-
1
-
-
0029097839
-
Progress with humanized antibodies – an update.
-
Adair, J.R. & Bright, S.M. 1995 Progress with humanized antibodies – an update. Exp. Opin. Invest. Drugs, 4, 863 870.
-
(1995)
Exp. Opin. Invest. Drugs
, vol.4
, pp. 863-870
-
-
Adair, J.R.1
Bright, S.M.2
-
2
-
-
0027569648
-
Effects of transforming growth factor β1 on the extracellular matrix and cytoskeleton of cultured astrocytes.
-
Baghdassarian‐Chalaye, D., Toru‐Delbauffe, D., Gaveret, J.M., Pierre, M. 1993 Effects of transforming growth factor β1 on the extracellular matrix and cytoskeleton of cultured astrocytes. Glia, 7, 193 202.
-
(1993)
Glia
, vol.7
, pp. 193-202
-
-
Baghdassarian‐Chalaye, D.1
Toru‐Delbauffe, D.2
Gaveret, J.M.3
Pierre, M.4
-
3
-
-
0029991439
-
Phase II study of weekly intravenous recombinant humanized anti‐p185HER2 monoclonal antibody in patients with HER2/neu‐overexpressing metastatic breast cancer.
-
Baselga, J., Tripathy, D., Mendelsohn, J., Baughman, S., Benz, C.C., Dantis, L., Sklarin, N.T., Seidman, A.D., Hudis, C.A., Moore, J., Rosen, P.P., Twaddell, T., Henderson, I.C., Norton, L. 1996 Phase II study of weekly intravenous recombinant humanized anti‐p185HER2 monoclonal antibody in patients with HER2/neu‐overexpressing metastatic breast cancer. J. Clin. Oncol., 14, 737 744.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
Rosen, P.P.11
Twaddell, T.12
Henderson, I.C.13
Norton, L.14
-
4
-
-
0028036290
-
Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV‐infected mice.
-
Crowe, J.E., Murphy, B.R., Chanock, R.M., Williamson, R.A., Barbas, C.F. III, Burton, D.R. 1994 Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV‐infected mice. Proc. Natl Acad. Sci. USA, 91, 1386 1390.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 1386-1390
-
-
Crowe, J.E.1
Murphy, B.R.2
Chanock, R.M.3
Williamson, R.A.4
Barbas, C.F.5
Burton, D.R.6
-
5
-
-
77957048521
-
Transforming growth factor βs: Biochemistry and biological activities in vivo and in vitro, in: Growth Factors in Health and Disease
-
Cui, W. & Ackhurst, R.J. 1996 Transforming growth factor βs: Biochemistry and biological activities in vivo and in vitro. In LeRoith, D. & Bondy, C, eds. Growth Factors in Health and Disease. JAI Press, Greenwich, Connecticut, pp. 319 356.
-
(1996)
, pp. 319-356
-
-
Cui, W.1
Ackhurst, R.J.2
-
6
-
-
0027366905
-
Effects of TGFβs and bFGF on astroglial cell growth and gene expression in vitro.
-
Flanders, K., Ludecke, G., Renzing, J., Hamm, C., Cissel, D., Unsicker, K. 1993 Effects of TGFβs and bFGF on astroglial cell growth and gene expression in vitro. Mol. Cell. Neurosci., 4, 406 417.
-
(1993)
Mol. Cell. Neurosci.
, vol.4
, pp. 406-417
-
-
Flanders, K.1
Ludecke, G.2
Renzing, J.3
Hamm, C.4
Cissel, D.5
Unsicker, K.6
-
7
-
-
0028993427
-
Rapid TGFβ1 effects on actin cytoskeleton of astrocytes: comparison with other factors and implications for cell motility.
-
Gagelin, C., Pierre, M., Gaveret, J.‐M., Toru‐Delbauffe, D. 1995 Rapid TGFβ1 effects on actin cytoskeleton of astrocytes: comparison with other factors and implications for cell motility. Glia, 13, 283 293.
-
(1995)
Glia
, vol.13
, pp. 283-293
-
-
Gagelin, C.1
Pierre, M.2
Gaveret, J.‐M.3
Toru‐Delbauffe, D.4
-
8
-
-
0027473684
-
Human anti‐self antibodies with high specificity from phage display libraries.
-
Griffiths, A.D., Malmqvist, M., Marks, J.D., Bye, J.M., Embleton, M.J., McCafferty, J., Baier, M., Holliger, K.P., Gorick, B.D., Hughes‐Jones, N.C. 1993 Human anti‐self antibodies with high specificity from phage display libraries. EMBO J., 12, 725 734.
-
(1993)
EMBO J.
, vol.12
, pp. 725-734
-
-
Griffiths, A.D.1
Malmqvist, M.2
Marks, J.D.3
Bye, J.M.4
Embleton, M.J.5
McCafferty, J.6
Baier, M.7
Holliger, K.P.8
Gorick, B.D.9
Hughes‐Jones, N.C.10
-
9
-
-
85120517638
-
Transforming growth factor β switches the pattern of integrins expressed in MG‐63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin.
-
Heino, J. & Massague, J. 1989 Transforming growth factor β switches the pattern of integrins expressed in MG‐63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin. J. Biol. Chem., 36, 21 806 21 811.
-
(1989)
J. Biol. Chem.
, vol.36
, pp. 21 806-21
-
-
Heino, J.1
Massague, J.2
-
10
-
-
0028967734
-
Tumour necrosis factor alpha and transforming growth factor β upregulate astrocyte expression of monocyte chemoattractant protein – 1.
-
Hurwitz, A., Lyman, W., Berman, J. 1995 Tumour necrosis factor alpha and transforming growth factor β upregulate astrocyte expression of monocyte chemoattractant protein – 1. J. Neuroimmunol., 57, 193 198.
-
(1995)
J. Neuroimmunol.
, vol.57
, pp. 193-198
-
-
Hurwitz, A.1
Lyman, W.2
Berman, J.3
-
11
-
-
0024495948
-
Regulation of cell adhesion receptors by transforming growth factor β. Regulation of vitronectin receptor and LFA‐1.
-
Ignotz, R.A., Heino, J., Massague, J. 1989 Regulation of cell adhesion receptors by transforming growth factor β. Regulation of vitronectin receptor and LFA‐1. J. Biol. Chem., 264, 389 392.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 389-392
-
-
Ignotz, R.A.1
Heino, J.2
Massague, J.3
-
12
-
-
0023025366
-
Transforming growth factor β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.
-
Ignotz, R.A. & Massague, J. 1989 Transforming growth factor β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J. Biol. Chem, 261, 4337 4345.
-
(1989)
J. Biol. Chem
, vol.261
, pp. 4337-4345
-
-
Ignotz, R.A.1
Massague, J.2
-
13
-
-
0031813396
-
Antigen specificity and tumour targeting efficiency of a human CEA specific scFv and affinity matured derivatives.
-
Jackson, H., Bacon, L., Pedley, B., Derbyshire, E., Field, A., Osbourn, J., Allen, D. 1998 Antigen specificity and tumour targeting efficiency of a human CEA specific scFv and affinity matured derivatives. Brit. J. Cancer., in press.
-
(1998)
Brit. J. Cancer.
-
-
Jackson, H.1
Bacon, L.2
Pedley, B.3
Derbyshire, E.4
Field, A.5
Osbourn, J.6
Allen, D.7
-
14
-
-
0025344028
-
TGFβ1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence.
-
Kerr, L.D., Miller, D.B., Matrisian, L.M. 1990 TGFβ1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence. Cell, 61, 267 278.
-
(1990)
Cell
, vol.61
, pp. 267-278
-
-
Kerr, L.D.1
Miller, D.B.2
Matrisian, L.M.3
-
15
-
-
0028243703
-
Elevation of transforming growth factor‐β in cerebrospinal fluid of patients with communicating hydrocephalus after sub‐arachnoid haemorrhage.
-
Kitazawa, K. & Tada, T. 1994 Elevation of transforming growth factor‐β in cerebrospinal fluid of patients with communicating hydrocephalus after sub‐arachnoid haemorrhage. Stroke, 25, 1400 1404.
-
(1994)
Stroke
, vol.25
, pp. 1400-1404
-
-
Kitazawa, K.1
Tada, T.2
-
16
-
-
0029879741
-
Increased expression of TGF‐β in brain tissue after ischemic stroke in humans.
-
Krupinski, J., Kumar, P., Kumar, S., Kaluza, J. 1996 Increased expression of TGF‐β in brain tissue after ischemic stroke in humans. Stroke, 27, 852 857.
-
(1996)
Stroke
, vol.27
, pp. 852-857
-
-
Krupinski, J.1
Kumar, P.2
Kumar, S.3
Kaluza, J.4
-
17
-
-
0025148995
-
Transforming growth factor β1 modulates the effects of basic fibroblast growth factor on growth and phenotypic expression of rat astroblasts in vitro.
-
Labourdette, G., Thiery, J., Laeng, P., Perraud, F., Lawrence, D., Pettman, B. 1990 Transforming growth factor β1 modulates the effects of basic fibroblast growth factor on growth and phenotypic expression of rat astroblasts in vitro. J. Cell Biol., 144, 473 484.
-
(1990)
J. Cell Biol.
, vol.144
, pp. 473-484
-
-
Labourdette, G.1
Thiery, J.2
Laeng, P.3
Perraud, F.4
Lawrence, D.5
Pettman, B.6
-
18
-
-
0022976357
-
Enhanced production and extracellular deposition of the endothelial‐type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor β.
-
Laiho, M., Saksela, O., Andreasen, P.A., Keski‐Oja, J. 1986 Enhanced production and extracellular deposition of the endothelial‐type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor β. J. Cell Biol., 103, 2403 2410.
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2403-2410
-
-
Laiho, M.1
Saksela, O.2
Andreasen, P.A.3
Keski‐Oja, J.4
-
19
-
-
85013517436
-
Cellular response of central nervous system tissue to invasive therapeutic measures.
-
Logan, A. & Berry, M. 1994 Cellular response of central nervous system tissue to invasive therapeutic measures. Meth. Neurosci., 21, 3 19.
-
(1994)
Meth. Neurosci.
, vol.21
, pp. 3-19
-
-
Logan, A.1
Berry, M.2
-
20
-
-
0028230259
-
Effects of transforming growth factor β1 on scar production in the injured central nervous system.
-
Logan, A., Berry, M., Gonzalez, A.M., Frautschy, S.A., Sporn, M.B., Baird, A. 1994 Effects of transforming growth factor β1 on scar production in the injured central nervous system. Eur. J. Neurosci., 6, 355 363.
-
(1994)
Eur. J. Neurosci.
, vol.6
, pp. 355-363
-
-
Logan, A.1
Berry, M.2
Gonzalez, A.M.3
Frautschy, S.A.4
Sporn, M.B.5
Baird, A.6
-
21
-
-
0026699984
-
Enhanced expression of transforming growth factor β1 in the rat brain after a localised cerebral injury.
-
Logan, A., Frautschy, S.A., Gonzalez, A.M., Sporn, M.B., Baird, A. 1992 Enhanced expression of transforming growth factor β1 in the rat brain after a localised cerebral injury. Brain Res., 587, 216 225.
-
(1992)
Brain Res.
, vol.587
, pp. 216-225
-
-
Logan, A.1
Frautschy, S.A.2
Gonzalez, A.M.3
Sporn, M.B.4
Baird, A.5
-
22
-
-
0026091525
-
Generation of antibodies and assays for transforming growth factor β.
-
Lucas, C., Fendly, B.M., Mukku, V.R., Wong, W.L., Palladino, M.A. 1991 Generation of antibodies and assays for transforming growth factor β. Meth. Enzymol., 198, 303 316.
-
(1991)
Meth. Enzymol.
, vol.198
, pp. 303-316
-
-
Lucas, C.1
Fendly, B.M.2
Mukku, V.R.3
Wong, W.L.4
Palladino, M.A.5
-
23
-
-
0023337921
-
Transforming growth factor‐β is a strong and fast acting positive regulator of the level of type‐1 plasminogen activator‐inhibitor mRNA in WI‐38 human lung fibroblasts.
-
Lund, L.R., Riccio, A., Andreasen, P.A., Nielsen, L.S., Kristensen, P., Laiho, M., Saksela, O., Blasi, F., Dano, K. 1987 Transforming growth factor‐β is a strong and fast acting positive regulator of the level of type‐1 plasminogen activator‐inhibitor mRNA in WI‐38 human lung fibroblasts. EMBO J., 6, 1281 1286.
-
(1987)
EMBO J.
, vol.6
, pp. 1281-1286
-
-
Lund, L.R.1
Riccio, A.2
Andreasen, P.A.3
Nielsen, L.S.4
Kristensen, P.5
Laiho, M.6
Saksela, O.7
Blasi, F.8
Dano, K.9
-
24
-
-
0026317443
-
By‐passing immunization: Human antibodies from V‐gene libraries displayed on phage.
-
Marks, J.D., Hoogenboom, H.R., Bonnert, T.P., McCafferty, J., Griffiths, A.D., Winter, G. 1991 By‐passing immunization: Human antibodies from V‐gene libraries displayed on phage. J. Mol. Biol., 222, 581 597.
-
(1991)
J. Mol. Biol.
, vol.222
, pp. 581-597
-
-
Marks, J.D.1
Hoogenboom, H.R.2
Bonnert, T.P.3
McCafferty, J.4
Griffiths, A.D.5
Winter, G.6
-
25
-
-
0030700632
-
Targeting by affinity‐matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform.
-
Neri, D., Carnemolla, B., Nissim, A., Leprini, A., Querze, G., Balza, E., Pini, L., Tarli, A., Halin, C., Neri, P., Zardi, L., Winter, G. 1997 Targeting by affinity‐matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform. Nature Biotech., 15, 1271 1275.
-
(1997)
Nature Biotech.
, vol.15
, pp. 1271-1275
-
-
Neri, D.1
Carnemolla, B.2
Nissim, A.3
Leprini, A.4
Querze, G.5
Balza, E.6
Pini, L.7
Tarli, A.8
Halin, C.9
Neri, P.10
Zardi, L.11
Winter, G.12
-
26
-
-
0031106404
-
Transforming growth factor‐β: Vasculogenesis, angiogenesis and vessel wall integrity.
-
Pepper, M.S. 1997 Transforming growth factor‐β: Vasculogenesis, angiogenesis and vessel wall integrity. Cytokine Growth Factor Rev., 8, 21 43.
-
(1997)
Cytokine Growth Factor Rev.
, vol.8
, pp. 21-43
-
-
Pepper, M.S.1
-
27
-
-
0031428894
-
TGF‐βs in the central nervous system: Potential roles in ischaemic injury and neurodegenerative diseases.
-
Pratt, B.M. & McPherson, J.M. 1997 TGF‐βs in the central nervous system: Potential roles in ischaemic injury and neurodegenerative diseases. Cytokine Growth Factor Rev., 8, 267 292.
-
(1997)
Cytokine Growth Factor Rev.
, vol.8
, pp. 267-292
-
-
Pratt, B.M.1
McPherson, J.M.2
-
28
-
-
0027203746
-
A novel, sensitive bioassay for transforming growth factor β.
-
Randall, L.A., Wadhwa, M., Thorpe, R., Mire‐Sluis, A.R. 1993 A novel, sensitive bioassay for transforming growth factor β. J. Immunol. Meth., 164, 61 67.
-
(1993)
J. Immunol. Meth.
, vol.164
, pp. 61-67
-
-
Randall, L.A.1
Wadhwa, M.2
Thorpe, R.3
Mire‐Sluis, A.R.4
-
29
-
-
0022471924
-
Transforming growth factor type beta: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen synthesis in vitro.
-
Roberts, A.B., Sporn, M.B., Assoian, R.K., Smith, J.M., Roche, N.S., Wakefield, L.M., Heine, U.I., Liotta, L.A., Falanga, V., Kehrl, J.H., Fauci, A.S. 1986 Transforming growth factor type beta: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen synthesis in vitro. Proc. Natl Acad. Sci. USA, 83, 4167 4171.
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 4167-4171
-
-
Roberts, A.B.1
Sporn, M.B.2
Assoian, R.K.3
Smith, J.M.4
Roche, N.S.5
Wakefield, L.M.6
Heine, U.I.7
Liotta, L.A.8
Falanga, V.9
Kehrl, J.H.10
Fauci, A.S.11
-
30
-
-
0032867293
-
A fully human antibody neutralising biologically active human TGFβ2 for use in therapy.
-
Thompson, J.E., Vaughan, T.J., Williams, A.J., Wilton, J., Johnson, K.S., Bacon, L., Green, J.A., Field, R., Ruddock, S., Martins, M., Pope, A.R., Tempest, P.R., Jackson, R.H. 1999 A fully human antibody neutralising biologically active human TGFβ2 for use in therapy. J. Immunol. Meth., in press.
-
(1999)
J. Immunol. Meth.
-
-
Thompson, J.E.1
Vaughan, T.J.2
Williams, A.J.3
Wilton, J.4
Johnson, K.S.5
Bacon, L.6
Green, J.A.7
Field, R.8
Ruddock, S.9
Martins, M.10
Pope, A.R.11
Tempest, P.R.12
Jackson, R.H.13
-
31
-
-
0025241751
-
Effects of transforming growth factor β1 on astroglial cells in culture.
-
Toru‐Delbauffe, D., Baghdassarian‐Chalaye, D., Gaveret, J.M., Courtin, F., Pomerance, M., Pierre, M. 1990 Effects of transforming growth factor β1 on astroglial cells in culture. J. Neurochem., 54, 1056 1061.
-
(1990)
J. Neurochem.
, vol.54
, pp. 1056-1061
-
-
Toru‐Delbauffe, D.1
Baghdassarian‐Chalaye, D.2
Gaveret, J.M.3
Courtin, F.4
Pomerance, M.5
Pierre, M.6
-
32
-
-
0023631004
-
Transforming growth factor beta causes a persistent increase in steady‐state amounts for type I and type III collagen and fibronectin mRNAs in normal dermal human fibroblasts.
-
Varga, J., Rosenbloom, J., Jimenez, S.A. 1987 Transforming growth factor beta causes a persistent increase in steady‐state amounts for type I and type III collagen and fibronectin mRNAs in normal dermal human fibroblasts. Biochem. J., 297, 597 604.
-
(1987)
Biochem. J.
, vol.297
, pp. 597-604
-
-
Varga, J.1
Rosenbloom, J.2
Jimenez, S.A.3
-
33
-
-
9344223986
-
Human antibodies with sub‐nanomolar affinities isolated from a large non‐immunized phage display library.
-
Vaughan, T.J., Williams, A.J., Pritchard, K., Osbourn, J.K., Pope, A.R., Earnshaw, J.C., McCafferty, J., Hodits, R.A., Wilton, J., Johnson, K.S. 1996 Human antibodies with sub‐nanomolar affinities isolated from a large non‐immunized phage display library. Nature Biotech., 14, 309 314.
-
(1996)
Nature Biotech.
, vol.14
, pp. 309-314
-
-
Vaughan, T.J.1
Williams, A.J.2
Pritchard, K.3
Osbourn, J.K.4
Pope, A.R.5
Earnshaw, J.C.6
McCafferty, J.7
Hodits, R.A.8
Wilton, J.9
Johnson, K.S.10
-
34
-
-
2342496439
-
Transforming growth factor β induces monocyte chemotaxis and growth factor production.
-
Wahl, S.M., Hunt, D.A., Wakefield, L.M., McCartney‐Francis, N., Wahl, L.M., Roberts, A.B., Sporn, M.B. 1987 Transforming growth factor β induces monocyte chemotaxis and growth factor production. Proc. Natl Acad. Sci. USA, 84, 5788 5792.
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 5788-5792
-
-
Wahl, S.M.1
Hunt, D.A.2
Wakefield, L.M.3
McCartney‐Francis, N.4
Wahl, L.M.5
Roberts, A.B.6
Sporn, M.B.7
-
35
-
-
0022910335
-
The effects of platelet‐derived transforming growth factor‐β on normal diploid gingival fibroblasts.
-
Wrana, J.L., Sodek, J., Ber, R.L., Bellows, C.G. 1986 The effects of platelet‐derived transforming growth factor‐β on normal diploid gingival fibroblasts. Eur. J. Biochem., 159, 69 76.
-
(1986)
Eur. J. Biochem.
, vol.159
, pp. 69-76
-
-
Wrana, J.L.1
Sodek, J.2
Ber, R.L.3
Bellows, C.G.4
-
36
-
-
0030764732
-
Amyloidogenic role of cytokine TGF‐β1 in transgenic mice and in Alzheimer’s disease.
-
Wyss‐Coray, T., Masliah, E., Mallory, M., McConlogue, L., Johnson‐Wood, K., Lin, C., Mucke, L. 1997 Amyloidogenic role of cytokine TGF‐β1 in transgenic mice and in Alzheimer’s disease. Nature, 389, 603 606.
-
(1997)
Nature
, vol.389
, pp. 603-606
-
-
Wyss‐Coray, T.1
Masliah, E.2
Mallory, M.3
McConlogue, L.4
Johnson‐Wood, K.5
Lin, C.6
Mucke, L.7
|