PP, Loescher AR, Smith KG (2000). A prospective, quantitative study on the clinical outcome of lingual nerve repair. Br J Oral Maxillofac Surg 38:255-263.
35. Rogister B, Delree P, Leprince P, Martin D, Sadzot C, Malgrange B, Munaut C, Rigo JM, Lefebvre PP, Octave JN, Schoenen J, Moonen G (1993). Transforming growth factor beta as a neuronoglial signal during peripheral nervous system response to injury. J Neurosci Res 34:32-43.
36. Rufer M, Flanders K, Unsicker K (1994). Presence and regulation of transforming growth factor beta mRNA and protein in the normal and lesioned rat sciatic nerve. J Neurosci Res 39:412-423.
37. Rydevik M, Bergstrom F, Mitts C, Danielson N (2002). Locally-applied collagenase and regeneration of transected and repaired rat sciatic nerves. Scand J Plast Reconstr Surg Hand Surg 36:193-196.
38. Scherer SS, Kamholz J, Jakowlew S (1993). Axons modulate the expression of transforming growth factor betas in Schwann cells. Glia 8:265-276.
39. Shah M, Foreman DM, Ferguson MJW (1994). Neutralising antibody to TGF-β1, 2 reduces scarring in adult rodents. J Cell Sci 107:1137-1157.
40. Shah M, Foreman DM, Ferguson MJW (1995). Neutralisation of TGF-β1 and TGF-β2 or exogenous addition of TGF-β3 to cutaneous rat wounds reduces scarring. J Cell Sci 108:985-1002.
41. Sunderland S (1978). Nerves and Nerve Injuries, 2nd Edn. Churchill Livingstone, London.
42. Sunderland S, Bradley KC (1959). Endoneurial tube shrinkage in the distal segment of a severed nerve. J Comp Neurol 93:411-420.
43. Taskinen HS, Ruohonen S, Jagodic M, Khademi M, Olsson T, Roytta M (2004). Distinct expression of TGF-beta1 mRNA in the endo- and epineurium after injury. J Neurotrauma 21:969-975.
44. Unsicker K, Strelau J (2000). Functions of transforming growth factor-β isoforms in the nervous system. Eur J Biochem 267:6972-6975.
45. Wahl SM, Hunt DA, Wakefield LM, McCartney-Francis N, Wahl LM, Roberts AB, Sporn MB (1987). Transforming growth factor type b induces monocyte chemotaxis and growth factor production. Proc Natl Acad Sci U S A 84:5788-5792.
46. Wehling P, Pak M, Cleveland S, Nieper R (1992). The influence of bacterial collagenase on regeneration of severed rat sciatic nerves. Acta Neurochir 119:121-127.
47. Williams RS, Rossi AM, Chegini N, Schultz G (1992). Effect of transforming growth factor β on post-operative adhesion formation and intact peritoneum. J Surg Res 52:65-70.
48. Yates JM, Smith KG, Robinson PP (2000). Ectopic neural activity from myelinated afferent fibres in the lingual nerve of the ferret following three types of injury. Brain Res 874:37-47.
49. Yates JM, Smith KG, Robinson PP (2004). The effect of triamcinolone hexacetonide on the spontaneous and mechanically-induced ectopic discharge following lingual nerve injury in the ferret. Pain 111:261-269.
50. Zou T, Ling C, Xiao Y, Tao X, Ma D, Chen ZL, Strickland S, Song H (2006). Exogenous tissue plasminogen activator enhances peripheral nerve regeneration and functional recovery after injury in mice. J Neuropathol Exp Neurol 65:78-86.