Discontinuous and continuous separation of the monomeric and dimeric forms of human bone morphogenetic protein-2 from renaturation batches

Journal of Chromatography A

Volumn 1135, Issue 2, 2006, Pages 142-150

  Gueorguieva, Ludmila ^a   Vallejo, Luis Felipe ^b   Rinas, Ursula ^b   Seidel Morgenstern, Andreas ^a,c  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

Author keywords

Bone morphogenetic protein 2; Continuous counter current separation; Gradient elution; Step gradients

Indexed keywords

BONE; COMPUTER SIMULATION; DIMERS; DRUG PRODUCTS; ESCHERICHIA COLI; GROWTH (MATERIALS); MONOMERS;

BONE MORPHOGENETIC PROTEIN; CONTINUOUS COUNTER CURRENT SEPARATION; GRADIENT ELUTION; STEP GRADIENTS;

PROTEINS;

BONE MORPHOGENETIC PROTEIN 2; HEPARIN;

ARTICLE; CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); PRIORITY JOURNAL; PROTEIN PURIFICATION; RENATURATION; SEPARATION TECHNIQUE; SIMULATION;

BONE MORPHOGENETIC PROTEINS; CHROMATOGRAPHY, LIQUID; DIMERIZATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; HEPARIN; PROTEIN RENATURATION; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY, ULTRAVIOLET; TRANSFORMING GROWTH FACTOR BETA;

ESCHERICHIA COLI;

EID: 33750843738     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2006.08.061     Document Type: Article

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