SIRC-CVS cytotoxicity test: An alternative for predicting rodent acute systemic toxicity

Journal of Toxicological Sciences

Volumn 31, Issue 4, 2006, Pages 371-379

  Kitagaki, Masato ^a   Wakuri, Shinobu ^b   Hirota, Morihiko ^a   Tanaka, Noriho ^b   Itagaki, Hiroshi ^a  

^a Quality Assurance Center   (Japan)

^b HATANO RESEARCH INSTITUTE   (Japan)

Author keywords

Acute systemic toxicity; IC50; In vitro alternative; LD50; SIRC CVS

Indexed keywords

6 METHYLCOUMARIN; ACETYLSALICYLIC ACID; ACRYLAMIDE; ACRYLONITRILE; ALCOHOL; ATROPINE; CADMIUM CHLORIDE; CARBON TETRACHLORIDE; CHLORAMPHENICOL; CHLORPROMAZINE; CITRIC ACID TRIETHYL ESTER; COBALT CHLORIDE; COPPER SULFATE; CRESOL; CRYSTAL VIOLET; FLUFENAMIC ACID; FLUORIDE SODIUM; GLYCEROL; PHENOL; PHENYLENEDIAMINE; PHENYTOIN; PHTHALIC ACID DIBUTYL ESTER; PROPRANOLOL DERIVATIVE; SALICYLATE SODIUM; SILVER NITRATE; THEOPHYLLINE; THYMOL; TOLBUTAMIDE; UNINDEXED DRUG; VERAPAMIL;

ACUTE TOXICITY; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CORNEA CELL; CYTOTOXICITY; IC 50; IN VITRO STUDY; IN VIVO STUDY; LD 50; MOUSE; NONHUMAN; RAT; SENSITIVITY AND SPECIFICITY; STAINING; TOXICITY; TOXICITY TESTING;

ORYCTOLAGUS CUNICULUS; RODENTIA;

EID: 33750897909     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.31.371     Document Type: Article

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