Inhibitors of Plasmepsin II-potential antimalarial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 24, 2006, Pages 6194-6199

  Corminboeuf, Olivier ^a   Dunet, Guillaume ^b   Hafsi, Mehdi ^c   Grimont, Julien ^b   Grisostomi, Corinna ^a   Meyer, Solange ^a   Binkert, Christoph ^a   Bur, Daniel ^a   Jones, Andrew ^a   Prade, Lars ^a   Brun, Reto ^d   Boss, Christoph ^a  

^a ACTELION PHARMACEUTICALS LTD   (Switzerland)

^b Ecole Nationale Superieure de Chimie de Mulhouse   (France)

^c Ecole d'Ingenieurs et d'Architectes de Fribourg   (Switzerland)

^d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Malaria; Plasmepsin II

Indexed keywords

ANTIMALARIAL AGENT; ASPARTIC PROTEINASE; HEMOGLOBIN; PLASMEPSIN II; PLASMEPSIN II INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CATABOLISM; CELL ASSAY; CONTROLLED STUDY; DEGRADATION; ENZYME INHIBITION; ERYTHROCYTE; HUMAN; HUMAN CELL; PLASMODIUM FALCIPARUM; PROTOZOAL INFECTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; ASPARTIC ENDOPEPTIDASES; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE; ENZYME INHIBITORS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM;

EID: 33750740732     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.09.027     Document Type: Article

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